1,063 Result(s)
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Article
Discrimination between HER2-overexpressing, -low-expressing, and -zero-expressing statuses in breast cancer using multiparametric MRI-based radiomics
To explore the performance of multiparametric MRI-based radiomics in discriminating different human epidermal growth factor receptor 2 (HER2) expressing statuses (i.e., HER2-overexpressing, HER2-low-expressing...
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Article
New Criterions on Nonexistence of Periodic Orbits of Planar Dynamical Systems and Their Applications
Characterizing existence or not of periodic orbit is a classical problem, and it has both theoretical importance and many real applications. Here, several new criterions on nonexistence of periodic orbits of t...
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Article
Optimizing mobility resource allocation in multiple MaaS subscription frameworks: a group method of data handling-driven self-adaptive harmony search algorithm
Mobility as a Service (MaaS) transforms urban transportation from car ownership to subscription-based models. A key factor for the success of MaaS is accurately predicting users’ Willingness to Pay (WTP) for v...
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Article
Open AccessSimulation of CRISPR-Cas9 editing on evolving barcode and accuracy of lineage tracing
We designed a simulation program that mimics the CRISPR-Cas9 editing on evolving barcode and double strand break repair procedure along with cell divisions. Emerging barcode mutations tend to build upon previo...
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Article
Open AccessLow temperature exposure influences nitrogen metabolism resulting in decreased Cry1Ac insecticidal endotoxin content in cotton seeds
Sudden temperature drops, resulting from extreme weather events, often occur during the boll-setting period of cotton in Xinjiang, China, causing decreased expression of Bacillus thuringiensis (Bt) insecticidal p...
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Article
Remote site-selective arene C–H functionalization enabled by N-heterocyclic carbene organocatalysis
Catalytic site-selective functionalization of distal C–H bonds represents a formidable challenge in organic synthesis. Particularly, the precise functionalization of distal aromatic C(sp2)–H bonds remains largely...
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Article
A Clinical Analysis of Prognosis and Patient-Reported Outcomes of Oncoplastic Breast-Conserving Surgery for Early Breast Cancer: A Retrospective Cohort Study
Approximately 25–30% of patients suffer from breast deformity and/or asymmetry after conventional breast-conserving surgery (CBCS). Generally, it is thought that oncoplastic breast-conserving surgery (OBCS) re...
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Article
Risk factors of missed early gastric cancer in endoscopic resected population: a retrospective, case–control study
Missed early gastric cancer (MEGC) is prevalent during esophagogastroduodenoscopy (EGD), which is the first-line recommended strategy for detecting early gastric cancer (EGC). Hence, we explored the risk facto...
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Article
Machine learning prediction models for in-hospital postoperative functional outcome after moderate-to-severe traumatic brain injury
This study aims to utilize machine learning (ML) and logistic regression (LR) models to predict surgical outcomes among patients with traumatic brain injury (TBI) based on admission examination, assisting in m...
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Article
Identification of dense nonaqueous phase liquid sources in groundwater: a review of isotope technique
Excessive dense nonaqueous phase liquids (DNAPLs) in subsurface aquifers posed a threat to human health and sustainable development of groundwater resources. Accurately identifying the sources of DNAPLs is cru...
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Article
Somatic and germline aberrations in homologous recombination repair genes among Chinese high-risk breast cancer patients by multi-gene next-generation sequencing
Recently, genes involved in homologous recombination repair (HRR) pathway have been extensively studied. However, the landscapes of HRR gene mutations remain poorly defined in Chinese high-risk breast cancer (...
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Article
Open AccessClinical and genetic features in autosomal recessive bestrophinopathy in Chinese cohort
To provide a genotype and phenotype characterization of the BEST1 mutation in Chinese patients with autosomal recessive bestrophinopathy (ARB) through multimodal imaging and next-generation sequencing (NGS).
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Article
Hydrodynamics-based assessment of flood losses in an urban district under changing environments
In order to accurately assess the urban flood losses under changing environments, a flood losses assessment framework has been proposed based on a bidirectional coupled 1D/2D hydrodynamic model. Using the prop...
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Article
The effect of coffee consumption on three main bone disorders: a Mendelian randomization trial
Despite a large number of observational studies examining the effect of coffee consumption(CC) on bone disorders(BDs), particularly, osteoarthritis(OA), osteoportic fracture(OF), and rheumatoid arthritis(RA), ...
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Article
Interval Sensitivity Analysis and Optimization of Magneto-Rheological Damper with Energy Harvesting Characteristics
In order to overcome the limitation of external power supply and complex maintenance of Magneto-Rheological (MR) damper, the MR damper with energy harvesting characteristics is proposed. The output damping for...
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Article
Busulfan plus cyclophosphamide vs. total body irradiation plus cyclophosphamide for allogeneic hematopoietic stem cell transplantation in patients with acute T lymphoblastic leukemia: a large-scale propensity score matching-based study
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Article
A cross-level analysis about the impact of pandemic-related stressors, online learning satisfaction and coping on elementary school students’ psychological symptoms
This study was aimed to explore the influence of COVID-19 pandemic on elementary school students from cross-level perspective. With a cross-section survey, 823 elementary school students (Mage = 11.89, SD = 1.30)...
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Article
Assessment of agricultural drought status using visible infrared imaging radiometer suite land products
The Moderate Solution Imaging Spectroradiometer (MODIS) is a multispectral sensor that has been actively researched in various fields using diverse land and atmospheric products. MODIS was first launched over ...
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Article
Hypoxia exerts greater impacts on shallow groundwater nitrogen cycling than seawater mixture in coastal zone
There is no doubt that hypoxia and seawater mixture are profoundly affecting the global nitrogen (N) cycle. However, their mechanisms for altering N cycling patterns in shallow coastal groundwater are largely ...
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Article
Open AccessGestational exposure to environmental chemicals and epigenetic alterations in the placenta and cord blood mononuclear cells
Exposure to environmental chemicals such as phthalates, phenols, and polycyclic aromatic hydrocarbons (PAHs) during pregnancy can increase the risk of adverse newborn outcomes. We explored the associations bet...