Rehab A Rayan
Alexandria University, High Institute of Public Health, Department Member
- Information Technology Institute, Health Informatics, Undergraduateadd
- Health Informatics, Pharmacology, Bioinformatics, TIC, Elearning, Web 2.0, Online Learning, Public Health, and 33 moreClinical Pharmacy, Clinical Pharmacology, Hospital Pharmacy, Virtual Learning, Instructional Technology, Instructional Design, Educational Technology, Distance Education, Distance Learning, Biotechnology, Immunology, Molecular Biology, Genetic Engineering, Digital Media, New Media, Online Journalism, Digital Story Telling, Paywalls, Iphones, Facebook, Google, Digital Marketing, Virtual Revolution, Youtube, Instructional Engineering, Computer-Mediated Communication, Innovation & Change Management, Knowledge Communities, Developmental Work Research, ICT4D, Open Distance Learning, Technology Enhanced Education, and E-learningedit
- Rehab Rayan is a PhD researcher at the Department of Epidemiology, High Institute of Public Health. Rehab researches in Pharmacy, Epidemiology and Clinical Trials.edit
A crucial element of cancer controlling programs for the expanding burden in Egypt is public awareness of preventable risk factors. The study explores the knowledge of some preventable risk factors and beliefs about cancer among adults... more
A crucial element of cancer controlling programs for the expanding burden in Egypt is public awareness of preventable risk factors. The study explores the knowledge of some preventable risk factors and beliefs about cancer among adults attending a primary health care center in an urban area of Alexandria. The researcher conducted a single point, a descriptive cross-sectional study of 85 adults aged ≥18 years in February 2019 using a semi-structured questionnaire to gather data through the face-to-face interviewing method. The data were analyzed by descriptive statistics. Good levels of both cancer knowledge and beliefs were assigned as ≥75% of the total score. Respondent's mean age was 43.6 years and around 64.7% were females. Nearly 74.1% of respondents had a poor knowledge score of cancer preventable risk factors, especially low vegetables and fruit consumption (55.3%) excessive exposure to sun radiations (52.9%), physical inactivity (44.7%), overweight and obesity (44.7%) and pollution (43.5%) respectively. Furthermore, almost 38.8% of respondents had some false beliefs about cancer. Almost 44.7% of respondents disagreed with the presence of signs and symptoms to cancer while around 24.7% of them reported that cancer could not be prevented. Moreover, nearly 25.9% of them disapproved that cancer patients need psychological support. The Study population had poor knowledge of lifestyle-related cancer preventable risk factors and some false beliefs need correction. Therefore, we need to improve public knowledge of these factors that may lead to adopting health-protective behaviors reducing cancer risk.
Research Interests:
Climate Change affects almost all life forms on earth during the evolutionary age of Anthropocene, the current age in which we live. Microorganisms form the basis of ancestral life forms and are crucial in our studies related to the cause... more
Climate Change affects almost all life forms on earth during the evolutionary age of Anthropocene, the current age in which we live. Microorganisms form the basis of ancestral life forms and are crucial in our studies related to the cause and impacts of climate change on a global scale. ‘Microorganisms’ are ascribed as any microscopic organism or virus not visible to the naked eye (smaller than 50 μm) that can exist in a unicellular, multicellular (for example, differentiating species), aggregate (for example, biofilm) or viral form. In addition to microscopic bacteria, archaea, eukaryotes, and viruses, we discuss certain macroscopic unicellular eukaryotes (for example, larger marine phytoplankton) and wood decomposing fungi.
Research Interests:
Progress in computational sciences for cleaning, sorting, combining, digging, visualizing and managing data along with technological advancements in medical devices have urged needs for further extensive and consistent approaches to... more
Progress in computational sciences for cleaning, sorting, combining, digging, visualizing and managing data along with technological advancements in medical devices have urged needs for further extensive and consistent approaches to discuss the common key issues in medicine and health. Artificial Intelligence (AI) has significantly obtained grounds in everyday living in the era of information technology and it has now landed in healthcare. AI studies' in healthcare are evolving swiftly. However, it could only be the start of observing how it will influence patient care. AI tries to simulate human cognitive capacities. It is carrying a transformation pattern to healthcare, strengthened by the escalating availability of clinical data and sped up advancement in analytics systems. Nonetheless, there is a similar doubt, including some pressing warning at these elevated anticipations. This review examines the present state of AI applications in health, major developments in health AI, and the disparate consequences of health AI and offers some directions for institutions and caregivers utilizing AI techniques.
Research Interests:
For improving accomplished attempts to stop smoking, it is necessary to learn about the qualities of individuals who can willingly stop smoking. This study seeks to discover the willingness degree and associated determinants to stop... more
For improving accomplished attempts to stop smoking, it is necessary to learn about the qualities of individuals who can willingly stop smoking. This study seeks to discover the willingness degree and associated determinants to stop smoking between adult visitors of a primary healthcare centre in an urban area of Alexandria in Egypt. In this single point and descriptive cross-sectional study, a semi-structured questionnaire was distributed to a sample of 53 adults aged ≥18 years in May 2019. Descriptive statistical analyses were conducted to evaluate the determinants influencing the willingness to stop smoking. Of the 53 respondents (with a mean age of 38.7 years old), 41.5% of them were males. Almost 18.9% of the respondents were ongoing smokers (36.4% of males and 6.5% of females), though 83.7% of those smokers were willing to stop smoking. The number of male smokers was significantly greater than female smokers (Pearson Chi-Square = 7.52, p-value = 0.006). Determinants, which can favourably influence the willingness to stop smoking, were believing that smoking is a health risk to them (100%) and the others around (94.3%). A bulk of participants (56.6%) doubted the need for nicotine supplements to help in smoking cessation. Smoker respondents were willing to stop smoking. Understanding that smoking is a health hazard for both smokers and the others around can motivate smoking cessation. Relying on nicotine supplements alone might not add favourably to a strong smoking cessation decision. Tailoring campaigns to raise awareness about smoking health hazards’ would support and sustain smoking cessation.
