Research Interests:
Planetary ball milling assisted piezocatalysis for water cleaning application.
Research Interests:
Research Interests:
Research Interests:
Research Interests:
<span style="font-size:11.0pt;font-family: "Times New Roman";mso-fareast-font-family:"Times New Roman";mso-ansi-language: EN-US;mso-fareast-language:EN-US;mso-bidi-language:AR-SA" lang="EN-US">A search for precursors of earthquakes from multi-station ULF observations and TEC measurements in India...more
543-556Ground based observations have been carried out for ultra low frequency (ULF) precursors of earthquakes at four different stations in India, namely Agra (geographic lat 27°N, long 78°E), Guttu (lat 31.53°N, long 78.75°E), Shillong... more
543-556Ground based observations have been carried out for ultra low frequency (ULF) precursors of earthquakes at four different stations in India, namely Agra (geographic lat 27°N, long 78°E), Guttu (lat 31.53°N, long 78.75°E), Shillong (lat 25.92°N, long 91.88°E) and Kolhapur (lat 16.40°N, long 74.15°E) using identical 3-component search coil magnetometers (f = 0.01-30 Hz) obtained from Lviv Centre of Space Research, Ukraine. An offline analysis of the combined data has been carried out in relation to a major earthquake of magnitude M=7.9 occurred in the neighbouring country China (lat 31°N, long 103.32°E, depth=19 km) under the National Program of Earthquakes Precursors (NPEP) launched in India since May 2009. The results of the analysis show occurrence of amplitude anomalies as precursors whose amplitudes decrease with distance. The precursor periods range between 2 and 5 days and are large for the stations nearer to epicenter. A graphical determination of location of the epicen...
Research Interests:
Research Interests:
Research Interests:
Introduction- Acute Promyelocytic leukemia (APML) needs to be suspected early so that All-Trans Retinoic Acid (ATRA) therapy can be started as soon as possible. Flow cytometry shows absence of CD34 and HLADR in most cases and so can aid... more
Introduction- Acute Promyelocytic leukemia (APML) needs to be suspected early so that All-Trans Retinoic Acid (ATRA) therapy can be started as soon as possible. Flow cytometry shows absence of CD34 and HLADR in most cases and so can aid in diagnosis along with the usual morphological clues. However, it may have confusing patterns as in hypogranular APML and sometimes may be positive for HLA- DR and CD34. RT-PCR for detection of characteristic APML translocations (t(15;17),t(17;17) and others) is gold standard for APML diagnosis which is time consuming and often not possible especially in resource limited areas. Cytochemical MPO stain is a robust laboratory test that can be a valuable aid to morphology in early diagnosis of APML. In this study, the role of cytochemical MPO was evaluated for early diagnosis of APML. Method- This study included all the cases of APML that were diagnosed in a tertiary care center in India from May 2011 to May 2014. Cytochemical stains (MPO, Non- specific...
Research Interests:
Over the past few decades, the world has started moving towards renewable resources of energy from non-renewable resources for meeting today’s energy demand. The solar energy is available abundant in nature and easy to harvest it, and... more
Over the past few decades, the world has started moving towards renewable resources of energy from non-renewable resources for meeting today’s energy demand. The solar energy is available abundant in nature and easy to harvest it, and provides a natural solution to move ahead in fulfilling the energy requirement. The solar photovoltaic cells convert solar energy to electrical energy. In general, the regular PV module cell converts nearly about 5–18% of the incidental solar radiation into electricity, and in order to maintain energy balance nearly 60% of incidental radiations are converted in the form of heat energy and with scientific and experimental analysis; it is already pre-determined that with increase in internal PV cell temperature there is an exponential decrease in electrical efficiency of the solar cell gradually with this alternate cooling and superheating process over a time period thermal stresses are formed in solar cell which eventually degrades the cell. A practical way of marginally increasing the output efficiency of solar PV cell is to decrease the operating and surrounding temperature of solar PV, which can be achieved by maintaining a stipulated temperature when solar photovoltaic cell is in operation. Therefore, in the following work, a novel passive technique of cooling has been introduced by basic principles of evaporation using sand dunes concept of cooling and will be investigated experimentally.
