Jennie Lim

Over 13% of all genes in the Arabidopsis thaliana genome encode for proteins classified as having a completely unknown function, with the function of >30% of the Arabidopsis proteome poorly characterized. Although empirical data in the form of mRNA and proteome profiling experiments suggest that many of these proteins play an important role in different biological processes, their functional characterization remains one of the major challenges in modern biology. To expand the annotation of genes with unknown function involved in the response of Arabidopsis to different environmental stress conditions, we selected 1007 such genes and tested the response of their corresponding homozygous T‐DNA insertional mutants to salinity, oxidative, osmotic, heat, cold and hypoxia stresses. Depending on the specific abiotic stresses tested, 12–31% of mutants had an altered stress‐response phenotype. Interestingly, 832 out of 1007 mutants showed tolerance or sensitivity to more than one abiotic ...

Leptospirosis is one of the common re-emerging zoonotic diseases transmitted from infected animals to humans. It is a bacterial infection caused by a species of pathogenic leptospiragenus called Spirochaetes. The very first case of human leptospirosis in Malaysia was ...