Reported is a unique case of Chiari imalforma tion with syringomyelia and medullar hemorrhage, which became symptomatic 4 days after a craniocervical trauma when the patient was doing neck exercises. The patient manifested respiratory... more
Reported is a unique case of Chiari imalforma tion with syringomyelia and medullar hemorrhage, which became symptomatic 4 days after a craniocervical trauma when the patient was doing neck exercises. The patient manifested respiratory arrest, tetraparesis, and persistent lower cranial nerve dysfunction. Magnetic resonance imaging studies revealed a Chiari i ma!formation with a large cervicothoracic syringomyelia defect and medullar hemorrhage. The patient underwent surgery but some symptoms persisted after the operation. Type i Chiari ma!formation should be included in the differential diagnosis of patients who present with extremity weakness (upper or lower), lower cranial nerve palsy, or respiratory arrest after trauma or neck exercises.
Malignant fibrous histiocytoma rarely affects the cranium. This report describes a case of primary osseous malignant fibrous histiocytoma of the temporal bone in a 58-year-old male patient. The tumor was thought to have originated in the... more
Malignant fibrous histiocytoma rarely affects the cranium. This report describes a case of primary osseous malignant fibrous histiocytoma of the temporal bone in a 58-year-old male patient. The tumor was thought to have originated in the inner table of the bone of the skull, with subsequent intracranial-extracranial extension. Lung metastasis developed and the patient died 6 months after the histopathological diagnosis. We discuss the case and review the relevant literature.
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Research Interests: Pain, Treatment Outcome, Case Report, Humans, Female, and 4 moreAdult, Leg, lumbar vertebrae, and Spinal diseases
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Leiomyosarcomas are malignant tumors of smooth muscle origin. These tumors are very rare in the head and neck region. The majority of leiomyosarcomas of the head and neck arise in the paranasal sinuses, oral cavity, jaws and superficial... more
Leiomyosarcomas are malignant tumors of smooth muscle origin. These tumors are very rare in the head and neck region. The majority of leiomyosarcomas of the head and neck arise in the paranasal sinuses, oral cavity, jaws and superficial soft tissues like the scalp. A mass was observed in the right temporoparietal region of the scalp of a 76-year-old female. Two years before presentation, the patient was operated for primary uterine leiomyosarcoma. Over the ensuing years, the mass substantially increased in size. Radiologic findings revealed a mixed density mass of the right temporalis muscle. Histologic and immunohistochemical examination of the tumor showed a malignant mesenchymal neoplasm consisting of spindle-shaped atypical mesenchymal cells with marked pleomorphism and central cigar shaped nuclei arranged in fascicles. We report a rare case of uterine leiomyosarcoma metastatic to the temporalis muscle, proven by histopathology.
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The purpose of this study was to study the acute phase effects of adenosine triphosphate (ATP)-MgCl2 on experimental spinal cord clip compression injury. Spinal cord clip compression injury was performed on 36 albino Wistar rats. The rats... more
The purpose of this study was to study the acute phase effects of adenosine triphosphate (ATP)-MgCl2 on experimental spinal cord clip compression injury. Spinal cord clip compression injury was performed on 36 albino Wistar rats. The rats were divided into five groups. T4-T8 total laminectomy was performed on all rats. Group 1: sham-operated group. Group 2: clip compression group. In group 3, ATP-MgCl2 (100 micro mol/kg) was given 2 min before the "clip compression injury." In group 4, ATP-MgCl2 (100 micro mol/kg) was given 5 min after the clip compression injury. In group 5, ATP MgCl2 (100 micro mol/kg) was administered 8 h after the injury. The spinal cords were excised for a length of 2 cm and deep frozen at -76 degrees C. Tissue malondialdehyde (MDA) levels were used to determine the effects of ATP-MgCl2 on spinal cord lipid peroxidation. In the groups in which ATP MgCl2 was administered after the clip compression injury (groups 4 and 5), the decrease in spinal cord MDA levels was statistically significant when compared with those of the injury group (group 2). Although MDA levels of group 4 were lower than those of group 5, this difference was not statistically significant. Administration of the ATP-MgCl2 before the clip compression injury (in group 3) did not have a statistically significant effect on lipid peroxidation when compared with the injury group (group 2). In this study, we found that ATP-MgCl2 has decreased lipid peroxidation in spinal cord injury and protected the spinal cord from secondary injury after the trauma. We concluded that ATP-MgCl2 may be used in the treatment of spinal cord injuries in conjunction with the other treatment modalities, but further investigations are mandatory.