Research Interests:
Research Interests:
Over the years, use of Online Social Networks (OSNs) has exploded and thus, causing a need of studying and understanding users' behavior online. The excessive use of online social networking causes a great increase in anomalies.... more
Over the years, use of Online Social Networks (OSNs) has exploded and thus, causing a need of studying and understanding users' behavior online. The excessive use of online social networking causes a great increase in anomalies. Anomalies in OSNs can signify irregular and often illegal behavior. Detection of such anomalies has been used to identify malicious individuals, including spammers, sexual predators and online fraudsters. For detecting the anomalies dataset of Twitter network is used and analyzed for user behavior via analyzing their tweets to find whether it is an anomalous or not.
Research Interests:
Electric Vehicles (EVs) are being increasingly seen as an eco-friendly alternative to conventional internal combustion vehicles. EVs require periodic charging of their batteries and fixed charging stations (FCSs) have been used commonly... more
Electric Vehicles (EVs) are being increasingly seen as an eco-friendly alternative to conventional internal combustion vehicles. EVs require periodic charging of their batteries and fixed charging stations (FCSs) have been used commonly to charge EV batteries. However, FCSs may not be able to charge many EVs during increased demands. Mobile charging stations (MCS) have been proposed for charging EVs at different spots, with an MCS carrying batteries travelling to the EV to charge its batteries. In this paper, we propose a framework for temporarily increasing the capacity of FCSs by scheduling MCSs to service additional EVs during increased demand. The problem of scheduling the MCSs to different FCSs based on EV charging demands is formulated, and is shown to be NP-hard. Two offline heuristic algorithms to solve the problem are proposed. Detailed simulation on a real-world map is presented to show that the algorithms perform well in realistic scenarios.
Research Interests:
Research Interests:
Research Interests:
Research Interests:
The DEMETER (Detection of Electromagnetic Emissions Transmitted from Earthquake Regions) satellite data have been analysed for a period of three and half months from 01 September to 16 December 2010 in search of whistlers and VLF... more
The DEMETER (Detection of Electromagnetic Emissions Transmitted from Earthquake Regions) satellite data have been analysed for a period of three and half months from 01 September to 16 December 2010 in search of whistlers and VLF emissions and their ground observations at low latitudes. The quick look data show intense sporadic bursts mostly in the Instrument Champ Electrique (ICE) channel of the satellite. These bursts are analysed using MATLAB software for the nighttime passes of upgoing orbits in the latitude range 20°-50°. The analysis shows records of large number of first component of magnetospherically reflected (MR) whistlers, mostly when the satellite is in low latitude ionosphere. These whistlers, together with normal whistlers observed in the satellite, are not observed on the ground as revealed by simultaneous ground observations at low latitude station Agra. This confirms them to be non-ducted whistlers which are reflected and observed in the ionosphere and magnetospher...
Research Interests:
Present paper includes performance study of a vertical Kaplan turbine using CFD analysis. The analysis is performed for single phase containing only water for steady state condition. The turbine performance is analyzed at BEP and part... more
Present paper includes performance study of a vertical Kaplan turbine using CFD analysis. The analysis is performed for single phase containing only water for steady state condition. The turbine performance is analyzed at BEP and part load points using CFD and it shows that the performance obtained is quite satisfactory for the BEP and part load conditions. Therefore, it can be concluded that CFD can be used as an effective tool during design cycle to reduce the time and cost and to enhance the product performance.
