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Foundation models in healthcare require rethinking reliability Nat. Mach. Intell. (IF 18.8) Pub Date : 2024-11-11 Thomas Grote, Timo Freiesleben, Philipp Berens
A new class of AI models, called foundation models, has entered healthcare. Foundation models violate several basic principles of the standard machine learning paradigm for assessing reliability, making it necessary to rethink what guarantees are required to establish warranted trust in them.
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Two places at once: superposed crystal could test whether gravity obeys quantum laws Nature (IF 50.5) Pub Date : 2024-11-11
Method could probe whether a key tenet of quantum mechanics applies to gravity, which has so far resisted quantum theory.
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How I’m turning seaweed into biofuel for cars on Barbados Nature (IF 50.5) Pub Date : 2024-11-11
Mechanical engineer Legena Henry converts sargassum and rum-distillery waste water to produce sustainable natural gas for vehicles.
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AI protein-prediction tool AlphaFold3 is now open source Nature (IF 50.5) Pub Date : 2024-11-11
The code underlying the Nobel-prize-winning tool for modelling protein structures can now be downloaded by academics.
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Grass-roots grant-writing approaches can help researchers at small institutions to succeed Nature (IF 50.5) Pub Date : 2024-11-11
At small or minority-serving institutions, time and resources that are needed to draft successful grant proposals are often in short supply. But help is available.
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Cosmic connections: our changing vision of the heavens Nature (IF 50.5) Pub Date : 2024-11-11
From maps of the stars to the multiverse, four enlightening art shows reveal diverse impressions of the cosmos.
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Circular logic: understanding RNA’s strangest form yet Nature (IF 50.5) Pub Date : 2024-11-11
Circular RNAs are prevalent, mysterious and fascinating, but their study requires great care.
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Daily briefing: First DNA from Pompeii body casts illuminates who victims were Nature (IF 50.5) Pub Date : 2024-11-08
Remains recovered from plaster casts of five people who died in the eruption of Mount Vesuvius have overturned some old assumptions about who they were. Plus, mitochondria can split into two different forms under stress.
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Emissions from private jets are soaring Nature (IF 50.5) Pub Date : 2024-11-08
The popularity of private planes, the distance covered by flights and associated greenhouse-gas production are all on the rise.
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Should Alzheimer’s be diagnosed without symptoms? Proposal to rely on blood tests roils scientists Nature (IF 50.5) Pub Date : 2024-11-08
Some researchers seek to establish a single abnormal result on a set of biomarker-based tests as sufficient to diagnose the disease.
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Reusability report: exploring the utility of variational graph encoders for predicting molecular toxicity in drug design Nat. Mach. Intell. (IF 18.8) Pub Date : 2024-11-08 Ruijiang Li, Jiang Lu, Ziyi Liu, Duoyun Yi, Mengxuan Wan, Yixin Zhang, Peng Zan, Song He, Xiaochen Bo
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‘Rapture and beauty’: a writer’s portrait of the International Space Station Nature (IF 50.5) Pub Date : 2024-11-08
Samantha Harvey talks to Nature about her book Orbital
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What Trump’s election win could mean for AI, climate and health Nature (IF 50.5) Pub Date : 2024-11-08
Donald Trump made numerous promises during his presidential campaign that could affect scientists and science policy. Will they be implemented once he is president?
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World-first stem-cell treatment restores vision in people Nature (IF 50.5) Pub Date : 2024-11-08
The treatment, given to four people with damaged corneas, seems safe but needs to be tested in larger trials.
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This scientist treated her own cancer with viruses she grew in the lab Nature (IF 50.5) Pub Date : 2024-11-08
Virologist Beata Halassy says self-treatment worked and was a positive experience — but researchers warn that it is not something others should try.
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Grass-roots pressure grows to boost support for breastfeeding scientists Nature (IF 50.5) Pub Date : 2024-11-08
Norway offers up to 2 hours of paid time per day for breastfeeding. Why do other countries’ parental support policies lag so far behind?
