To investigate (i) the differential changes in premenstrual symptoms, mood, cognitions, and coping strategies during two treatments [cognitive-behavioural therapy (CBT) and fluoxetine] for premenstrual dysphoric disorder (PMDD) and (ii)... more
To investigate (i) the differential changes in premenstrual symptoms, mood, cognitions, and coping strategies during two treatments [cognitive-behavioural therapy (CBT) and fluoxetine] for premenstrual dysphoric disorder (PMDD) and (ii) the characteristics of those with good vs. poor outcome post treatment and at 1 year follow-up. Premenstrual symptoms, mood (Hospital Anxiety and Depression Scale, HADS), causal attributions, and use of cognitive and behavioural coping strategies were examined during 6 months of both treatments. The two treatment groups were then combined and divided on the basis of good vs. poor outcome posttreatment and at 1 year follow-up. Baseline measures were used to predict posttreatment outcome, and baseline and posttreatment measures were examined when attempting to predict outcome at 1 year follow-up. Both treatments were equally effective at the end of 6 months (prospective daily diary measure). Fluoxetine treatment had a more rapid effect and greater impa...
Objective: To compare the emotional state during the first 3 days after coronary artery surgery of patients who had undergone early versus conventional extubation. Design: A prospective, randomized, controlled trial. Setting: University... more
Objective: To compare the emotional state during the first 3 days after coronary artery surgery of patients who had undergone early versus conventional extubation. Design: A prospective, randomized, controlled trial. Setting: University hospital, single center. Participants: Eligible patients (n= 100) presenting for elective coronary artery surgery, randomized to an early extubation group or a conventional extubation group. Interventions: Emotional status was measured by the Hospital Anxiety and Depression Scale (HAD), the ...
Background/Aims: Neurodegenerative disorders (ND) have a major impact on quality of life (QoL) and place a substantial burden on patients, their families and carers; they are the second leading cause of disability. The objective of this... more
Background/Aims: Neurodegenerative disorders (ND) have a major impact on quality of life (QoL) and place a substantial burden on patients, their families and carers; they are the second leading cause of disability. The objective of this study was to examine QoL in persons ...
Objective: To review the literature of the validity of the Hospital Anxiety and Depression Scale (HADS). Method: A review of the 747 identified papers that used HADS was performed to address the following questions: (I) How are the factor... more
Objective: To review the literature of the validity of the Hospital Anxiety and Depression Scale (HADS). Method: A review of the 747 identified papers that used HADS was performed to address the following questions: (I) How are the factor structure, discriminant validity and the internal consistency of HADS? (II) How does HADS perform as a case finder for anxiety disorders
Background The objectives of this pilot study were to evaluate the safety and efficacy of the central nervous system stimulant methylphenidate in the management of asthenia in breast cancer patients treated with docetaxel. Patients and... more
Background The objectives of this pilot study were to evaluate the safety and efficacy of the central nervous system stimulant methylphenidate in the management of asthenia in breast cancer patients treated with docetaxel. Patients and methods Patients with early breast cancer who presented asthenia >3 on the Visual Analogue Scale (VAS) after the first cycle of docetaxel-based chemotherapy were included. Patients received two additional cycles of chemotherapy, one with methylphenidate (10 mg bid) and the other without methylphenidate. Asthenia was evaluated using VAS and the Functional Assessment of Cancer Therapy-Fatigue (FACT-F) scale. Distress was assessed using the Hospital Anxiety and Depression Scale (HADS), and quality of life using FACT-F. Results Ten patients were included and evaluated for efficacy and safety. Overall, cycles with methylphenidate were better tolerated than those without methylphenidate in terms of asthenia (VAS, p = 0.004; FACT-F, p = 0.027) and quality of life (FACT-F, p = 0.047). No significant differences were observed in terms of distress (HADS, p = 0.297). Six (60%) patients continued with methylphenidate after study end. Main adverse events during study were palpitations and insomnia (30% of patients each). Conclusions This pilot study suggests that methylphenidate may reduce asthenia and improve quality of life in breast cancer patients treated with docetaxel.