Research Interests: Health Sciences, Behavioral Sciences, Preventive Health, Community Health, Egypt, and 11 morePreventive medicine, Health, Public Health, Attitudes (Social Psychology), Medicine, Smoking Cessation, Smoking, Attitude, Community Health and Preventive Medicine, Medicine and Health Sciences, and Willingness to stop smoking
Background/aim: In Egypt, irrational medication use is a community concern. This study examines patients’ attitudes regarding medication use to promote rational medication use. Materials and methods: In April 2019, A cross-sectional... more
Background/aim:
In Egypt, irrational medication use is a community concern. This study examines patients’ attitudes regarding medication use to promote rational medication use.
Materials and methods:
In April 2019, A cross-sectional study involved a total of 72 patients attending a primary health care centre in Alexandria who responded to a face-to-face questionnaire.
Results:
The respondents’ mean age was 44.94 years and 56.94% of them were females. 77.78% of the respondents stated that when they get sick, they seek medications from the pharmacy without consulting a physician. Moreover, 52.78% of the respondents reported that their relatives recommend medications for them while 48.61% of them recommended medications themselves for their sick relatives. Additionally, 66.67% of the respondents stated that they stopped their medications prior to their physicians’ recommended time and 61.11% of them admitted keeping unused medications at home. 73.61% of the respondents reported reading medication’s prospectus and 75% of them checked the medications’ expiry date before using them. The attitudes of patients’ regarding medication use demonstrated non-significant differences with respect to gender.
Conclusion:
According to this study, patients’ attitudes concerning medication use were found far from rational. Most study respondents practised self-prescription where they acquired medicines based on previous experience, recommending them to others or getting advice from non-professionals. Furthermore, most of the participants stopped taking their medicines when they felt better while keeping them for future use. Eventually, convinced attitudes can add to health hazards, needless consumption or spending. Therefore, Community awareness of rational medication use can minimize the found irrational use.
In Egypt, irrational medication use is a community concern. This study examines patients’ attitudes regarding medication use to promote rational medication use.
Materials and methods:
In April 2019, A cross-sectional study involved a total of 72 patients attending a primary health care centre in Alexandria who responded to a face-to-face questionnaire.
Results:
The respondents’ mean age was 44.94 years and 56.94% of them were females. 77.78% of the respondents stated that when they get sick, they seek medications from the pharmacy without consulting a physician. Moreover, 52.78% of the respondents reported that their relatives recommend medications for them while 48.61% of them recommended medications themselves for their sick relatives. Additionally, 66.67% of the respondents stated that they stopped their medications prior to their physicians’ recommended time and 61.11% of them admitted keeping unused medications at home. 73.61% of the respondents reported reading medication’s prospectus and 75% of them checked the medications’ expiry date before using them. The attitudes of patients’ regarding medication use demonstrated non-significant differences with respect to gender.
Conclusion:
According to this study, patients’ attitudes concerning medication use were found far from rational. Most study respondents practised self-prescription where they acquired medicines based on previous experience, recommending them to others or getting advice from non-professionals. Furthermore, most of the participants stopped taking their medicines when they felt better while keeping them for future use. Eventually, convinced attitudes can add to health hazards, needless consumption or spending. Therefore, Community awareness of rational medication use can minimize the found irrational use.
Research Interests: Pharmacy, Health Promotion, Primary Health Care, Public Health Policy, Health, and 15 morePublic Health, Health Policy, Attitudes (Social Psychology), Health Care Management, Attitude change, Medication Management, Clinical Pharmacy, Patient education, Health and Social Care, Attitudes, Attitude, Beliefs and attitudes, Clinical Pharmacy Practice, Medication, and Medical Electronics
Antibiotic misuse and bacterial resistance is a significant public health concern worldwide. Egypt lacks policies and regulations concerning medication prescriptions. The study explores the knowledge and attitudes regarding antibiotic use... more
Antibiotic misuse and bacterial resistance is a significant public health concern worldwide. Egypt lacks policies and regulations concerning medication prescriptions. The study explores the knowledge and attitudes regarding antibiotic use and resistance among adults attending a primary healthcare centre in an urban area of Alexandria. The researcher conducted a single point, descriptive cross-sectional study on 87 adults aged ≥18 years attending a primary healthcare center in an urban area of Alexandria in January 2019 using a semi-structured questionnaire to gather data about the knowledge and attitudes of using antibiotics and resistance through the face-to-face interviewing method. The data were analyzed by descriptive statistics to explore the respondents’ level of knowledge with respect to the use of antibiotics and resistance. High level of knowledge was assigned as > 66.7% of the total score. About 52.8% of the respondents (63.2% of them were females) lack adequate knowledge about the use and resistance of antibiotics. Almost 65.6% of males had less restrictive knowledge about the use of antibiotics and resistance than 45.5% of the females. Simultaneously, 47.1% of the respondents erroneously believed that antibiotics work on both bacterial and viral infections and 14.9% thought it just fights viruses. Approximately, 66.7% of them were unaware of the meaning of antibiotic resistance. Moreover, 33.3% stated they have no role to play against bacterial resistance. 83.9% of respondents knew that vaccination can prevent bacterial resistance. The findings display poor knowledge and attitudes of proper antibiotic use and resistance among respondents. Healthcare providers should utilize these findings to educate the public on how to rationally use antibiotics and the health hazards of bacterial resistance.
Research Interests:
Background: Patient education includes multiple interventions teaching patients about their health to improve their outcomes. The term has evolved to the more active terms (patient engagement and empowerment). Patients, who are diagnosed... more
Background: Patient education includes multiple interventions teaching patients about their health to
improve their outcomes. The term has evolved to the more active terms (patient engagement and
empowerment). Patients, who are diagnosed with chronic diseases that cost patients a lifelong treatment
and dangerous complications (e.g. Diabetes Mellitus) need to be responsible for their health by self-
management. With more computers and mobile devices owners globally, telehealth offers promising
healthcare technology interventions to improve patient’s health literacy.
