In brain-computer interface system (BCIs), direct communication between humans and computers is performed by analyzing neural signals and transforming them into digital signals. In the continuation of our previous works, in this paper, we... more
In brain-computer interface system (BCIs), direct communication between humans and computers is performed by analyzing neural signals and transforming them into digital signals. In the continuation of our previous works, in this paper, we advanced the proposed BCI system that was based on the gaze on rotating vanes. The speed of communication and convenience of the user are very important factors in BCI systems. Therefore, in this paper, for the convenience of the user, a single EEG channel was used. Also, for to increase the speed of the system, we tried to the classification of 0.5 sec epochs with a partial least squares regression (PLSR) as a fast classifier. In addition, we computed the information transfer rate (ITR) that has proved our proposed BCI system is fast and accurate. This system could be used in real-time implementations due to having high classification rate, speed and convenience of the user.
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The method of time-frequency analysis are the ways that mainly are used to analyze electroencephalography (EEG) signals. In our previous studies, we proved that watching 2D and 3D of a movie causes different effects in EEG signals. In... more
The method of time-frequency analysis are the ways that mainly are used to analyze electroencephalography (EEG) signals. In our previous studies, we proved that watching 2D and 3D of a movie causes different effects in EEG signals. In this paper, we used dataset of previous study and mean of five EEG frequency bands as features. To obtain these frequency bands, a frequency analysis and two time-frequency analysis are used. Aim of this paper is that which one of these methods can be provide better features. These methods are Fast Fourier Transform (FFT), Discrete Wavelet Transform (DWT) and Wigner-Ville Distribution (WVD). To compare these methods Partial Least Squares Regression (PLSR) as a powerful classifier was implemented. The results show that PLSR could be classified Wigner-Ville Distribution's features better than other method's features.
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Background: Striae is a common condition that is relatively difficult to treat. Recently, carboxytherapy was proposed as a treatment modality. This study aimed to evaluate the therapeutic effect of carboxytherapy in patients with striae.... more
Background: Striae is a common condition that is relatively difficult to treat. Recently, carboxytherapy was proposed as a treatment modality. This study aimed to evaluate the therapeutic effect of carboxytherapy in patients with striae. Methods: This was a pilot clinical study. Patients were treated with 10 sessions of carboxytherapy every week. The patients were photographed at the onset of the treatment course, before each treatment session, and three months after the last ones. Two dermatologists compared the images of each patient before and three months after treatment and evaluated the treatment response based on the following scores: I, no improvement (0%);II, poor (1% to 25%); III, fair (26% to 50%); IV, good (51% to 75%); and V, excellent improvement (76% to 100%). Furthermore, patients’ satisfaction with therapy outcome was recorded on a scale of 0 to 10. Results: 15 patients were enrolled in this study; 2 (13.4%) were male and 13 (86.6%) were female. Three patients (20%)...
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Objective(s): Infection with the human T-cell lymphotrophic virus type-I (HTLV-I) is endemic in Mashhad, Iran. In our research we evaluated the relation between exposure to this infection and the occurrence of dermatologic manifestations.... more
Objective(s): Infection with the human T-cell lymphotrophic virus type-I (HTLV-I) is endemic in Mashhad, Iran. In our research we evaluated the relation between exposure to this infection and the occurrence of dermatologic manifestations. Materials and Methods: 100 blood donors, who were seropositive but asymptomatic for infection with HTLV-I, were selected as case group. They were identified by the Blood Transfusion Organization Mashhad via the ELISA test and documented by PCR. Another 100 blood donors, that were seronegative for HTLV-I via the ELISA test and who were matched to the case group for age, gender, and existence of systemic diseases, were considered as the controls. Dermatologic evaluations and skin biopsies were performed if deemed necessary, and the results were statistically analyzed. Results: 73% of the case and control groups were male, while 27% in each of these groups were female. The mean age in both groups was 40.96±11.94 years. The examination indicated that 5...
