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Meo Meo

    Meo Meo

    K-FLOW is a project co-funded by the European Commission, in the GROWTH Programme, whose aim is to develop a Software platform and a set of supporting methodologies for managing knowledge in an Extended Manufacturing Enterprise (EME).... more
    K-FLOW is a project co-funded by the European Commission, in the GROWTH Programme, whose aim is to develop a Software platform and a set of supporting methodologies for managing knowledge in an Extended Manufacturing Enterprise (EME). Principal elements considered in an EME are: plant production stations, design office stations, customers and suppliers. The main objective is to provide to workers of the EME, the right knowledge, at the right place, in the right form, at the right time. The expected benefits for the EME are: to earn competitiveness, to improve production, productivity and quality rates, service, and reduce costs, lead time and time to market by co-ordinating activities amongst different actors that improve the overall performance of the EME. The societal objectives are: to improve the working conditions, quality of work and workers’ skills, and reduce the environmental impact of the production processes.
    Research Interests:
    Assessing urine mutagenicity with the Salmonella mutagenicity test is often limited by the volumes of the samples. Optimization of the assay was performed with factorial and Doehlert designs. Two fractional factorial designs 2(3-1) (3... more
    Assessing urine mutagenicity with the Salmonella mutagenicity test is often limited by the volumes of the samples. Optimization of the assay was performed with factorial and Doehlert designs. Two fractional factorial designs 2(3-1) (3 factors, 4 experiments) were used to estimate the main effects of the percent S9 in the mix, the time of liquid incubation, the inoculum size and the growth conditions. A Doehlert design (3 factors, 13 experiments) was used to study the main effects and the interactions of the NADP, G6P and S9 in the mix. The positive markers were benzo[a]pyrene (BaP, 0.3 microgram/plate) and a pool of smokers' urine (SU, 1.25 ml equivalent/plate). The response was limited to the induction factor (IF, number of induced revertants/number of spontaneous revertants) with Salmonella typhimurium TA98. The optimal conditions for BaP were: a 60 min period of liquid incubation and a volume of 0.1 ml (approx. 10(8) cells/plate) of an overnight culture grown in 50 ml of Nutrient Broth No. 2 from a 250 ml flask. The S9 mix (0.1 ml, final volume) included 1.5% of S9, 1.0 mM NADP and 4.4 mM G6P. The maximal IF was 15.79. The optimal conditions for SU were: a 60 min period of liquid incubation and a volume of 0.1 ml (approx. 10(8) cells/plate) of an overnight culture grown in 7 ml of Nutrient Broth No. 2 from a 20 x 180 mm tube. The S9 mix (0.1 ml, final volume) included: 4% S9, 4.2 mM NADP and 5.2 mM G6P. The maximal IF was 10.95. These optimal conditions did not modify the spontaneous frequencies of the tester strains: TA97a, TA98, TA100 and TA102. The dose-response curves of mutagenic urine samples were found to be non-linear. This micromethod required 8-fold less urine sample and 12.5-fold less liver homogenate as compared to the standard plate incorporation assay and was from 6.2- to 11.8-fold more sensitive to evaluate urine mutagenicity. The sensitivity of this technique was found to be limited to individuals smoking more than approx. 5 cigarettes/day by the standard extraction-concentration procedure.
    ABSTRACT Recent research on game-theoretic approaches for non-cooperative resource allocation in relay-assisted interference channels is reviewed in this paper. The considered utility function is the physical layer energy efficiency,... more
    ABSTRACT Recent research on game-theoretic approaches for non-cooperative resource allocation in relay-assisted interference channels is reviewed in this paper. The considered utility function is the physical layer energy efficiency, which is measured in bit/J, and denotes the number of bits successfully delivered to the receiver for each energy unit drained from the battery. Both the cases in which the power dissipated in the transmitter circuit is included and not included in the utility functions are considered, and, also, the case in which there is a direct path between transmitters and receivers is briefly addressed. Analytic results on the existence of Nash equilibrium points are given, and extensive numerical results provide insight on the performance of the reviewed resource allocation algorithms.
