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Research Interests: Geology and Fact Sheet
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Societal perspectives on higher education are evolving, and successful institutions will have to evolve with them. While public pressure demands greater emphasis on ethics and career-readiness, business programs stand accused... more
Societal perspectives on higher education are evolving, and successful institutions will have to evolve with them. While public pressure demands greater emphasis on ethics and career-readiness, business programs stand accused overemphasizing quantitative analysis over higher level thinking, self-reflection and self-motivation, often resulting in "directionless" students. This paper reviews private sector self-motivation programs focusing on business related skills, promising greater career success and self-empowerment, and explores their possible adaptation to business programs. Real world examples are provided and implications are discussed.
How does complex social behavior evolve? What are the developmental building blocks of division of labor and specialization, the hallmarks of insect societies? Studies have revealed the developmental origins in the evolution of division... more
How does complex social behavior evolve? What are the developmental building blocks of division of labor and specialization, the hallmarks of insect societies? Studies have revealed the developmental origins in the evolution of division of labor and specialization in foraging worker honeybees, the hallmarks of complex insect societies. Selective breeding for a single social trait, the amount of surplus pollen stored in the nest (pollen hoarding) revealed a phenotypic architecture of correlated traits at multiple levels of biological organization in facultatively sterile female worker honeybees. Verification of this phenotypic architecture in "wild-type" bees provided strong support for a "pollen foraging syndrome" that involves increased senso-motor responses, motor activity, associative learning, reproductive status, and rates of behavioral development, as well as foraging behavior. This set of traits guided further research into reproductive regulatory systems ...
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... Omote, S., I. Karakama, N. Nakajima, S. Saito, and I. Kayano, Aftershocks of the Kita Mino earthquake of August 19, 1961 (in Japanese with English ... Richter, CF, Foreshocks and aftershocks, in Earthquakes in Kern County, Cali]ornia... more
... Omote, S., I. Karakama, N. Nakajima, S. Saito, and I. Kayano, Aftershocks of the Kita Mino earthquake of August 19, 1961 (in Japanese with English ... Richter, CF, Foreshocks and aftershocks, in Earthquakes in Kern County, Cali]ornia during 1952, edited by GB Oakeshott, Calif. ...
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Research Interests: Genetics, Animal Behavior, Biology, Medicine, Comparative Physiology, and 15 moreQTL mapping, Biological Sciences, Bees, Apis mellifera, Pollen, Animals, Taste, Foraging Behavior, Quantitative Trait Loci, Locomotor Activity, Exploratory Behavior, Species Specificity, Honeybee, Motor activity, and Medical and Health Sciences
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ABSTRACT The crustal structure beneath the exposed terranes of southern Alaska has been explored using coincident seismic refraction and reflection profiling. A wide-angle reflector at 8–9 km depth, at the base of an inferred low-velocity... more
ABSTRACT The crustal structure beneath the exposed terranes of southern Alaska has been explored using coincident seismic refraction and reflection profiling. A wide-angle reflector at 8–9 km depth, at the base of an inferred low-velocity zone, underlies the Peninsular and Chugach terranes, appears to truncate their boundary, and may represent a horizontal decollement beneath the terranes. The crust beneath the Chugach terrane is characterized by a series of north-dipping paired layers having low and high velocities that may represent subducted slices of oceanic crust and mantle. This layered series may continue northward under the Peninsular terrane. Earthquake locations in the Wrangell Benioff zone indicate that at least the upper two low-high velocity layer pairs are tectonically inactive and that they appear to have been accreted to the base of the continental crust. The refraction data suggest that the Contact fault between two similar terranes, the Chugach and Prince William terranes, is a deeply penetrating feature that separates lower crust (deeper than 10 km) with paired dipping reflectors, from crust without such reflectors.