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Evolving antibody response to SARS-CoV-2 antigenic shift from XBB to JN.1 Nature (IF 50.5) Pub Date : 2024-11-07 Fanchong Jian, Jing Wang, Ayijiang Yisimayi, Weiliang Song, Yanli Xu, Xiaosu Chen, Xiao Niu, Sijie Yang, Yuanling Yu, Peng Wang, Haiyan Sun, Lingling Yu, Jing Wang, Yao Wang, Ran An, Wenjing Wang, Miaomiao Ma, Tianhe Xiao, Qingqing Gu, Fei Shao, Youchun Wang, Zhongyang Shen, Ronghua Jin, Yunlong Cao
The continuous evolution of SARS-CoV-2, particularly the emergence of BA.2.86/JN.1 lineage replacing XBB, necessitates re-evaluation of vaccine compositions 1–3. Here, we provide a comprehensive analysis of the humoral immune response to XBB and JN.1 human exposure. We demonstrate the antigenic distinctiveness of XBB and JN.1 lineages in SARS-CoV-2-naive individuals, and JN.1 infection elicits superior
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Will South Africa become first country to accept controversial form of human genome editing? Nature (IF 50.5) Pub Date : 2024-11-07
Scientists raise the alarm following updated research ethics guidelines on heritable human genome editing.
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First DNA from Pompeii body casts illuminates who victims were Nature (IF 50.5) Pub Date : 2024-11-07
The sex and ancestry of five people who died in the eruption are revealed by genetic material embedded in the casts.
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Why do wet dogs shake themselves dry? Neuroscience has an answer Nature (IF 50.5) Pub Date : 2024-11-07
Deciphering how mammals respond to sensations through their fur could inspire further research on skin sensitivity.
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Daily briefing: World’s first wooden satellite heads for space Nature (IF 50.5) Pub Date : 2024-11-07
A satellite made of wood has been sent to the International Space Station, where it’ll later be released into orbit. Plus, we learn that snapshots of atomic nuclei smashing together can show us what shape they were.
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No hearing aids needed: bats’ ears stay keen well into old age Nature (IF 50.5) Pub Date : 2024-11-06
Elderly big brown bats showed little sign of age-related degradation in the inner ear.
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Bioelastic state recovery for haptic sensory substitution Nature (IF 50.5) Pub Date : 2024-11-06 Matthew T. Flavin, Kyoung-Ho Ha, Zengrong Guo, Shupeng Li, Jin-Tae Kim, Tara Saxena, Dimitrios Simatos, Fatimah Al-Najjar, Yuxuan Mao, Shishir Bandapalli, Chengye Fan, Dongjun Bai, Zhuang Zhang, Yanlin Zhang, Eunhye Flavin, Kenneth E. Madsen, Yi Huang, Luoqian Emu, Jingyang Zhao, Jae-Young Yoo, Minsu Park, Jaeho Shin, Aaron G. Huang, Hee-Sup Shin, J. Edward Colgate, Yonggang Huang, Zhaoqian Xie, Hanqing
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New CERN chief pledges to forge ahead with $17-billion supercollider Nature (IF 50.5) Pub Date : 2024-11-07
Physicist Mark Thomson will face several challenges — including bringing in enough money to build a colossal new particle-smashing ‘Higgs factory’.
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A Survey on Security of UAV Swarm Networks: Attacks and Countermeasures ACM Comput. Surv. (IF 23.8) Pub Date : 2024-11-08 Xiaojie Wang, Zhonghui Zhao, Ling Yi, Zhaolong Ning, Lei Guo, F. Richard Yu, Song Guo
The increasing popularity of Unmanned Aerial Vehicle (UAV) swarms is attributed to their ability to generate substantial returns for various industries at a low cost. Additionally, in the future landscape of wireless networks, UAV swarms can serve as airborne base stations, alleviating the scarcity of communication resources. However, UAV swarm networks are vulnerable to various security threats that
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Deep Graphical and Temporal Neuro-Fuzzy Methodology for Automatic Modulation Recognition in Cognitive Wireless Big Data IEEE Trans. Fuzzy Syst. (IF 10.7) Pub Date : 2024-11-08 Xin Jian, Qing Wang, Yaoyao Li, Abdullah Alharbi, Keping Yu, Victor C.M. Leung
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Distributed Fuzzy Formation Control for Nonlinear Multiagent Systems Under Communication Delays and Switching Topology IEEE Trans. Fuzzy Syst. (IF 10.7) Pub Date : 2024-11-08 Haodong Zhou, Yi Zuo, Shaocheng Tong
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Adaptive Fuzzy Consensus Tracking Using Monotone Tube Boundary Functions for Nonlinear MASs Under FDI Attacks: A Single-Parameter Integration Approach IEEE Trans. Fuzzy Syst. (IF 10.7) Pub Date : 2024-11-08 Ben Niu, Luyao Wen, Xudong Zhao, Guangdeng Zong, Ding Wang, Baoyi Zhang
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SDHGCN: A Heterogeneous Graph Convolutional Neural Network Combined With Shadowed Set IEEE Trans. Fuzzy Syst. (IF 10.7) Pub Date : 2024-11-08 Bin Yu, Hengjie Xie, Jingxuan Chen, Mingjie Cai, Hamido Fujita, Weiping Ding
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Don’t blame search engines for sending users to unreliable sites Nature (IF 50.5) Pub Date : 2024-11-06
Analysis of billions of pages of results from searches using the Bing algorithm suggests that reliable sites appear in search results 19 to 45 times more often than do sites with low-quality content.