Research Interests:
This article deals with selection and performance evaluation of various piezoelectric materials for active vibration control (AVC) application. Finite element method is used to assess the relative importance of materials properties... more
This article deals with selection and performance evaluation of various piezoelectric materials for active vibration control (AVC) application. Finite element method is used to assess the relative importance of materials properties (Young's Modulus (E), piezoelectric constants (e31), dielectric constant (ε), density (ρ) and Poisson's ratio (υ)) for sensor and actuator applications which are eventually used in active vibration control. Analytical hierarchy process (AHP) is finally used to assign weights to all the properties understudy. Rankings made by multiple attribute decision matrix (MADM) approach show good agreement with finite element (FE) simulation results. The numerical simulations reveals the superior performance of K0.5Na0.5NbO3-LiSbO3-CaTiO3(KNN-LS-CT (1 wt. %)) as sensor followed by KNN-LS-CT (2 wt. %) and K0.475Na0.475Li0.05 (Nb0.92Ta0.05Sb0.03) O3 (KNLNTS). For actuator, Pb [ZrxTi1−x] O3 (PZT1) demonstrates the superior performance followed by KNLNTS and KNN-LS-CT (1 wt. %). The lead-free piezoelectric materials are potential candidate to replace lead-based piezoelectric materials for active vibration control application.
Research Interests:
ABSTRACT The article deals with finite element study of 1–3 composites made of piezoceramic fibers embedded in epoxy. The study focuses on evaluation of effective properties of piezoelectric fiber composites using representative volume... more
ABSTRACT The article deals with finite element study of 1–3 composites made of piezoceramic fibers embedded in epoxy. The study focuses on evaluation of effective properties of piezoelectric fiber composites using representative volume element method. The physical properties deduced are further used for analyzing sensing and actuation characteristics of unimorph cantilever beam. K0.5Na0.5NbO3-LiSbO3(KNN-LS), KNNLS doped with 1 wt% CaTiO3 [KNN-LS-CT (1 wt%)], K0.475Na0.475Li0.05(Nb0.92Ta0.05Sb0.03)O3 (KNLNTS), 0.885 (Bi0.5Na0.5)TiO320.05(Bi0.5K0.5)TiO320.015 (Bi0.5Li0.5)TiO3 20.05 BaTiO3(BNKLBT) and lead zirconate titanate (Pb[ZrxTi12x]O3) (PZT) are embedded in epoxy matrix to form 1–3 piezocomposites. K0.475Na0.475Li0.05(Nb0.92Ta0.05 Sb0.03)O3 (KNLNTS) shows excellent performance than other composites under study. It can be concluded that KNLNTS (lead-free piezoelectric material) is a potential candidate which can replace lead based PZT for smart structure applications.
Research Interests:
Research Interests: Dermatology, Medicine, Allergy, Humans, Anaphylaxis, and 12 moreCollagen, Laparoscopic Cholecystectomy-Analgesia, Female, Differential Diagnosis, Clinical Sciences, Middle Aged, Hemostasis, Eosinophilia, Laparoscopic Cholecystectomy, Postoperative Complications, Abdominal abscess, and Drug hypersensitivity
Employing a GPS receiver we have monitored ionospheric total electron content (TEC) at Agra (Geographic Lat. 27.2°N, Long. 78°E), India since 24 June, 2006. In this paper we have analysed 15 months of data for the period between 01... more
Employing a GPS receiver we have monitored ionospheric total electron content (TEC) at Agra (Geographic Lat. 27.2°N, Long. 78°E), India since 24 June, 2006. In this paper we have analysed 15 months of data for the period between 01 September, 2006 and 30 November, 2007 ...
Research Interests:
Research Interests:
Research Interests:
Intermittent electromagnetic radiation (EMR) emissions from metals and alloys during deformation under unrestricted quasi-static compression are reported in this paper. The end surface conditions of the compressing platens, whether... more
Intermittent electromagnetic radiation (EMR) emissions from metals and alloys during deformation under unrestricted quasi-static compression are reported in this paper. The end surface conditions of the compressing platens, whether lubricated or unlubricated, influence the EMR emission characteristics. The EMR emissions under compression show shape anisotropy. The first EMR emission invariably occurs near the yield. The EMR emission characteristics are also influenced by the crystal structure. During axial compression, dead metal zones formed on the top and bottom portions of the specimens possibly generate a climbing motion of edge dislocations in the radially outward mid-regions. During the climbing motion, these edge dislocations form accelerated electric line dipoles and emit electromagnetic radiation. These EMR emissions can be used to evaluate the degree of damage in metallic components under compression.