Objective: The frequency and impact of pain and depression have been long underestimated in Multiple Sclerosis (MS) patients. Therefore, systematic screening and management of pain and depression are recommended for these patients. The... more
Objective: The frequency and impact of pain and depression have been long underestimated in Multiple Sclerosis (MS) patients. Therefore, systematic screening and management of pain and depression are recommended for these patients. The current study evaluated the effectiveness of Mindfulness-Based Therapy (MBT) in reducing pain and depression in patients with MS. Methods: This was a quasi-experimental study with a pre-test, post-test and a control group design. We conducted a randomized trial on 24 MS patients with primary pain and depression. Moreover, they were members of the MS Society at Shahid Sadooghi Hospital in Yazd City, Iran, in 2017. The study participants were randomly divided into the test (n=12) and control (n=12) groups. The study participants were evaluated at 3-time points (baseline, end of the treatment, follow-up) using the McGill Pain Questionnaire and Depression subscale of the Hospital Anxiety and Depression Scale (HADS) as outcome measures. Results: The repeated measures Analyses of Variance (ANOVA) results revealed that MBT significantly reduced pain and depression in MS patients compared to the controls (P<0. 05). The effect of outcome measures was maintained at 2-months follow-up (P<0.05). The effect size on pain and depression were 0.41 and 0.43, respectively. Conclusion: MBT has been effective on pain and depression reduction among MS patients.
RESUMEN Todo instrumento de valoración psiquiátrica precisa de estudios que describan sus características y analicen su validez en contextos diferentes al de su creación. El Hospital Anxiety and Depression Scale fue diseñado para la... more
RESUMEN Todo instrumento de valoración psiquiátrica precisa de estudios que describan sus características y analicen su validez en contextos diferentes al de su creación. El Hospital Anxiety and Depression Scale fue diseñado para la detección de trastornos afectivos en el ámbito del Hospital General. En el presente estudio sobre pacientes con diagnósticos pertenecientes a las categorías F3 y F4 de la CIE-10 en una Unidad de Salud Mental Comunitaria el HADS parece mostrarse como un instrumento válido y consistente. SUMMARY All measuring instruments require further validation and descriptive studies in other fields different from they were designed. The Hospital Anxiety and Depression Scale was designed for detection and assessment of mood disorders in the setting of Hospital and Surgical Clinics. In the present study, patients with F3 and F4 ICD-10 category diagnoses in a Community Mental Health Unit were rated. The results indicate a good validity and high internal consistency of the instrument.
Symptoms of heartburn has an impact on health-related quality of life (HRQL). When a questionnaire is translated into a new language, a linguistic validation is necessary but not sufficient unless the psychometric characteristics have... more
Symptoms of heartburn has an impact on health-related quality of life (HRQL). When a questionnaire is translated into a new language, a linguistic validation is necessary but not sufficient unless the psychometric characteristics have been verified. The aim is to document the psychometric characteristics of the German translation of the Gastrointestinal Symptom Rating Scale (GSRS) and Quality of Life in Reflux and Dyspepsia (QOLRAD) questionnaire. 142 patients with symptoms of heartburn (Age: M = 47.5, +/- 14.6; Males = 44.4%) completed the German translation of GSRS, the QOLRAD, the Short-Form-36 (SF-36) and the Hospital Anxiety and Depression (HAD) scale. The internal consistency reliability of GSRS ranged from 0.53-0.91 and of QOLRAD from 0.90-0.94, respectively. The test-retest reliability of GSRS ranged from 0.49-0.73 and of QOLRAD from 0.70-0.84. The relevant domains of the GSRS and QOLRAD domain scores significantly correlated. GSRS domains of Abdominal Pain and Constipation ...
In general the Iranian version of the HADS was found to be acceptable to almost all patients (99%). Cronbach's alpha coefficient (to test reliability) has been found to be 0.78 for the HADS anxiety sub-scale and 0.86 for the HADS... more
In general the Iranian version of the HADS was found to be acceptable to almost all patients (99%). Cronbach's alpha coefficient (to test reliability) has been found to be 0.78 for the HADS anxiety sub-scale and 0.86 for the HADS depression sub-scale. Validity as performed ...
Background The Hospital Anxiety and Depression Scale (HADS) is a widely used screening tool designed as a case detector for clinically relevant anxiety and depression. Recent studies of the HADS in coronary heart disease (CHD) patients in... more
Background The Hospital Anxiety and Depression Scale (HADS) is a widely used screening tool designed as a case detector for clinically relevant anxiety and depression. Recent studies of the HADS in coronary heart disease (CHD) patients in European countries suggest it comprises three, rather than two, underlying sub-scale dimensions. The factor structure of the Chinese version of the HADS was evaluated in patients with CHD in mainland China. Methods Confirmatory factor analysis (CFA) was conducted on self-report HADS forms from 154 Chinese CHD patients. Results Little difference was observed in model fit between best performing three-factor and two-factor models. Conclusion The current observations are inconsistent with recent studies highlighting a dominant underlying tri-dimensional structure to the HADS in CHD patients. The Chinese version of the HADS may perform differently to European language versions of the instrument in patients with CHD.