    ... Claudio Casetti, Carla-Fabiana Chiasserini, Roberta Fracchia, Michela Meo Dipartimento di Elettronica, Politecnico di Torino Email: name.lastname@polito.it ... AISLE optimally determines the wireless interface to be used for data... more
    ... Claudio Casetti, Carla-Fabiana Chiasserini, Roberta Fracchia, Michela Meo Dipartimento di Elettronica, Politecnico di Torino Email: name.lastname@polito.it ... AISLE optimally determines the wireless interface to be used for data transfer, by con-stantly monitoring the available ...
    Analytical approaches for the performance investigation of portions of the Internet often consider the behavior of TCP over congested (or bottleneck) links. In several cases, the analysis is based on an iterative fixed point approximation... more
    Analytical approaches for the performance investigation of portions of the Internet often consider the behavior of TCP over congested (or bottleneck) links. In several cases, the analysis is based on an iterative fixed point approximation (FPA) to compute the equilibrium point, in terms of packet loss rate and offered load, that represents the operating point of the network. Almost invariably, the FPA is conjectured to converge, but no proof of convergence is provided. This paper proves that a general model of a reliable protocol (such as TCP) over congested links converges to a unique stable solution under mild regularity conditions. This provides a justification of the convergence observed in the literature and a solid base for the further development of analytical approaches based on FPAs.
    Research Interests:
    The threat of global climate change caused by fossil fuel use and industrial activities is both unique and ubiquitous. Characterized by uncertainty, irreversibility, and pervasiveness, an atmospheric warming of several degrees over the... more
    The threat of global climate change caused by fossil fuel use and industrial activities is both unique and ubiquitous. Characterized by uncertainty, irreversibility, and pervasiveness, an atmospheric warming of several degrees over the next century presents a substantial public policy challenge to craft effective and timely responses to an array of potential environmental impacts, of which one of the most serious is accelerated sea level rise (National Research Council, 1983; Schneider, 1989). Yet how well society can cope with changing climate and a rising Ocean is unclear. No historical precedent of a world undergoing change as rapidly or as dramatically exists, let alone one which can provide some reference for policy analysis or planning (Schelling, 1983; Lave, 1988). Societal responses to an unparalleled rise in sea level of up to a meter in the next century may take a variety of forms. Depending upon the timing and speed with which the Ocean rises, affected coastal communities may opt to defend their shoreline with structural and nonstructural measures or relocate landward at a pace that enables socioeconomic activities sufficient time to adapt to rising waters (National Research Council, 1987). Other less developed or less affluent regions may have to be abandoned. Developing acceptable policies for mitigating the risks associated with sea level rise requires credible predictions, an assessment of the specific climate change impacts likely to accrue, and a knowledge of actions that could be taken to reduce or minimize potential impacts. In support of such efforts, information about the way in which sea level rise impacts affect, and in turn are affected by, social institutions can help gauge the feasibility of individual strategies.
    Thirteen saponins were isolated and identified from Calendula officinalis, C. arvensis and Hedera helix. Mutagenic and antimutagenic activities of these products were investigated using a modified liquid incubation technique of the... more
    Thirteen saponins were isolated and identified from Calendula officinalis, C. arvensis and Hedera helix. Mutagenic and antimutagenic activities of these products were investigated using a modified liquid incubation technique of the Salmonella/microsomal assay. The Salmonella tester strain TA98 +/- S9 mix was used. Screening of the antimutagenic activity was performed with a known promutagen: benzo-[a]pyrene (BaP) and a mutagenic urine concentrate from a smoker (SU). Antimutagenic activities were also compared with the activity of chlorophyllin. All the saponins were found to be non-toxic and non-mutagenic for doses of 400 micrograms. Chlorophyllin inhibited the mutagenic activities of BaP (1 microgram) and SU (5 microliters) in a dose-dependent manner. The four saponins from C. arvensis and the three saponins from H. helix showed antimutagenic activity against BaP (1 microgram) and SU (5 microliters) with a dose-response relationship. The possible mechanism of the antimutagenic activity of saponins is discussed.