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... the continental crust and has been doc-umented in many regions around the globe, mainly with geologic and paleomagnetic evidence (Kissel and Laj ... a tectonic model of crustal blocks rotating within a dextral shear zone formed by the... more
... the continental crust and has been doc-umented in many regions around the globe, mainly with geologic and paleomagnetic evidence (Kissel and Laj ... a tectonic model of crustal blocks rotating within a dextral shear zone formed by the parallel Denali and Tin-tina fault systems ...
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The initiation of foraging during the life course of honeybee workers is of central interest to understanding the division of labor in social insects, a central theme in sociobiology and behavioral research. It also provides one of the... more
The initiation of foraging during the life course of honeybee workers is of central interest to understanding the division of labor in social insects, a central theme in sociobiology and behavioral research. It also provides one of the most complex phenotypic traits in biological systems because of the interaction of various external, social, and individual factors. This study reports on a comprehensive investigation of the genetic architecture of the age of foraging initiation in honeybees. It comprises an estimation of genetic variation, the study of candidate loci, and two complementary quantitative trait loci (QTL) maps using two selected, continually bred lines of honeybees. We conclude that considerable genetic variation exists between the selected lines for this central life history component. The study reveals direct pleiotropic and epistatic effects of candidate loci (including previously identified QTL for foraging behavior). Furthermore, two maps of the honeybee genome we...
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One of the best examples of a natural behavioral syndrome is the pollen-hoarding syndrome in honeybees that ties together multiple behavioral phenotypes, ranging from foraging behavior to behavioral ontogeny and learning performance. A... more
One of the best examples of a natural behavioral syndrome is the pollen-hoarding syndrome in honeybees that ties together multiple behavioral phenotypes, ranging from foraging behavior to behavioral ontogeny and learning performance. A central behavioral factor is the bees' responsiveness to sucrose, measured as their proboscis extension reflex. This study examines the genetics of this trait in diploid worker and haploid male honeybees (drones) to learn more about the genetic architecture of the overall behavioral syndrome, using original strains selected for pollen-hoarding behavior. We show that a significant proportion of the phenotypic variability is determined by genotype in males and workers. Second, our data present overwhelming evidence for pleiotropic effects of previously identified quantitative trait loci for foraging behavior (pln-QTL) and epistatic interactions among them. Furthermore, we report on three genomic QTL scans (two reciprocal worker backcrosses and one d...
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model does not appear to fit. The final two chapters discuss the media’s contribution to public disorder and advocate greater accountability of and understanding by the police to prevent disorder in the future. This brief description... more
model does not appear to fit. The final two chapters discuss the media’s contribution to public disorder and advocate greater accountability of and understanding by the police to prevent disorder in the future. This brief description indicates the breadth of the flashpoints model. The problem with it is in its lack of specificity. As the book’s sub-title indicates, Waddington seeks to analyse disorder both comparatively (mainly this
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We investigated the crustal structure and tectonic evolution of the North American continent in Alaska, where the continent has grown through magmatism, accretion, and tectonic underplating. In the 1980's and... more
We investigated the crustal structure and tectonic evolution of the North American continent in Alaska, where the continent has grown through magmatism, accretion, and tectonic underplating. In the 1980's and early 1990's, we conducted a geological and geophysical investigation, known as the Trans-Alaska Crustal Transect (TACT), along a 1350-km-long corridor from the Aleutian Trench to the Arctic coast. The most
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Strong-motion data from earthquakes of western North America are examined to provide the basis for estimating peak acceleration, velocity, and displacement as a function of distance for three magnitude classes, 5.0 to 5.7, 6.0 to 6.4, and... more
Strong-motion data from earthquakes of western North America are examined to provide the basis for estimating peak acceleration, velocity, and displacement as a function of distance for three magnitude classes, 5.0 to 5.7, 6.0 to 6.4, and 7.1 to 7.6. Analysis of a subset of the data from the San Fernando earthquake shows that small but statistically significant differences exist between peak values of horizontal acceleration, velocity, and displacement recorded on soil at the base of small structures and values recorded at the base of large structures. The peak acceleration tends to be less and the peak velocity and displacement to be greater at the base of large structures than at the base of small structures. In the distance range used in the regression analysis (15 to 100 km), the values of peak horizontal acceleration recorded at soil sites in the San Fernando earthquake are not significantly different from the values recorded at rock sites, but values of peak horizontal velocit...