Methods: This study involves a structured questionnaire administered online to examine the level of
acceptance to use mobile technology (a form of telehealth approaches) to deliver health-related education.
We collected data through a survey targeting a sample of 56 Egyptian patients aged between 25 and 65
years old in 2014.
Results: The results showed a promising acceptance rate (54%) among respondents; mostly those aged
between 25-35 years agreed to use mobile technology like Short Message Service (SMS) to deliver health-
related educational information to improve their self-managing experience and health outcomes.
Conclusion: We conclude that accompanying the rise in mobile phones subscription and willingness to
receive health-related SMS, mobile health presents an opportunity for health education programs,
especially when targeting younger adults.
Implications: These findings emphasize the potential to introduce more individualized, innovative and
engaging approaches to educate and leverage patients with their own health using technology in a
developing country. We recommend further studies to evaluate the effect of mobile-based patient
education on a sample of chronically diseased patients (e.g. diabetics patients) to measure the desired
outcomes such as lifestyle and self-care behaviours (medication adherence, improved knowledge,
satisfaction and quality of life).
improve their outcomes. The term has evolved to the more active terms (patient engagement and
empowerment). Patients, who are diagnosed with chronic diseases that cost patients a lifelong treatment
and dangerous complications (e.g. Diabetes Mellitus) need to be responsible for their health by self-
management. With more computers and mobile devices owners globally, telehealth offers promising
healthcare technology interventions to improve patient’s health literacy.
Methods: This study involves a structured questionnaire administered online to examine the level of
acceptance to use mobile technology (a form of telehealth approaches) to deliver health-related education.
We collected data through a survey targeting a sample of 56 Egyptian patients aged between 25 and 65
years old in 2014.
Results: The results showed a promising acceptance rate (54%) among respondents; mostly those aged
between 25-35 years agreed to use mobile technology like Short Message Service (SMS) to deliver health-
related educational information to improve their self-managing experience and health outcomes.
Conclusion: We conclude that accompanying the rise in mobile phones subscription and willingness to
receive health-related SMS, mobile health presents an opportunity for health education programs,
especially when targeting younger adults.
Implications: These findings emphasize the potential to introduce more individualized, innovative and
engaging approaches to educate and leverage patients with their own health using technology in a
developing country. We recommend further studies to evaluate the effect of mobile-based patient
education on a sample of chronically diseased patients (e.g. diabetics patients) to measure the desired
outcomes such as lifestyle and self-care behaviours (medication adherence, improved knowledge,
satisfaction and quality of life).
Research Interests:
As the COVID-19 pandemic continues to disrupt health systems worldwide, conducting Rapid Antigen Testing (RAT) at specified intervals has become an essential part of many people’s lives around the world. We identified and analyzed the... more
As the COVID-19 pandemic continues to disrupt health systems worldwide, conducting Rapid Antigen Testing (RAT) at specified intervals has become an essential part of many people’s lives around the world. We identified and analyzed the academic literature on COVID-19 RAT. The Web of Science electronic database was queried on 6 July 2022 to find relevant publications. Publication and citation data were retrieved directly from the database. VOSviewer, a bibliometric software, was then used to relate these data to the semantic content from the titles, abstracts, and keywords. The analysis was based on data from 1000 publications. The most productive authors were from Japan and the United States, led by Dr. Koji Nakamura from Japan (n = 10, 1.0%). The most academically productive countries were in the North America, Europe and Asia, led by the United States of America (n = 266, 26.6%). Sensitivity (n = 32, 3.2%) and specificity (n = 23, 2.3%) were among the most frequently recurring auth...
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BackgroundCrowdsourcing is a low-cost, adaptable, and innovative method to collect ideas from numerous contributors with diverse backgrounds. Crowdsourcing from social media like Twitter can be used for generating ideas in a noticeably... more
BackgroundCrowdsourcing is a low-cost, adaptable, and innovative method to collect ideas from numerous contributors with diverse backgrounds. Crowdsourcing from social media like Twitter can be used for generating ideas in a noticeably brief time based on contributions from globally distributed users. The world has been challenged by the COVID-19 pandemic in the last several years. Measures to combat the pandemic continue to evolve worldwide, and ideas and opinions on optimal counteraction strategies are of high interest.ObjectiveThis study aimed to validate the use of Twitter as a crowdsourcing platform in order to gain an understanding of public opinion on what measures can help to end the COVID-19 pandemic faster.MethodsThis cross-sectional study was conducted during the period from December 22, 2021, to February 4, 2022. Tweets were posted by accounts operated by the authors, asking “How to faster end the COVID-19 pandemic?” and encouraging the viewers to comment on measures tha...
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The aim: This paper explores the documentation of the effect of quartan fever on, the ancient Greek equivalent of conditions falling nowadays under the spectrum of depression, in Greco-Roman medical sources. Materials and methods: The... more
The aim: This paper explores the documentation of the effect of quartan fever on, the ancient Greek equivalent of conditions falling nowadays under the spectrum of depression, in Greco-Roman medical sources. Materials and methods: The authors searched original medical texts written in Greek by physicians who lived and practiced Medicine in the broader Mediterranean region from the 5th century BC to the 7th century AD for records related to quartan fever and neuropsychiatric diseases. Conclusions: Quartan fever was used as a treatment for neuropsychiatric conditions until the middle of the 20th century. Although malaria can have severe neuropsychiatric sequelae, the neuroimmunological underpinnings of the effect of fever and heat on depression warrant further investigation.