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We report a case of a 2-month-old boy with chronic encapsulated intracerebral hematoma (EICH) and discuss clinical, radiological and pathological features of the case. Chronic EICH in infants is extremely rare in the literature. Only two... more
We report a case of a 2-month-old boy with chronic encapsulated intracerebral hematoma (EICH) and discuss clinical, radiological and pathological features of the case. Chronic EICH in infants is extremely rare in the literature. Only two cases have been previously reported. One of the cases reported in the literature was supratentorial and the other was infratentorial.
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Peritonitis is a rare complication of ventriculoperitoneal shunt. Shunt infection may be the cause in patients with ventriculoperitoneal shunt, who have acute abdomen. Specific clues taken from patient's history, physical examination... more
Peritonitis is a rare complication of ventriculoperitoneal shunt. Shunt infection may be the cause in patients with ventriculoperitoneal shunt, who have acute abdomen. Specific clues taken from patient's history, physical examination and some further investigations may clarify the diagnosis. This case is a 25-years-old male with a ventriculoperitoneal shunt who presented symptoms of acute abdomen. The patient was admitted with complaints of abdominal pain. There were no neurologic signs or symptoms. Physical examination on admission revealed a mass in the right lower abdomen and abdominal muscular guarding with rebound tenderness. Laboratory studies showed leukocytosis of the peripheral blood. Abdominal ultrasound demonstrated a mass and the preoperative diagnosis was appendicitis. On abdominal exploration, appendix was found to be normal but a catheter infection related omental necrosis was present. Surgical therapy was carried out by withdrawal of the catheter and segmental re...
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Arachnoid cyst rupture causing subdural hygroma is rare. Twenty-one cases have been previously reported in the literature. We report a case of a 9-year-old boy presenting signs and symptoms of increased intracranial pressure due to the... more
Arachnoid cyst rupture causing subdural hygroma is rare. Twenty-one cases have been previously reported in the literature. We report a case of a 9-year-old boy presenting signs and symptoms of increased intracranial pressure due to the rupture of a type III arachnoid cyst causing subdural hygroma. The clinical and radiological findings as well as the management of the patient are discussed in relation to the pertinent literature.
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Research Interests: Computed Tomography, Magnetic Resonance Imaging, Treatment Outcome, Metabolic Bone Disease, Case Report, and 15 moreHumans, Female, Headache, Central Nervous System, Differential Diagnosis, Malignant Fibrous Histiocytoma, Hearing Loss, Parietal Bone, Clinical Sciences, Adult, Temporal Bone, Neurosciences, Magnetic resonance image, Craniotomy, and Dura mater
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Case report. To present a case of central diabetes insipidus (CDI) that developed after a gunshot injury to the thorax and thoracic spinal cord and to discuss the disease process in light of the relevant literature. Antidiuretic hormone... more
Case report. To present a case of central diabetes insipidus (CDI) that developed after a gunshot injury to the thorax and thoracic spinal cord and to discuss the disease process in light of the relevant literature. Antidiuretic hormone (ADH) abnormalities may develop after spinal trauma and/or surgery. Although there are published reports of inappropriate ADH syndrome arising in this clinical picture, CDI is rare. A 33-year-old woman with hemopneumothorax and a gunshot wound to her thoracic spine was treated with chest tube drainage. No surgery was performed for the spinal injury. The patient was paraplegic on admission and rapidly developed excessive urine output. Testing revealed that her serum ADH level was low, consistent with CDI. Desmopressin acetate nasal spray was the prescribed treatment. The patient responded well to the desmopressin acetate spray. CDI is a complicated hormonal disorder characterized by excessive urine output. It is typically linked to an abnormality in the hypothalamohypophyseal axis that markedly reduces ADH production. The most common inciting causes are craniocerebral trauma, brain tumor and/or surgery, and central nervous system infection. Although uncommon, CDI should be considered when a spinal trauma patient develops excessive urine output.
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Osteoma is the most common benign tumor of facial bony structure. Intraorbital extension is extremely rare. We report a case of intraorbital, pedicled osteoma originating from the left orbital roof. The... more
Osteoma is the most common benign tumor of facial bony structure. Intraorbital extension is extremely rare. We report a case of intraorbital, pedicled osteoma originating from the left orbital roof. The patient's ophtalmological examination revealed; only light perception due to the severe amblyopia and posterior capsular opacification in the right eye, and complete visual acuity in the left. His left eye was proptotic and directed to downward lateral gaze position. Using upper blepharoplasty incision, the osteoma was completely excised. There were not any postoperative complications and all ocular symptoms in the left eye were resolved after 1 month.
