Conforms to Regulation (EC) No.

1907/2006 (REACH), Annex II

Macropoxy 646 Multi-Purpose Epoxy - Additive
M646A

SAFETY DATA SHEET

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1 Product identifier
Product name : Macropoxy 646 Multi-Purpose Epoxy - Additive
Product code : M646A

1.2 Relevant identified uses of the substance or mixture and uses advised against
Material uses : Paint or paint related material.
: Industrial use only.

1.3 Details of the supplier of the safety data

sheet
Sherwin-Williams Protective & Marine
Tower Works
Kestor Street
Bolton
BL2 2AL
United Kingdom
+44 (0) 1204 521771

The Sherwin-Williams Company

Inver France SAS
2 Rue Jean Revaus - BP 80088 - 79102
Thouars CEDEX
France

e-mail address of person : hse.pm.emea@sherwin.com

responsible for this SDS

1.4 Emergency telephone number

National advisory body/Poison Center
Telephone number : 070 245 245
Supplier
Telephone number : +(44)-870-8200 418
Hours of operation : Emergency contact available 24 hours a day

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture
Product definition : Mixture
Classification according to Regulation (EC) No. 1272/2008 [CLP/GHS]
Flam. Liq. 3, H226
Skin Irrit. 2, H315
Eye Irrit. 2, H319
Skin Sens. 1, H317
STOT RE 1, H372
Aquatic Chronic 3, H412
The product is classified as hazardous according to Regulation (EC) 1272/2008 as amended.
See Section 16 for the full text of the H statements declared above.

Date of issue/Date of revision : 25, Jun, 2021 Date of previous issue : 13, Apr, 2021 Version : 13.01 1/16
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II
Macropoxy 646 Multi-Purpose Epoxy - Additive
M646A

SECTION 2: Hazards identification

See Section 11 for more detailed information on health effects and symptoms.

2.2 Label elements

Hazard pictograms :

Signal word : Danger

Hazard statements : Flammable liquid and vapor.
Causes skin irritation.
May cause an allergic skin reaction.
Causes serious eye irritation.
Causes damage to organs through prolonged or repeated exposure.
Harmful to aquatic life with long lasting effects.
Precautionary statements
Prevention : Wear protective gloves. Wear eye or face protection. Keep away from heat, hot
surfaces, sparks, open flames and other ignition sources. No smoking. Avoid
release to the environment. Do not breathe vapor. Do not eat, drink or smoke
when using this product. Wash thoroughly after handling.
Response : Not applicable.
Storage : Not applicable.
Disposal : Not applicable.
Hazardous ingredients : Crystalline Silica, respirable powder
Epoxy Polymer
Supplemental label : Contains epoxy constituents. May produce an allergic reaction. FOR INDUSTRIAL
elements USE ONLY
Annex XVII - Restrictions : Not applicable.
on the manufacture,
placing on the market and
use of certain dangerous
substances, mixtures and
articles
Special packaging requirements
Not applicable.

2.3 Other hazards

This mixture does not contain any substances that are assessed to be a PBT or a
vPvB.
Other hazards which do : None known.
not result in classification

SECTION 3: Composition/information on ingredients

3.2 Mixture :

Product/ingredient Identifiers % Regulation (EC) No. 1272/2008 [CLP] Type

name

Date of issue/Date of revision : 25, Jun, 2021 Date of previous issue : 13, Apr, 2021 Version : 13.01 2/16
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II
Macropoxy 646 Multi-Purpose Epoxy - Additive
M646A

SECTION 3: Composition/information on ingredients

Crystalline Silica, EC: 238-878-4 ≥50 - ≤75 STOT RE 1, H372 (inhalation) [1] [2]
respirable powder CAS: 14808-60-7
Epoxy Polymer REACH #: ≥10 - <25 Skin Irrit. 2, H315 [1]
01-2119456619-26 Eye Irrit. 2, H319
EC: 216-823-5 Skin Sens. 1, H317
CAS: 1675-54-3 Aquatic Chronic 2, H411
Index: 603-073-00-2
Methyl Isobutyl Ketone REACH #: ≤10 Flam. Liq. 2, H225 [1] [2]
01-2119473980-30 Acute Tox. 4, H332
EC: 203-550-1 Eye Irrit. 2, H319
CAS: 108-10-1 STOT SE 3, H335
Index: 606-004-00-4 EUH066
Xylene, mixed isomers REACH #: ≤3 Flam. Liq. 3, H226 [1] [2]
01-2119488216-32 Acute Tox. 4, H312
EC: 215-535-7 Acute Tox. 4, H332
CAS: 1330-20-7 Skin Irrit. 2, H315
Index: 601-022-00-9 Eye Irrit. 2, H319
STOT SE 3, H335
STOT RE 2, H373
Asp. Tox. 1, H304
See Section 16 for the full text of the H
statements declared above.
There are no additional ingredients present which, within the current knowledge of the supplier and in the
concentrations applicable, are classified as hazardous to health or the environment, are PBTs or vPvBs or have been
assigned a workplace exposure limit and hence require reporting in this section.
Type
[1] Substance classified with a health or environmental hazard
[2] Substance with a workplace exposure limit
[3] Substance meets the criteria for PBT according to Regulation (EC) No. 1907/2006, Annex XIII
[4] Substance meets the criteria for vPvB according to Regulation (EC) No. 1907/2006, Annex XIII
[5] Substance of equivalent concern
[6] Additional disclosure due to company policy
Occupational exposure limits, if available, are listed in Section 8.
SECTION 4: First aid measures
4.1 Description of first aid measures
General : In all cases of doubt, or when symptoms persist, seek medical attention. Never give
anything by mouth to an unconscious person. If unconscious, place in recovery
position and seek medical advice.
Eye contact : Remove contact lenses, irrigate copiously with clean, fresh water, holding the
eyelids apart for at least 10 minutes and seek immediate medical advice.
Inhalation : Remove to fresh air. Keep person warm and at rest. If not breathing, if breathing is
irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by
trained personnel.
Skin contact : Remove contaminated clothing and shoes. Wash skin thoroughly with soap and
water or use recognized skin cleanser. Do NOT use solvents or thinners.
Ingestion : If swallowed, seek medical advice immediately and show this container or label.
Keep person warm and at rest. Do NOT induce vomiting.
Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training. It
may be dangerous to the person providing aid to give mouth-to-mouth resuscitation.
Wash contaminated clothing thoroughly with water before removing it, or wear
gloves.

