- Forensic Genetics, Forensic Science, Reliability of forensic science evidence, Facial Image Comparison, Facial Comparison, Facial Comparison Evidence, and 20 moreComputer Facial Animation, Prehistoric Archaeology, Criminal Justice, Facial Reconstruction, Forensic Facial Reconstruction, Facial Approximation, Forensic Anthropology, Ancient Greek History, Forensic Archaeology, Criminal Justice History, Rape and Sexual Assault Law, Ancient DNA (Archaeology), Ancient DNA Research, Forensic Pathology, Disaster Victim Identification, Transitional Justice, British Prehistory (Archaeology), Human Identification (Forensic Anthropology), Forensic Facial Identification, and Forensic Medicineedit
- Martin Evison graduated in genetics from the University of Newcastle Upon Tyne in 1982. After a period of graduate st... moreMartin Evison graduated in genetics from the University of Newcastle Upon Tyne in 1982. After a period of graduate study, work and travel in New Zealand and Australia, he pursued a six-year professional career in computing. He returned to academia in 1992 completing the MSc in Environmental Archaeology at Sheffield University. Martin’s academic background in genetics and archaeology allowed him to continue to doctoral research in low-template DNA analysis in a project co-supervised with Trent Centre, National Blood Service. His work included a comprehensive statistical study of the patterns of intrusive contamination of DNA encountered when using extended-cycle PCR. Martin’s knowledge of computer systems led him to join a research project in computerised forensic facial reconstruction with the Department of Forensic Pathology at Sheffield Medico-Legal Centre, where he developed early Internet-based visualisation models. Analysis of skeletal material reported to the Centre led him to develop a practice in that area and, with the kind support of colleagues in the Department he was able to establish a research group in human identification, which undertook a range of scientific projects and consultancy work.
In 2005, Martin joined the University of Toronto as Director of the Forensic Science Program—the longest standing forensic science degree programme in Canada. In 2010, he returned to the UK to direct Northumbria University Centre for Forensic Science—a highly-interdisciplinary research group successfully returned to the UK Research Excellence Framework in 2014. Martin has undertaken case work in forensic facial comparison, forensic archaeology and anthropology, and where innocent transfer or contamination of DNA is in issue; and has accepted similar numbers of instructions from prosecution and defence. He has contributed to humanitarian work in Kenya , Kosovo and Brazil—where he collaborates with colleagues investigating alleged human rights abuses of the military governments of 1964 to 1985.edit
The human KDM7 subfamily histone H3 Ne-methyl lysine demethylases PHF8 (KDM7B) and KIAA1718 (KDM7A) have different substrate selectivities and are linked to genetic diseases and cancer. We describe experimentally based computational... more
The human KDM7 subfamily histone H3 Ne-methyl lysine
demethylases PHF8 (KDM7B) and KIAA1718 (KDM7A) have different
substrate selectivities and are linked to genetic diseases and cancer.
We describe experimentally based computational studies revealing
that flexibility of the region linking the PHD finger and JmjC
domains in PHF8 and KIAA1718 regulates inter-domain interactions,
the nature of correlated motions, and ultimately H3 binding and
demethylation site selectivity. F279S an X-linked mental retardation
mutation in PHF8 is involved in correlated motions with the iron
ligands and second sphere residues. The calculations reveal key roles
of a flexible protein environment in productive formation of enzymesubstrate complexes and suggest targeting the flexible KDM7 linker region is of interest from a medicinal chemistry perspective.
demethylases PHF8 (KDM7B) and KIAA1718 (KDM7A) have different
substrate selectivities and are linked to genetic diseases and cancer.
We describe experimentally based computational studies revealing
that flexibility of the region linking the PHD finger and JmjC
domains in PHF8 and KIAA1718 regulates inter-domain interactions,
the nature of correlated motions, and ultimately H3 binding and
demethylation site selectivity. F279S an X-linked mental retardation
mutation in PHF8 is involved in correlated motions with the iron
ligands and second sphere residues. The calculations reveal key roles
of a flexible protein environment in productive formation of enzymesubstrate complexes and suggest targeting the flexible KDM7 linker region is of interest from a medicinal chemistry perspective.