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The purpose of this study was to study the acute phase effects of adenosine triphosphate (ATP)-MgCl2 on experimental spinal cord clip compression injury. Spinal cord clip compression injury was performed on 36 albino Wistar rats. The rats... more
The purpose of this study was to study the acute phase effects of adenosine triphosphate (ATP)-MgCl2 on experimental spinal cord clip compression injury. Spinal cord clip compression injury was performed on 36 albino Wistar rats. The rats were divided into five groups. T4-T8 total laminectomy was performed on all rats. Group 1: sham-operated group. Group 2: clip compression group. In group 3, ATP-MgCl2 (100 micro mol/kg) was given 2 min before the "clip compression injury." In group 4, ATP-MgCl2 (100 micro mol/kg) was given 5 min after the clip compression injury. In group 5, ATP MgCl2 (100 micro mol/kg) was administered 8 h after the injury. The spinal cords were excised for a length of 2 cm and deep frozen at -76 degrees C. Tissue malondialdehyde (MDA) levels were used to determine the effects of ATP-MgCl2 on spinal cord lipid peroxidation. In the groups in which ATP MgCl2 was administered after the clip compression injury (groups 4 and 5), the decrease in spinal cord MDA levels was statistically significant when compared with those of the injury group (group 2). Although MDA levels of group 4 were lower than those of group 5, this difference was not statistically significant. Administration of the ATP-MgCl2 before the clip compression injury (in group 3) did not have a statistically significant effect on lipid peroxidation when compared with the injury group (group 2). In this study, we found that ATP-MgCl2 has decreased lipid peroxidation in spinal cord injury and protected the spinal cord from secondary injury after the trauma. We concluded that ATP-MgCl2 may be used in the treatment of spinal cord injuries in conjunction with the other treatment modalities, but further investigations are mandatory.
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Primary cranial Ewing's sarcoma is a very rare malignant tumor. Primary temporal bone Ewing's sarcoma with intraorbital extension is also a very rare condition. In this article we describe a case of primary Ewing's... more
Primary cranial Ewing's sarcoma is a very rare malignant tumor. Primary temporal bone Ewing's sarcoma with intraorbital extension is also a very rare condition. In this article we describe a case of primary Ewing's sarcoma of the temporal bone which extended into intracranial, extracranial and intraorbital compartments; manifesting with a swelling in the zygomatic fossa and proptosis of the right eye. The tumor was excised partially, and the patient underwent radiochemotherapy. The patient died 6 months after the therapy, with lung metastasis. The case is discussed with the pertinent literature.
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OBJECTIVE AND IMPORTANCE We describe the presentation, screening, management, and clinical outcome of a 21-year-old man who sought care for a ruptured middle cerebral artery (MCA) aneurysm and midaortic syndrome (MAS). Only three cases of... more
OBJECTIVE AND IMPORTANCE We describe the presentation, screening, management, and clinical outcome of a 21-year-old man who sought care for a ruptured middle cerebral artery (MCA) aneurysm and midaortic syndrome (MAS). Only three cases of MAS and intracranial aneurysm rupture have previously been described in the literature. CLINICAL PRESENTATION Cranial computed tomographic (CT) scanning, cerebral and abdominal angiography, and multislice three-dimensional CT angiography were used to evaluate intracerebral hemorrhage and to assess medically intractable hypertension in the patient. Digital subtraction angiography revealed a right MCA aneurysm, and multislice three-dimensional CT angiography revealed narrowing of the abdominal aorta. INTERVENTION The patient's right MCA aneurysm was successfully clipped via a right pterional craniotomy. A narrowed abdominal aorta was confirmed by an abdominal aortic angiogram (performed at Day 5 after surgery) and then dilated by using percutaneo...
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A case of pilocytic astrocytoma of neurohypophysis is presented. The clinical, pathological and MRI features of a rare tumor of the neurohypophysis are described. A 5-year-old girl presented with a 3 month history of lethargy, imbalance... more
A case of pilocytic astrocytoma of neurohypophysis is presented. The clinical, pathological and MRI features of a rare tumor of the neurohypophysis are described. A 5-year-old girl presented with a 3 month history of lethargy, imbalance and visual disturbances. A MRI revealed a large suprasellar mass. Histopathological examination demonstrated a pilocytic astrocytoma. Its astrocytic nature was confirmed by positive immunostaining for GFAP and the findings of an electron microscopy.
