Aclan Özder
Bezmialem Vakif University, Family Medicine, Faculty Member
- I am an Associate Professor of Family Medicine working at Bezmialem Vakif University, Istanbul, Turkey.edit
Research Interests: Occupational Health, Family Medicine, Quality of life, Turkey, Medicine, and 15 moreHumans, Female, Male, Physicians, Sleep, Clinical Sciences, Prevalence, Adult, Occupational Exposure, Public health systems and services research, Task Performance and Analysis, Sleep-Wake Disorders, Surveys and Questionnaires, Epworth sleepiness scale, and Excessive Daytime Sleepiness
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Research Interests: Endocrinology, Primary Health Care, Turkey, Medicine, Humans, and 15 moreInternal Medicine, Blood Glucose, Diabetes mellitus, Female, Male, Triglycerides, LDL-cholesterol, Middle Aged, Fatty Liver, Adult, Dyslipidemia, Lipid Profile, Cross Sectional Studies, Blood Lipids, and Medical biochemistry and metabolomics
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Research Interests: Surgery, Medicine, Constipation, Impaction, Perforation, and 3 moreColostomy, Abdominal Pain, and defecation
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Objective: Gassal is the name of the profession which mainly involves bathing and dressing of dead bodies in gassalhome. It is a profession defined in Islamic culture and has similarities with mortician. In this study; it was aimed to... more
Objective: Gassal is the name of the profession which mainly involves bathing and dressing of dead bodies in gassalhome. It is a profession defined in Islamic culture and has similarities with mortician. In this study; it was aimed to determine burnout levels of gassals and to compare them with those of other workers in cemetery. Material and Method: Fifty-seven gassals, 51 grave diggers and 45 administrative staff were included into the study. All participants were asked to answer a form for demographical variables, Maslach Burnout Inventory (MBI), StateTrait Anxiety Inventory (STAI-S and STAI-T) and Beck Depression Inventory (BDI). Results: Emotional exhaustion, depersonalization, personal accomplishment scores were insignificant within groups although there was a trend to be higher in administrative staff in depersonalization (p:0.092). There were no significances within groups among STAI-S (p:0.229) and STAI-T (p:0.233). The Beck depression score was significantly higher in mort...
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Objective: To evaluate the inflammatory cells in the complete blood count test and their relationship with the glycaemic control in type 2 diabetes patients. ---Continue
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Research Interests: Primary Care and Medicine
Aims: This study evaluated the prevalence of, and the risk factors for, obstructive sleep apnoea syndrome (OSAS) and excessive day time sleepiness (EDS) as well as its relation to road traffic accidents (RTA) among Turkish public... more
Aims: This study evaluated the prevalence of, and the risk factors for, obstructive sleep apnoea syndrome (OSAS) and excessive day time sleepiness (EDS) as well as its relation to road traffic accidents (RTA) among Turkish public transportation drivers. Materials and methods: Male public transportation drivers (618) from the largest public transportation corporation (IETT) in Turkey were analysed after responding to questionnaires about their demographics, traffic accident histories, sleep habits, excessive daytime sleepiness (Epworth), and the likelihood of having apnoea (STOP-BANG). We also measured anthropometric data for all of the drivers. Frequency, mean, Chi-square, student T-test and regression analyses were used in statistical analyses. Results: Six hundred and eighteen male public transportation bus drivers with mean age (years) of 43.08 ± 5.41 and with mean BMI (kg/m2) 29.01 ± 3.92 were recruited. There was a positive and significant relation between age and BMI with obst...
Özet Yazışma Adresi/Corresponding to: Hasan Hüseyin Eker, Namık Kemal Mah Tunç Sok No: 13/8 Ümraniye İstanbul/Türkiye Tel: 0 505 715 42 40 e-mail: hheker@yahoo.com Objective: In this study, evaluation of hygiene applications and... more
Özet Yazışma Adresi/Corresponding to: Hasan Hüseyin Eker, Namık Kemal Mah Tunç Sok No: 13/8 Ümraniye İstanbul/Türkiye Tel: 0 505 715 42 40 e-mail: hheker@yahoo.com Objective: In this study, evaluation of hygiene applications and protective equipment usage and hygiene applications of attendants working in İstanbul Education and Research Hospital has been the primary objective. Materials and Method: This definitive type investigation has been conducted by applying a face to face survey form consisting of 29 questions directed to 332 attendants working in İstanbul Education and Research Hospital and who have accepted to participate in the study. Findings: 78.6% of participants have stated that they were wearing gloves; 31% that they were using bonnet-headdress-hats; 47.3% that they were using masks; 71.1% have said that they were washing their hands after toilet and 62.7% were washing up before lunch. 41% of attendants have stated they have been educated before working and 84.2% after ...