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N-Methylation of DNA/RNA bases can be regulatory or damaging and is linked to diseases including cancer and genetic disorders. Bacterial AlkB and human FTO are DNA/RNA demethylases belonging to the Fe(II) and 2-oxoglutarate oxygenase... more
N-Methylation of DNA/RNA bases can be regulatory or damaging and is linked to diseases including cancer and genetic disorders. Bacterial AlkB and human FTO are DNA/RNA demethylases belonging to the Fe(II) and 2-oxoglutarate oxygenase superfamily. Modelling studies reveal conformational dynamics influence structure-function relationships of AlkB and FTO, e.g. why 1-methyladenine is a better substrate for AlkB than 6-methyladenine. Simulations show that the flexibility of the double stranded DNA substrate in AlkB influences correlated motions, including between the core jelly-roll fold and an active site loop involved in substrate binding. The FTO N-and C-terminal domains move in respect to one another in a manner likely important for substrate binding. Substitutions, including clinically observed ones, influencing catalysis contribute to the network of correlated motions in AlkB and FTO. Overall, the calculations highlight the importance of the overall protein environment and its flexibility to the geometry of the reactant complexes.
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Forensic science policy has been the subject of a series of judicial and parliamentary enquiries in the United Kingdom in recent decades. Forensic science research has been a recurrent theme in their reports, which have included... more
Forensic science policy has been the subject of a series of judicial and parliamentary enquiries in the United Kingdom in recent decades. Forensic science research has been a recurrent theme in their reports, which have included recommendations for research into the economics of forensic service provision; for the development of expertise and centres of excellence; and for research to establish the validity of the forensic sciences. These recommendations reflect similar concerns expressed internationally—particularly in the United States. In the United Kingdom, however, the Forensic Science Service recently enjoyed a near monopoly in research, and limited research funding and activity in the Universities was exacerbated by the lack of visibility of forensic science in government audits of research quality. This study used established methods in evidence-based policy and research quality evaluation to analyse the range, quantity and quality of research submitted to the two most
recent audits – RAE 2008 and REF 2014. Strengths and weaknesses in the methods used are discussed, and the findings analysed in relation to wider research policy issues in forensic science. The study concludes that consolidating forensic science as a peer-science in the academy is essential in order to establish a virtuous circle that will sustain research in the discipline—and address wider policy and socio-economic questions that persistently trouble the field.
recent audits – RAE 2008 and REF 2014. Strengths and weaknesses in the methods used are discussed, and the findings analysed in relation to wider research policy issues in forensic science. The study concludes that consolidating forensic science as a peer-science in the academy is essential in order to establish a virtuous circle that will sustain research in the discipline—and address wider policy and socio-economic questions that persistently trouble the field.
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Validation of a standard forensic anthropology examination protocol by measurement of applicability and reliability on exhumed and archive samples of known biological attribution. Forensic Science International in press.. Validation of a... more
Validation of a standard forensic anthropology examination protocol by measurement of applicability and reliability on exhumed and archive samples of known biological attribution. Forensic Science International in press.. Validation of a standard forensic anthropology examination protocol by measurement of applicability and reliability on exhumed and archive samples of known biological attribution. Forensic Science International in press.