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Introduction: Intense research on dementia has been conducted during the last years. As advances in the field have started changing the landscape of dementia treatment, it is necessary to assess the impact of novel therapeutic modalities.... more
Introduction: Intense research on dementia has been conducted during the last years. As advances in the field have started changing the landscape of dementia treatment, it is necessary to assess the impact of novel therapeutic modalities. Purpose: The current evidence about hypoxic – hyperoxic treatment for dementia is reviewed in this article. Methods: We conducted a thorough PubMed/MEDLINE and Google Scholar search. Results: Preclinical and clinical data are available. Hypoxic – hyperoxic treatment is encouraged in the context of the multimodal treatment of dementia. There are concerns about the recovery of memory with regard to specific modalities of this treatment. Future perspectives are highlighted in the light of potentially useful biomarkers and health policy. Conclusion: While constant updates and further research is critical to understand the impact of hypoxic – hyperoxic treatment in dementia, the available studies are limited and, hence, research that is more extensive i...
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Salvicine is a new diterpenoid quinone substance from a natural source, specifically in a Chinese herb. It has powerful growth-controlling abilities against a broad range of human cancer cells in both in vitro and in vivo environments. A... more
Salvicine is a new diterpenoid quinone substance from a natural source, specifically in a Chinese herb. It has powerful growth-controlling abilities against a broad range of human cancer cells in both in vitro and in vivo environments. A significant inhibitory effect of salvicine on multidrug-resistant (MDR) cells has also been discovered. Several research studies have examined the activities of salvicine on topoisomerase II (Topo II) by inducing reactive oxygen species (ROS) signaling. As opposed to the well-known Topo II toxin etoposide, salvicine mostly decreases the catalytic activity with a negligible DNA breakage effect, as revealed by several enzymatic experiments. Interestingly, salvicine dramatically reduces lung metastatic formation in the MDA-MB-435 orthotopic lung cancer cell line. Recent investigations have established that salvicine is a new non-intercalative Topo II toxin by interacting with the ATPase domains, increasing DNA–Topo II interaction, and suppressing DNA r...
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Introduction: Intense research on dementia has been conducted during the last years. As advances in the field have started changing the landscape of dementia treatment, it is necessary to assess the impact of novel therapeutic modalities.... more
Introduction: Intense research on dementia has been conducted during the last years. As advances in the field have started changing the landscape of dementia treatment, it is necessary to assess the impact of novel therapeutic modalities. Purpose: The current evidence about hypoxic – hyperoxic treatment for dementia is reviewed in
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Climate Change affects almost all life forms on earth during the evolutionary age of Anthropocene, the current age in which we live. Microorganisms form the basis of ancestral life forms and are crucial in our studies related to the cause... more
Climate Change affects almost all life forms on earth during the evolutionary age of Anthropocene, the current age in which we live. Microorganisms form the basis of ancestral life forms and are crucial in our studies related to the cause and impacts of climate change on a global scale. 'Microorganisms' are ascribed as any microscopic organism or virus not visible to the naked eye (smaller than 50 μm) that can exist in a unicellular, multicellular (for example, differentiating species), aggregate (for example, biofilm) or viral form. In addition to microscopic bacteria, archaea, eukaryotes, and viruses, we discuss certain macroscopic unicellular eukaryotes (for example, larger marine phytoplankton) and wood decomposing fungi.
Research Interests:
Research Interests:
There's a growing concern in the influence of climate change with temperatures worldwide affecting public health and well-being. Over 50 years of aggregated research data show that human activities mainly led to global warming caused... more
There's a growing concern in the influence of climate change with temperatures worldwide affecting public health and well-being. Over 50 years of aggregated research data show that human activities mainly led to global warming caused via the greenhouse effect of the high carbon dioxide (CO2) in the air. Such impact rises in the ambient temperature and creates massive climatic disruptions like eroding land from raised sea levels because of the melting of the Antarctic and Arctic ice, droughts, spike the extent of storms and hurricanes, and floods in several regions. Universally, such unfavorable outcomes have ongoing damaging influences on almost all nations, however higher on low-middle-income countries, with adverse effects on sustainability and development, including the health and well-being of millions of individuals. Lately, the effect of climate change on waterborne infectious diseases has become clearer. Intense climatic events like storms might contaminate the recreation...
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The future healthcare system will continue to have several electronic components. For example, using the Internet of Things (IoT) could enable the housed data both centrally, at the healthcare system level, and locally, at the patient... more
The future healthcare system will continue to have several electronic components. For example, using the Internet of Things (IoT) could enable the housed data both centrally, at the healthcare system level, and locally, at the patient level such as on a smartphone, to be critical components on selecting management approaches in a health-related condition. Producing medications and associated logistics is lagging far behind. For instance, cybersecurity and the needed strong public infrastructure are among the significant challenges. The cryptocurrency, a promising application of the blockchain technology, could revolutionize life sciences and biotechnology. The blockchain technique allows critical but lacking functionalities that are highly guarded and everlasting information housing, decentralizing and enhancing transaction transparency and incentivizing key stakeholders. A principal application of blockchain involves fighting fake medications with a focus on Cryptopharmaceuticals technology in which medications can be linked to a patient-specific blockchain of individual dosage units, where every manufactured dosage unit has a distinctive information-rich model using a smartphone application to visualize such blockchain at all levels. These cover producing personalized dosage units and patient views on their individual blockchain, and embedding such products into a healthy IoT system. Such a secured blockchain of individual medication history could avoid fake products and facilitates novel logistics. Hence, electronic ledgers could discover counterfeit drugs, facilitate virtual trials, and promote personalized medicine.