4.2 Most important symptoms and effects, both acute and delayed

Date of issue/Date of revision : 25, Jun, 2021 Date of previous issue : 13, Apr, 2021 Version : 13.01 3/16
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II
Macropoxy 646 Multi-Purpose Epoxy - Additive
M646A

SECTION 4: First aid measures

There are no data available on the mixture itself. Procedure used to derive the classification according to Regulation
(EC) No. 1272/2008 [CLP/GHS]. See Sections 2 and 3 for details.

Exposure to component solvent vapor concentrations in excess of the stated occupational exposure limit may result in
adverse health effects such as mucous membrane and respiratory system irritation and adverse effects on the
kidneys, liver and central nervous system. Symptoms and signs include headache, dizziness, fatigue, muscular
weakness, drowsiness and, in extreme cases, loss of consciousness.
Solvents may cause some of the above effects by absorption through the skin. Repeated or prolonged contact with
the mixture may cause removal of natural fat from the skin, resulting in non-allergic contact dermatitis and absorption
through the skin.
If splashed in the eyes, the liquid may cause irritation and reversible damage.
Ingestion may cause nausea, diarrhea and vomiting.
This takes into account, where known, delayed and immediate effects and also chronic effects of components from
short-term and long-term exposure by oral, inhalation and dermal routes of exposure and eye contact.

Based on the properties of the epoxy constituent(s) and considering toxicological data on similar mixtures, this
mixture may be a skin sensitizer and an irritant. It contains low-molecular weight epoxy constituents which are
irritating to eyes, mucous membranes and skin. Repeated skin contact may lead to irritation and to sensitization,
possibly with cross-sensitization to other epoxies. Skin contact with the mixture and exposure to spray, mist and
vapors should be avoided.

Contains bis-[4-(2,3-epoxipropoxi)phenyl]propane. May produce an allergic reaction.

4.3 Indication of any immediate medical attention and special treatment needed
Notes to physician : Treat symptomatically. Contact poison treatment specialist immediately if large
quantities have been ingested or inhaled.
Specific treatments : No specific treatment.

See toxicological information (Section 11)

SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing : Recommended: alcohol-resistant foam, carbon dioxide, powders.
media
Unsuitable extinguishing : Do not use water jet.
media

5.2 Special hazards arising from the substance or mixture

Hazards from the : Fire will produce dense black smoke. Exposure to decomposition products may
substance or mixture cause a health hazard.
Hazardous combustion : Decomposition products may include the following materials: carbon monoxide,
products carbon dioxide, smoke, oxides of nitrogen.

5.3 Advice for firefighters

Special protective actions : Cool closed containers exposed to fire with water. Do not release runoff from fire to
for fire-fighters drains or watercourses.
Special protective : Fire-fighters should wear positive pressure self-contained breathing apparatus
equipment for fire-fighters (SCBA) and full turnout gear.

Date of issue/Date of revision : 25, Jun, 2021 Date of previous issue : 13, Apr, 2021 Version : 13.01 4/16
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II
Macropoxy 646 Multi-Purpose Epoxy - Additive
M646A

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures
For non-emergency : Exclude sources of ignition and ventilate the area. Avoid breathing vapor or mist.
personnel Refer to protective measures listed in sections 7 and 8.
Keep unnecessary and unprotected personnel from entering.
For emergency responders : If specialized clothing is required to deal with the spillage, take note of any
information in Section 8 on suitable and unsuitable materials. See also the
information in "For non-emergency personnel".

6.2 Environmental : Do not allow to enter drains or watercourses. If the product contaminates lakes,
precautions rivers, or sewers, inform the appropriate authorities in accordance with local
regulations.