Research Interests:
Research Interests: Materials Engineering, Mechanical Engineering, Civil Engineering, Materials Science, Fracture, and 13 moreTitanium, Crack propagation, Electromagnetic Radiation, Accounts, Dislocation, Dislocations, Microstructures, Plastic deformation, Theoretical Model, Line Tension, Frequency spectrum, Metallic Materials, and Exponential Decay
Software security helps in identifying and managing risks. One of the effective ways to identify software vulnerabilities is to analyze its code. Code analysis Chess & West, 2007 helps in catching ...
Research Interests:
... India Anomalous Behavior of GPS Based Total Electron Content (TEC) Associated With Earthquakes OP Singh, Vishal Chauhan Department of Physics, Faculty of Engineering & Technology, RBS College, India. Vikram Singh ...
Research Interests:
The temporal and seasonal variations of Total Electron Content (TEC) are studied at Agra (Geographic Lat. 27.17?? N, Long. 78.89?? E, Dip: 41.4??), India, which is in the equatorial anomaly region, for a period of 12 months from 01... more
The temporal and seasonal variations of Total Electron Content (TEC) are studied at Agra (Geographic Lat. 27.17?? N, Long. 78.89?? E, Dip: 41.4??), India, which is in the equatorial anomaly region, for a period of 12 months from 01 January to 31 December, 2007 using a ...
Research Interests: Mechanical Engineering, Aerospace Engineering, Environmental Science, Remote Sensing, Morphology, and 15 moreGlobal Positioning System, Space, GPS, Ionosphere, Models, Space Research, Total Electron Content, Electron Density, Seasonal variation, Tec, Seasonal Variations, Agra, Summer, Perturbation, and Global position ing system
The present paper validates the hydraulic design of a metallic volute centrifugal pump (Nsq=76). CFD is used for numerical investigation of the entire pump and every component of the pump like metallic volute; diffuser, impeller, and... more
The present paper validates the hydraulic design of a metallic volute centrifugal pump (Nsq=76). CFD is used for numerical investigation of the entire pump and every component of the pump like metallic volute; diffuser, impeller, and draft tube are included in the analysis. Single phase, steady state incompressible flow is selected for the CFD analysis. Fluid flow behavior is studied in all components and losses are estimated. Pump performance is predicted at BEP (Best Efficiency Point) as well as at part load operations. The validation is done by comparing the CFD analysis results with the experimental test results and it shows a good agreement between both the results.
Authentication, Authorization, security and confidential information are number of foremost topics part in the Digital cyber - security Area. There are multiple solutions available in this virtualize cyber world that are presented to... more
Authentication, Authorization, security and confidential information are number of foremost topics part in the Digital cyber - security Area. There are multiple solutions available in this virtualize cyber world that are presented to user’s strength as per digital security. Username and password base are common factor authentication methods. The growing-up popularity with compliance of second factorized methods those driven by the improvement of privacy and security as per the requirement during this digitalization of technological trend. The recognition and success of digital security various measures are big deal to obsessed with simple convenience. Its need more and more implementation for the user privacy, data confidentiality and network security’s system. mainly focus on this research Article into dealing with and analysing the implications of security part of 3FA proposal model for additional security in way of systematic manner to improvements of digital security in web-base...
Research Interests:
Research Interests:
Research Interests:
Research Interests:
Rainfall variations in the Garhwal Himalaya, Uttarakhand were studied for a period of six years from 2008 to 2013. The rainfall data were obtained through a dense network of rain gauges installed by India Meteorological Department (IMD),... more
Rainfall variations in the Garhwal Himalaya, Uttarakhand were studied for a period of six years from 2008 to 2013. The rainfall data were obtained through a dense network of rain gauges installed by India Meteorological Department (IMD), New Delhi, are spreaded over seven districts of Uttarakhand, combined with the data from Wadia Institute of Himalayan Geology (WIHG) rain gauge located at Ghuttu, Garhwal Himalaya. The rainfall data of WIHG have a sampling interval of 15 min, while IMD provides district- wise rainfall measurements with monthly temporal resolution. Therefore, extreme events of rainfall which occurred in a short duration of time were observed using the rainfall data of WIHG. Similarly, daily diurnal variations of rainfall were also observed in these data. The seasonal variations and distribution of rainfall in different districts of the Garhwal region were seen in both WIHG and IMD datasets. An increasing trend of rainfall activity was seen from 2008 to 2013. Meterolo...