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Background: In our role as a preventive physician, there is a need for cheap and accessible biochemical markers that will allow the determination of the risk of coronary artery disease. We aimed to research the value of glycosylated... more
Background: In our role as a preventive physician, there is a need for cheap and accessible biochemical markers that will allow the determination of the risk of coronary artery disease. We aimed to research the value of glycosylated haemoglobin (HbA1c) in the prediction of coronary artery disease. Methods: Patients aged between thirty and ninety years who were admitted to outpatient clinic of Cardiology department in a university hospital between January 2016 and June 2018 for angiography for various reasons were retrospectively screened. Patients with known diabetes or patients with HbA1c of 6.5 or above were excluded from the study. Comparative HbA1c data were obtained according to the stenosis groups and statistical significance was sought. Logistic regression analysis was used to investigate the risk factors affecting stenosis positivity. Results: A total of 247 patients were identified, 120 patients without any stenosis in any coronary artery, 56 patients with> 50% stenosis ...
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Research Interests: Surgery, Medicine, Constipation, Impaction, Perforation, and 3 moreColostomy, Abdominal Pain, and defecation
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The aim of this study was to assess the quality of life and degree of satisfaction with the treatment of patients with type 2 diabetes mellitus (T2DM) in primary health care in Turkey. A total of 180 adults with type 2 diabetes mellitus... more
The aim of this study was to assess the quality of life and degree of satisfaction with the treatment of patients with type 2 diabetes mellitus (T2DM) in primary health care in Turkey. A total of 180 adults with type 2 diabetes mellitus from the Family Medicine outpatient clinic were included in the study. Participants were asked to fill out a self-report survey to collect data via two well validated scales, including the Turkish version of the Audit of Diabetes Dependent Quality of Life (ADDQoL) instrument and the Diabetes Treatment Satisfaction Questionnaire (DTSQ). Overall average weighted impact score for the study group was-2.73 ± 2.56. Diabetes mellitus has the largest impact on enjoyment of food (mean ± SD impact rating:-1.63 ± 1.50). The mean score of the DTSQ was 21.02 ± 8.07 (range from better to worse: 36 to 0) for the entire group. Presence of diabetes-related complication was significantly related with lower treatment satisfaction scores (mean ± SD = 23.08 ± 7.32 withou...
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The aim of this study was to compare mean platelet volume (MPV) in patients with type 2 diabetes mel-litus (T2DM), in subjects with impaired fasting glucose (IFG), and in non-diabetic controls. A total of 201 adults with T2DM and 201... more
The aim of this study was to compare mean platelet volume (MPV) in patients with type 2 diabetes mel-litus (T2DM), in subjects with impaired fasting glucose (IFG), and in non-diabetic controls. A total of 201 adults with T2DM and 201 subjects with IFG from the Family Medicine outpatient clinic as well as 201 healthy controls were included in the study. We measured blood fasting glucose, complete blood count and LDL-cholesterol and compared the results between the groups enrolled. In the patients with diabetes and subjects with IFG, MPV was significantly higher (10.66 ± 0.94 fL and 10.49 ± 0.96 fL, respectively) as compared to the non-diabetic group (10.04 ± 1.01 fL) (p = 0.000). Among the diabetic subjects, a positive statistical Pearson correlation was seen between MPV and HbA1c levels (r = 0.357; p = 0.000) and fasting blood glucose (FBG) levels (r = 0.306; p = 0.000). The mean MPV in patients having HbA1C < 7.5% was 10.17 ± 0.83 fL and significantly lower than that of patients...