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Exhumation may be defined as the legally sanctioned excavation and recovery of the remains of lawfully buried or – occasionally – cremated individuals, as distinct from forensic excavations of clandestinely buried remains conducted as... more
Exhumation may be defined as the legally sanctioned excavation and recovery of the remains of lawfully buried or – occasionally – cremated individuals, as distinct from forensic excavations of clandestinely buried remains conducted as part of a criminal investigation and from unlawful disinterment of human remains,commonly referred to as ‘bodysnatching’. The aim of this article is to review the role of exhumation – so defined – in the activities of CEMEL, the Medico-Legal
Centre of the Ribeirão Preto Medical School-University of São Paulo, in international, regional and local collaborations. Exhumations form part of routine forensic anthropology casework; scientific research in physical and forensic anthropology; and forensic casework conducted in collaboration with the Brazilian Federal Police; and are carried out as part of humanitarian investigations into deaths associated with the civil–military dictatorship of 1964 to 1985. This article aims to offer
a non-technical summary – with reference to international comparative information – of the role of exhumation in investigative and scientific work and to discuss developments in their historical and political context.
Centre of the Ribeirão Preto Medical School-University of São Paulo, in international, regional and local collaborations. Exhumations form part of routine forensic anthropology casework; scientific research in physical and forensic anthropology; and forensic casework conducted in collaboration with the Brazilian Federal Police; and are carried out as part of humanitarian investigations into deaths associated with the civil–military dictatorship of 1964 to 1985. This article aims to offer
a non-technical summary – with reference to international comparative information – of the role of exhumation in investigative and scientific work and to discuss developments in their historical and political context.
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Truth commissions are widely recognised tools used in negotiation following political repression. Their work may be underpinned by formal scientific investigation of human remains. This paper presents an analysis of the role of forensic... more
Truth commissions are widely recognised tools used in negotiation following political repression. Their work may be underpinned by formal scientific investigation of human remains. This paper presents an analysis of the role of forensic investigations in the transition to democracy following the Brazilian military governments of 1964-1985. It considers practices during the dictatorship and in the period following, making reference to analyses of truth commission work in jurisdictions other than Brazil, including those in which the investigation of clandestine burials has taken place. Attempts to conceal the fate of victims during the dictatorship and of democratic governments to investigate them are described. Despite various initiatives since the end of the military government, many victims remain unidentified. In Brazil, as elsewhere, forensic investigations are susceptible to political and social influences, leading to a situation in which relatives struggle to obtain meaningful restitution and have little trust in the transitional justice process.
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There is a perception in forensic anthropology that anthropometric methods are less subjective, and have lower intra and inter observer error rates compared with more subjective classificatory or anthroposcopic approaches. Anthropometric... more
There is a perception in forensic anthropology that anthropometric methods are less subjective, and have lower intra and inter observer error rates compared with more subjective classificatory or anthroposcopic approaches. Anthropometric methods have risks of execution errors, however, and may be laborious and time-consuming. Heterogeneous or less than homogeneous samples—such as in cases of intensive admixture—yield equally heterogeneous results. This study is an evaluation of the efficiency and effectiveness of an anthropometric method of sex estimation from the mastoid process triangle (porion, asterion and mastoidale), as described by Paiva & Segre and Kemkes & Göbel. Of 74 skulls selected from the CEMEL/FMRP-USP collection, 28 were excluded due to the impossibility of execution of the method. The remaining 46 skulls were measured three times and the results compared with each other, as well as with the assignments based on the classifications used in the LAF/CEMEL protocol. In addition to the high number of exclusions due to impossibility of execution of the method, and the need for technical refinements to avoid intra-observer errors, the results obtained contrasted with those obtained by Paiva & Segre in 60.9% of cases. Reduction of observer errors over time and with technical refinement led to the anthropometric method increasing in efficiency. It was not as effective in estimating the sex of the skulls in the heterogeneous admixed sample compared to the anthroposcopic methods, indicating that these are more useful on samples of this kind.