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A new kind of mitochondrion Nature (IF 50.5) Pub Date : 2024-11-06
Mitochondria form two distinct subpopulations enabling them to produce essential cell components and energy, even under nutrient stress.
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Coordinated inheritance of extrachromosomal DNAs in cancer cells Nature (IF 50.5) Pub Date : 2024-11-06 King L. Hung, Matthew G. Jones, Ivy Tsz-Lo Wong, Ellis J. Curtis, Joshua T. Lange, Britney Jiayu He, Jens Luebeck, Rachel Schmargon, Elisa Scanu, Lotte Brückner, Xiaowei Yan, Rui Li, Aditi Gnanasekar, Rocío Chamorro González, Julia A. Belk, Zhonglin Liu, Bruno Melillo, Vineet Bafna, Jan R. Dörr, Benjamin Werner, Weini Huang, Benjamin F. Cravatt, Anton G. Henssen, Paul S. Mischel, Howard Y. Chang
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Selective ion transport through hydrated micropores in polymer membranes Nature (IF 50.5) Pub Date : 2024-11-06 Anqi Wang, Charlotte Breakwell, Fabrizia Foglia, Rui Tan, Louie Lovell, Xiaochu Wei, Toby Wong, Naiqi Meng, Haodong Li, Andrew Seel, Mona Sarter, Keenan Smith, Alberto Alvarez‐Fernandez, Mate Furedi, Stefan Guldin, Melanie M. Britton, Neil B. McKeown, Kim E. Jelfs, Qilei Song
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Autonomous mobile robots for exploratory synthetic chemistry Nature (IF 50.5) Pub Date : 2024-11-06 Tianwei Dai, Sriram Vijayakrishnan, Filip T. Szczypiński, Jean-François Ayme, Ehsan Simaei, Thomas Fellowes, Rob Clowes, Lyubomir Kotopanov, Caitlin E. Shields, Zhengxue Zhou, John W. Ward, Andrew I. Cooper
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Preferential occurrence of fast radio bursts in massive star-forming galaxies Nature (IF 50.5) Pub Date : 2024-11-06 Kritti Sharma, Vikram Ravi, Liam Connor, Casey Law, Stella Koch Ocker, Myles Sherman, Nikita Kosogorov, Jakob Faber, Gregg Hallinan, Charlie Harnach, Greg Hellbourg, Rick Hobbs, David Hodge, Mark Hodges, James Lamb, Paul Rasmussen, Jean Somalwar, Sander Weinreb, David Woody, Joel Leja, Shreya Anand, Kaustav Kashyap Das, Yu-Jing Qin, Sam Rose, Dillon Z. Dong, Jessie Miller, Yuhan Yao
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A cellular basis for mapping behavioural structure Nature (IF 50.5) Pub Date : 2024-11-06 Mohamady El-Gaby, Adam Loyd Harris, James C. R. Whittington, William Dorrell, Arya Bhomick, Mark E. Walton, Thomas Akam, Timothy E. J. Behrens
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Immune responses in checkpoint myocarditis across heart, blood and tumour Nature (IF 50.5) Pub Date : 2024-11-06 Steven M. Blum, Daniel A. Zlotoff, Neal P. Smith, Isabela J. Kernin, Swetha Ramesh, Leyre Zubiri, Joshua Caplin, Nandini Samanta, Sidney Martin, Mike Wang, Alice Tirard, Yuhui Song, Katherine H. Xu, Jaimie Barth, Pritha Sen, Kamil Slowikowski, Jessica Tantivit, Kasidet Manakongtreecheep, Benjamin Y. Arnold, Mazen Nasrallah, Christopher J. Pinto, Daniel McLoughlin, Monica Jackson, PuiYee Chan, Aleigha
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Identification and genetic dissection of convergent persister cell states Nature (IF 50.5) Pub Date : 2024-11-06 Sydney B. Blattman, Wenyan Jiang, E. Riley McGarrigle, Menghan Liu, Panos Oikonomou, Saeed Tavazoie
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Nucleosome flipping drives kinetic proofreading and processivity by SWR1 Nature (IF 50.5) Pub Date : 2024-11-06 Paul Girvan, Adam S. B. Jalal, Elizabeth A. McCormack, Michael T. Skehan, Carol L. Knight, Dale B. Wigley, David S. Rueda