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Summary Objectives. This study aims to examine the frequency of exposure of health care providers to aggres - sion and violence at work, and the effective factors thereon, as well as the effects of violence on health care providers.... more
Summary Objectives. This study aims to examine the frequency of exposure of health care providers to aggres - sion and violence at work, and the effective factors thereon, as well as the effects of violence on health care providers. Materials and Methods. This cross-sectional type study has been conducted in Istanbul Training and research Hospital (IEAH) (219) and bayrampasa State Hospital (bDH) (64) in April 2010. The question - naire prepared by researchers has been filled in through face-to-face meetings with a total of 283 health care providers, who accepted to take part in the study. The resulting data have been assessed and eval- uated through SPSS 11.5 package program. Results. 66.8% of the respondents reported that they had been exposed to violence and aggression dur - ing the recent one year, the most frequent type thereof being verbal violence (86.8%). 90.2% of the health care providers exposed to violence at work stated that the applicable current laws do not protect the ...
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Amac: Ulkemizde hemsireler yuksek saatlerde ve fazla is yuku ile calistiklari gozlenmistir. Bu durumun onlarin yasam kalitelerini etkileyebilecegi dusunulmustur. Bu arastirma hemsirelerde gunduz uykululuk duzeyleri, gece uyku duzenleri ve... more
Amac: Ulkemizde hemsireler yuksek saatlerde ve fazla is yuku ile calistiklari gozlenmistir. Bu durumun onlarin yasam kalitelerini etkileyebilecegi dusunulmustur. Bu arastirma hemsirelerde gunduz uykululuk duzeyleri, gece uyku duzenleri ve buna etki eden faktorleri arastirmak amaciyla yapilmistir. Gerec ve yontem : Kesitsel olarak yapilan bu arastirma 2014 yili Haziran-Temmuz aylarinda Bezmialem Vakif Universitesi Tip Fakultesi Hastanesinde calisan hemsirelerle yapilmistir. Veri toplama araci olarak, sosyodemografik sorular, Epworth uykululuk olcegi ve EuroQol-5 (EQ-5D) yasam kalitesi olcegi kullanmistir. Olusturulan anket formu elektronik ortamda mail yolu ile tum hemsirelere gonderilmistir. Arastirmaya katilan hemsirelere ait verilerin degerlendirilmesinde, SPSS for Windows 16.0 istatistik programi kullanilmistir. Istatistiksel analizlerde siklik, aritmatik ortalama, chi kare ve sutudent t tesleri kullanilistir. Istatiksel olarak p<0,05 anlamli olarak kabul edilmistir. Bulgula...
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This study aimed to estimate the prevalence of dysmenorrhea among Turkish university students studying in the field of health sciences and to evaluate the effects of the students’ socio-demographic characteristics on the condition. A... more
This study aimed to estimate the prevalence of dysmenorrhea among Turkish university students studying in the field of health sciences and to evaluate the effects of the students’ socio-demographic characteristics on the condition. A cross-sectional survey of 658 students was conducted by questionnaire at a health sciences university in Turkey. A structured questionnaire was used to collect data on dysmenorrhea. Health related quality of life (HRQoL) was assessed using the generic 36-Item Short Form Health Survey (SF-36), and depressive symptoms were assessed with the BDI included in the survey. A visual analogue scale was used to assess the severity of dysmenorrhea. Data were analyzed using chi-square tests and logistic regression analysis. The prevalence of dysmenorrhea was 79.7% (524 out of 658 students). Age of menarche (P = 0.001), menstrual flow (P = 0.000), drinking coffee (P = 0.001) and having a family history of dysmenorrhea were significantly associated with dysmenorrhea ...