Research Interests:
Farm production is the result of the transformation of various resources such as human labour, bullock power, mechanical power, water for irrigation, seeds, manures and fertilizers, insecticides and pesticides and cultivation practices,... more
Farm production is the result of the transformation of various resources such as human labour, bullock power, mechanical power, water for irrigation, seeds, manures and fertilizers, insecticides and pesticides and cultivation practices, etc. As these all factor inputs are costly and scarce, the case for their efficient use is self-evident. Moreover, farm resource endowment and the extent of their use on farms has a direct bearing in determining the overall level of crop production. Therefore, it is necessary to study the extent and magnitude of various farm endowments prevailing on farms in different size classes in the study area.The study was conducted at Jubbal and Kotkhai block of district Shimla from where sample of 200 farmers of different holdings were collected to understand the input-output relationship for pears production and was analyized with the Cobb-Douglas production function. From the study we tried to understand the resource efficiency by calculating the elasticity...
Research Interests:
Research Interests:
Abstract The Fluidization behavior of coal ash particles was studied to establish fluidization parameters in a cylindrical bubbling fluidized bed. A series of experiments were carried out with different sizes of irregular coal ash... more
Abstract The Fluidization behavior of coal ash particles was studied to establish fluidization parameters in a cylindrical bubbling fluidized bed. A series of experiments were carried out with different sizes of irregular coal ash particles ranging from 1 mm to 3 mm at different bed heights at atmospheric pressure and room temperature (ca. 28 °C). Fluidization regimes of all selected coal ash particles were studied by varying flow rates of fluidization medium i.e., air. The change in bed height and pressure drop across the bed was carefully analyzed to see the effects of particle size and superficial gas velocity during fluidization. The minimum fluidization velocity (Umf), minimum bubbling velocity (Umb) and fluidization index for different sizes of ash particles in cold conditions were calculated. The validation of experimental values was supported by theoretical calculations. It was observed that the Umb is 1.5–1.8 times higher than the Umf at different bed heights (Hbed). No substantial deviation was found in Umf with the variations of Hbed at a particular mean particle diameter (dp). Finally, the fluidization index between 1.58 and 1.78 for coal ash particles of Geldart-D type (dp> 1000 µm) shows an ideal condition for fluidization.
Research Interests:
In the autumn of 2017 we entered the second year of our PhDs under the supervision of Professor Rajinder Dudrah and were tasked with organising a conference which sought to bring together the next generation of Bollywood scholars. It was... more
In the autumn of 2017 we entered the second year of our PhDs under the supervision of Professor Rajinder Dudrah and were tasked with organising a conference which sought to bring together the next generation of Bollywood scholars. It was a natural choice and fit for our research topics – Dalit representation in Bollywood is Vishal’s area of enquiry and white femininity in Bollywood is Alexandra’s. Beyond our immediate academic focus, it seemed timely, too. The MeToo movement was gaining momentum internationally, extending to India and Bollywood, and India was beginning to think about forthcoming elections in 2019. Representation in Bollywood was the obvious choice with so much rich social and political material to draw on. Our interest specifically were the contemporary representations that have emerged from the context of post-1990s Bollywood to the present moment. The impact of liberalisation has been profound, and India’s entertainment industry has sought to keep pace with global trends on the one hand and define and sustain ‘Indian’ cultural values on the other. These processes are very much part of contemporary Indian society and consequently reflected in the creation of film, too. It was exciting to receive submissions from around the world and to see the diverse areas of Bollywood scholarship that our contemporaries are engaged in. After a careful and strenuous review, we invited nine scholars from four regions of the world to join us in May 2018 at Birmingham City University. We were delighted that Professor Rachel