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The area of bioinformatics emerged as a method to promote biological research more than two decades ago. Bioinformatics is a multidisciplinary field of study composed of biology, mathematics, and computer science. It has emerged as a... more
The area of bioinformatics emerged as a method to promote biological research more than two decades ago. Bioinformatics is a multidisciplinary field of study composed of biology, mathematics, and computer science. It has emerged as a smoothing biological science instrument and saves findings as far as possible. Every day, enormous biological data are accessible to the science community by producing high throughput sequencing (HTS) technologies. Bioinformatics and algorithm approaches are now being used to evaluate such significant results. More scientifically, bioinformatics can be used to retrieve, mine, interpret and sort information with cross-linking references, which are accessible to help grasp biological complexities in this comprehensive natural archive and offer new insight.
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Worldwide water demand has been rising at a rate of 1% every year and expected to increase toward 30% by 2050. This, apart from the unsustainable pressures on freshwater which is just 2.5% of the total earth's surface, water is... more
Worldwide water demand has been rising at a rate of 1% every year and expected to increase toward 30% by 2050. This, apart from the unsustainable pressures on freshwater which is just 2.5% of the total earth's surface, water is under continuous degradation due to polluting discharges as a result of industrialization, urbanization, and chemical-based agriculture. Moreover, the brunt of climate change has made it a commodity scarcely available, with over two billion people experiencing high water stress in some countries. In such challenging times, with the Agenda – 2030 of the sustainable development goals on the one hand, and the extraordinary research on the other, has made a breakthrough means to the problem. The “means” is the “state of the art” technology on the “green synthesis” of nanoparticles (NPs) to degrade the organic as well as other toxic pollutants from the industrial wastewater. The “Green Synthesis” connotes high yielding biosynthesis of NPs using microorganisms like bacteria, fungi, algae, and plants. These are reliable, sustainable, eco-friendly, and with increased global average benefit-cost. These biogenic NPs with well-defined shape, size, and composition are developed by the method of a bottom-up approach. They undergo the systematic reactions of reduction or oxidation, producing microbial bio-enzymes or the phytochemicals of plants which are responsible for the reduction of metal salts and organic pollutants. They are biocompatible and are identified as hyper-accumulators of the pollutants with greater efficiency for detoxification. This chapter has reported various methods of development of these NPs and assessed their potentials in bioremediation to achieve the International goals.
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Abstract Derived from the roots of the plant Curcuma longa, curcumin (1, 7-bis (4-hydroxy-3-methoxyphenyl)-1, 6-heptadiene-3, 5-dione) is a natural, low molecular weight, polyphenolic compound. It is a yellow-orange colored polyphenol... more
Abstract Derived from the roots of the plant Curcuma longa, curcumin (1, 7-bis (4-hydroxy-3-methoxyphenyl)-1, 6-heptadiene-3, 5-dione) is a natural, low molecular weight, polyphenolic compound. It is a yellow-orange colored polyphenol non-toxic and bioactive agent found in turmeric. It has been in use for centuries as a household medication for several maladies. However, due to its low solubility, curcumin is unable to deliver in a proper manner and to be utilized for its medicinal resources. The present review illustrates the electrospinning of bioactive nanoparticles of curcumin on/within the electrospun nanofibers based on the type of biopolymers used. The encapsulation of bioactive nanoparticle curcumin is applied via the electrospinning process. Electrospinning consists of three major components, a power supply high-voltage, a spinneret, and a grounded collector. This technique has attracted much more attention for producing nanofibers with a diameter ranging from a few nanometers to several micrometers compared to other techniques used like nano-formulation, and emulsion process. Its high specific surface area and porosity enhances the dispersion and bioavailability of curcumin. The morphology of curcumin encapsulated as nano-formulates (nanoparticles, nanocapsules, nanorods, nanofibers) has been characterized using various techniques such as FE-SEM, TEM, X-ray Diffraction, FTIR, TGA/DTA respectively. While it’s antimicrobial activity against different pathogenic microbes has been determined for wound healing, burn infection, and antimicrobial resistance. The major worldwide health problem is bacterial resistance towards multidrug resistance pathogenic species. Hence, there is a constant need to develop new antibacterial/antifungal with novel mechanisms of action to overcome the problem of resistance. Many experimental data have reported the methoxy and hydroxyl groups found in curcumin structure are directly associated with antimicrobial activity/decrease in ergosterol of fungal cell membrane, signifying the electrospun nanofibers showing potential application as antibacterial/antifungal nonwoven mats and preventing fungal colonization on food products.
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Abstract The open innovation hub Digital Health and Patient Safety Platform (DHPSP) was recently established with the purpose to invigorate collaborative scientific research and the development of new digital products and personalized... more
Abstract The open innovation hub Digital Health and Patient Safety Platform (DHPSP) was recently established with the purpose to invigorate collaborative scientific research and the development of new digital products and personalized solutions aiming to improve human health and patient safety. In this study, we evaluated the effectiveness of a Twitter-based campaign centered on using the hashtag #DHPSP to promote the visibility of the DHPSP initiative. Thus, tweets containing #DHPSP were monitored for five weeks for the period 20.10.2020-24.11.2020 and were analyzed with Symplur Signals (social media analytics tool). In the study period, a total of 11,005 tweets containing #DHPSP were posted by 3,020 Twitter users, generating 151,984,378 impressions. Analysis of the healthcare stakeholder-identity of the Twitter users who used #DHPSP revealed that the most of participating user accounts belonged to individuals or doctors, with the top three user locations being the United States (501 users), the United Kingdom (155 users), and India (121 users). Analysis of co-occurring hashtags and the full text of the posted tweets further revealed that the major themes of attention in the #DHPSP Twitter-community were related to the coronavirus disease 2019 (COVID-19), medicine and health, digital health technologies, and science communication in general. Overall, these results indicate that the #DHPSP initiative achieved high visibility and engaged a large body of Twitter users interested in the DHPSP focus area. Moreover, the conducted campaign resulted in an increase of DHPSP member enrollments and website visitors, and new scientific collaborations were formed. Thus, Twitter campaigns centered on a dedicated hashtag prove to be a highly efficient tool for visibility-promotion, which could be successfully utilized by healthcare-related open innovation platforms or initiatives.