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BACKGROUND The nuclear receptors Rev-erb alpha and Rev-erb beta are transcription factors that regulate the function of genes in glucose and lipid metabolism, and they also form a link between circadian rhythm and metabolism. We evaluated... more
BACKGROUND The nuclear receptors Rev-erb alpha and Rev-erb beta are transcription factors that regulate the function of genes in glucose and lipid metabolism, and they also form a link between circadian rhythm and metabolism. We evaluated the variations in Rev-erb alpha and Rev-erb beta genes together with biochemical parameters as risk factors in type 2 diabetic (T2DM) patients. METHODS Molecular analyses of Rev-erb alpha and Rev-erb beta genes were performed on genomic DNA by using next-generation sequencing in 42 T2DM patients (21 obese and 21 non-obese) and 66 healthy controls. RESULTS We found 26 rare mutations in the study groups, including 13 missense mutations, 9 silent mutations, 3 5'UTR variations, and a 3'UTR variation, of which 9 were novel variations (5 missense and 3 silent and 1 5'UTR). Six common variations were also found in the Rev-erb genes; Rev-erb beta Chr3:24003765 A>G, Rev-erb beta rs924403442 (Chr3:24006717) G>T, Rev-erb alpha Chr17:38253751 T>C, Rev-erb alpha rs72836608 C>A, Rev-erb alpha rs2314339 C>T and Rev-erb alpha rs2102928 C>T. Of these, Rev-erb beta Chr3:24003765 A>G was a novel missense mutation (p.Q197R), while others were identified as intronic variants. T2DM patients with Rev-erb beta rs924403442 T allele had lower body surface area (BSA) than noncarriers (GG genotype) (p=0.039). Rev-erb alpha rs72836608 A allele and Rev-erb alpha rs2314339 CC genotype were associated with decreased serum HDL-cholesterol levels in T2DM patients (p=0.025 and p=0.027, respectively). In our study, different effects of Rev-erbs polymorphisms were found according to gender and presence of obesity. Rev-erb alpha rs72836608 (C>A) and rs2314339 (C>T) and Rev-erb alpha rs2102928 (C>T) were associated with low HDL-C levels in male T2DM patients. In female patients, Rev-erb alpha rs2102928 (C>T) was associated with high microalbuminuria and Rev-erb beta rs9244403442 G>T was associated with low HDL and high BSA values. In addition, Rev-erb alpha Chr17: 38253751 (T>C), rs72836608 (C>A), and rs2314339 (C>T) and Rev-erb beta Chr3:24003765 (A>G) were associated with increased serum GGT levels in obese T2DM patients. In non-obese patients, Rev-erbs SNPs had no effect on serum GGT levels. CONCLUSION Our findings indicate that variations in the Rev-erb alpha and Rev-erb beta genes can affect metabolic changes in T2DM and these effects may vary depending on gender and obesity.
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The aim of this study was to assess the quality of life and degree of satisfaction with the treatment of patients with type 2 diabetes mellitus (T2DM) in primary health care in Turkey. A total of 180 adults with type 2 diabetes mellitus... more
The aim of this study was to assess the quality of life and degree of satisfaction with the treatment of patients with type 2 diabetes mellitus (T2DM) in primary health care in Turkey. A total of 180 adults with type 2 diabetes mellitus from the Family Medicine out-patient clinic were included in the study. Participants were asked to fill out a self-report survey to collect data via two well validated scales, including the Turkish version of the Audit of Diabetes Dependent Quality of Life (ADDQoL) instrument and the Diabetes Treatment Satisfaction Questionnaire (DTSQ). Overall average weighted impact score for the study group was -2.73 ± 2.56. Diabetes mellitus has the largest impact on enjoyment of food (mean ± SD impact rating: -1.63 ± 1.50). The mean score of the DTSQ was 21.02 ± 8.07 (range from better to worse: 36 to 0) for the entire group. Presence of diabetes-related complication was significantly related with lower treatment satisfaction scores (mean ± SD = 23.08 ± 7.32 wit...
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The aim of this study was to estimate the prevalence of individuals who are at high risk for state and trait anxiety as well as to investigate the relationship of anxiety levels of urban transportation drivers from Istanbul, Turkey with... more
The aim of this study was to estimate the prevalence of individuals who are at high risk for state and trait anxiety as well as to investigate the relationship of anxiety levels of urban transportation drivers from Istanbul, Turkey with restless legs syndrome (RLS). The data was gathered between April 2013 and June 2013 by the use of a questionnaire prepared for the purpose of this study, completed anonymously. Restless leg syndrome and anxiety level were evaluated in the group; data obtained was analyzed using the SPSS version 16. Chi-square, correlation and student-t tests were used. Restless leg syndrome symptoms were determined by a self-assessment questionnaire, including the International Restless Legs Syndrome Study Group (IRLSSG) diagnostic criteria, to determine RLS symptoms and Spielberger State-Trait Anxiety Inventory (STAI) to determine anxiety levels of the participants. In the present study, the four RLS criteria were reported in 31.2%. STAI-state and STAI-trait scores...