6.3 Methods and materials : Contain and collect spillage with non-combustible, absorbent material e.g. sand,
for containment and earth, vermiculite or diatomaceous earth and place in container for disposal
cleaning up according to local regulations (see Section 13). Preferably clean with a detergent.
Avoid using solvents.
6.4 Reference to other : See Section 1 for emergency contact information.
sections See Section 8 for information on appropriate personal protective equipment.
See Section 13 for additional waste treatment information.
SECTION 7: Handling and storage
The information in this section contains generic advice and guidance. The list of Identified Uses in Section 1 should be
consulted for any available use-specific information provided in the Exposure Scenario(s).
7.1 Precautions for safe : Prevent the creation of flammable or explosive concentrations of vapors in air and
handling avoid vapor concentrations higher than the occupational exposure limits.
In addition, the product should only be used in areas from which all naked lights and
other sources of ignition have been excluded. Electrical equipment should be
protected to the appropriate standard.
Mixture may charge electrostatically: always use earthing leads when transferring
from one container to another.
Operators should wear antistatic footwear and clothing and floors should be of the
conducting type.
Keep away from heat, sparks and flame. No sparking tools should be used.
Avoid contact with skin and eyes. Avoid the inhalation of dust, particulates, spray or
mist arising from the application of this mixture. Avoid inhalation of dust from
sanding.
Eating, drinking and smoking should be prohibited in areas where this material is
handled, stored and processed.
Put on appropriate personal protective equipment (see Section 8).
Never use pressure to empty. Container is not a pressure vessel.
Always keep in containers made from the same material as the original one.
Comply with the health and safety at work laws.
Do not allow to enter drains or watercourses.
Information on fire and explosion protection
Vapors are heavier than air and may spread along floors. Vapors may form
explosive mixtures with air.

When operators, whether spraying or not, have to work inside the spray booth,
ventilation is unlikely to be sufficient to control particulates and solvent vapors in all
cases. In such circumstances, they should wear a compressed-air-fed respirator
during the spraying process and until the particulate and solvent vapor
concentrations have fallen below the exposure limits.

Date of issue/Date of revision : 25, Jun, 2021 Date of previous issue : 13, Apr, 2021 Version : 13.01 5/16
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II
Macropoxy 646 Multi-Purpose Epoxy - Additive
M646A

SECTION 7: Handling and storage

7.2 Conditions for safe : Store in accordance with local regulations.
storage, including any Notes on joint storage
incompatibilities Keep away from: oxidizing agents, strong alkalis, strong acids.
Additional information on storage conditions
Observe label precautions. Store in a dry, cool and well-ventilated area. Keep away
from heat and direct sunlight. Keep away from sources of ignition. No smoking.
Prevent unauthorized access. Containers that have been opened must be carefully
resealed and kept upright to prevent leakage.
Contaminated absorbent material may pose the same hazard as the spilled product.
Store in closed original container at temperatures between 5°C and 25°C.

7.3 Specific end use(s)

Recommendations : Not available.
Industrial sector specific : Not available.
solutions
Good housekeeping standards, regular safe removal of waste materials and regular maintenance of spray booth
filters will minimise the risks of spontaneous combustion and other fire hazards.
Before use of this material please refer to the Exposure Scenario(s) if attached for the specific end use,
control measures and additional PPE considerations.
SECTION 8: Exposure controls/personal protection
The information in this section contains generic advice and guidance. The list of Identified Uses in Section 1 should be
consulted for any available use-specific information provided in the Exposure Scenario(s).
8.1 Control parameters
Occupational exposure limits
Product/ingredient name Exposure limit values

Crystalline Silica, respirable powder Limit values (Belgium, 1/2020).

TWA: 0.1 mg/m³ 8 hours. Form: respirable dust
Methyl Isobutyl Ketone Limit values (Belgium, 1/2020).
TWA: 20 ppm 8 hours.
TWA: 83 mg/m³ 8 hours.
STEL: 50 ppm 15 minutes.
STEL: 208 mg/m³ 15 minutes.
Xylene, mixed isomers Limit values (Belgium, 1/2020). Absorbed through skin.
TWA: 50 ppm 8 hours.
TWA: 221 mg/m³ 8 hours.
STEL: 100 ppm 15 minutes.
STEL: 442 mg/m³ 15 minutes.

