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David Hall
  • 8, Homeground, Buckingham, England, UK
  • 01280 814684

David Hall

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ABSTRACT
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CloudyIT is a trusted name in the market providing you premium quality IT support and solutions to precious clients in UK.
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Diaphorina citri Kuwayama is the primary vector of Huanglongbing, the most devastating disease of citrus. D. citri populations in Puerto Rico were monitored with yellow sticky traps on citrus trees or other psyllid host plants at... more
Diaphorina citri Kuwayama is the primary vector of Huanglongbing, the most devastating disease of citrus. D. citri populations in Puerto Rico were monitored with yellow sticky traps on citrus trees or other psyllid host plants at different elevations, ranging from 10 to 880 m above sea level. Trapping was conducted in March through May of 2013 and 2014 when psyllid populations usually are highest. Population levels of D. citri, based on the trapping data, varied among the sites, and there was a strong trend in both years for decreasing psyllid abundance with increased elevation based on the number of psyllids captured on traps and the proportion of trees shown to be infested. No psyllids were collected at an elevation of >600 m. Reduced populations at higher elevations could be a consequence of differences in temperature, air pressure, oxygen levels, ultraviolet light, or other factors alone or in combination. We discuss our results as they pertain to management of D. citri and H...
The asian citrus psyllid Diaphorina citri Kuwayama, is an important pest of citrus because it transmits phloem- limited bacteria (Candidatus Liberibacter spp.) responsible for citrus greening disease (huanglongbing), considered by some to... more
The asian citrus psyllid Diaphorina citri Kuwayama, is an important pest of citrus because it transmits phloem- limited bacteria (Candidatus Liberibacter spp.) responsible for citrus greening disease (huanglongbing), considered by some to be the world's most serious disease of citrus. The psyllid has slowly spread throughout southern Asia, the Saudi Arabian Peninsula, to some islands in the Indian Ocean, and to Reunion and Mauritius to the east of southern Africa. Huanglongbing has also spread throughout most of these regions. D. citri was first reported in the Americas in Brazil during the 1940s, but huanglongbing was not observed in Brazil until 2004. Since the 1990s, the psyllid has invaded a number of New World countries in the Caribbean, West Indies, and North and Central America including the United States (Florida and Texas) and Mexico. So far in these newly-invaded New World countries, huanglongbing has only been detected in the United States (Florida), where it was fir...
Creating new molecules that simultaneously enhance tumor cell killing and permit diagnostic tracking is vital to overcoming the limitations rendering current therapeutic regimens for terminal cancers ineffective. Accordingly, we... more
Creating new molecules that simultaneously enhance tumor cell killing and permit diagnostic tracking is vital to overcoming the limitations rendering current therapeutic regimens for terminal cancers ineffective. Accordingly, we investigated the efficacy of an innovative new multi-functional targeted anti-cancer molecule, SM7L, using models of the lethal brain tumor Glioblastoma multiforme (GBM). Designed using predictive computer modeling, SM7L incorporates the therapeutic activity of the promising anti-tumor cytokine MDA-7/IL-24, an enhanced secretory domain, and diagnostic domain for non-invasive tracking. In vitro assays revealed the diagnostic domain of SM7L produced robust photon emission, while the therapeutic domain showed marked anti-tumor efficacy and significant modulation of p38MAPK and ERK pathways. In vivo, the unique multi-functional nature of SM7L allowed simultaneous real-time monitoring of both SM7L delivery and anti-tumor efficacy. Utilizing engineered stem cells as novel delivery vehicles for SM7L therapy (SC-SM7L), we demonstrate that SC-SM7L significantly improved pharmacokinetics and attenuated progression of established peripheral and intracranial human GBM xenografts. Furthermore, SC-SM7L anti-tumor efficacy was augmented in vitro and in vivo by concurrent activation of caspase-mediated apoptosis induced by adjuvant SC-mediated S-TRAIL delivery. Collectively, these studies define a promising new approach to treating highly aggressive cancers, including GBM, using the optimized therapeutic molecule SM7L.
During July 16-23, 2001, Belize was explored for parasitoids attacking eggs of citrus weevils. The trip, organized by coauthors Peña and Hall and funded by a grant from the Florida Citrus Production Research Advisory Council (981-42E),... more
During July 16-23, 2001, Belize was explored for parasitoids attacking eggs of citrus weevils. The trip, organized by coauthors Peña and Hall and funded by a grant from the Florida Citrus Production Research Advisory Council (981-42E), was made in hopes of ...
Fall armyworm is a signiÞcant agricultural pest in the United States, affecting most notably sweet corn and turfgrass. Two morphologically identical strains, rice strain (R-strain) and corn strain (C-strain), exist that differ... more
Fall armyworm is a signiÞcant agricultural pest in the United States, affecting most notably sweet corn and turfgrass. Two morphologically identical strains, rice strain (R-strain) and corn strain (C-strain), exist that differ physiologically and behaviorally and can be identiÞed by mito- chondrial haplotyping. Recent studies of overwintering populations in Florida indicate that the mitochondrial lineage associated with the R-strain itself
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