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    Janice Malafu De Guia
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    Boric acid can exist as transparent scales, six-sided crystals, or a white powder. It is soluble in water, alcohol, glycerin, and boiling water/alcohol. Boric acid content is determined through acid-base titration with NaOH in the presence of glycerol, forming glyceryl boric acid which acts as a strong acid. It has synonyms including Sal Sedativum Hombergi. Boric acid is prepared in dosage forms such as dusting powders, solutions, suppositories, ointments, and eyewash. It is used as an antiseptic, antifungal, and emollient for skin diseases and burns.

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    Boric acid can exist as transparent scales, six-sided crystals, or a white powder. It is soluble in water, alcohol, glycerin, and boiling water/alcohol. Boric acid content is determined through acid-base titration with NaOH in the presence of glycerol, forming glyceryl boric acid which acts as a strong acid. It has synonyms including Sal Sedativum Hombergi. Boric acid is prepared in dosage forms such as dusting powders, solutions, suppositories, ointments, and eyewash. It is used as an antiseptic, antifungal, and emollient for skin diseases and burns.

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    833 views1 page

    Inorgmedlab Exp7

    Uploaded by

    Janice Malafu De Guia
    Boric acid can exist as transparent scales, six-sided crystals, or a white powder. It is soluble in water, alcohol, glycerin, and boiling water/alcohol. Boric acid content is determined through acid-base titration with NaOH in the presence of glycerol, forming glyceryl boric acid which acts as a strong acid. It has synonyms including Sal Sedativum Hombergi. Boric acid is prepared in dosage forms such as dusting powders, solutions, suppositories, ointments, and eyewash. It is used as an antiseptic, antifungal, and emollient for skin diseases and burns.

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    of 1

    QUESTIONS FOR RESEARCH:

    1. What are the 3 physical occurrence of boric acid in the market?


    transparent, colorless, odorless, pearly scales having a smooth feel
    six-sided triclinic crystals
    white, odorless, bulky powder which is unctuous to touch

    2. Using the different descriptive terms to describe solubility (refer to USP) of


    substance, express the solubility of boric acid.
    - Boric acid is soluble in
    1gram-18ml of water (soluble)
    1gram-18ml of alcohol (soluble)
    1gram-4ml glycerin(freely soluble)
    1gram-4ml boiling water (freely soluble)
    1gram-6ml boiling alcohol (freely soluble)

    3. How is the boric acid assayed? What is the rationale for such procedure?
    - Purpose: To determine the percentage of purity in a given amount of the
    boric acid
    - Procedure: It is determined by the acid-base titration, i.e. direct titration
    method with 1N NaOH method.
    - Rationale:
    Boric acid is a weak acid and hence it cannot be determined quantitatively
    in an aqueous solution with standard NaOH solution using visual indicator.
    However, it can be determined by titrating with standard NaOH solution in
    the presence of polyhydric alcohols, such as glycerol or mannitol because
    glyceryl boric acid which is formed on treatment of boric acid with glycerol.
    This glyceryl boric acid acts as a strong acid and can be titrated against a
    standard NaOH solution using a visual indicator, phenolphthalein.

    4. List Synonyms of boric acid.


    Sal Sedativum Hombergi
    orthoboric acid
    boracic acid
    acidum boricum
    borofax

    5. In what dosage forms is boric acid prepared?


    Dusting powders
    Solution
    Suppository
    Ointment
    Eyewash

    6. State and define the medicinal uses of boric acid.


    -Antiseptic (cleanse cuts and wounds)
    -Antifungal (kills bacterias and fungi)
    -Emollient Indicated for skin diseases (eczema, impetigo, erysipelas) and burns

    REFERENCES:
    http://www.citycollegiate.com/boric_acid.htm
    http://www.sigmaaldrich.com/content/dam/sigma-
    aldrich/docs/Sigma/Product_Information_Sheet/b7901pis.pdf

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