ADVERSE NURSING

DRUG NAME ACTION INDICATION CONTRAINDICATION

REACTION CONSIDERATIONS
GENERIC NAME: Stimulates Management of Hypersensitivity to Local skin  Assess blood pressure
clonidine Central alpha- all grades of clonidine, sick sinus irritation, allergic and apical pulse
adrenergic hypertension. syndrome contact dermatitis, before initial dose. If
BRAND NAME: receptors to hypopigmentation systolic blood
Catapres inhibit and pressure is <90 mmhg
sympathetic hyperpigmentation or pulse is <60 bpm,
CLASSIFICATION: cardio of the skin. with hold drug and
Centrally- acting drugs accelerator and Constipation, notify physician.
vasoconstrictor depression,  Check for edema in
PREPARATION: centers. anxiety, fatigue, feet, legs daily,
Tablet nausea, anorexia,  Monitor input-output
parotid pain, sleep ratio: check for
DOSAGE: disturbances, decreasing output.
75 mcg 1 tab impotence, urinary  Note allergic
retention, itching reactions: fever, rash,
ROUTE: sensation of the pruritus, urticaria, and
Sublingual eye. ioedema.

FREQUENCY:
STAT
 ADVERSE NURSING
DRUG NAME ACTION INDICATION CONTRAINDICATION
REACTION CONSIDERATIONS
GENERIC NAME: Mefenamic acid Relief of pain Inflammatory bowel GI bleeding,  Assess patient’s
mefenamic inhibits the including disease, peptic ulcer, ulceration, pain before therapy:
enzyme muscular, neonates, coronary artery abdominal pain, location, duration,
BRAND NAME: cyclooxygenase( rheumatic, bypass(left) graft surgery, nausea with or precipitating and
Ponstan COX0-1 and traumatic, post-op severe renal impairment, without vomiting, alleviating factors.
COX-2 and and postpartum severe heart failure asthma, dyspnea,  Assess patient’s
CLASSIFICATION: reduces the pain. blurred vision who develop severe
Non-steroidal; anti formation of diarrhea and
inflammatory drug prostaglandins vomiting for
and leukotrienes. dehydration and
PREPARATION: It also acts as an electrolyte
capsule antagonist at imbalance
prostaglandin  Notify physician of
DOSAGE: receptor sites. It persistent GI
500 mg has analgesic and discomfort, sore
antipyretic throat, fever or
ROUTE: properties with malaise occur.
oral minor  Patient must be in
inflammatory full stomach to
FREQUENCY: activity. prevent gastric
Q8˚ (TID) irritation.
 ADVERSE NURSING
DRUG NAME ACTION INDICATION CONTRAINDICATION
REACTION CONSIDERATIONS
GENERIC NAME: Inhibits bacterial Skin and skin Contraindicated with allergy Skin rashes,  Assess patient’s
cefalexin cell wall structure to cephalosporins of flushing, headache previous sensitivity to
synthesis, thus infections caused penicillins. Use cautiously penicillin or other
BRAND NAME: promoting by staphylococcus with renal failure, lactation, cephalosporins.
Bioflex osmotic streptococcus. pregnancy.  Assess patient for
instability which GU infections signs and symptoms
CLASSIFICATION: eventually leads caused by E.coli of infection before
Cephalosporins (anti- to bacterial cell klebsiella. and during treatment.
infectives) death.  Assess for
anaphylaxis: rash,
PREPARATION: urticaria, pruritus,
capsule chills, fever.
 Assess renal function
DOSAGE: before and during
500mg therapy.