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doi:10.1182/blood-2009-03-211821Prepublished online May 1, 2009;2009 113: 6528-6532€€€€Ali BazarbachiRezaee, Mojtaba Tabatabaei Yazdi, Abbas Shirdel, Hugues de The, Olivier Hermine, Reza Farid andMahmoudi, Hassan Hatoum, Hossein Rahimi,... more
doi:10.1182/blood-2009-03-211821Prepublished online May 1, 2009;2009 113: 6528-6532€€€€Ali BazarbachiRezaee, Mojtaba Tabatabaei Yazdi, Abbas Shirdel, Hugues de The, Olivier Hermine, Reza Farid andMahmoudi, Hassan Hatoum, Hossein Rahimi, Masoud Maleki, Houshang Rafatpanah, S. A. Rahim Ghada Kchour, Mahdi Tarhini, Mohamad-Mehdi Kooshyar, Hiba El Hajj, Eric Wattel, Mahmoud€
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In industry, managers must select portfolios of projects for funding, in order to advance the corporate goals. There are generally many more projects than funding can support. Ideally, managers aim to select an optimal subset of... more
In industry, managers must select portfolios of projects for funding, in order to advance the corporate goals. There are generally many more projects than funding can support. Ideally, managers aim to select an optimal subset of projects to meet the company’s goals while complying with budgetary restrictions. At the same time, they seek to control the overall risk of a portfolio of projects and ensure that cash flow or other such performance objectives are maximized. The purpose of this paper is applying a new integrated method for Portfolio Selection. Proposed approach is based on Fuzzy Prioritization Method and TOPSIS. Fuzzy Prioritization Method is used in determining the weights of the criteria by decision makers and then ranking of Portfolios are determined by TOPSIS method. In this paper a numerical example demonstrates the application of the proposed method.
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The main challenge for training in cosmetic dermatology is the difference in the attitudes of residency programs and residents about the necessity and amount of education during the residency period. A national online survey conducted... more
The main challenge for training in cosmetic dermatology is the difference in the attitudes of residency programs and residents about the necessity and amount of education during the residency period. A national online survey conducted between September 6 th and November 21 st , 2017. Residents, members of the Iranian Board of Dermatology, faculty members and program directors (PDs) were asked to participate in the survey.174 participants from 12 residency programs participated in this study and the response rate of residents, professors, and Dermatology Board Directory Members (Boardmans) and PDs was 89.8%, 61.7%, and 81.8%, respectively. Residents declared greater tendency towards practicing medical dermatology (mean score, 5.165±0.8335) over the five years after graduation than that of was perceived by professors (4.043±1.2988), and Boardmans and PDs (4.059±1.0290) ( P ˂0.001). The first residents’ priority was practicing in medical dermatology (5.165±0.8335) during 5-years after ...
Research Interests: Dermatology and Medicine
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The aim of this study is to develop a computational prediction model for implantation outcome after an embryo transfer cycle. In this study, information of 500 patients and 1360 transferred embryos, including cleavage and blastocyst... more
The aim of this study is to develop a computational prediction model for implantation outcome after an embryo transfer cycle. In this study, information of 500 patients and 1360 transferred embryos, including cleavage and blastocyst stages and fresh or frozen embryos, from April 2016 to February 2018, were collected. The dataset containing 82 attributes and a target label (indicating positive and negative implantation outcomes) was constructed. Six dominant machine learning approaches were examined based on their performance to predict embryo transfer outcomes. Also, feature selection procedures were used to identify effective predictive factors and recruited to determine the optimum number of features based on classifiers performance. The results revealed that random forest was the best classifier (accuracy = 90.40% and area under the curve = 93.74%) with optimum features based on a 10-fold cross-validation test. According to the Support Vector Machine-Feature Selection algorithm, ...
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Research Interests: Mathematics, Medicine, Algorithm, Auxin, Rootstock, and 3 moreArtificial Neural Network, Shoot, and Cytokinin
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Cutaneous leishmaniasis is an endemic disease in Iran. Unfortunately, it can lead to unsightly atrophic scars with limited treatment options. Fractional CO2 laser is accepted for treatment of atrophic acne scars and recently has been used... more
Cutaneous leishmaniasis is an endemic disease in Iran. Unfortunately, it can lead to unsightly atrophic scars with limited treatment options. Fractional CO2 laser is accepted for treatment of atrophic acne scars and recently has been used to treat cutaneous leishmaniasis, so we planned to use fractional CO2 laser on leishmaniasis scar. We conducted this study on 60 leishmaniasis scars on the face of 40 patients. The lesions were treated by a fractional CO2 laser with beam size of 120 μm, with energy of 50-90 mJ, and 50-100 spots/cm(2) density with two passes in three monthly sessions. Evaluation was done in the first and second months after the first treatment and 3 and 6 months after the last treatment. Digital photography was performed at each visit. Assessment of improvement rate by patient and physician was rated separately as follows: no improvement (0 %), mild (<25 %), moderate (25-50 %), good (51-75 %), and excellent (76-100 %). Based on patients' opinion, in the first...