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... questions about the earthquake resistance of structures. Robert A. Page, John A. Blume, William B. Joyner On 9 February 1971, a magnitude 6.6 critical locations than the SanFernando earthquake occurred in San Fernando, earthquake. ...
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employed with equal comfort by people from different parts of the political spectrum. The authors lay great stress on the belief that a radical empowerment strategy must ’actively confront oppression’ (p24). Accordingly, practitioners who... more
employed with equal comfort by people from different parts of the political spectrum. The authors lay great stress on the belief that a radical empowerment strategy must ’actively confront oppression’ (p24). Accordingly, practitioners who subscribe to the tenets of empowerment must aim to facilitate ’real change amongst groups of service users’ (p24) whilst simultaneously ’confronting their own oppressive attitudes’ (p25) in order to avoid the charge of professional opportunism. Ward and Mullender offer some guidance to practitioners who might wish
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The election of David Cameron as the new Conservative leader in 2005 signalled the emergence of the ‘progressive’ neo-liberal Conservative approach to the welfare state (Clark and Hunt, 2007; Osborne, 2009; Cameron, 2010). Labour’s... more
The election of David Cameron as the new Conservative leader in 2005 signalled the emergence of the ‘progressive’ neo-liberal Conservative approach to the welfare state (Clark and Hunt, 2007; Osborne, 2009; Cameron, 2010). Labour’s success in rebranding itself as New Labour convinced Cameron and his associates that the Conservatives could gain electoral traction from a similar make over. This repositioning was not deemed to require any modifications to the party’s neo-liberal approach to economic policy not least because of New Labour’s conversion to the merits of this doctrine. In contrast, the construction of a progressive social narrative was deemed necessary to ‘detoxify’ the Conservative ‘brand’ and to highlight how the party’s agenda in this sphere differed from the overly statist strategy of New Labour. Cameron wanted to develop a bolder, more enterprising doctrine that involved the recalibration, rather than the rejection, of neo-liberal conservatism. Although Conservatives ...
Submitted for the APR07 Meeting of The American Physical Society Decay spectroscopy of the lightest proton-emitting Re isotopes IAIN DARBY, University of Liverpool, DAVID JOSS, ROBERT PAGE, JUHA UUSITALO, JOHN SIMPSON, GREAT COLLABORATION... more
Submitted for the APR07 Meeting of The American Physical Society Decay spectroscopy of the lightest proton-emitting Re isotopes IAIN DARBY, University of Liverpool, DAVID JOSS, ROBERT PAGE, JUHA UUSITALO, JOHN SIMPSON, GREAT COLLABORATION — Proton emission is expected to determine the limit of experimental observation for the neutrondeficient nuclei of most elements. Proton radioactivity may be treated as a simple quantum tunnelling process through the Coulomb barrier. The barrier penetration probability (and thus the decay halflives) for proton emitters are sensitive to the proton decay energies and the orbital angular momentum of the initial state from which emission occurs. Therefore proton radioactivity is an ideal mechanism with which to determine and characterise single-particle states beyond the proton drip line. Additionally the characteristics (short halflives and discrete energies) of the emitted protons are ideal for tagging in γ-ray spectroscopy experiments. A decay spec...