ROUTE:
Oral

FREQUENCY:
q6˚

C. DRUG STUDY
 ADVERSE NURSING
DRUG NAME ACTION INDICATION CONTRAINDICATION
REACTION CONSIDERATIONS
GENERIC NAME: Act directly at Active 1st stage and 2nd stage of Common: abdominal  Document indications
methylergometrine the uterine management of labor before crowning of the pain with large for therapy: onset and
maleate smooth the 3rd stage of head, primary and secondary doses, hypertension, characteristics of
muscles to labor, interior uterine inertia. headache, skin signs and symptoms.
BRAND NAME: stimulate rate, hemorrhage eruption.  Assess calcium level
Methergin tone and following before administering
amplitude or separation of the Uncommon: therapy.
CLASSIFICATION: contractions. placenta and Dizziness, nausea,  Monitor vital signs
oxytocic uterine cavity. vomiting, and note for changes
convulsions, that may indicate
PREPARATION: sweating. hemorrhage
Tablet (tachycardia,
hypotension)
DOSAGE:  Assess respiration:
0.2 mg/ml rate, rhythm and
depth.
ROUTE:  Assess for possible
Oral adverse effects.
FREQUENCY:
TID
 ADVERSE NURSING
DRUG NAME ACTION INDICATION CONTRAINDICATION
REACTION CONSIDERATIONS
GENERIC NAME: Inhibits calcium Treatment of Hypersensitivity, Dizziness,  Use caution in
nifedipine ion influx across vasospatic Cardiovascular shock flushing, severe aortic
cell membrane angina, chronic combination with headache, stenosis or severe
BRAND NAME: during cardiac stable angina, rifampicin. hypotension, hepatic impairment
Calcibloc depolarization, hypertension. peripheral edema,  Assess potential for
produces tachycardia, interaction with
CLASSIFICATION: relaxation of palpitation. other
Calcium-antagonist coronary vascular pharmacological
smooth muscle and agents or herbal
PREPARATION: peripheral vascular products patient is
tablet smooth muscle, talking that may
dilates coronary increase risk of
DOSAGE: vascular arteries, hypotension and
50mcg increase toxicity.
myocardial oxygen  Monitor BP, pulse
ROUTE: delivery on rate before therapy
Sublingual patients with  Assess therapeutic
vasospastic angina. effectiveness and
FREQUENCY: adverse reaction
STAT when starting,
adjusting done or
discontinuity.
 ADVERSE NURSING
DRUG NAME ACTION INDICATION CONTRAINDICATION
REACTION CONSIDERATIONS
GENERIC NAME: Inhibits the Treatment of Sick sinus syndrome, Palpitations,  Assess cardio
amlodipine influx of calcium hypertension second or third degree peripheral edema,
respiratory status:
ion across cell atrioventricular block, tachycardia,
BRAND NAME: membrane, to except with a functioning bradycardia, anginal pain, BP,
Norvasc produce pacemaker ventricular
pulse, respiration,
relaxation of asystoles,
CLASSIFICATION: coronary headache, fatigue, ECG.
Calcium Antagonists vascular smooth lethargy, rash,
muscle(dilatation flushing, pain or  Assess hydration and
PREPARATION: of coronary inflammation. fluid volume status:
tablet arteries),
decrease input and output
DOSAGE: peripheral ratio, presence of
5mg vascular
resistance by edema, distended
ROUTE: smooth muscle neck veins, lung
oral ( decrease blood
pressure) and crackles, adequate
FREQUENCY: increase in pulses, and skin
OD myocardial
oxygen delivery turgor.
in patients with
vasospatic
angina.

DRUG NAME ACTION INDICATION CONTRAINDICATION ADVERSE NURSING

 REACTION CONSIDERATIONS
GENERIC NAME: Competes with Treatment of Lower respiratory tract Dry mouth,  Assess for allergy
chlorpheniramine histamine for H1- allergic disorders symptoms. Herpes simplex constipation, symptoms: rhinitis,
receptor site on of allergic of the eye. Newborn or difficulty with pruritus, urticaria,
BRAND NAME: effector cells; rhinitis, premature infants. Patients micturition, watering eyes,
Antamin decreases allergic bronchial receiving monoamine blurred vision. before and
response by asthma, urticaria, oxidase inhibitors (MAOI) Delirium agitation, periodically during
CLASSIFICATION: blocking vasomotor (non therapy. Hyperthyroidism, insomnia. treatment
Anti-histamine histamine. allergic) rhinitis, hypertension, coronary Jaundice, postural  Assess respiratory
contact disease. hypotension. status and increase
PREPARATION: dermatoses, food Cardiac in bronchial
Ampoule and drug allergy arrhythmias secretions, wheezing
and insect bites. including atrial or chest tightness
DOSAGE: arrhythmia.  Monitor I & O: be
1 amp alert for urinary
retention, frequency,
ROUTE: dysuria, esp. elderly;
IV drug should be
discontinued if these
FREQUENCY: occur.
STAT
 ADVERSE NURSING
DRUG NAME ACTION INDICATION CONTRAINDICATION
REACTION CONSIDERATIONS
GENERIC NAME: Provides/Replac Prevention and Hypersensitivity to any GI irritation,  Instruct patient not to
ferrous sulfate es elemental treatment of ingredient, hemosiderosis, anorexia, nausea, substitute one iron salt
ion, an essential iron-deficiency hemolytic anemia, vomiting, diarrhea, for another because
BRAND NAME: component in anemia. constipation, dark they have different
Ferrous sulfate formation of stool. Teeth elemental iron
hemoglobin in staining with content.
CLASSIFICATION: red blood cell liquid formulation.
Iron supplement development.  Swallow the whole
Ferrous tablet, do not chew or
PREPARATION: fumarate crush.
Tablet contains 33%
elemental iron,
DOSAGE: ferrous  Do not double the
325 mg gluconate- 12%, dose if missed, but
ferrous sulfate- take it as soon as
ROUTE: 20% ferrous remembered and
Oral sulfate avoid taking drug
dessicated- 30% with certain foods that
FREQUENCY: may impair oral iron
OD absorption like
yogurt, cheese, eggs,
milk cereals tea and
coffee.
 ADVERSE NURSING
DRUG NAME ACTION INDICATION CONTRAINDICATION
REACTION CONSIDERATION

GENERIC NAME: Blocks response to Treatment of 2nd or 3rd degree heart block, Postural,  Obtain history of
Atenolol beta stimulation hypertension. severe bradycardia, shock, hypotension, patient underlying
and depresses uncontrolled heart failure, Dizziness, condition
BRAND NAME: Headache, (hypertension,
rennin secretion asthma, history of chronic
Therabloc GI upset angina)
obstructive airways disease,
 Monitor the blood
CLASSIFICATION: hepatic impairement. pressure frequently,
Antihypertensive Drug BP must be <
Beta-blocker 100/60.
 Always check for
PREPARATION: apical pulse of the
Tablet
patient before giving
DOSAGE: this drug; if slower
50mg than 60 beats
/minute, hold the
ROUTE: drug and call the
oral doctor.

FREQUENCY:
OD