Recommended monitoring : If this product contains ingredients with exposure limits, personal, workplace
procedures atmosphere or biological monitoring may be required to determine the effectiveness
of the ventilation or other control measures and/or the necessity to use respiratory
protective equipment. Reference should be made to monitoring standards, such as
the following: European Standard EN 689 (Workplace atmospheres - Guidance for
the assessment of exposure by inhalation to chemical agents for comparison with
limit values and measurement strategy) European Standard EN 14042 (Workplace
atmospheres - Guide for the application and use of procedures for the assessment
of exposure to chemical and biological agents) European Standard EN 482
(Workplace atmospheres - General requirements for the performance of procedures
for the measurement of chemical agents) Reference to national guidance
documents for methods for the determination of hazardous substances will also be
required.
: Regular monitoring of all work areas should be carried out at all times, including
areas that may not be equally ventilated.
DNELs/DMELs
Date of issue/Date of revision : 25, Jun, 2021 Date of previous issue : 13, Apr, 2021 Version : 13.01 6/16
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II
Macropoxy 646 Multi-Purpose Epoxy - Additive
M646A

SECTION 8: Exposure controls/personal protection

Product/ingredient name Type Exposure Value Population Effects
Methyl Isobutyl Ketone DNEL Short term 208 mg/m³ Workers Systemic
Inhalation
DNEL Short term 208 mg/m³ Workers Local
Inhalation
DNEL Long term 83 mg/m³ Workers Systemic
Inhalation
DNEL Long term 83 mg/m³ Workers Local
Inhalation
DNEL Long term Dermal 11.8 mg/ Workers Systemic
kg bw/day
DNEL Short term 155.2 mg/ General Systemic
Inhalation m³ population
[Consumers]
DNEL Short term 155.2 mg/ General Local
Inhalation m³ population
[Consumers]
DNEL Long term 14.7 mg/m³ General Systemic
Inhalation population
[Consumers]
DNEL Long term 14.7 mg/m³ General Local
Inhalation population
[Consumers]
DNEL Long term Dermal 4.2 mg/kg General Systemic
bw/day population
[Consumers]
DNEL Long term Oral 4.2 mg/kg General Systemic
bw/day population
[Consumers]
Xylene, mixed isomers DNEL Long term Dermal 180 mg/kg Workers Systemic
bw/day
DNEL Long term Dermal 108 mg/kg General Systemic
bw/day population
[Human via the
environment]
DNEL Long term 77 mg/m³ Workers Systemic
Inhalation
DNEL Short term 289 mg/m³ Workers Systemic
Inhalation
DNEL Short term 289 mg/m³ Workers Local
Inhalation
DNEL Long term 14.8 mg/m³ General Systemic
Inhalation population
[Human via the
environment]
DNEL Short term 174 mg/m³ General Systemic
Inhalation population
[Consumers]
DNEL Short term 174 mg/m³ General Local
Inhalation population
[Consumers]
PNECs

Date of issue/Date of revision : 25, Jun, 2021 Date of previous issue : 13, Apr, 2021 Version : 13.01 7/16
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II
Macropoxy 646 Multi-Purpose Epoxy - Additive
M646A

SECTION 8: Exposure controls/personal protection

Product/ingredient name Compartment Detail Value Method Detail
Methyl Isobutyl Ketone Fresh water 0.6 mg/l -
Marine water 0.06 mg/l -
Sewage Treatment 27.5 mg/l -
Plant
Fresh water sediment 8.27 mg/kg dwt -
Marine water sediment 0.83 mg/kg dwt -
Soil 1.3 mg/kg dwt -
Xylene, mixed isomers Fresh water 0.327 mg/l -
Marine water 0.327 mg/l -
Fresh water sediment 12.46 mg/l -
Sewage Treatment 6.58 mg/l -
Plant
Soil 2.31 mg/kg -
Marine water sediment 12.46 mg/l -

8.2 Exposure controls

Appropriate engineering : Provide adequate ventilation. Where reasonably practicable, this should be
controls achieved by the use of local exhaust ventilation and good general extraction. If
these are not sufficient to maintain concentrations of particulates and solvent vapors
below the OEL, suitable respiratory protection must be worn.
: Users are advised to consider national Occupational Exposure Limits or other
equivalent values.
Individual protection measures
Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period.
Appropriate techniques should be used to remove potentially contaminated clothing.
Contaminated work clothing should not be allowed out of the workplace. Wash
contaminated clothing before reusing. Ensure that eyewash stations and safety
showers are close to the workstation location.
Eye/face protection : Use safety eyewear designed to protect against splash of liquids.
Skin protection
Hand protection : Wear suitable gloves tested to EN374.
Gloves : Gloves for short term exposure/splash protection (less than 10 min.): Nitrile>0.12
mm
Gloves for splash protection need to be changed immediately when in contact with
chemicals.
Gloves for repeated or prolonged exposure (breakthrough time > 240 min.)
When the hazardous ingredients in Section 3 contain any of the following: Aromatic
solvents (Xylene, Toluene) or Aliphatic solvents or Mineral Oil use: Polyvinyl alcohol
(PVA) gloves 0.2-0.3 mm
Otherwise use: Butyl gloves >0.3 mm
For long term exposure or spills (breakthrough time >480 min.): Use PE laminated
gloves as under gloves
Due to many conditions (e.g. temperature, abrasion) the practical usage of a
chemical protective glove in practice may be much shorter than the permeation time
determined through testing.
The recommendation for the type or types of glove to use when handling this
product is based on information from the following source: Solvent resin
manufacturers and European Solvents Industry Group (ESIG)
There is no one glove material or combination of materials that will give unlimited
resistance to any individual or combination of chemicals.
The breakthrough time must be greater than the end use time of the product.
The instructions and information provided by the glove manufacturer on use,
storage, maintenance and replacement must be followed.
Gloves should be replaced regularly and if there is any sign of damage to the glove
material.
Always ensure that gloves are free from defects and that they are stored and used
Date of issue/Date of revision : 25, Jun, 2021 Date of previous issue : 13, Apr, 2021 Version : 13.01 8/16
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II
Macropoxy 646 Multi-Purpose Epoxy - Additive
M646A

