Penicillamine
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Recent papers in Penicillamine
High-molecular-weight hyaluronan (HA) samples were exposed to free-radical chain-degradation reactions induced by ascorbate in the presence of Cu(II) ions - the so-called Weissberger's oxidative system. The concentrations of both... more
A urinary copper (Cu) >25 micromol/24 h following penicillamine had a reported... more
The present review provides an update of the general principles for the investigation and use of chelating agents in the treatment of intoxications by metals. The clinical use of the old chelators EDTA (ethylenediamine tetraacetate) and... more
Toxic effects of unconjugated bilirubin (BR) in neonatal hyperbilirubinemia have been related to redox and/or coordinate interactions with Cu. However, the development and mechanisms of such interactions at physiological pH have not been... more
Zinc stabilizes membranes and DNA and inhibits respiration in somatic cells. It is present in high concentrations in the male reproductive tract and may stabilize spermatozoa prior to fertilization. Herein, we evaluate... more
Young and mature Artemisia princeps var. orientalis (APO, Compositae) are used as a health food and a medicinal plant, respectively, in Korea. Here, we identified the in vitro potent peroxynitrite (ONOO−)-scavenging effect (IC50, 0.26... more
collagen can initiate platelet aggregation or whether a higher degree of polymerization is required. Purified rat skin collagen was prepared in four states. Soluble monomeric collagen, containing 2 /hM calcium chloride, was maintained at... more
Efficacy of thiol chelators viz. N-acetyl cysteine and D-penicillamine (NAC and DPA) along with nutritional supplements viz. zinc acetate, sodium selenite and magnesium sulphate (Zn, Se and Mg) in the treatment of mercury intoxication was... more
The application of(S)-N-(4-nitrophenoxycarbonyl)phenylalanine methoxyethyl ester,(S)-NIFE, as a new chiral derivatizing agent for the resolution of compounds possessing an amino group is described. Its applicability is demonstrated by the... more