Dwyer, who has been a significant an influence on our work as our supervisor Professor Dudrah, accepted and attended to give the keynote speech on ageing masculinity in Bollywood, examining the case of Salman Khan specifically. The conference was a success and forged a nascent network of emerging Bollywood scholars. Connections were made and friendships formed. It was exciting for a group of interdisciplinary scholars to meet, in-person, and share their research. It’s not often we get such an opportunity, so we are thankful to Professor Dudrah for his initial encouragement and constant support, to our secondary supervisor Professor John Mercer for his support, to Professor Dwyer for her excellent keynote contribution and feedback on the papers presented, to Professors Priya Jha and Anjali Roy for coming all the way from the US and India, respectively, to chair
Research Interests:
Research Interests:
ABSTRACT Electromagnetic radiation (EMR) from soft and hard PZT under the drop weight impact have been studied. Due to impact the PZT undergoes a deformation wave which causes oscillations of dipoles within the PZT which give rise to... more
ABSTRACT Electromagnetic radiation (EMR) from soft and hard PZT under the drop weight impact have been studied. Due to impact the PZT undergoes a deformation wave which causes oscillations of dipoles within the PZT which give rise to electromagnetic radiation. The peak EMR voltage and the average EMR energy release rate show a linearly increasing pattern with the height of impact suggesting that these parameters could be used for monitoring excessive deformation from the structures. EMR peak voltage and average EMR energy release rate obtained from the soft PZT SP-5A are 43.42% and 53.12% higher respectively from those obtained from the hard PZT SP-4 owing to the higher resistance offered by the hard PZT to the domain switching.
Research Interests:
Nasal Natural Killer (NK)/T cell lymphoma, commonly mentioned in the literature as Lethal Midline Granuloma (LMG) is an unusual pathology of the oro-maxillo-facial region characterized by aggressive and progressive destruction of the... more
Nasal Natural Killer (NK)/T cell lymphoma, commonly mentioned in the literature as Lethal Midline Granuloma (LMG) is an unusual pathology of the oro-maxillo-facial region characterized by aggressive and progressive destruction of the face, nose, palate and pharynx. This disease is now classified as a T-cell lymphoma based on modern cytogenetics, immunologic and molecular studies. However, it is mentioned in various literatures by various names. Here, we present one such clinically diagnosed, histopathologically and immunologically confirmed case of LMG, designated as NK/T cell lymphoma in a 56-year-old male. The uncommon presentation of NK/T cell lymphomas should be kept as a differential diagnosis for management of patients.
Strong-motion records of recent Gorkha Nepal earthquake (Mw 7.8), its strong aftershocks and seismic events of Hindu kush region have been analysed for estimation of source parameters. The Mw 7.8 Gorkha Nepal earthquake of 25 April 2015... more
Strong-motion records of recent Gorkha Nepal earthquake (Mw 7.8), its strong aftershocks and seismic events of Hindu kush region have been analysed for estimation of source parameters. The Mw 7.8 Gorkha Nepal earthquake of 25 April 2015 and its six aftershocks of magnitude range 5.3–7.3 are recorded at Multi-Parametric Geophysical Observatory, Ghuttu, Garhwal Himalaya (India) >600 km west from the epicentre of main shock of Gorkha earthquake. The acceleration data of eight earthquakes occurred in the Hindu kush region also recorded at this observatory which is located >1000 km east from the epicentre of Mw 7.5 Hindu kush earthquake on 26 October 2015. The shear wave spectra of acceleration record are corrected for the possible effects of anelastic attenuation at both source and recording site as well as for site amplification. The strong-motion data of six local earthquakes are used to estimate the site amplification and the shear wave quality factor (Qβ) at recording site. The frequency-dependent Qβ(f) = 124f0.98 is computed at Ghuttu station by using inversion technique. The corrected spectrum is compared with theoretical spectrum obtained from Brune’s circular model for the horizontal components using grid search algorithm. Computed seismic moment, stress drop and source radius of the earthquakes used in this work range 8.20 × 1016–5.72 × 1020 Nm, 7.1–50.6 bars and 3.55–36.70 km, respectively. The results match with the available values obtained by other agencies.