SECTION 8: Exposure controls/personal protection

correctly.
The performance or effectiveness of the glove may be reduced by physical/chemical
damage and poor maintenance.
Barrier creams may help to protect the exposed areas of the skin but should not be
applied once exposure has occurred.
The user must check that the final choice of type of glove selected for handling this
product is the most appropriate and takes into account the particular conditions of
use, as included in the user's risk assessment.
Body protection : Personnel should wear antistatic clothing made of natural fibers or of high-
temperature-resistant synthetic fibers.
: Personal protective equipment for the body should be selected based on the task
being performed and the risks involved and should be approved by a specialist
before handling this product. When there is a risk of ignition from static electricity,
wear anti-static protective clothing. For the greatest protection from static
discharges, clothing should include anti-static overalls, boots and gloves. Refer to
European Standard EN 1149 for further information on material and design
requirements and test methods.
Other skin protection : Appropriate footwear and any additional skin protection measures should be
selected based on the task being performed and the risks involved and should be
approved by a specialist before handling this product.
Respiratory protection : Use a properly fitted, particulate filter respirator complying with an approved
standard if a risk assessment indicates this is necessary. Recommended: A2P2
(EN14387). Respirator selection must be based on known or anticipated exposure
levels, the hazards of the product and the safe working limits of the selected
respirator.
Environmental exposure : Do not allow to enter drains or watercourses.
controls
Before use of this material please refer to the Exposure Scenario(s) if attached for the specific end use,
control measures and additional PPE considerations. The information contained in this safety data sheet
does not constitute the user’s own assessment of workplace risks, as required by other health and safety
legislation. The provisions of the national health and safety at work regulations apply to the use of this
product at work.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
Appearance
Physical state : Liquid.
Color : Colorless to light yellow.
Odor : Solvent.
Odor threshold : Not Available (Not Tested).
pH : Not applicable.
Melting point/freezing point : Not relevant/applicable due to nature of the product.
Initial boiling point and : 113°C
boiling range
Flash point : Closed cup: 23°C [Pensky-Martens Closed Cup]
Evaporation rate : 1.62 (butyl acetate = 1)
Flammability (solid, gas) : Not relevant/applicable due to nature of the product.
Upper/lower flammability or : LEL: 1% (Xylene, mixed isomers)
explosive limits UEL: 7.5% (Methyl Isobutyl Ketone)
Vapor pressure : 2.1 kPa [at 20°C]
Vapor density : 3.45 [Air = 1]
Relative density : 1.61
Solubility(ies) : Not relevant/applicable due to nature of the product.

Date of issue/Date of revision : 25, Jun, 2021 Date of previous issue : 13, Apr, 2021 Version : 13.01 9/16
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II
Macropoxy 646 Multi-Purpose Epoxy - Additive
M646A

SECTION 9: Physical and chemical properties

Partition coefficient: n-octanol/ : Not relevant/applicable due to nature of the product.
water
Auto-ignition temperature : Not relevant/applicable due to nature of the product.
Decomposition temperature Not relevant/applicable due to nature of the product.
Viscosity : Kinematic (40°C): >0.205 cm2/s
Explosive properties : Under normal conditions of storage and use, hazardous reactions will not occur.
Oxidizing properties : Under normal conditions of storage and use, hazardous reactions will not occur.

SECTION 10: Stability and reactivity

10.1 Reactivity : No specific test data related to reactivity available for this product or its ingredients.

10.2 Chemical stability : Stable under recommended storage and handling conditions (see Section 7).

10.3 Possibility of : Under normal conditions of storage and use, hazardous reactions will not occur.
hazardous reactions

10.4 Conditions to avoid : When exposed to high temperatures may produce hazardous decomposition
products.

10.5 Incompatible materials : Keep away from the following materials to prevent strong exothermic reactions:
oxidizing agents, strong alkalis, strong acids.

10.6 Hazardous : Decomposition products may include the following materials: carbon monoxide,
decomposition products carbon dioxide, smoke, oxides of nitrogen.
Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL
PROTECTION for additional handling information and protection of employees.
SECTION 11: Toxicological information
11.1 Information on toxicological effects
There are no data available on the mixture itself. Procedure used to derive the classification according to Regulation
(EC) No. 1272/2008 [CLP/GHS]. See Sections 2 and 3 for details.