Research Interests: Business and Social Media
In December 2019, the coronavirus disease (COVID-19) was discovered in China, causing many cases and deaths. Several studies have explored the role of environmental factors in the spread of COVID-19, emphasizing the effect of two weather... more
In December 2019, the coronavirus disease (COVID-19) was discovered in China, causing many cases and deaths. Several studies have explored the role of environmental factors in the spread of COVID-19, emphasizing the effect of two weather parameters, humidity and temperature. Those parameters are evidently vital affecting outbreaks of infectious respiratory diseases, like influenza, yet such an effect on COVID-19 remains controversial. This review explores the relation between the change in weather-related factors and the transmission of the COVID-19. With seasonal variation from winter to summer and in the absence of adopting thorough public health measures, elevated temperature and humidity might not limit the COVID-19 cases. Hence, we need multidisciplinary strategies and interventions to limit the burden of this pandemic over the healthcare systems.
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A crucial element of cancer controlling programs for the expanding burden in Egypt is public awareness of preventable risk factors. The study explores the knowledge of some preventable risk factors and beliefs about cancer among adults... more
A crucial element of cancer controlling programs for the expanding burden in Egypt is public awareness of preventable risk factors. The study explores the knowledge of some preventable risk factors and beliefs about cancer among adults attending a primary health care center in an urban area of Alexandria. The researcher conducted a single point, a descriptive cross-sectional study of 85 adults aged ≥18 years in February 2019 using a semi-structured questionnaire to gather data through the face-to-face interviewing method. The data were analyzed by descriptive statistics. Good levels of both cancer knowledge and beliefs were assigned as ≥75% of the total score. Respondent's mean age was 43.6 years and around 64.7% were females. Nearly 74.1% of respondents had a poor knowledge score of cancer preventable risk factors, especially low vegetables and fruit consumption (55.3%) excessive exposure to sun radiations (52.9%), physical inactivity (44.7%), overweight and obesity (44.7%) and...
Research Interests:
Progress in computational sciences for cleaning, sorting, combining, digging, visualizing and managing data along with technological advancements in medical devices have urged needs for further extensive and consistent approaches to... more
Progress in computational sciences for cleaning, sorting, combining, digging, visualizing and managing data along with technological advancements in medical devices have urged needs for further extensive and consistent approaches to discuss the common key issues in medicine and health. Artificial Intelligence (AI) has significantly obtained grounds in everyday living in the era of information technology, and it has now landed in healthcare. AI studies’ in healthcare are evolving swiftly. However, it could only be the start of observing how it will influence patient care. AI tries to simulate human cognitive capacities. It is carrying a transformation pattern to healthcare, strengthened by the escalating availability of clinical data and sped up advancement in analytics systems. Nonetheless, there is a similar doubt, including some pressing warnings at these elevated anticipations. This review examines the present state of AI applications in health, major developments in health AI, a...
Research Interests:
For improving accomplished attempts to stop smoking, it is necessary to learn about the qualities of individuals who can willingly stop smoking. This study seeks to discover the willingness degree and associated determinants to stop... more
For improving accomplished attempts to stop smoking, it is necessary to learn about the qualities of individuals who can willingly stop smoking. This study seeks to discover the willingness degree and associated determinants to stop smoking between adult visitors of a primary healthcare centre in an urban area of Alexandria in Egypt. In this single point and descriptive cross-sectional study, a semi-structured questionnaire was distributed to a sample of 53 adults aged ≥18 years in May 2019. Descriptive statistical analyses were conducted to evaluate the determinants influencing the willingness to stop smoking. Of the 53 respondents (with a mean age of 38.7 years old), 41.5% of them were males. Almost 18.9% of the respondents were ongoing smokers (36.4% of males and 6.5% of females), though 83.7% of those smokers were willing to stop smoking. The number of male smokers was significantly greater than female smokers (Pearson Chi-Square = 7.52, p-value = 0.006). Determinants, which can...
Research Interests: Health Sciences, Behavioral Sciences, Preventive Health, Community Health, Egypt, and 12 morePreventive medicine, Health, Public Health, Attitudes (Social Psychology), Medicine, Smoking Cessation, Social Science Research Network, Smoking, Attitude, Community Health and Preventive Medicine, Medicine and Health Sciences, and Willingness to stop smoking
Similar to all fields of study, growth occurs with breakthrough or developmental research spanning to the progress and intimate utility of technology. Dilemmas of various sectors have been favorably resolved by adopting artificial... more
Similar to all fields of study, growth occurs with breakthrough or developmental research spanning to the progress and intimate utility of technology. Dilemmas of various sectors have been favorably resolved by adopting artificial intelligence (AI) algorithms. Applying Precision Medicine profoundly depends on AI algorithms to work Precision Medicine queries like; predicting or detecting, diagnosing the disease properly, and optimizing therapy, hence, the selection of the algorithm is affected by its capacity and practicality. Nevertheless, it is yet in its initial step and fronts some hurdles crucial to the flourishing deployment of precision medicine like research, adoption values, and authority controls. Notwithstanding, Precision Medicine also pretends some difficulties like; modifying the health discipline and profession to the fact that automata and algorithms could displace most of the healthcare professional tasks they act now. Ultimately, effective employment of precision me...
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Objectives: In Egypt, irrational medication use is a community concern. This study examines patients’ attitudes regarding medication use to promote rational medication use.Methods: In April 2019, a cross-sectional study involved 72... more
Objectives: In Egypt, irrational medication use is a community concern. This study examines patients’ attitudes regarding medication use to promote rational medication use.Methods: In April 2019, a cross-sectional study involved 72 patients attending a primary health care centre in Alexandria who responded to a face-to-face questionnaire.Results: The respondents’ mean age was 44.94 years and 56.94% of them were females. 77.78% of the respondents stated that when they get sick, they seek medications from the pharmacy without consulting a physician. Moreover, 52.78% of the respondents reported that their relatives recommend medications for them while 48.61% of them recommended medications themselves for their sick relatives. Additionally, 66.67% of the respondents stated that they stopped their medications prior to their physicians’ recommended time and 61.11% of them admitted keeping unused medications at home. 73.61% of the respondents reported reading medication’s prospectus and 75...