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The skin is one of the important affected target organs by sulfur mustard (SM) as a chemical weapon, besides the eyes and lungs. Skin exposure with sulfur mustard results in the onset of a multiple series of events including a full set of... more
The skin is one of the important affected target organs by sulfur mustard (SM) as a chemical weapon, besides the eyes and lungs. Skin exposure with sulfur mustard results in the onset of a multiple series of events including a full set of dermal responses for normal wound healing and their mutual influence on each other, eventually leading to skin toxicity. In this process, various mediators that have a regulating role in inflammation, apoptosis, immune responses and some signaling pathways are involved. In this chapter we try to describe the current knowledge on the potential mechanisms which mediate the SM actions on skin, the clinical manifestations in the acute phase of exposure and years later (delayed or chronic ones), histopathology of SM-exposed skin and the potential therapeutic countermeasures.
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Manifestations in HTLV-I Positive Blood Donors. Iran J Basic Med Sci: 2013; Objective(s): Infection with the human T-cell lymphotrophic virus type-I (HTLV-I) is en-demic in Mashhad, Iran. In our research we evaluated the relation between... more
Manifestations in HTLV-I Positive Blood Donors. Iran J Basic Med Sci: 2013; Objective(s): Infection with the human T-cell lymphotrophic virus type-I (HTLV-I) is en-demic in Mashhad, Iran. In our research we evaluated the relation between exposure to this infection and the occurrence of dermatologic manifestations. Materials and Methods: 100 blood donors, who were seropositive but asymptomatic for infection with HTLV-I, were selected as case group. They were identified by the Blood Transfusion Organization Mashhad via the ELISA test and documented by PCR. Another 100 blood donors, that were seronegative for HTLV-I via the ELISA test and who were matched to the case group for age, gender, and existence of systemic diseases, were con-sidered as the controls. Dermatologic evaluations and skin biopsies were performed if deemed necessary, and the results were statistically analyzed. Results: 73% of the case and control groups were male, while 27% in each of these groups were female. The m...
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Introduction and Objectives: However mycetoma is the most common disease among sub-cutaneous mycotic infections, but it is a rare sporadic infection. The aim of this study is to investigate the clinical presentation, etiologic agents,... more
Introduction and Objectives: However mycetoma is the most common disease among sub-cutaneous mycotic infections, but it is a rare sporadic infection. The aim of this study is to investigate the clinical presentation, etiologic agents, epidemiologic factor and the result of treatment among 16 patients admitted at university hospitals of Mashhad. Materials and Methods: During 30 years (1982-2012) a total of 23 patients with deep skin lesions were introduced to Department of Mycology, Ghaem and Emam Reza hospitals, Mashhad Iran. Of those the result of direct examination and culture of 16 patients approved for mycetoma. Demographic clinical and Lab. data of the patients obtained for analysis. Results: Among 23 individual referred to mycology labs, the result of direct examination and culture of 16 patients approved for mycetoma. Of these, 13 individuals (81.25%) were male and 3 (18. 75) were female. Most of them were more than 40 years old. 56% of the patients were farmer. Except one dr...
ABSTRACT Background: Pemphigus is a group of autoimmune blistering skin diseases that is related to auto antibodies against desmoglein 1 and 3. Many reports have shown that HSV1, HSV2, VZV, EBV, CMV, HHV8, and HIV are triggering agents... more
ABSTRACT Background: Pemphigus is a group of autoimmune blistering skin diseases that is related to auto antibodies against desmoglein 1 and 3. Many reports have shown that HSV1, HSV2, VZV, EBV, CMV, HHV8, and HIV are triggering agents for the activation and exacerbation of pemphigus. In this study, we decided to evaluate the frequency of HSV1, HSV2, HHV8, and EBV in paraffin-embedded specimens of the new cases of pemphigus patients using immunohistochemical methods. Method: Thirty patients with pemphigus whose diagnosis was proved with direct immunofluorescens studies (20 cases of pemphigus vulgaris and 10 cases of pemphigus foliaceus) and 10 specimens from the free margins of excised melanocytic nevi were collected. Immunohistochemical staining was performed for HSV1 and EBV (using Novo Castra kit) and for HSV2 and HHV8 (using Dako kit). Result: The results showed a significance difference in the frequency of positive staining for HSV1 in skin lesions of pemphigus vulgaris, foliaceus, and controls (P= 0.041), foliaceus group more positive staining than vulgaris group and both more than controls, but not for HSV2, EBV, and HHV8 markers. Positive staining for HHV8 occurred in 30% of PF patients and 15% of PV patients but P value was not significant (0.171). Conclusion: Like previous studies, our research also indicated significant prevalence of HSV1 in lesions of pemphigus patients, especially in pemphigus foliaceus. We collected new cases of pemphigus before starting immunosuppressive therapy, so we think that the presence of HSV1 in skin lesions of patients can act as a triggering factor for the disease which could not be attributed to the suppressive therapy.