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Mutant-selective AKT inhibition through lysine targeting and neo-zinc chelation Nature (IF 50.5) Pub Date : 2024-11-06 Gregory B. Craven, Hang Chu, Jessica D. Sun, Jordan D. Carelli, Brittany Coyne, Hao Chen, Ying Chen, Xiaolei Ma, Subhamoy Das, Wayne Kong, Adam D. Zajdlik, Kin S. Yang, Solomon H. Reisberg, Peter A. Thompson, J. Russell Lipford, Jack Taunton
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Stochastic neuropeptide signals compete to calibrate the rate of satiation Nature (IF 50.5) Pub Date : 2024-11-06 Stephen X. Zhang, Angela Kim, Joseph C. Madara, Paula K. Zhu, Lauren F. Christenson, Andrew Lutas, Peter N. Kalugin, Praneel S. Sunkavalli, Yihan Jin, Akash Pal, Lin Tian, Bradford B. Lowell, Mark L. Andermann
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A mechanism for hypoxia-induced inflammatory cell death in cancer Nature (IF 50.5) Pub Date : 2024-11-06 Abhishek Bhardwaj, Maria C. Panepinto, Beatrix Ueberheide, Benjamin G. Neel
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A multicellular developmental program in a close animal relative Nature (IF 50.5) Pub Date : 2024-11-06 Marine Olivetta, Chandni Bhickta, Nicolas Chiaruttini, John Burns, Omaya Dudin
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Central pattern generator control of a vertebrate ultradian sleep rhythm Nature (IF 50.5) Pub Date : 2024-11-06 Lorenz A. Fenk, Juan Luis Riquelme, Gilles Laurent
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Automated real-world data integration improves cancer outcome prediction Nature (IF 50.5) Pub Date : 2024-11-06 Justin Jee, Christopher Fong, Karl Pichotta, Thinh Ngoc Tran, Anisha Luthra, Michele Waters, Chenlian Fu, Mirella Altoe, Si-Yang Liu, Steven B. Maron, Mehnaj Ahmed, Susie Kim, Mono Pirun, Walid K. Chatila, Ino de Bruijn, Arfath Pasha, Ritika Kundra, Benjamin Gross, Brooke Mastrogiacomo, Tyler J. Aprati, David Liu, JianJiong Gao, Marzia Capelletti, Kelly Pekala, Lisa Loudon, Maria Perry, Chaitanya Bandlamudi
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Layered hybrid superlattices as designable quantum solids Nature (IF 50.5) Pub Date : 2024-11-06 Zhong Wan, Qi Qian, Yu Huang, Xiangfeng Duan
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Ab initio characterization of protein molecular dynamics with AI2BMD Nature (IF 50.5) Pub Date : 2024-11-06 Tong Wang, Xinheng He, Mingyu Li, Yatao Li, Ran Bi, Yusong Wang, Chaoran Cheng, Xiangzhen Shen, Jiawei Meng, He Zhang, Haiguang Liu, Zun Wang, Shaoning Li, Bin Shao, Tie-Yan Liu
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Cellular ATP demand creates metabolically distinct subpopulations of mitochondria Nature (IF 50.5) Pub Date : 2024-11-06 Keun Woo Ryu, Tak Shun Fung, Daphne C. Baker, Michelle Saoi, Jinsung Park, Christopher A. Febres-Aldana, Rania G. Aly, Ruobing Cui, Anurag Sharma, Yi Fu, Olivia L. Jones, Xin Cai, H. Amalia Pasolli, Justin R. Cross, Charles M. Rudin, Craig B. Thompson
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Intermittent rate coding and cue-specific ensembles support working memory Nature (IF 50.5) Pub Date : 2024-11-06 Matthew F. Panichello, Donatas Jonikaitis, Yu Jin Oh, Shude Zhu, Ethan B. Trepka, Tirin Moore
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Imaging shapes of atomic nuclei in high-energy nuclear collisions Nature (IF 50.5) Pub Date : 2024-11-06
