Coronovirus

Background: Coronaviruses are a group of related viruses that cause diseases in mammals and birds. In humans, coronaviruses cause respiratory tract infections that can range from mild to lethal. Mild illnesses include some cases of the common cold, while more lethal varieties can cause SARS, MERS, and COVID-19. The outbreak was identified in Wuhan, China, in December 2019, declared to be a Public Health Emergency of International Concern on 30 January 2020, and recognized as a pandemic on 11 March 2020. Introduction: Coronaviruses are the subfamily Orthocoronavirinae, within the family of Coronaviridae, order Nidovirales, and realm Riboviria. They are enveloped viruses with a positive-sense single-stranded RNA genome and a nucleocapsid of helical symmetry. The genome size of coronaviruses is approximately from 26 to 32 kilobases. Coronaviruses were first discovered in the 1930s and Human coronaviruses were discovered in the 1960s. The earliest ones studied were from human patients with the common cold, which were later named human coronavirus 229E and human coronavirus OC43. Other human coronaviruses have since been identified, including SARS-CoV in 2003, HCoV NL63 in 2004, HKU1 in 2005, MERS-CoV in 2012, and SARS-CoV-2 in 2019. Most of these have involved serious respiratory tract infections. Result and discussion: Based on our multidisciplinary research, we have found the major cause and some treatments methods for fighting this powerful pathogen. The prime cause of COVID-19 is pushing the mitochondrial to lose MMP. A loss of the MMP by any mechanism leads to functional and structural collapse of the mitochondria and cell death. Mitophagy plays an important role in maintaining mitochondrial homeostasis, but can also eliminate healthy mitochondria in cases such as cell starvation, viral invasion, and erythroid cell differentiation. The mitochondrial fusion and fission are highly dynamic. Viruses specially COVID-19, interfere with these processes to distort mitochondrial dynamic to facilitate their proliferation. Thus, interfering with these processes promotes the interference of different cellular signaling pathways. The severe acute respiratory syndrome coronavirus (SARS-CoV) escapes the innate immune response by translocating its ORF-9b to mitochondria and promotes proteosomal degradation of dynamin-like protein (Drp1) leading to mitochondrial fission. We also researched on Ultrasonic Energy to destroy the virus which lead to positive results but it needs more future research. The most destructive way of viruses is to enhance Reactive Oxygen Species (ROS) and free radicals in human contaminated cell which cause inflammation in a host cell. ELF-EMF convert free radicals into less active molecules and eliminate them into two pathways which has been discussed in the discussion part. Using ELF-EMF affects the second pathway that relies on the activity of the catalase and superoxide dismutase enzymes which is the most effective pathway. For the best result of treatment, is the use of low-frequency magnetic fields (LFMF) plus EMF-ELF which penetrate into deeper tissues, cells and mitochondria. We also have gone through many researches since 1920 and found if we emit the frequency as the same frequency of COVID-19, can cause resonance in the virus and destroy it. So we measured the SARS-CoV-2 frequency by Cyclotron and calculated the frequency of the virus is 30 KHz-500 KHz. Conclusion: COVID-19 (SARS-CoV-2) is one of the most complex virus which has been discovered since 2020. Until today, there has been no Antiviral Drug which can be useful in the treatment of this infectious disease has been discovered till today. COVID-19 genomic sequence containing SARS-CoV, MERS-CoV and Influenza A. Therefore; there is a high possibility of continuing COVID-19 even in summer. To gain the best result in treatment, we should use low-frequency magnetic fields (LFMF) plus EMF which penetrate into deeper tissues, cells and mitochondria in order to reduce ROS and Inflammation. In order to destroy SARSCoV-2 virus in environment and also in infected individuals, we should use ELF-EMF plus LFMF. We also have gone through many researches since 1920 and found if we emit the frequency as the same frequency of COVID-19, it can cause resonance in the virus and destroy it. So we measured the SARS-CoV-2 frequency by Cyclotron and calculated the frequency of the virus that id is 30 KHz-500 KHz. The differences in the frequencies is due to the size of the virus which is from 26 to 32 Kilobases.

There are two major challenging problems facing humanity today which are the ongoing Coronavirus disease (COVID-19) pandemic started in late 2019 and the environmental crisis due to fossil fuels combustion causing over increase of greenhouse gases in the atmosphere. While the first problem seems to be a temporary remedy for the second one due to less travels by individuals, actual solution of both problems may require comprehensive scientific, technological, and socioeconomic decisions. In this report we look at the role of nanotechnology and nano-scale materials towards the solution of these two major challenges.

Mediante el presente artículo se busca recordar o poner a conocimiento las diferentes modalidades de trabajo a distancia que existen dentro de nuestro sistema jurídico; así como, su evolución en el tiempo, su ámbito de aplicación; entendiendo sus ventajas y deficiencias; más aún, analizando la relevancia que estos tienen en el estado de emergencia que viene afrontando nuestro país por el coronavirus.