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Haemangiopericytoma (HPC) is a rare tumour of the central nervous system. Previously, HPCs were thought to originate from meninges and ventricular walls. Currently, they are accepted as distinctive mesenchymal neoplasms unrelated to... more
Haemangiopericytoma (HPC) is a rare tumour of the central nervous system. Previously, HPCs were thought to originate from meninges and ventricular walls. Currently, they are accepted as distinctive mesenchymal neoplasms unrelated to meningiomas. Imaging appearances, clinical progression and haemorrhage into a cystic tumour is documented in an 18-year-old man where the final diagnosis, with histopathological verification, proved to be a cystic HPC. This interesting and illustrative case is discussed with the relevant literature.
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Research Interests: English language, Clinical Neuroscience, Magnetic Resonance Imaging, Immunohistochemistry, Literature Review, and 15 moreCase Report, Humans, Female, Male, Mucin, Exploration, Meningioma, Clinical Sciences, Middle Aged, Multiple, English Language, Nuclear Magnetic Resonance Imaging, Neurosciences, Brain Neoplasms, and Magnetic resonance image
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Research Interests: Computed Tomography, Clinical Neuroscience, Magnetic Resonance Imaging, Humans, Female, and 13 moreClinical, Male, Clinical Sciences, Aged, Middle Aged, Longitudinal Studies, Adult, Retrospective Studies, X ray Computed Tomography, Carotid Artery, Neurosciences, Digital Subtraction Angiography Market, and Magnetic resonance image
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In this paper, a patient with mucolipidosis II (I-cell disease) is described. The initial findings were microcephaly and metopic craniosynostosis. He had coarse facial features and dysostosis multiplex. The first child in his family had... more
In this paper, a patient with mucolipidosis II (I-cell disease) is described. The initial findings were microcephaly and metopic craniosynostosis. He had coarse facial features and dysostosis multiplex. The first child in his family had died with severe bone pathology at 5 months of age. The case is presented to emphasize that craniosynostosis may be the first symptom in mucolipidosis II.
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We report a case of a 2-month-old boy with chronic encapsulated intracerebral hematoma (EICH) and discuss clinical, radiological and pathological features of the case. Chronic EICH in infants is extremely rare in the literature. Only two... more
We report a case of a 2-month-old boy with chronic encapsulated intracerebral hematoma (EICH) and discuss clinical, radiological and pathological features of the case. Chronic EICH in infants is extremely rare in the literature. Only two cases have been previously reported. One of the cases reported in the literature was supratentorial and the other was infratentorial.
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In this study, we aimed to calculate device utilization ratios and device-associated infection rates to examine isolated agents and infection control measures in the Neurology-Neurosurgery Intensive Care Unit (NNICU) of Karadeniz... more
In this study, we aimed to calculate device utilization ratios and device-associated infection rates to examine isolated agents and infection control measures in the Neurology-Neurosurgery Intensive Care Unit (NNICU) of Karadeniz Technical University Faculty of Medicine between ...
To present a 42-year-old female patient with multifocal cavernous hemangioma of the skull associated with nasal osteoma. A case report. INTERVENTION METHODS: X-rays, computerized tomography, magnetic resonance imaging, and histopathology... more
To present a 42-year-old female patient with multifocal cavernous hemangioma of the skull associated with nasal osteoma. A case report. INTERVENTION METHODS: X-rays, computerized tomography, magnetic resonance imaging, and histopathology were used to achieve the diagnosis of this rare entity. The multiple cavernous hemangiomas were resected en-bloc and a curettage biopsy was obtained from the nasal osteoma. The patient healed well after the operation. No recurrences of the cavernous hemangiomas were observed after one-year follow-up. Multifocal cavernous hemangiomas are rare benign lesions of the calvarium, arising from the intrinsic vasculature of the bone. Although they are benign, radiological findings are not always characteristic and their multiple presentation may easily make surgeons consider the other malignancies of the skull in the differential diagnosis. Histopathologic confirmation of the tumor is the definitive method for diagnosis. The treatment of choice is early en bloc resection of the tumour where it is possible.