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The aim of this study was to compare mean platelet volume (MPV) in patients with type 2 diabetes mellitus (T2DM), in subjects with impaired fasting glucose (IFG), and in non-diabetic controls. A total of 201 adults with T2DM and 201... more
The aim of this study was to compare mean platelet volume (MPV) in patients with type 2 diabetes mellitus (T2DM), in subjects with impaired fasting glucose (IFG), and in non-diabetic controls. A total of 201 adults with T2DM and 201 subjects with IFG from the Family Medicine out-patient clinic as well as 201 healthy controls were included in the study. We measured blood fasting glucose, complete blood count and LDL-cholesterol and compared the results between the groups enrolled. In the patients with diabetes and subjects with IFG, MPV was significantly higher (10.66 ± 0.94 fL and 10.49 ± 0.96 fL, respectively ) as compared to the non-diabetic group (10.04 ± 1.01 fL) (p = 0.000). Among the diabetic subjects, a positive statistical Pearson correlation was seen between MPV and HbA1c levels (r = 0.357; p = 0.000) and fasting blood glucose (FBG) levels (r = 0.306; p = 0.000). The mean MPV in patients having HbA1C < 7.5% was 10.17 ± 0.83 fL and significantly lower than that of patient...
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Research Interests: Immunology and Medicine
Objectives. This study aims to examine the frequency of exposure of health care providers to aggression and violence at work, and the effective factors thereon, as well as the effects of violence on health care providers. Materials and... more
Objectives. This study aims to examine the frequency of exposure of health care providers to aggression and violence at work, and the effective factors thereon, as well as the effects of violence on health care providers. Materials and Methods. This cross-sectional type study has been conducted in Istanbul Training and research Hospital (IEAH) (219) and bayrampasa State Hospital (bDH) (64) in April 2010. The questionnaire prepared by researchers has been filled in through face-to-face meetings with a total of 283 health care providers, who accepted to take part in the study. The resulting data have been assessed and evaluated through SPSS 11.5 package program. Results. 66.8% of the respondents reported that they had been exposed to violence and aggression during the recent one year, the most frequent type thereof being verbal violence (86.8%). 90.2% of the health care providers exposed to violence at work stated that the applicable current laws do not protect the staff against violence, and 88.3% thereof stated that their institution have not supported them upon an act of violence. A statistically significant difference in the frequency of exposure to violence has been detected between age, seniority at work, place of exposure to violence, and profession of the health care staff (p<0.05). Approximately half of the health care providers opine that their behavior towards patients has been negatively affected from violence. It is noted that such negative behavior change is even higher in females, staff with a frequency of violence > 5, assistants, and staff who believe that security at work is at risk in their institution (p<0.05). Conclusions. Around 1/3 rd of the health care providers have reported that they have been exposed to violence at least once during the recent one year, and half of those exposed to violence have stated that their behavior towards patients has been negatively affected therefrom. violence / health care providers / psychiatry
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Objectives. This study aims to examine the frequency of exposure of health care providers to aggression and violence at work, and the effective factors thereon, as well as the effects of violence on health care providers. Materials and... more
Objectives. This study aims to examine the frequency of exposure of health care providers to aggression and violence at work, and the effective factors thereon, as well as the effects of violence on health care providers. Materials and Methods. This cross-sectional type study has been conducted in Istanbul Training and research Hospital (IEAH) (219) and bayrampasa State Hospital (bDH) (64) in April 2010. The questionnaire prepared by researchers has been filled in through face-to-face meetings with a total of 283 health care providers, who accepted to take part in the study. The resulting data have been assessed and evaluated through SPSS 11.5 package program. Results. 66.8% of the respondents reported that they had been exposed to violence and aggression during the recent one year, the most frequent type thereof being verbal violence (86.8%). 90.2% of the health care providers exposed to violence at work stated that the applicable current laws do not protect the staff against violence, and 88.3% thereof stated that their institution have not supported them upon an act of violence. A statistically significant difference in the frequency of exposure to violence has been detected between age, seniority at work, place of exposure to violence, and profession of the health care staff (p<0.05). Approximately half of the health care providers opine that their behavior towards patients has been negatively affected from violence. It is noted that such negative behavior change is even higher in females, staff with a frequency of violence > 5, assistants, and staff who believe that security at work is at risk in their institution (p<0.05). Conclusions. Around 1/3 rd of the health care providers have reported that they have been exposed to violence at least once during the recent one year, and half of those exposed to violence have stated that their behavior towards patients has been negatively affected therefrom. violence / health care providers / psychiatry