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1,033 Result(s)
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Article
Risk factors of missed early gastric cancer in endoscopic resected population: a retrospective, case–control study
Missed early gastric cancer (MEGC) is prevalent during esophagogastroduodenoscopy (EGD), which is the first-line recommended strategy for detecting early gastric cancer (EGC). Hence, we explored the risk facto...
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Giant piezotronic effect in ferroelectric field effect transistor
The piezotronics effect utilizes a piezopotential to modulate and control current in piezo-semiconductors. Ferroelectric materials, as a type of piezoelectric materials, possess piezoelectric coefficients that...
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Somatic and germline aberrations in homologous recombination repair genes among Chinese high-risk breast cancer patients by multi-gene next-generation sequencing
Recently, genes involved in homologous recombination repair (HRR) pathway have been extensively studied. However, the landscapes of HRR gene mutations remain poorly defined in Chinese high-risk breast cancer (...
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Open AccessClinical and genetic features in autosomal recessive bestrophinopathy in Chinese cohort
To provide a genotype and phenotype characterization of the BEST1 mutation in Chinese patients with autosomal recessive bestrophinopathy (ARB) through multimodal imaging and next-generation sequencing (NGS).
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Hydrodynamics-based assessment of flood losses in an urban district under changing environments
In order to accurately assess the urban flood losses under changing environments, a flood losses assessment framework has been proposed based on a bidirectional coupled 1D/2D hydrodynamic model. Using the prop...
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An evolved artificial radical cyclase enables the construction of bicyclic terpenoid scaffolds via an H-atom transfer pathway
While natural terpenoid cyclases generate complex terpenoid structures via cationic mechanisms, alternative radical cyclization pathways are underexplored. The metal-catalysed H-atom transfer reaction (M-HAT) ...
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Remote site-selective arene C–H functionalization enabled by N-heterocyclic carbene organocatalysis
Catalytic site-selective functionalization of distal C–H bonds represents a formidable challenge in organic synthesis. Particularly, the precise functionalization of distal aromatic C(sp2)–H bonds remains largely...
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The effect of coffee consumption on three main bone disorders: a Mendelian randomization trial
Despite a large number of observational studies examining the effect of coffee consumption(CC) on bone disorders(BDs), particularly, osteoarthritis(OA), osteoportic fracture(OF), and rheumatoid arthritis(RA), ...
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Interval Sensitivity Analysis and Optimization of Magneto-Rheological Damper with Energy Harvesting Characteristics
In order to overcome the limitation of external power supply and complex maintenance of Magneto-Rheological (MR) damper, the MR damper with energy harvesting characteristics is proposed. The output damping for...
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Busulfan plus cyclophosphamide vs. total body irradiation plus cyclophosphamide for allogeneic hematopoietic stem cell transplantation in patients with acute T lymphoblastic leukemia: a large-scale propensity score matching-based study
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Hypoxia exerts greater impacts on shallow groundwater nitrogen cycling than seawater mixture in coastal zone
There is no doubt that hypoxia and seawater mixture are profoundly affecting the global nitrogen (N) cycle. However, their mechanisms for altering N cycling patterns in shallow coastal groundwater are largely ...
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Open AccessGestational exposure to environmental chemicals and epigenetic alterations in the placenta and cord blood mononuclear cells
Exposure to environmental chemicals such as phthalates, phenols, and polycyclic aromatic hydrocarbons (PAHs) during pregnancy can increase the risk of adverse newborn outcomes. We explored the associations bet...
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Open AccessSafety of propofol-assisted deep extubation in the dental treatment of children—a retrospective, observational study
Awake extubation and deep extubation are commonly used anesthesia techniques. In this study, the safety of propofol-assisted deep extubation in the dental treatment of children was assessed.
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Open AccessA morphological traits dataset of Heteroptera sampled in biodiversity priority areas of Southwest China
Functional traits reveal the adaptive strategies of species to their environment, and are relevant to the formation of communities, the function of ecosystems, and the mechanisms underlying biodiversity. Howev...
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Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms
Smc5/6 is a member of the eukaryotic structural maintenance of chromosomes (SMC) family of complexes with important roles in genome maintenance and viral restriction. However, limited structural understanding ...
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Open AccessEmerging trends in sperm selection: enhancing success rates in assisted reproduction
This comprehensive review explores the evolving landscape of sperm selection techniques within the realm of Assisted Reproductive Technology (ART). Our analysis delves into a range of methods from traditional ...
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Assessing water distribution and efficiency by coupled hydraulic-hydrological modeling for irrigation canal network
In South Korea, performance of irrigation systems can be improved through hardware changes, such as canal linings and the installation of control structures, as well as through operational improvements, such a...
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Dermoscopic features of melanocyte-derived tumors in mucosal sites: a case control study
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Assessment of agricultural drought status using visible infrared imaging radiometer suite land products
The Moderate Solution Imaging Spectroradiometer (MODIS) is a multispectral sensor that has been actively researched in various fields using diverse land and atmospheric products. MODIS was first launched over ...
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Open AccessNitrogen addition has divergent effects on phosphorus fractions in four types of soils
Globally increasing atmospheric nitrogen (N) deposition has altered soil phosphorus (P) transformations and availability, and thereby influenced structure and function of terrestrial ecosystems. Edaphic charac...