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© 2016 authors. Published by the American Physical Society.The levels in Sn129 populated from the β- decay of In129 isomers were investigated at the ISOLDE facility of CERN using the newly commissioned ISOLDE Decay Station (IDS). The... more
© 2016 authors. Published by the American Physical Society.The levels in Sn129 populated from the β- decay of In129 isomers were investigated at the ISOLDE facility of CERN using the newly commissioned ISOLDE Decay Station (IDS). The lowest 12+ state and the 32+ ground state in Sn129 are expected to have configurations dominated by the neutron s12 (l=0) and d32 (l=2) single-particle states, respectively. Consequently, these states should be connected by a somewhat slow l-forbidden M1 transition. Using fast-timing spectroscopy we have measured the half-life of the 12+ 315.3-keV state, T12= 19(10) ps, which corresponds to a moderately fast M1 transition. Shell-model calculations using the CD-Bonn effective interaction, with standard effective charges and g factors, predict a 4-ns half-life for this level. We can reconcile the shell-model calculations to the measured T12 value by the renormalization of the M1 effective operator for neutron holes.
Sex determination in Hymenoptera is controlled by haplo-diploidy in which unfertilized eggs develop into fertile haploid males. A single sex determination locus with several complementary alleles was proposed for Hymenoptera [so-called... more
Sex determination in Hymenoptera is controlled by haplo-diploidy in which unfertilized eggs develop into fertile haploid males. A single sex determination locus with several complementary alleles was proposed for Hymenoptera [so-called complementary sex determination (CSD)]. Heterozygotes at the sex determination locus are normal, fertile females, whereas diploid zygotes that are homozygous develop into sterile males. This results in a strong heterozygote advantage, and the sex locus exhibits extreme polymorphism maintained by overdominant selection. We characterized the sex-determining region by genetic linkage and physical mapping analyses. Detailed linkage and physical mapping studies showed that the recombination rate is <44 kb/cM in the sex-determining region. Comparing genetic map distance along the linkage group III in three crosses revealed a large marker gap in the sex-determining region, suggesting that the recombination rate is high. We suggest that a “hotspot” for rec...
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There is a worldwide need for reagents to perform SARS-CoV-2 detection. Some laboratories have implemented kit-free protocols, but many others do not have the capacity to develop these and/or perform manual processing. We provide multiple... more
There is a worldwide need for reagents to perform SARS-CoV-2 detection. Some laboratories have implemented kit-free protocols, but many others do not have the capacity to develop these and/or perform manual processing. We provide multiple workflows for SARS-CoV-2 nucleic acid detection in clinical samples by comparing several commercially available RNA extraction methods: QIAamp Viral RNA Mini Kit (QIAgen), RNAdvance Blood/Viral (Beckman) and Mag-Bind Viral DNA/RNA 96 Kit (Omega Bio-tek). We also compared One-step RT-qPCR reagents: TaqMan Fast Virus 1-Step Master Mix (FastVirus, ThermoFisher Scientific), qPCRBIO Probe 1-Step Go Lo-ROX (PCR Biosystems) and Luna® Universal Probe One-Step RT-qPCR Kit (Luna, NEB). We used primer-probes that detect viral N (EUA CDC) and RdRP (PHE guidelines). All RNA extraction methods provided similar results. FastVirus and Luna proved most sensitive. N detection was more reliable than that of RdRP, particularly in samples with low viral titres. Importa...
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The red-backed salamander (Plethodon cinereus) has long-served as a model system in ecology, evolution, and behavior, and studies surveying molecular variation in this species have become increasingly common over the past decade. However,... more
The red-backed salamander (Plethodon cinereus) has long-served as a model system in ecology, evolution, and behavior, and studies surveying molecular variation in this species have become increasingly common over the past decade. However, difficulties are commonly encountered when extending microsatellite markers to populations that are unstudied from a genetic perspective due to high levels of genetic differentiation across this species' range. To ameliorate this issue, we used 454 pyrosequencing to identify hundreds of microsatellite loci. We then screened 40 of our top candidate loci in populations in Virginia, Pennsylvania, and Ohio-including an isolated island population ~ 4.5 km off the shore of Lake Erie (South Bass Island). We identified 25 loci that are polymorphic in a well-studied region of Virginia and 11 of these loci were polymorphic in populations located in the genetically unstudied regions of Ohio and Pennsylvania. Use of these loci to examine patterns of variat...