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Postsynaptic competition between calcineurin and PKA regulates mammalian sleep–wake cycles Nature (IF 50.5) Pub Date : 2024-11-06 Yimeng Wang, Siyu Cao, Daisuke Tone, Hiroshi Fujishima, Rikuhiro G. Yamada, Rei-ichiro Ohno, Shoi Shi, Kyoko Matsuzawa, Saori Yada, Mari Kaneko, Hirokazu Sakamoto, Taichi Onishi, Maki Ukai-Tadenuma, Hideki Ukai, Carina Hanashima, Kenzo Hirose, Hiroshi Kiyonari, Kenta Sumiyama, Koji L. Ode, Hiroki R. Ueda
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A broadband hyperspectral image sensor with high spatio-temporal resolution Nature (IF 50.5) Pub Date : 2024-11-06 Liheng Bian, Zhen Wang, Yuzhe Zhang, Lianjie Li, Yinuo Zhang, Chen Yang, Wen Fang, Jiajun Zhao, Chunli Zhu, Qinghao Meng, Xuan Peng, Jun Zhang
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Observation of vortices in a dipolar supersolid Nature (IF 50.5) Pub Date : 2024-11-06 Eva Casotti, Elena Poli, Lauritz Klaus, Andrea Litvinov, Clemens Ulm, Claudia Politi, Manfred J. Mark, Thomas Bland, Francesca Ferlaino
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Offline ensemble co-reactivation links memories across days Nature (IF 50.5) Pub Date : 2024-11-06 Yosif Zaki, Zachary T. Pennington, Denisse Morales-Rodriguez, Madeline E. Bacon, BumJin Ko, Taylor R. Francisco, Alexa R. LaBanca, Patlapa Sompolpong, Zhe Dong, Sophia Lamsifer, Hung-Tu Chen, Simón Carrillo Segura, Zoé Christenson Wick, Alcino J. Silva, Kanaka Rajan, Matthijs van der Meer, André Fenton, Tristan Shuman, Denise J. Cai
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India–Eurasia convergence speed-up by passive-margin sediment subduction Nature (IF 50.5) Pub Date : 2024-11-06 Hao Zhou, Jiashun Hu, Luca Dal Zilio, Ming Tang, Keqing Li, Xiumian Hu
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Learning-associated astrocyte ensembles regulate memory recall Nature (IF 50.5) Pub Date : 2024-11-06 Michael R. Williamson, Wookbong Kwon, Junsung Woo, Yeunjung Ko, Ehson Maleki, Kwanha Yu, Sanjana Murali, Debosmita Sardar, Benjamin Deneen
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Electrically driven long-range solid-state amorphization in ferroic In2Se3 Nature (IF 50.5) Pub Date : 2024-11-06 Gaurav Modi, Shubham K. Parate, Choah Kwon, Andrew C. Meng, Utkarsh Khandelwal, Anudeep Tullibilli, James Horwath, Peter K. Davies, Eric A. Stach, Ju Li, Pavan Nukala, Ritesh Agarwal
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Enhancing transcription–replication conflict targets ecDNA-positive cancers Nature (IF 50.5) Pub Date : 2024-11-06 Jun Tang, Natasha E. Weiser, Guiping Wang, Sudhir Chowdhry, Ellis J. Curtis, Yanding Zhao, Ivy Tsz-Lo Wong, Georgi K. Marinov, Rui Li, Philip Hanoian, Edison Tse, Salvador Garcia Mojica, Ryan Hansen, Joshua Plum, Auzon Steffy, Snezana Milutinovic, S. Todd Meyer, Jens Luebeck, Yanbo Wang, Shu Zhang, Nicolas Altemose, Christina Curtis, William J. Greenleaf, Vineet Bafna, Stephen J. Benkovic, Anthony
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Origins and impact of extrachromosomal DNA Nature (IF 50.5) Pub Date : 2024-11-06 Chris Bailey, Oriol Pich, Kerstin Thol, Thomas B. K. Watkins, Jens Luebeck, Andrew Rowan, Georgia Stavrou, Natasha E. Weiser, Bhargavi Dameracharla, Robert Bentham, Wei-Ting Lu, Jeanette Kittel, S. Y. Cindy Yang, Brooke E. Howitt, Natasha Sharma, Maria Litovchenko, Roberto Salgado, King L. Hung, Alex J. Cornish, David A. Moore, Richard S. Houlston, Vineet Bafna, Howard Y. Chang, Serena Nik-Zainal,