    ABSTRACT One of the major concerns related to flight safety is the impact of birds. To minimize the risks, there is I lie need to improve impact resistance of aircraft by developing high-performance materials and better structural design... more
    ABSTRACT One of the major concerns related to flight safety is the impact of birds. To minimize the risks, there is I lie need to improve impact resistance of aircraft by developing high-performance materials and better structural design of aircraft structures. Because of their remarkable impact properties. fiber metal laminates with layers of aluminum alloy and high-strength glass-fiber composite are potential candidate materials to he employed for aircraft structures susceptible to bird strikes. This paper describes an experimental and numerical campaign aimed at assessing the bird strike resistance of a fiber-metal-laminate-composite leading edge for the wing of a transport aircraft. Three different fiber-metal-laminate were designed using advanced finite element simulations. they were manufactures and finally tested to analyze their impact-energy-absorbing capabilities. The finite element models were developed, adopting a Lagrangian approach in such a way to be able to correctly simulate impacts with large deformations and perforations of the structures and to characterize the different inelastic/brittle behaviors and failure modes of the fiber metal laminates. The numerical simulations were generally in good agreement with the experimental values, demonstrating the robustness of the developed finite element simulations in supporting the design of bird-strike-resistant aircraft structures.
    In this paper, we outline a methodology that can be applied to model the behavior of TCP Reno flows. The proposed methodology stems from a Markovian model of a single TCP source, and eventually considers the superposition and interaction... more
    In this paper, we outline a methodology that can be applied to model the behavior of TCP Reno flows. The proposed methodology stems from a Markovian model of a single TCP source, and eventually considers the superposition and interaction of several such sources using standard queueing analysis techniques. Our approach allows the evaluation of such performance indices as throughput, queueing
    Abstract The paper investigates experimentally and numerically the response of a smart hybrid thermoplastic composite plate subjected to low-velocity impact. The response of the composite plates embedded with shape memory alloy (SMA)... more
    Abstract The paper investigates experimentally and numerically the response of a smart hybrid thermoplastic composite plate subjected to low-velocity impact. The response of the composite plates embedded with shape memory alloy (SMA) wires embedded is investigated. The SMA wires were embedded within a fabric layer of the composite laminate placed in the middle plane of the laminate. By embedding SMA wires into composites an increase of the damage resistance and ductility of composites structures was observed ...
    Several studies have shown in humans an association between renal carcinoma and cigarette smoking. Cigarette smoke contains numerous cytochrome P450 inducers and substrates. In the present study we investigated the effect of cigarette... more
    Several studies have shown in humans an association between renal carcinoma and cigarette smoking. Cigarette smoke contains numerous cytochrome P450 inducers and substrates. In the present study we investigated the effect of cigarette smoke on the regulation of murine cytochrome P450 expression in kidney and its possible role in the induction of single strand breaks in DNA. Results demonstrated that CYP2E1 (activity, protein, and MRNA) was induced by tobacco smoke (2.1, 5.6 and 20.8, respectively). We did not detect any CYP1A, CYP2B, and CYP3A using Western blot and RT-PCR experiments. We have analyzed the renal single strand breaks of DNA in control and treated mice. The results indicated an increase of single strand breaks of DNA in kidney from treated mice which paralleled the high inducibility of the CYP2E1. No significant difference was observed between lymphocytes (which expressed very low or undetectable cytochrome P450 levels) of control and treated mice.
    Constraint Handling Rules (CHR) is a committed-choice declarative language which has been designed for writing constraint solvers. A CHR program consists of multiheaded guarded rules which allow to rewrite constraints into simpler ones... more
    Constraint Handling Rules (CHR) is a committed-choice declarative language which has been designed for writing constraint solvers. A CHR program consists of multiheaded guarded rules which allow to rewrite constraints into simpler ones until a solved form is reached. CHR has received considerable attention, both from the practical and from the theoretical side. Nevertheless, due the use of multiheaded clauses, there are several aspects of the CHR semantics which have not been clarified yet. In particular, no compositional semantics for CHR has been defined so far. In this article we introduce a fix-point semantics which characterizes the input/output behavior of a CHR program and which is and-compositional, that is, which allows to retrieve the semantics of a conjunctive query from the semantics of its components. Such a semantics can be used as a basis to define incremental and modular analysis and verification tools.