Chiral liquid membrane separation is crucial in pharmaceuticals and chemical synthesis for its simplicity and stability, yet designing membrane carriers that enable efficient enantioseparation remains a challenge. Here, we demonstrated for the first time that chiral porous materials can act as mobile carriers of bulk liquid membranes (BLMs) to enhance enantioselective transport and separation. We design

Towards complex coupled molecular motions, the remote handedness inversion of a helicene moiety was achieved by a rotary molecular motor. The use of a specifically engineered dynamic helicene stator in a novel overcrowded‐alkene second‐generation molecular motor based on a fluorinated dibenzofluorene fragment allows for an unprecedented control over helicity inversion. This is achieved by the mechanical

Chiral 2‐azetines and allenes are highly valuable structural units in natural products and useful chemicals. However, enantioselective synthesis of both 2‐azetines and allenes has been extremely challenging. Herein, we present asymmetric construction of chiral 2‐azetines (70–98% yields and up to 96% ee) through chiral phosphine‐catalyzed [2+2] annulation of yne‐enones with sulfamate‐derived cyclic

The practical energy density of lithium‐sulfur batteries is limited by the low sulfur utilization at lean electrolyte conditions. The highly solvating electrolytes (HSEs) promise to address the issue at harsh conditions, but the conflicting challenges of long‐term stability of radical‐mediated sulfur redox reactions (SRR) and the poor stability with lithium metal anode (LMA) have dimmed the efforts

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by memory loss and behavioral and psychological symptoms of dementia (BPSD). Given that cholinergic neurons are predominantly affected in AD, current treatments primarily aim to enhance cholinergic neurotransmission. However, imbalances in other neurotransmitters, such as γ‐aminobutyric acid (GABA), also contribute to AD symptomatology

Metal‐organic frameworks (MOFs) are lagging in the use of lithium‐ion batteries (LIBs), ascribing to full coordination between metal nodes and organic ligands, to a large extent. By integrating a modulator into a ligand with missing bridging functionality, this study elucidates the role of non‐bridging defect sites in MOFs in tailoring lithium storage performance. A fully bridged pristine MOF (p‐MOF)

Alkaline methanol‐water electrolysis system is regarded as an appealing strategy for electro‐reforming methanol into formate and producing hydrogen with low energy‐consumption compared with alkaline water electrolysis. However, stability and selectivity under high current densities for practical application remain challenging. Herein, a CeF3@Ni3N nanosheets array anchored on carbon cloth (CeF3@Ni3N/CC)

Isomerization is a key process in many (bio)chemical systems. In microbial rhodopsins, the photoinduced isomerization of the all‐trans retinal to the 13‐cis isomer initiates a cascade of structural changes of the protein. The interplay between these changes and the thermal relaxation of the isomerized retinal is one of the crucial determinants for rhodopsin functionality. It is therefore important

Fatty acid synthase (FAS) multienzymes are responsible for de novo fatty acid biosynthesis and crucial in primary metabolism. Despite extensive research, the molecular details of the FAS catalytic mechanisms are still poorly understood. For example, the b‐ketoacyl synthase (KS) catalyzes the fatty acid elongating carbon‐carbon‐bond formation, which is the key catalytic step in biosynthesis, but factors

Any polymers composed of racemic segments are obviously optically inactive and lack any chiroptical applications. Here, we present an intriguing method for precisely generating global chirality in racemic copolymer assemblies without any external asymmetrical intervention via step‐wise polymerization‐induced chiral self‐assembly (PICSA). Global supramolecular chirality of the nanoaggregates could be

Small molecule modulators are powerful tools for selectively probing and manipulating proteins in native biological systems. However, the development of versatile modulators that exhibit desired properties is hindered by the lack of a rapid and robust synthetic strategy. Here, we develop a facile and reliable one‐step methodology for the generation of multifunctional toolboxes encompassing a wide variety

Rechargeable magnesium batteries are regarded as a promising multi‐valent battery system for low‐cost and sustainable energy storage applications. Boron‐based magnesium salts with terminal substituent fluorinated anions (Mg[B(ORF)4]2, RF = fluorinated alkyl) have exhibited impressive electrochemical stability. Nevertheless, their deployment is hindered by the complicated synthesis routes and the surface