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Research Interests: Dermatology, Medicine, Iran, Humans, Chemical Warfare Agents, and 15 moreFemale, Male, Skin, Clinical Sciences, Aged, Middle Aged, Immune system, Adult, Public health systems and services research, Hyperpigmentation, Mustard Gas, Hematocrit, Immunoglobulins, Skin Biopsy, and Severity of Illness Index
Research Interests: Biology, Cell Biology, Cytotoxicity, Stem Cell, Apoptosis, and 15 moreMedicine, Signal Transduction, Caspases, Cell Differentiation, Humans, Mesenchymal Stem Cell, Retinoic Acid, Primary Cell Culture, Tretinoin, Umbilical Cord, Mesenchymal Stromal Cells, Cytotoxins, Biochemistry and cell biology, Gene Expression Regulation, and Cell count
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Cutaneous leishmaniasis is an endemic disease in developing countries caused by different species of leishmania parasite, and if left untreated, it will result in a deformed scar after a relatively long period. Although various systemic... more
Cutaneous leishmaniasis is an endemic disease in developing countries caused by different species of leishmania parasite, and if left untreated, it will result in a deformed scar after a relatively long period. Although various systemic and topical treatments have been proposed for leishmaniasis, pentavalent Antimony compounds remain the first-line treatment for it. Considering the cases with treatment failure, potential side effects and reluctance of patients to receive the drug, there are continuing efforts to find better treatment alternatives. Comparison of the effect of intralesional 2% zinc sulfate injection with Glucantime in treatment of acute cutaneous leishmaniasis. In this clinical trial, 45 patients with clinical diagnosis of cutaneous leishmaniasis and positive direct smear for leishman body were treated by intralesional injection of either 2% zinc sulfate or Glucantime. After simple randomization, in one group the patients were treated with 2 bouts of intralesional 2% zinc sulfate with a 2-week interval, and in the other group they were treated with 6 weekly bouts of intralesional Glucantime. The patients were monitored in two week intervals for 8 weeks. Healing of the lesions was evaluated clinically and by direct smear, and the data were analyzed using SPSS (11.5) software, t-Student, Mann-Whitney and Analysis of covariance (ANCOVA) statistical tests. In the end of study, 34 patients completed the study, 10 of whom received intralesional Glucantime and 24 of whom received intralesional 2% zinc sulfate. The healing rate after 8 weeks was 80% in the group receiving intralesional Glucantime and 33.3% in the one receiving 2% zinc sulfate (P=0.009). Based on the results of this study, intralesional injection of 2% zinc sulfate was less effective in treatment of cutaneous leishmaniasis than intralesional Glucantime.
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Development of skin neoplasms is one of the most important chronic complications of radiation therapy. Basal cell carcinoma (BCC) is the most frequent carcinoma occurring at the region of the body to which radiotherapy was delivered. The... more
Development of skin neoplasms is one of the most important chronic complications of radiation therapy. Basal cell carcinoma (BCC) is the most frequent carcinoma occurring at the region of the body to which radiotherapy was delivered. The aim of this study was to evaluate clinical and histological aspects of basal cell carcinoma in patients with a history of radiotherapy. Medical records and microscopic slides of 80 patients with basal cell carcinoma who had received radiotherapy (1996-2006) were reviewed in pathology department of Imam Reza hospital of Mashhad, Iran. Collected data were analyzed statistically using descriptive test. 60 men and 20 women were included, majority of them in their sixties. Plaque was the most common clinical pattern of basal cell carcinoma. Fifty one percent of the patients had pigmented and 42.5% had multiple lesions. Scalp was the most common site of involvement. Histologically, macronodular and pigmented carcinoma were the most predominant forms of basal cell carcinoma. Majority of patients had scalp involvement and multiple lesions. Nodular and pigmented forms were the most common histological findings. We suggest the need for close supervision in patients with a history of radio therapy in the past.
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Acute hemorrhagic edema of infancy (AHEI) is a selflimited leukocytoclastic small vessel vasculitis involving small blood vessels in the dermis. It typically occurs in infants and young children up to 24 months of age. The most striking... more
Acute hemorrhagic edema of infancy (AHEI) is a selflimited leukocytoclastic small vessel vasculitis involving small blood vessels in the dermis. It typically occurs in infants and young children up to 24 months of age. The most striking classic feature of this disease is the contrast between the acuteness of the cutaneous lesion and the good general state of the patient. The disorder was believed to be a variant of Henoch–Schönlein purpura (HSP) but now is considered to be a distinct entity because of lack of visceral involvement and less frequent occurrence of IgA skin deposition. We report the case of a 16-month-old girl with acute hemorrhagic edema.