SAD

This review paper presents an amplification of the suffocation false alarm theory (SFA) of spontaneous panic [Klein DF (1993). False suffocation alarms, spontaneous panics, and related conditions. An integrative hypothesis. Arch Gen Psychiatry; 50:306-17.]. SFA postulates the existence of an evolved physiologic suffocation alarm system that monitors information about potential suffocation. Panic attacks maladaptively occur when the alarm is erroneously triggered. That panic is distinct from Cannon's emergency fear response and Selye's General Alarm Syndrome is shown by the prominence of intense air hunger during these attacks. Further, panic sufferers have chronic sighing abnormalities outside of the acute attack. Another basic physiologic distinction between fear and panic is the counter-intuitive lack of hypothalamic-pituitary-adrenal (HPA) activation in panic. Understanding panic as provoked by indicators of potential suffocation, such as fluctuations in pCO(2) and brain ...

This article investigates whether the Nepalese stock market is efficient in weak form with respect to economically neutral behavioural variables. Simple OLS technique with White’s heteroskedasticity-corrected standard errors is used to test the relationship between stock returns and economically neutral behavioural variables represented by weather (cloud cover and temperature) and biorhythms (seasonal affective disorder). The findings indicate the existence of weak-form efficiency in the market for “temperature” and “seasonal affective disorder” but not for the “cloud cover”. These findings are not consistent to those of results documented for developed and emerging stock markets.

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The involvement of chronobiological mechanisms in the antidepressant response to such non-drug treatments as bright light, physical exercise and sleep deprivation still remain to be clarified. We compare the efficacy of several treatment strategies for seasonal and non-seasonal depression and discuss possible the contribution of chronobiological and psychological mechanisms in antidepressant response. The therapeutic effects were tested at the medical academic hospital near Novosibirsk (55 degrees North) in 138 subjects, either with winter depression or with non-seasonal depression or without depression (n = 41, 64 and 33, respectively). One-week monotreatments were either 2-hour 2500 lux cool-white incandescent light from 14:00 (n = 9, 9, 9, respectively) or 1-hour physical exercise from 13:00 (n = 9, 9, 9, respectively). One-week combined treatments included a night of total sleep deprivation followed by either 2-hour bright light from 14:00 (n = 8, 12, 0, respectively) or 1-hour physical exercise either under ordinary room light from 13:00 (n = 0, 12, 0, respectively) or under bright light from 12:00 (n = 5, 11, 0, respectively). The results indicate that, in subjects left without antidepressant treatment for a week (n = 10, 11, and 15, respectively), the 21-item Hamilton Depression Rating Scale score did not change significantly. The beneficial effects of total sleep deprivation were similar in seasonal and non-seasonal depression. The seasonals exhibited better response to bright light compared to non-seasonals. After sleep deprivation the substantial further improvements were produced by either lighting or exercising. Compared to the patients exercising under ordinary room light, the patients exercising under bright light did not gain an additional benefit. In general, winter depression was well-treated with either exercise or light, while the most promising treatment for non-seasonal depression was physical exercise combined with sleep deprivation. Bright light or physical exercise administered in the middle of the day were not less favorable compared to the treatments in the morning hours, although it is unlikely that they considerably challenged patient's chronobiology. It was concluded that the placebo effect would account for a large portion of clinical response to open non-pharmacological treatments. Therapeutic hops and visibility of such treatments would explain their high antidepressant efficacy in comparison with pharmacological trials applying a double blind cross-over design. In particular, the excellent response of patients with winter depression to light therapy might be related to their tendency to attribute a high symbolic value to bright light and associate their bad mood with a dark season.

Single-wavelength anomalous diffraction (SAD), multiwavelength anomalous diffraction (MAD) and single isomorphous replacement with anomalous scattering (SIRAS) phasing at ultra-high X-ray energy, 55 keV, are used successfully to determine a high-quality and high-resolution experimental electronic density map of hen egg-white lysozyme, a model protein. Several combinations, between single- and three-wavelength, with native data were exploited to demonstrate that standard phasing procedures with standard equipment and software can successfully be applied to three-dimensional crystal structure determination of a macromolecule, even at these very short wavelengths. For the first time, a high-quality three-dimensional molecular structure is reported from SAD phasing with ultra-high-energy X-rays. The quality of the crystallographic data and the experimental electron density maps meet current standards. The 2.7% anomalous signal from three Ho atoms, at the HoKedge, was sufficient to obtai...

Authors' Note Portions of this chapter were presented in a poster at the meeting of the International Society for Research on Emotions in Cuenca, Spain, in July 2002. We thank Randy Cornelius, Ursula Hess, and Pierre Philippot for their valuable comments on the manuscript. We also thank the undergraduate research assistants involved in collecting data: Susie Balazik, Maegan Dillman, Traci Lynn Frye, Lauren Kleha, and Dan Petrosky. We are grateful to Alice Eagly for providing access to her data on national stereotypes. Correspondence regarding this chapter should be addressed to Leah R. Warner, Department of Psychology, The Pennsylvania State University, University Park, PA 16802. Email: lrw138@psu.edu. Cell phones. You never know what news a call might bring. And in a public place it can be difficult to get a handle on the roller-coaster of emotions that ensues. Chris is upset. News of the divorce is surprising, yet not totally unexpected. Making matters worse, the phone call comes at a restaurant while Chris sits with friends at the table, surrounded by a roomful of strangers. The news is too much. And then it happens – along with the growing anger, tears well up in Chris's eyes. Adults' tears can be powerful elicitors of concern and sympathy. Tears can also elicit scorn or suspicion regarding the crying person's motives. Crying prompts others to pay attention, which makes tears a powerful form of persuasion.

2007 Andres Felipe Granados / Jorge Ivan Marin H. DETECCIÓN DE FLUJO VEHICULAR BASADO EN VISIÓN ARTIFICIAL Scientia Et Technica, agosto, año/vol. XIII, número 035 Universidad Tecnológica de Pereira Pereira, Colombia pp. 163-168 ... Red de Revistas Científicas de América ...

INTRODUCTION: Social anxiety disorder (SAD) is a condition characterised by fears of social interaction and performance situations. SAD may be related to a dysregulation or hyperactivity of cortico-limbic circuitry. This is the first voxel-based whole brain study comparing resting function in SAD to a normal control group. METHODS: Resting perfusion in adult subjects with generalised SAD was compared with healthy adult volunteers using Statistical Parametric Mapping (SPM). In subjects with SAD, correlations were also sought ...

This paper presents a multiagent system that can process stereoscopic images and detect people with a stereo camera. In the first of two phases, the system creates a model of the environment using a disparity map. It can be constructed in real time, even if there are moving objects present in the area (such as people passing by). In the second phase, the system is able to detect people by combining a series of novel techniques. A multi-agent system (MAS) is used to deal with the problem. The system is based on cooperative and distributed mechanisms and was tested under different conditions and environments.