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The London Riots of August 2011 were notable for the prominence of CCTV images of offenders in news and social media, as well as in investigation, prosecution and conviction. The Metropolitan Police Service relied on specialist units that... more
The London Riots of August 2011 were notable for the prominence of CCTV images of offenders in news and social media, as well as in investigation, prosecution and conviction. The Metropolitan Police Service relied on specialist units that had in fact been established in the five years prior to the riots, which had been tasked with acting systematically upon CCTV image evidence: a procedural approach deemed so effective it had been termed the ‘Third Forensics’. This article discusses the significance of this claim and its implications for the justice system. The use of images in the investigations of the riots was highly effective, suggesting claims for substantially improved impact in investigation and prosecution are valid, and earlier scepticism regarding both utility and surveillance society agendas in public area CCTV studies was justified. Systematic procedural use of CCTV footage is not new, however, as demonstrated following riots in Vancouver, Canada, and earlier in Bradford, UK. Furthermore, identification in the ‘Third Forensics’ is eyewitness recognition, not scientifically or technologically comparable to fingerprints or DNA. The article suggests this difference affects risks of prejudice and miscarriages of justice, and the ‘profiling’ of individuals and social categories images appear to represent. The article concludes that while forensic investigation of CCTV images may not meet scientific criteria of a third forensic discipline, it does define a nascent development in police investigation where improvements in procedure have combined with proliferating CCTV systems and social media. This has led to a novel set of circumstances, which raises a number of unexplored issues of such significance that ‘Third Forensics’ is a suitable term to use to define them.
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In Approaching Utility in Forensic Anthropology, Evison, Francisco, and Guimarães (2012) propose an attrition model for the study of the impact of forensic anthropology in the justice system and consider wider implications for crime... more
In Approaching Utility in Forensic Anthropology, Evison, Francisco, and Guimarães (2012) propose an attrition model for the study of the impact of forensic anthropology in the justice system and consider wider implications for crime prevention and public health and safety. In this short supplementary article, brief illustrations of case findings are offered to demonstrate their significance in case progression—or conversions—in the investigative and prosecutorial process. The examples, it is suggested, support the specific arguments for improved communication and integration, feedback on evidential reliability, and tailoring of research and education to reflect caseload proposed via the attrition model, as well as policy advances that would improve efficacy in public health and safety.
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Analysis of genetically-based variation in human populations has been possible for nearly a century. Recently, DNA sequence-based methods have begun to replace protein-based methods leading to a higher resolution, but more complex... more
Analysis of genetically-based variation in human populations has been possible for nearly a century. Recently, DNA sequence-based methods have begun to replace protein-based methods leading to a higher resolution, but more complex results. Patterns of gene distribution may be established with statistical reliability, but understanding them in terms of history is a process of interpretation; multi-disciplinary research is essential. A brief synopsis of the Holocene in Britain is presented, based on the genetic data , but with reference to archaeology, palaeoecology, ethnology and linguistics. The genetic history of Britain is a Holocene history. Patterns of gene distributions can be seen as the consequence of social processes and of selection. The major events are: the reoccupation of Britain in the Late Upper Palaeolithic/Early Mesolithic (c. 10,000–7,500 bp), social and demographic development during the Mesolithic (7,500–6,000 bp), and the Mesolithic-Neolithic transition (6,000–4,000 bp). Interpretations of the transition based on social interaction, intermarriage and minor genetic input are most consistent with the broad evidence. An extreme “indigenist” position is not supported.
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This chapter begins with a brief overview of Brazil's somewhat hectic past and some key developments in legislation that have led to the rather incongruous state of forensic archaeology in a country whose economy is ranked the world's... more
This chapter begins with a brief overview of Brazil's somewhat hectic past and some key developments in legislation that have led to the rather incongruous state of forensic archaeology in a country whose economy is ranked the world's sixth largest and which has been chosen to host major sporting events such as the FIFA World Cup in 2014 and the Olympic Games in 2016. It discusses the contemporary situation in forensic archaeology in Brazil and follows with a reference to illustrative examples. The close interface between forensic archaeology and anthropology in Brazil makes both areas almost indistinguishable. Contemporary practice does recognise that forensic archaeology and anthropology represent more than excavation and osteology. The wider significance of forensic archaeology and anthropology to the rule of law and the safeguarding of human rights is of contemporary as well as historical importance, in Brazil as it is elsewhere.