Classic saturates, aromatics, resins, and asphaltenes (SARA) analysis has long enabled the chromatographic separation of complex hydrocarbon-containing products into these four families. This simplification often does not provide... more
Classic saturates, aromatics, resins, and asphaltenes (SARA) analysis has long enabled the chromatographic separation of complex hydrocarbon-containing products into these four families. This simplification often does not provide sufficient or correct information on the relationship between the composition of the products and the process variables studied. The obtention of profiles by gradient automated multiple development (AMD) is an interesting alternative to obtain extended SARA separations with increasing level of complexity for heavy petroleum products that adequately represent the entirety of the sample. An optimized 20-step gradient based on tetrahydrofuran (THF)‒dichloromethane‒n-heptane over a total migration distance of 83 mm is proposed here to characterize all types of heavy oil products. The combination of ultraviolet (UV)–densitometry (at 201, 228, and 273 nm), fluorescence detection by intensity changes using berberine cation, together with on-plate recording of UV s...
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Research Interests: Chemical Engineering, Chemistry, Analytical Chemistry, Chromatography, Petroleum, and 14 moreCoal, Medicine, Hydrocarbon, Gas Chromatography, HYDROCARBONS, Silica Gel, Reproducibility of Results, Food Sciences, Densitometry, Quntitative Thin Layer Chromatography, Toluene, Dichloromethane, Thin Layer Chromatography, and Reference standards
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Heterostructures of two-dimensional (2D) materials using graphene and MoS2 have enabled both pivotal fundamental studies and unprecedented sensing properties. These heterosystems are intriguing when graphene and MoS2 are interfaced with... more
Heterostructures of two-dimensional (2D) materials using graphene and MoS2 have enabled both pivotal fundamental studies and unprecedented sensing properties. These heterosystems are intriguing when graphene and MoS2 are interfaced with 2D sheets that emulate biomolecules, such as amino-terminated oligoglycine self-assemblies (known as tectomers). The adsorption of tectomer sheets over graphene and MoS2 modulates the physicochemical properties through electronic charge migration and mechanical stress transfer. Here, we present a systematic study by Raman spectroscopy and tectomer-functionalised scanning probe microscopy to understand mechanical strain, charge transfer and binding affinity in tectomer/graphene and tectomer/MoS2 hybrid structures. Raman mapping reveals distinctive thickness dependence of tectomer-induced charge transfer to MoS2, showing p-doping on monolayer MoS2 and n-doping on multilayer MoS2. By contrast, graphene is n-doped by tectomer independently of layer numbe...
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Resumen del trabajo presentado a la XXXVII Reunion Bienal de la Real Sociedad Espanola de Quimica, celebrada en Donostia-San Sebastian del 26 al 30 de mayo de 2019.
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Resumen del trabajo presentado al 23rd International Symposium for High-Performance Thin-Layer Chromatography (HPTLC), celebrado en Berlin (Alemania) del 4 al 8 de julio de 2017.
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Resumen del poster presentado a la 6a Jornada de Jovenes Investigadores en Fisica y Quimica de Aragon celebrada en Zaragoza el 20 de noviembre de 2014.
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En este trabajo se ha desarrollado un método semicuantitativo para la determinación de Saturados en cuatro productos de petróleo por la técnica HPTLC-densitometría por fluorescencia inducida. Para ello, se optimizaron las condiciones de... more
En este trabajo se ha desarrollado un método semicuantitativo para la determinación de Saturados en cuatro productos de petróleo por la técnica HPTLC-densitometría por fluorescencia inducida. Para ello, se optimizaron las condiciones de separación y detección de los Saturados.Se estudiaron tres tecnologías de separación diferentes: cámara vertical, cámara horizontal y AMD. En cuanto a condiciones de detección, se estudiaron la respuesta de alcanos individuales usando dos inductores de fluorescencia (berberina y primulina) a dos concentraciones diferentes. Además, se estudiaron las respuestas individuales de diferentes alcanos en el sistema para elegir un patrón mezcla de alcanos para el calibrado de los Saturados en las muestras, que se realizó mediante los métodos de adición estándar y patrón externo.Se discutirá la validez de la elección y los resultados obtenidos. En el caso del aceite de base, se compararán a dos valores de referencia obtenidos en dos laboratorios diferentes.<...
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[ES] Uso de tectómeros de oligoglicinas como transportadores multifuncionales. La presente invención se refiere al uso de los tectómeros de oligoglicinas como vehículo biocompatible para el transporte de sustancias tanto con carácter... more
[ES] Uso de tectómeros de oligoglicinas como transportadores multifuncionales. La presente invención se refiere al uso de los tectómeros de oligoglicinas como vehículo biocompatible para el transporte de sustancias tanto con carácter hidrofóbico como hidrofílico, caracterizado porque esta sustancia se incorpora y libera del tectómero mediante cambios de pH del medio. Entre las sustancias con carácter hidrofílico se incluyen formas funcionalizadas de nanotubos de carbono, grafeno y óxido de grafeno.[EN] The present invention relates to the use of oligoglycine tectomers as a biocompatible vehicle for transporting hydrophobic and hydrophilic substances, characterised in that the substance is incorporated into the tectomer and released therefrom by means of pH changes in the medium. The hydrophilic substances include functionalised forms of carbon nanotubes, graphene, and graphene oxide.Peer reviewedConsejo Superior de Investigaciones Científicas (España), Universidad de Zaragoza, University of SurreyB1 Patente sin examen previ
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ABSTRACT
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Carbon nanomaterials have attracted increasing attention in biomedicine recently to be used as drug nanocarriers suitable for medical treatments, due to their large surface area, high cellular internalization and preferential tumor... more
Carbon nanomaterials have attracted increasing attention in biomedicine recently to be used as drug nanocarriers suitable for medical treatments, due to their large surface area, high cellular internalization and preferential tumor accumulation, that enable these nanomaterials to transport chemotherapeutic agents preferentially to tumor sites, thereby reducing drug toxic side effects. However, there are widespread concerns on the inherent cytotoxicity of carbon nanomaterials, which remains controversial to this day, with studies demonstrating conflicting results. We investigated here in vitro toxicity of various carbon nanomaterials in human epithelial colorectal adenocarcinoma (Caco-2) cells and human breast adenocarcinoma (MCF-7) cells. Carbon nanohorns (CNH), carbon nanotubes (CNT), carbon nanoplatelets (CNP), graphene oxide (GO), reduced graphene oxide (GO) and nanodiamonds (ND) were systematically compared, using Pluronic F-127 dispersant. Cell viability after carbon nanomateri...