Exposure to component solvent vapor concentrations in excess of the stated occupational exposure limit may result in
adverse health effects such as mucous membrane and respiratory system irritation and adverse effects on the
kidneys, liver and central nervous system. Symptoms and signs include headache, dizziness, fatigue, muscular
weakness, drowsiness and, in extreme cases, loss of consciousness.
Solvents may cause some of the above effects by absorption through the skin. Repeated or prolonged contact with
the mixture may cause removal of natural fat from the skin, resulting in non-allergic contact dermatitis and absorption
through the skin.
If splashed in the eyes, the liquid may cause irritation and reversible damage.
Ingestion may cause nausea, diarrhea and vomiting.
This takes into account, where known, delayed and immediate effects and also chronic effects of components from
short-term and long-term exposure by oral, inhalation and dermal routes of exposure and eye contact.

Based on the properties of the epoxy constituent(s) and considering toxicological data on similar mixtures, this
mixture may be a skin sensitizer and an irritant. It contains low-molecular weight epoxy constituents which are
irritating to eyes, mucous membranes and skin. Repeated skin contact may lead to irritation and to sensitization,
possibly with cross-sensitization to other epoxies. Skin contact with the mixture and exposure to spray, mist and
vapors should be avoided.

Contains bis-[4-(2,3-epoxipropoxi)phenyl]propane. May produce an allergic reaction.

Acute toxicity

Date of issue/Date of revision : 25, Jun, 2021 Date of previous issue : 13, Apr, 2021 Version : 13.01 10/16
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II
Macropoxy 646 Multi-Purpose Epoxy - Additive
M646A

SECTION 11: Toxicological information

Product/ingredient name Result Species Dose Exposure
Epoxy Polymer LD50 Dermal Rabbit 20 g/kg -
Methyl Isobutyl Ketone LD50 Oral Rat 2080 mg/kg -
Xylene, mixed isomers LC50 Inhalation Gas. Rat 6700 ppm 4 hours
LD50 Oral Rat 4300 mg/kg -
Acute toxicity estimates
Route ATE value
Dermal 61055.31 mg/kg
Inhalation (gases) 371882.36 ppm
Inhalation (vapors) 114.56 mg/l
Irritation/Corrosion
Product/ingredient name Result Species Score Exposure Observation
Epoxy Polymer Eyes - Severe irritant Rabbit - 24 hours 2 -
mg
Skin - Mild irritant Rabbit - 500 mg -
Methyl Isobutyl Ketone Eyes - Moderate irritant Rabbit - 24 hours 100 -
uL
Eyes - Severe irritant Rabbit - 40 mg -
Skin - Mild irritant Rabbit - 24 hours 500 -
mg
Xylene, mixed isomers Eyes - Mild irritant Rabbit - 87 mg -
Eyes - Severe irritant Rabbit - 24 hours 5 -
mg
Skin - Mild irritant Rat - 8 hours 60 uL -
Skin - Moderate irritant Rabbit - 24 hours 500 -
mg
Skin - Moderate irritant Rabbit - 100 % -
Conclusion/Summary : Not available.
Sensitization
No data available

Conclusion/Summary : Not available.

Mutagenicity
No data available
Carcinogenicity
No data available
Reproductive toxicity
No data available
Teratogenicity
No data available
Specific target organ toxicity (single exposure)
Product/ingredient name Category Route of Target organs
exposure
Methyl Isobutyl Ketone Category 3 - Respiratory tract
irritation
Xylene, mixed isomers Category 3 - Respiratory tract
irritation
Specific target organ toxicity (repeated exposure)

Date of issue/Date of revision : 25, Jun, 2021 Date of previous issue : 13, Apr, 2021 Version : 13.01 11/16
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II
Macropoxy 646 Multi-Purpose Epoxy - Additive
M646A

SECTION 11: Toxicological information

Product/ingredient name Category Route of Target organs
exposure
Crystalline Silica, respirable powder Category 1 inhalation -
Xylene, mixed isomers Category 2 - -
Aspiration hazard
Product/ingredient name Result
Xylene, mixed isomers ASPIRATION HAZARD - Category 1

Other information : Not available.

SECTION 12: Ecological information
12.1 Toxicity
There are no data available on the mixture itself.
Do not allow to enter drains or watercourses.

Procedure used to derive the classification according to Regulation (EC) No. 1272/2008 [CLP/GHS]. See Sections 2
and 3 for details.
Product/ingredient name Result Species Exposure
Methyl Isobutyl Ketone Acute LC50 505000 µg/l Fresh water Fish - Pimephales promelas 96 hours
Chronic NOEC 78 mg/l Fresh water Daphnia - Daphnia magna 21 days
Chronic NOEC 168 mg/l Fresh water Fish - Pimephales promelas - 33 days
Embryo
Xylene, mixed isomers Acute LC50 8500 µg/l Marine water Crustaceans - Palaemonetes 48 hours
pugio
Acute LC50 13400 µg/l Fresh water Fish - Pimephales promelas 96 hours

12.2 Persistence and degradability

Product/ingredient name Test Result Dose Inoculum
No data available
Conclusion/Summary : Not available.
Product/ingredient name Aquatic half-life Photolysis Biodegradability
Methyl Isobutyl Ketone - - Readily
Xylene, mixed isomers - - Readily

12.3 Bioaccumulative potential

Product/ingredient name LogPow BCF Potential
Xylene, mixed isomers - 8.1 to 25.9 low

12.4 Mobility in soil

Soil/water partition : Not available.
coefficient (KOC)
Mobility : Not available.