Solid state photon upconversion by triplet‐triplet annihilation (TTA), particularly near‐infrared (NIR)‐to‐blue upconversion, holds instant promise for enhancing optoelectronic and photochemical applications. Despite extensive studies, NIR‐to‐blue upconversion has remained particularly challenging and elusive due to inherent multiple energy‐downhill processes in TTA upconversion. In this study, using

Rechargeable magnesium batteries are promising for future energy storage. However, among other challenges, their practical application is hindered by low coulombic efficiencies of magnesium plating and stripping. Fundamental processes such as the formation, structure, and stability of passivation layers and the influence of different electrolyte components on them are still not fully understood. In

It is a huge challenge to integrate comprehensive properties in photothermal materials for multifunctional application in various aspects of water cleaning and purification. In this study, inspired by honeycombs, a polysiloxane/polyimide/carbon composite hydrophobic aerogel (Bio-SPC aerogel) is fabricated using a blending-crosslinking-directional freezing-gradient heating method, and exhibits reasonable

Non-aqueous biphasic absorbents have excellent energy-saving features in capturing CO2. However, the high hygroscopicity of chemical absorbents and the moisture content in flue gas can alter the moisture content of absorbents, thereby affecting their carbon capture performance and stability. In this research, an absorbent for solid–liquid phase transition composed of N-Aminoethylpiperazine (AEP) and

Since fossil-fuel power plants emit humid flue gases, the competitive adsorption of CO2 with H2O is inevitable for adsorptive carbon capture technologies. Nitrogen- and oxygen-containing functional groups can enhance adsorption capacity and selectivity of biochar. However, the interaction between N/O functional groups and CO2 in the presence of H2O is not clarified. In this study, a series of nitrogen-doped

Activating the lattice oxygen can significantly improve the kinetics of oxygen evolution reaction (OER), however, it often results in reduced stability due to the bulk structure degradation. Here, we develop a spinel Fe0.3Co0.9Cr1.8O4 with active lattice oxygen by high-throughput methods, achieving high OER activity and stability, superior to the benchmark IrO2. The oxide exhibits an ultralow overpotential

Membrane electrolytes are key to constructing planar energy storage devices of low thickness and high flexibility, requesting simultaneous optimization of ionic conductivity and mechanical stability. Herein, aqueous phase electrospinning (APE) was implemented to co-spin polyvinyl alcohol and pullulan polysaccharide for fabricating crosslinked fibrous membrane electrolytes. While the hydroxyl-rich polymeric

Developing high-performance solid-state batteries requires solid electrolytes with high ionic conductivity and excellent electrode compatibility. This study focuses on bimetallic borohydride NaZn(BH4)3·xTHF, revealing a room temperature sodium conductivity of 1.89 × 10−5 S cm−1 due to the formation of Na-O bonds. This THF-involved NaZn(BH4)3 was synthesized in a THF solution without ball milling. Our

The blood–brain barrier (BBB) caused limited drug accumulation and programmed death-ligand 1 (PD-L1) compromised immunosuppressive microenvironment are bottlenecks in glioblastoma multiforme (GBM) treatment. Herein, we bioengineered a human heavy chain nanoferritin (HTE NPs) for GBM-specific delivery and efficient immunotherapy. To achieve targeted mitochondrial metabolic regulation, we connected

Bismuth-based oxides are promising electrolyte materials for Reversible Solid Oxide Cells (RSOCs) due to their high ion conductivity and rapid surface oxygen exchange kinetics. In this work we propose a multi-element doping strategy to obtain a novel Dy0.06Gd0.02Er0.02Bi1.9O3 (DGESB) quaternary oxide bismuth material whose ionic conductivities and crystal structure are characterized by AC impedance

Sonodynamic therapy (SDT) shows potential for noninvasive eradication of local solid tumors. However, its efficacy in suppressing metastatic tumors is limited by factors such as insufficient tumor accumulation, the immunosuppressive tumor microenvironment, and acquired immune tolerance. To address these challenges, we developed self-delivering sonodynamic nanomedicine incorporating Toll-like receptor

The solubility performance of 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane has been investigated by the combination of experimental measurement, solvent parameter analysis, and molecular simulation methods. The solubility in 10 pure solvents at 293.15 K to 343.15 K was determined. It was found that the solubility in nine solvents increased with temperature, except for isoamyl propionate