Research Interests: Pharmacy, Health Promotion, Primary Health Care, Family Medicine, Health, and 15 morePublic Health, Health Policy, Health Care Management, Attitude change, Medicine, Medication Management, Clinical Pharmacy, Patient education, Health and Social Care, Attitudes, Attitude, Beliefs and attitudes, Clinical Pharmacy Practice, Medication, and Medical Electronics
Antibiotic misuse and bacterial resistance is a significant public health concern worldwide. Egypt lacks policies and regulations concerning medication prescriptions. The study explores the knowledge and attitudes regarding antibiotic use... more
Antibiotic misuse and bacterial resistance is a significant public health concern worldwide. Egypt lacks policies and regulations concerning medication prescriptions. The study explores the knowledge and attitudes regarding antibiotic use and resistance among adults attending a primary healthcare centre in an urban area of Alexandria. The researcher conducted a single point, descriptive cross-sectional study on 87 adults aged ≥18 years attending a primary healthcare center in an urban area of Alexandria in January 2019 using a semi-structured questionnaire to gather data about the knowledge and attitudes of using antibiotics and resistance through the face-to-face interviewing method. The data were analyzed by descriptive statistics to explore the respondents’ level of knowledge with respect to the use of antibiotics and resistance. High level of knowledge was assigned as > 66.7% of the total score. About 52.8% of the respondents (63.2% of them were females) lack adequate knowled...
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Patient education includes multiple interventions for teaching patients about their health to improve their outcomes. The term has evolved to the more active terms (patient engagement and empowerment). Patients, who are diagnosed with... more
Patient education includes multiple interventions for teaching patients about their health to improve their outcomes. The term has evolved to the more active terms (patient engagement and empowerment). Patients, who are diagnosed with chronic diseases that cost patients lifelong treatmentand dangerous complications (e.g. Diabetes mellitus) need to be responsible for their health by self-management. With more computers and mobile devices owners globally, telehealth offers promising healthcare technology interventions to improve the patient’s health literacy.
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Good health and well-being are essential for a stronger society and a fundamental human right. Ill health is evidently associated with poverty. Egypt targets improving health services, despite the scarcity of financial resources, a... more
Good health and well-being are essential for a stronger society and a fundamental human right. Ill health is evidently associated with poverty. Egypt targets improving health services, despite the scarcity of financial resources, a growing population, and the need for better governance. The Ministry of Health has identified strategic objectives to be achieved by 2030, which primarily targets improving the health of citizens by providing and enhancing primary healthcare via awareness and preventive measures; and achieving comprehensive healthcare coverage for all citizens.Recently, Egypt has a new success story in managing hepatitis C virus (HCV). Egypt was among the top countries with a highly prevalent HCV. Eliminating HCV faced several obstacles including shortage in global funding for treatment, late diagnosis, insufficient data, and poor screening. Treating HCV in Egypt has been nationally prioritized with the rise of the highly effectivedirect-acting antivirals. Egypt implement...
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The world needs to decrease emissions from agriculture, and fossil fuels to halt global warming adequately. Animal-based meals are nourishing and very vital to livings and nutrition in developing nations, though they are a similarly... more
The world needs to decrease emissions from agriculture, and fossil fuels to halt global warming adequately. Animal-based meals are nourishing and very vital to livings and nutrition in developing nations, though they are a similarly incompetent source. Producing beef is growing further dynamic, yet forests are still being cut down. People state they desire to consume more plants, although eating beef is yet increasing. Consuming meat is among the main factors for global warming. Provided that the globally growing market for meat, and the severe effect of manufacturing meat on the planet, cutting down animal protein regarded as public health and food security concern. A future with sustainable food would need a variety of approaches from the farmer to the consumer. This review explores the relation between producing beef and the emission of greenhouse gases (GHGs) and the debate of consuming more or fewer resources. It also displays the beneficial impact of cutting down beef consumpt...
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Lately, misusing and counterfeiting pharmaceuticals in the drug supply chain have grown evidently worldwide, especially in the developing world. A pharmaceutical product is counterfeit when having a fake identity (ID) or origin. A flawed... more
Lately, misusing and counterfeiting pharmaceuticals in the drug supply chain have grown evidently worldwide, especially in the developing world. A pharmaceutical product is counterfeit when having a fake identity (ID) or origin. A flawed drug supply chain is among the major causes of counterfeiting pharmaceuticals either for the complexity of tracing pharmaceuticals, the lack of transparency, or exchanging limited or irrelevant data between all the entities during the transactions. The counterfeit drugs adversely influence both patients’ health and the economic status of the actual producers. Transforming the existing drug supply chain by applying monitoring techniques between the manufacturer and the consumer would address such issues. The blockchain technology applies a digital signature where each block has a unique crypto ID, ensuring solid management over possession. The Internet of Things (IoT)-integrated blockchain is a competently distributed ledger (DLT), which preserves an...
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In December 2019, the initially infected patient of the novel coronavirus disease (COVID-19) was discovered in China. Globally, the pandemic has disseminated in almost 216 countries and considerably influenced all aspects of life. The... more
In December 2019, the initially infected patient of the novel coronavirus disease (COVID-19) was discovered in China. Globally, the pandemic has disseminated in almost 216 countries and considerably influenced all aspects of life. The number of confirmed cases and deaths is 24,854,140 million, and 838,924 thousand, respectively, until August 31, 2020, and yet growing with no sign of control. Techniques for artificial intelligence (AI) and big data could contribute significantly in addressing the COVID-19 pandemic via various attracting solutions, ranging from monitoring the outbreak, detecting the viral infection to diagnosing and managing. This work focuses on the significant applications AI and big data in responding to the coronavirus pandemic where it describes AI and big data, applications, limitations, and recommendations to control the COVID-19. This work gives novel perspectives on how AI and big data have enhanced responding to the COVID-19.