12.5 Results of PBT and vPvB assessment

This mixture does not contain any substances that are assessed to be a PBT or a vPvB.

12.6 Other adverse effects : No known significant effects or critical hazards.

Date of issue/Date of revision : 25, Jun, 2021 Date of previous issue : 13, Apr, 2021 Version : 13.01 12/16
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II
Macropoxy 646 Multi-Purpose Epoxy - Additive
M646A

SECTION 12: Ecological information

: Avoid dispersal of spilled material and runoff and contact with soil, waterways,
drains and sewers.
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product
Methods of disposal : The generation of waste should be avoided or minimized wherever possible.
Disposal of this product, solutions and any by-products should at all times comply
with the requirements of environmental protection and waste disposal legislation
and any regional local authority requirements. Dispose of surplus and non-
recyclable products via a licensed waste disposal contractor. Waste should not be
disposed of untreated to the sewer unless fully compliant with the requirements of
all authorities with jurisdiction.
Hazardous waste : Yes.
European waste : waste paint and varnish containing organic solvents or other hazardous substances
catalogue (EWC) 08 01 11*
Disposal considerations : Do not allow to enter drains or watercourses.
Dispose of according to all federal, state and local applicable regulations.
If this product is mixed with other wastes, the original waste product code may no
longer apply and the appropriate code should be assigned.
For further information, contact your local waste authority.
Packaging
Methods of disposal : The generation of waste should be avoided or minimized wherever possible. Waste
packaging should be recycled. Incineration or landfill should only be considered
when recycling is not feasible.
Disposal considerations : Using information provided in this safety data sheet, advice should be obtained from
the relevant waste authority on the classification of empty containers. Empty
containers must be scrapped or reconditioned. Dispose of containers contaminated
by the product in accordance with local or national legal provisions.
European waste : packaging containing residues of or contaminated by hazardous substances 15 01
catalogue (EWC) 10*
Special precautions : This material and its container must be disposed of in a safe way. Care should be
taken when handling emptied containers that have not been cleaned or rinsed out.
Empty containers or liners may retain some product residues. Vapor from product
residues may create a highly flammable or explosive atmosphere inside the
container. Do not cut, weld or grind used containers unless they have been cleaned
thoroughly internally. Avoid dispersal of spilled material and runoff and contact with
soil, waterways, drains and sewers.
SECTION 14: Transport information
ADR/RID IMDG IATA
14.1 UN number UN1263 UN1263 UN1263

14.2 UN proper PAINT PAINT PAINT

shipping name
14.3 Transport 3 3 3
Hazard Class(es)/
Label(s)

14.4 Packing III III III

group

Date of issue/Date of revision : 25, Jun, 2021 Date of previous issue : 13, Apr, 2021 Version : 13.01 13/16
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II
Macropoxy 646 Multi-Purpose Epoxy - Additive
M646A

SECTION 14: Transport information

14.5 No. No. No.
Environmental
hazards
Additional Tunnel code D/E Emergency schedules F-E, -
information S-E

14.6 Special precautions for : Transport within user’s premises: always transport in closed containers that are
user upright and secure. Ensure that persons transporting the product know what to do in
the event of an accident or spillage.

14.7 Transport in bulk : Not applicable.

according to IMO
instruments
Multi-modal shipping descriptions are provided for informational purposes and do not consider container
sizes. The presence of a shipping description for a particular mode of transport (sea, air, etc.), does not
indicate that the product is packaged suitably for that mode of transport. All packaging must be reviewed for
suitability prior to shipment, and compliance with the applicable regulations is the sole responsibility of the
person offering the product for transport. People loading and unloading dangerous goods must be trained on
all of the risks deriving from the substances and on all actions in case of emergency situations.
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
EU Regulation (EC) No. 1907/2006 (REACH)
Annex XIV - List of substances subject to authorization
Annex XIV
None of the components are listed.
Annex XVII - Restrictions : Not applicable.
on the manufacture,
placing on the market
and use of certain
dangerous substances,
mixtures and articles
Other EU regulations
VOC content (2010/75/EU) : 12.1 w/w
196 g/l

Seveso Directive
This product may add to the calculation for determining whether a site is within the scope of the Seveso Directive on
major accident hazards.
National regulations

15.2 Chemical Safety : No Chemical Safety Assessment has been carried out.
Assessment

Date of issue/Date of revision : 25, Jun, 2021 Date of previous issue : 13, Apr, 2021 Version : 13.01 14/16
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II
Macropoxy 646 Multi-Purpose Epoxy - Additive
M646A

