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    Drug Study

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    Clozapine (Clozaril) is an antipsychotic medication used to treat schizophrenia in patients who have not responded adequately to other treatments or who cannot tolerate standard antipsychotics. It works by binding to dopamine receptors in the central nervous system and also has anticholinergic and alpha-adrenergic blocking activity. Common adverse reactions include CNS effects like seizures, dizziness, and sedation as well as gastrointestinal issues and hematological abnormalities. Nurses must monitor patients closely for signs of neuroleptic malignant syndrome and seizures when starting or adjusting clozapine treatment.

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    Drug Study

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    108 views2 pages
    Clozapine (Clozaril) is an antipsychotic medication used to treat schizophrenia in patients who have not responded adequately to other treatments or who cannot tolerate standard antipsychotics. It works by binding to dopamine receptors in the central nervous system and also has anticholinergic and alpha-adrenergic blocking activity. Common adverse reactions include CNS effects like seizures, dizziness, and sedation as well as gastrointestinal issues and hematological abnormalities. Nurses must monitor patients closely for signs of neuroleptic malignant syndrome and seizures when starting or adjusting clozapine treatment.

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    Clozapine

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    Clozapine (Clozaril) is an antipsychotic medication used to treat schizophrenia in patients who have not responded adequately to other treatments or who cannot tolerate standard antipsychotics. It works by binding to dopamine receptors in the central nervous system and also has anticholinergic and alpha-adrenergic blocking activity. Common adverse reactions include CNS effects like seizures, dizziness, and sedation as well as gastrointestinal issues and hematological abnormalities. Nurses must monitor patients closely for signs of neuroleptic malignant syndrome and seizures when starting or adjusting clozapine treatment.

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    108 views2 pages

    Drug Study

    Uploaded by

    unkown user
    Clozapine (Clozaril) is an antipsychotic medication used to treat schizophrenia in patients who have not responded adequately to other treatments or who cannot tolerate standard antipsychotics. It works by binding to dopamine receptors in the central nervous system and also has anticholinergic and alpha-adrenergic blocking activity. Common adverse reactions include CNS effects like seizures, dizziness, and sedation as well as gastrointestinal issues and hematological abnormalities. Nurses must monitor patients closely for signs of neuroleptic malignant syndrome and seizures when starting or adjusting clozapine treatment.

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    DRUG STUDY

    Date Generic Brand Classificat Indication


    Mechanism Dosage & Time Adverse Nursing
    Name Name ion of Action Frequency Given Reaction Consideration
    03-24- Clozapine Clozaril Therapeut Schizophr Binds to 12.5 mg CNS: · Watch for
    21 ic: enia dopamine orally NEUROLE and report signs
    antipsych unrespon receptors twice a PTIC of neuroleptic
    otics sive to or in the CNS. day MALIGNAN malignant
    intolerant Also has T syndrome,
    Pharmaco of anticholiner SYNDROM including
    logic: standard gic and E, hyperthermia,
    tricyclic therapy alpha- SEIZURES diaphoresis,
    dibenzodi with other adrenergic , dizziness, generalized
    azepines antipsych blocking sedation. muscle rigidity,
    otics activity. EENT: altered mental
    (treatment Produces visual status,
    refractory) fewer disturbance tachycardia,
    . To extrapyram s. CV: changes in
    reduce idal MYOCARD blood pressure
    recurrent reactions ITIS, (BP), and
    suicidal and less hypotensio incontinence.
    behavior tardive n, Symptoms
    in dyskinesia tachycardia typically occur
    schizophr than , ECG within 4–14
    enic standard changes, days after
    patients. antipsychot hypertensio initiation of
    ics but n. GI: drug therapy,
    carries high constipatio but can occur at
    risk of n, any time during
    hematologi abdominal drug use.
    c discomfort,
    abnormaliti dry mouth, · Be alert for
    es. ↑ salivation, new seizures or
    Therapeuti nausea, increased
    c Effects: vomiting, seizure activity,
    Diminished weight especially at
    schizophre gain. the onset of
    nic Derm: drug treatment.
    behavior. rash, Document the
    Diminished sweating. number,
    suicidal Endo: duration, and
    behavior. hyperglyce severity of
    mia. seizures, and
    Hemat: report these
    AGRANUL findings
    OCYTOSIS immediately to

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