An expanding need for nanotechnology in different enterprises may cause a vast situation scattering of nanoparticles in the coming years. The most widely recognized recuperation technique utilized so far includes using magnets to isolate... more
An expanding need for nanotechnology in different enterprises may cause a vast situation scattering of nanoparticles in the coming years. The most widely recognized recuperation technique utilized so far includes using magnets to isolate iron-containing nanoparticles from complex blends, including wastewater. A few strategies have additionally been produced for the extraction, partition, and re-utilization of costly gold nanoparticles from various fluids. Pollution of multiple contaminants similar to metal nanoparticles (MNPs), Cu, Ni, Zn, Cd Ag, Pb, etc. exists well known to cause toxicity on the aquatic ecosystem. Macrophytes like Trapa spp., Lemna spp., Eichhornia spp., Vallisneria spp., and Pistia spp., etc., will be used to remove the MNPs from the contaminated water in an eco-friendly and cost-effective way. Phytoremediation has been effectively actualized in various
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Abstract There's a growing concern in the influence of climate change with temperatures worldwide affecting public health and well-being. Over 50 years of aggregated research data show that human activities mainly led to global... more
Abstract There's a growing concern in the influence of climate change with temperatures worldwide affecting public health and well-being. Over 50 years of aggregated research data show that human activities mainly led to global warming caused via the greenhouse effect of the high carbon dioxide (CO2) in the air. Such impact rises in the ambient temperature and creates massive climatic disruptions like eroding land from raised sea levels because of the melting of the Antarctic and Arctic ice, droughts, spike the extent of storms and hurricanes, and floods in several regions. Universally, such unfavorable outcomes have ongoing damaging influences on almost all nations, however higher on low-middle-income countries, with adverse effects on sustainability and development, including the health and well-being of millions of individuals. Lately, the effect of climate change on waterborne infectious diseases has become clearer. Intense climatic events like storms might contaminate the recreational coastline waters, raising the danger of diarrhea and other waterborne infectious diseases. Polluting drinking water is an obvious reason for transmitting waterborne infectious diseases in intense water-associated climatic conditions. The plant system for treating water might become diminished because of massive rains. Climatic events affect insect vectors’ life cycle by influencing the reproduction and survival rates, habitat, prosperity, and transmission; similarly, it affects the proliferating and survival rates of the infectious agent inside the vector. This chapter explores climate change, effects on public health, and well-being, involving an expected rise of waterborne infectious diseases.
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Across the world, there is a critical expansion in digital technology through all fields, including health. Electronic health (e-Health) is the future of healthcare. E-Health could help in building better healthcare systems since it can... more
Across the world, there is a critical expansion in digital technology through all fields, including health. Electronic health (e-Health) is the future of healthcare. E-Health could help in building better healthcare systems since it can be adopted to enhance communications, train the health workforce, assist in job-related tasks and supervision. Additionally, precision medicine (PM), which is a modern approach in low and middle-income countries (LMICs), could facilitate addressing chronic diseases. Such techniques could promote innovative public health interventions that will improve population well-being worldwide to satisfy the indicators of sustainable development goal number-3 (SDG-3) that stresses on ensuring healthy lives and promoting welfare for all. However, e-Health data could be both a gain and a challenge for LMICs. A transformational and synergetic strategy is necessary to adopt these techniques as it would sustainably minimize the expanses of healthcare. Yet, national ...
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There's a growing concern in the influence of climate change with temperatures worldwide affecting public health and well-being. Over 50 years of aggregated research data show that human activities mainly led to global warming caused via... more
There's a growing concern in the influence of climate change with temperatures worldwide affecting public health and well-being. Over 50 years of aggregated research data show that human activities mainly led to global warming caused via the greenhouse effect of the high carbon dioxide (CO2) in the air. Such impact rises in the ambient temperature and creates massive climatic disruptions like eroding land from raised sea levels because of the melting of the Antarctic and Arctic ice, droughts, spike the extent of storms and hurricanes, and floods in several regions. Universally, such unfavorable outcomes have ongoing damaging influences on almost all nations, however higher on low-middle-income countries, with adverse effects on sustainability and development, including the health and well-being of millions of individuals. Lately, the effect of climate change on waterborne infectious diseases has become clearer. Intense climatic events like storms might contaminate the recreational coastline waters, raising the danger of diarrhea and other waterborne infectious diseases. Polluting drinking water is an obvious reason for transmitting waterborne infectious diseases in intense water-associated climatic conditions. The plant system for treating water might become diminished because of massive rains. Climatic events affect insect vectors’ life cycle by influencing the reproduction and survival rates, habitat, prosperity, and transmission; similarly, it affects the proliferating and survival rates of the infectious agent inside the vector. This chapter explores climate change, effects on public health, and well-being, involving an expected rise of waterborne infectious diseases.
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The area of bioinformatics emerged as a method to promote biological research more than two decades ago. Bioinformatics is a multidisciplinary field of study composed of biology, mathematics, and computer science. It has emerged as a... more
The area of bioinformatics emerged as a method to promote biological research more than two decades ago. Bioinformatics is a multidisciplinary field of study composed of biology, mathematics, and computer science. It has emerged as a smoothing biological science instrument and saves findings as far as possible. Every day, enormous biological data are accessible to the science community by producing high throughput sequencing (HTS) technologies. Bioinformatics and algorithm approaches are now being used to evaluate such significant results. More scientifically, bioinformatics can be used to retrieve, mine, interpret and sort information with cross-linking references, which are accessible to help grasp biological complexities in this comprehensive natural archive and offer new insight.