SECTION 16: Other information

Indicates information that has changed from previously issued version.
Abbreviations and : ATE = Acute Toxicity Estimate
acronyms CLP = Classification, Labelling and Packaging Regulation [Regulation (EC) No.
1272/2008]
DMEL = Derived Minimal Effect Level
DNEL = Derived No Effect Level
EUH statement = CLP-specific Hazard statement
PBT = Persistent, Bioaccumulative and Toxic
PNEC = Predicted No Effect Concentration
RRN = REACH Registration Number
vPvB = Very Persistent and Very Bioaccumulative
N/A = Not available
Key literature references : Regulation (EC) No. 1272/2008 [CLP]
and sources for data ADR = The European Agreement concerning the International Carriage of
Dangerous Goods by Road
IATA = International Air Transport Association
IMDG = International Maritime Dangerous Goods
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by
Commission Regulation (EU) 2015/830
Directive 2012/18/EU, and relative amendments & additions
Directive 2008/98/EC, and relative amendments & additions
Directive 2009/161/EU, and relative amendments & additions
CEPE Guidelines

Procedure used to derive the classification according to Regulation (EC) No. 1272/2008 [CLP/GHS]

Classification Justification
Flam. Liq. 3, H226 On basis of test data
Skin Irrit. 2, H315 Calculation method
Eye Irrit. 2, H319 Calculation method
Skin Sens. 1, H317 Calculation method
STOT RE 1, H372 Calculation method
Aquatic Chronic 3, H412 Calculation method

Full text of abbreviated H : H225 Highly flammable liquid and vapor.

statements H226 Flammable liquid and vapor.
H304 May be fatal if swallowed and enters airways.
H312 Harmful in contact with skin.
H315 Causes skin irritation.
H317 May cause an allergic skin reaction.
H319 Causes serious eye irritation.
H332 Harmful if inhaled.
H335 May cause respiratory irritation.
H372 Causes damage to organs through prolonged or repeated
exposure.
H373 May cause damage to organs through prolonged or repeated
exposure.
H411 Toxic to aquatic life with long lasting effects.
H412 Harmful to aquatic life with long lasting effects.
EUH066 Repeated exposure may cause skin dryness or cracking.
Full text of classifications : Acute Tox. 4 ACUTE TOXICITY - Category 4
[CLP/GHS] Aquatic Chronic 2 AQUATIC HAZARD (LONG-TERM) - Category 2
Aquatic Chronic 3 AQUATIC HAZARD (LONG-TERM) - Category 3
Asp. Tox. 1 ASPIRATION HAZARD - Category 1
Eye Irrit. 2 SERIOUS EYE DAMAGE/ EYE IRRITATION - Category 2
Flam. Liq. 2 FLAMMABLE LIQUIDS - Category 2
Flam. Liq. 3 FLAMMABLE LIQUIDS - Category 3
Skin Irrit. 2 SKIN CORROSION/IRRITATION - Category 2
Skin Sens. 1 SKIN SENSITIZATION - Category 1
STOT RE 1 SPECIFIC TARGET ORGAN TOXICITY (REPEATED

Date of issue/Date of revision : 25, Jun, 2021 Date of previous issue : 13, Apr, 2021 Version : 13.01 15/16
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II
Macropoxy 646 Multi-Purpose Epoxy - Additive
M646A

SECTION 16: Other information

EXPOSURE) - Category 1
STOT RE 2 SPECIFIC TARGET ORGAN TOXICITY (REPEATED
EXPOSURE) - Category 2
STOT SE 3 SPECIFIC TARGET ORGAN TOXICITY (SINGLE
EXPOSURE) - Category 3
Date of printing : 25, Jun, 2021.

Date of issue/ Date of : 25, Jun, 2021

revision
Date of previous issue : 13, Apr, 2021

: If there is no previous validation date please contact your supplier for more
information.
Version : 13.01

Notice to reader
It is recommended that each customer or recipient of this Safety Data Sheet (SDS) study it carefully and
consult resources, as necessary or appropriate, to become aware of and understand the data contained in this
SDS and any hazards associated with the product. This information is provided in good faith and believed to
be accurate as of the effective date herein. However, no warranty, express or implied, is given. The information
presented here applies only to the product as shipped. The addition of any material can change the
composition, hazards and risks of the product. Products shall not be repackaged, modified, or tinted except
as specifically instructed by the manufacturer, including but not limited to the incorporation of products not
specified by the manufacturer, or the use or addition of products in proportions not specified by the
manufacturer. Regulatory requirements are subject to change and may differ between various locations and
jurisdictions. The customer/buyer/user is responsible to ensure that his activities comply with all country,
federal, state, provincial or local laws. The conditions for use of the product are not under the control of the
manufacturer; the customer/buyer/user is responsible to determine the conditions necessary for the safe use
of this product. The customer/buyer/user should not use the product for any purpose other than the purpose
shown in the applicable section of this SDS without first referring to the supplier and obtaining written
handling instructions. Due to the proliferation of sources for information such as manufacturer-specific SDS,
the manufacturer cannot be responsible for SDSs obtained from any other source.

Date of issue/Date of revision : 25, Jun, 2021 Date of previous issue : 13, Apr, 2021 Version : 13.01 16/16