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Most organisms are constantly faced with environmental changes and stressors. In diverse organisms, there is an anticipatory mechanism during development that can program adult phenotypes. The adult phenotype would be adapted to the... more
Most organisms are constantly faced with environmental changes and stressors. In diverse organisms, there is an anticipatory mechanism during development that can program adult phenotypes. The adult phenotype would be adapted to the predicted environment that occurred during organism maturation. However, whether this anticipatory mechanism is present in eusocial species is questionable because eusocial organisms are largely shielded from exogenous conditions by their stable nest environment. In this study, we tested whether food deprivation during development of the honey bee (Apis mellifera), a eusocial insect model, can shift adult phenotypes to better cope with nutritional stress. After subjecting fifth instar worker larvae to short-term starvation, we measured nutrition-related morphology, starvation resistance, physiology, endocrinology and behavior in the adults. We found that the larval starvation caused adult honey bees to become more resilient toward starvation. Moreover, t...
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... a higher pyrite content in this zone than the potassic zone but most of the iron is in magne-tite keeping py/cpy ratio around 1. Both early alteration types, potassic and IA, extend upwards to 4200 m where they overlap and host the... more
... a higher pyrite content in this zone than the potassic zone but most of the iron is in magne-tite keeping py/cpy ratio around 1. Both early alteration types, potassic and IA, extend upwards to 4200 m where they overlap and host the highest protore grades in the La Fortuna deposit ...
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Decay properties of the new neutron-deficient nuclide 192At have been studied in the complete fusion reaction 144Sm(51V,3n)192At at the velocity filter SHIP. Two isomeric states with half-lives of 88(6) ms and 11.5(6) ms, respectively,... more
Decay properties of the new neutron-deficient nuclide 192At have been studied in the complete fusion reaction 144Sm(51V,3n)192At at the velocity filter SHIP. Two isomeric states with half-lives of 88(6) ms and 11.5(6) ms, respectively, and with complex alpha-decay schemes were identified in 192At. The decay pattern of one of the isomers suggests that it is based on the oblate-deformed pi2f7/2⊗nu1i13/2
Increasing evidence suggests that neurohumoral manifestations of heart failure may lead to insulin resistance, predisposing patients with heart failure to the development of glucose intolerance or worsening of existing diabetes.... more
Increasing evidence suggests that neurohumoral manifestations of heart failure may lead to insulin resistance, predisposing patients with heart failure to the development of glucose intolerance or worsening of existing diabetes. Theoretically, insulin-sensitizing thiazolidinediones (TZDs) should be beneficial in this patient population. A 74-year-old man with well-compensated systolic dysfunction and longstanding type 2 diabetes mellitus treated with glyburide began therapy with rosiglitazone 4 mg/day, which was increased to 8 mg/day after 1 month. Two weeks later he was seen with a 5-kg weight gain, shortness of breath, bibasilar rales, +S3 gallop, and increased jugular venous distention. Twelve days later symptoms worsened, with pulmonary edema on chest radiograph, continued weight gain, and +4 pitting edema resistant to oral diuretics. The patient was admitted to the hospital for exacerbation of heart failure. Five days after discharge he was readmitted for similar symptoms, including an 11.8-kg weight gain. He reported adherence to drug therapy and diet. Rosiglitazone was immediately discontinued and 11 days later the man&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;s weight stabilized to 79 kg and remained between 79 and 80 kg 2 and 3 months after discharge. This case demonstrates that TZDs may precipitate weight gain and pulmonary and peripheral edema in patients with stable heart failure. Earlier reports documented similar symptoms in patients without a history of heart failure. Although current recommendations state that TZDs should not be administered to patients with New York Heart Association class III or IV disease, practitioners should be aware that these adverse effects also may occur in patients with milder forms heart failure as well as those without heart failure.