- Global and Comparative Sociology, Student movements, Transnational Social Movements, Ulrich Beck, Social movements in Mexico, Urban And Regional Planning, and Tourism Planning & Development, Tourism Impacts, Environmental Preservation through Tourism, Alterations in Urban Island Tourism Destinations, Crisis Management, Hellenic and International Tourism Flows, Destination Marketing, and Tourism Sustainabilityedit
ABSTRACT Background: Retroviral replication is retarded by several known host restriction factors, including APOBEC cytidine deaminases, tetherin, and TRIM5alpha. Myeloid cells support relatively low levels of viral replication, and this... more
ABSTRACT Background: Retroviral replication is retarded by several known host restriction factors, including APOBEC cytidine deaminases, tetherin, and TRIM5alpha. Myeloid cells support relatively low levels of viral replication, and this characteristic was recently attributed to the activity of the SAM-domain and HD-domain containing protein (SAMHD1). Through its phosphydrolase activity, SAMHD1 depletes the intracellular pool of free nucleotides, blocking reverse transcription. The Type II interferon, IFN gamma, reportedly stimulates ...