El trabajo presenta un análisis de las perspectivas del regionalismo sudamericano en términos de salud pública, sus rasgos definitorios como diplomacia regional —que afectan a la política nacional y global de la salud—, y los desafíos de cara a la gestión del coronavirus. A continuación, se ofrece un análisis crítico sobre las respuestas de los gobiernos ante la crisis desatada por la pandemia. Finalmente, se reflexiona sobre las oportunidades que la crisis podría generar para reconstruir una gobernanza regional en salud.

Con la pandemia de enfermedad por coronavirus de 2019, nuestras vidas cotidianas se han visto transfiguradas de un modo súbito y radical, y con unas consecuencias últimas que todavía no somos capaces de vislumbrar. Mediante una serie de artículos que publicaremos próximamente, Buddhistdoor en Español desea poner el foco sobre los diversos aspectos de esta crisis—emocionales, psicológicos, económicos, políticos, sociales, culturales y civilizacionales—y articular, desde una perspectiva budista, cómo afrontar y da respuesta a la situación de emergencia que estamos viviendo.

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While research and reporting on COVID-19 disease focused on laboratory-confirmed cases, minimal to no reporting happen to suspected cases. Initially, WHO advised screen and quarantine strategy. All suspected cases who had mild symptoms were advised to have COVID-19 polymerase chair reaction test.Patients with positive results are advised to quarantine in either home or quarantine facilities dependant on local guidance. Feasibility of testing and isolation strategy seems unlikely in many settings because of the strain on resources; guidance was updated in different countries. Centers for disease control (CDC) and many international guidelines advised home isolation with no testing for suspected cases with mild symptoms. Case definition was updated on different occasions, but suspected cases generically defined based on history and/or risk factors.

Digital education is an invasive medium that heightens the dangers of surveillance. File Photo • • The coronavirus pandemic has upended our world and forced upon us a closure that was unprecedented and left most, unprepared. Schools, colleges, universities all over India have been majorly impacted and the academic calendar has been severely disturbed. Educational institutions will probably not open before August 2020 according to the latest announcements made by the HRD ministry and the union minister of Higher Education (HE) particularly in places that are marked out as red zones and have a rising incidence of the virus infection. The pandemic has given legitimacy to an otherwise warped, insidious plan of a takeover of education by the online methodology, seen as the panacea for all present-day evils facing our education system. Online teaching methods have been in use before the pandemic and certain categories of students have been using this platform for self-study, which no doubt can be beneficial and effective in their own context. What is undermined

The novel coronavirus (COVID-19) infections have adopted the shape of a global pandemic now, demanding an urgent vaccine design. The current work reports contriving an anti-coronavirus peptide scanner tool to discern anti-coronavirus targets in the embodiment of peptides. The proffered CoronaPep tool features the fast fingerprinting of the anti-coronavirus target serving supreme prominence in the current bioinformatics research. The anti-coronavirus target protein sequences reported from the current outbreak are scanned against the anti-coronavirus target data-sets via CORONAPEP which provides precision-based anti-coronavirus peptides. This tool is specifically for the coronavirus data, which can predict peptides from the whole genome, or a gene or protein's list. Besides it is relatively fast, accurate, userfriendly and can generate maximum output from the limited information. The availability of tools like CORONAPEP will immeasurably perquisite researchers in the discipline of oncology and structure-based drug design.

As respostas em bioética nunca são simples. Para ilustrar, o Supremo Tribunal Federal examina a constitucionalidade da vacinação compulsória, isto é, impor a todos a vacina. Este artigo, no entanto, não examina tal possibilidade. A reflexão proposta parte de um cenário hipotético em que se admita a recusa. O questionamento central é: caso a imunização não seja imperativa, podem ser estabelecidas restrições a quem recusá-la? O ponto de partida, então, é a vacinação obrigatória, em que a recusa é permitida, contudo, "penaliza-se" quem não se vacinar. A temática, como tantas outras que entrelaçam saúde e Direito, desafia o sentido e o alcance desses termos. O significado de saúde é complexo. Concebe-se como bem-estar físico, mental e social e, igualmente, associa-se, como ensina Canguilhem, à ausência de doenças, à normalidade, ou ao equilíbrio (homeostase).

The world is facing biggest crisis after Warfare II. Almost every country has been suffering from the disastrous coronavirus disease (COVID-19). transmitted through direct contact with respiratory droplets (generated through coughing and sneezing) of an infected person. Individual may infect from touching surfaces contaminated with the virus and touching their face. This virus can present couple of hours in air also. COVID-19 is transmitted through direct contact with respiratory droplets of an infected person. Individual may infect from touching surfaces contaminated with the virus and touching their face. To forestall further transmission it's important that communities take action to further transmission, reduce impact of the Corona virus and support control measures. Government of India taking all necessary steps to face challenge of COVID-19. With the active support of citizens and warriors of India, India are ready to contain the spread of the virus in country. It's important to empower the citizens with the correct information and taking precautions as per advisory being issued by the Ministry of Health and Family Welfare to forestall the spread of community transfer of virus.