Research Interests:
Research Interests:
To fully estimate the burden of illness due to edentulism and establish valid treatment outcomes measures in this regard, it is equally important to study its psychosocial repercussions. The aim was to conduct a study to explore the... more
To fully estimate the burden of illness due to edentulism and establish valid treatment outcomes measures in this regard, it is equally important to study its psychosocial repercussions. The aim was to conduct a study to explore the emotional reactions to tooth loss, screen for current depressive symptoms and test for association between the two; among an edentulous Gujarati population. A total of 147 edentulous people visiting the Prosthodontics Department were surveyed. A questionnaire (based on previous studies) to test the emotional reactions to tooth loss and Nine Item-Patient Health Questionnaire to test for depression were used. The data were analyzed using the Chi-square (χ (2)) test with the help of SPSS v. 18.0 (IBM Corp., Armonk, NY, USA). Totally, 100 out of 147 edentulous people returned the questionnaire of which 58% experienced difficulties in accepting tooth loss and 37% felt unprepared for its effects. Those with difficulties accepting tooth loss had a greater effec...
Pumping is the process of adding energy to the fluid to move it from one point to another. The main task faced by an engineer while drawing a pump design is with meeting the ends with the economics and the hydraulic operating... more
Pumping is the process of adding energy to the fluid to move it from one point to another. The main task faced by an engineer while drawing a pump design is with meeting the ends with the economics and the hydraulic operating characteristics. Computational Fluid Dynamics (CFD) has been widely used in analysis of 3D complex fluid flows present inside the pump hydraulic passages. The hydraulic analysis of a Vertical Turbine pump is performed using CFX software. CFturbo software has been used to predict the initial design of pump geometry. The overall goal of this work is to study the streamline and contours of pressure and velocity in a Vertical Turbine pump (Impeller and Bowl). The hydraulic performance of the pump is affected by geometrical parameters like Eye Diameter, Impeller outlet diameter, impeller outlet width etc.
Research Interests:
Background: Several clinical trials have demonstrated that mineralocorticoid receptor antagonists (MRA) markedly reduce morbidity and mortality in patients with heart failure (HF) with reduced ejection fraction. Despite their benefits,... more
Background: Several clinical trials have demonstrated that mineralocorticoid receptor antagonists (MRA) markedly reduce morbidity and mortality in patients with heart failure (HF) with reduced ejection fraction. Despite their benefits, MRAs are associated with hyperkalemia potentially leading to hospitalization. The ACC/AHA guidelines recommend monitoring of serum potassium at 3, 7, 30, 60 and 90 days after initiation of MRA. Methods: We identified patients in the Veterans Health Care System from 2003 to 2013, with a diagnosis of HF who were started on an MRA. The incidence of hospitalization for hyperkalemia was measured at 3 days, 7 days, 14 days, 30 days, 60 days, 90 days and 1 year after the initiation of an MRA. Results: There were 179,541 patients identified with a diagnosis of HF and started on an MRA. Baseline characteristics for the patients included a mean age of 69.5 ±11.4, 98% male, 17% black, 48% with diabetes and 83% with hypertension. HF-related medications included a beta-blocker in 47%, an ACE inhibitor in 54%, ARB in 13%, and a loop diuretic in 58%. The baseline mean creatinine was 1.35±0.9 mg/dl. The incidence rate of hospitalization for hyperkalemia per 10,000 persons per month was 1.7 at 3 days, 3.3 at 7 days, 6.5 at 14 days, 8.3 at 30 days, 7.9 at 60 days, 6.6 at 90 days and 3.7 at 1 year. For those taking an ACEi or ARB (high risk group, n=113,678, 63.3%), the incidence rate was 0.9 at 3 days, 3.4 at 7 days, 7.4 at 14 days, 10.1 at 30 days, 10.1 at 60 days, 8.3 at 90 days and 4.7 days at 1 year. The prevalence of moderate hyperkalemia (k ≥ 5.5) among 65,641 monitored within 14 days after MRA initiation was 7.1% and that of severe hyperkalemia (k ≥ 6.0) among 85,220 monitored within 30 days after MRA initiation was 3.2%. Conclusions: The incidence rate of hospitalization for hyperkalemia in this study peaked at 30 days after MRA initiation but was very low overall. Future studies to optimize the frequency of monitoring, while maintaining low rates of serious hyperkalemia may be warranted.