The identification of quantitative trait loci (QTL) and marker-assisted selection have aroused great interest in breeding programs aiming at fruit quality. The objective of this study was to detect QTL related to the quality of the cashew... more
The identification of quantitative trait loci (QTL) and marker-assisted selection have aroused great interest in breeding programs aiming at fruit quality. The objective of this study was to detect QTL related to the quality of the cashew apple. The physicochemical characteristics oligomeric phenolics, total soluble solids, total titrable acidity and vitamin C contents were analyzed in the mapped cashew population. QTL were detected by QTL interval and multiple QTL mapping. The results showed high phenotypic variation in the segregating F1 generation for all traits. Eighteen QTL associated with cashew quality were identified: three for oligomeric phenolics, five for total soluble solids, six for total acidity and four for vitamin C. QTL are promising for marker-assisted selection since they have the greatest phenotypic effects and contribution to phenotypic variation.
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Research Interests: Cystic Fibrosis, Adolescent, Medicine, Humans, Pulmonary fibrosis, and 15 moreImmunosuppression, Lung, Middle Aged, Adult, Emphysema, Chronic obstructive pulmonary disease, Idiopathic Pulmonary Fibrosis, Graft Rejection, Heart and Lung Transplantation, Proportional Hazards Models, Postoperative Complications, Lung Transplantation, Lymphoproliferative disorders, Cause of death, and Pulmonary Disease Chronic Obstructive
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We consider whether any two triangulations of a polygon or a point set on a non-planar surface with a given metric can be transformed into each other by a sequence of edge flips. The answer is negative in general with some remarkable... more
We consider whether any two triangulations of a polygon or a point set on a non-planar surface with a given metric can be transformed into each other by a sequence of edge flips. The answer is negative in general with some remarkable exceptions, such as polygons on the cylinder, and on the flat torus, and certain configurations of points on the cylinder.
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Research Interests: Cystic Fibrosis, Adolescent, Medicine, Humans, Child, and 15 moreCOPD, Female, Male, Aged, Middle Aged, Adult, Forced Vital Capacity, Mechanical Ventilation, Chronic obstructive pulmonary disease, Bronchiectasis, Idiopathic Pulmonary Fibrosis, Bronchiolitis Obliterans, Child preschool, Lung Transplantation, and Medical and Health Sciences
Abstract. Previous studies have shown that there is an intricate rela-tionship between the topology of an idiotypic network and its resulting properties. However, empirical studies can only be performed by pre-selecting both a shape-space... more
Abstract. Previous studies have shown that there is an intricate rela-tionship between the topology of an idiotypic network and its resulting properties. However, empirical studies can only be performed by pre-selecting both a shape-space and affinity function. This introduces a number of ...
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Research Interests: Mathematics, Computer Science, Combinatorics, Finite element method, Pure Mathematics, and 15 moreTriangulation, Key words, Dissection, Efficiency, Size, Numerical Analysis and Computational Mathematics, Differential equation, Point of View, Dcg, Cube, Simplexity, Simplex, Polytope, Asymptotic Efficiency, and fixed point
Additionally, we propose the study of combinatorial pseudo-triangulations on closed surfaces.
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... A 455 413 37 2898 Page 7. 642 R Crespo and FD Santos [7] Austern N, Iseri Y, Kamimura M, Kawai M, Rawitscher G and Yahiro M 1987 Phys. Rep. ... Reu. C 16 80 [13] Negele J W 1970 Phys. Rev. C 1 1260 [14] McGee IJ 1966 Phys. Reu. 151... more
... A 455 413 37 2898 Page 7. 642 R Crespo and FD Santos [7] Austern N, Iseri Y, Kamimura M, Kawai M, Rawitscher G and Yahiro M 1987 Phys. Rep. ... Reu. C 16 80 [13] Negele J W 1970 Phys. Rev. C 1 1260 [14] McGee IJ 1966 Phys. Reu. 151 772 [15] Johnson RC 1962 Nucl. ...
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Abstract. Idiotypic network models of the immune system have long attracted interest in immunology as they offer a potential explanation for the maintenance of immunological memory. They also give a possi-ble justification for the... more
Abstract. Idiotypic network models of the immune system have long attracted interest in immunology as they offer a potential explanation for the maintenance of immunological memory. They also give a possi-ble justification for the appearance of tolerance for a certain category of cells ...
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Research Interests: Mathematics, Combinatorics, Topology, Pure Mathematics, HOMOTOPY, and 4 morePolytopes, Matroid, Polytope, and Corollary
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La presente normativa ha sido elaborada con el consenso de, al menos, un representante de cada uno de los hospitales con programa de trasplante pulmonar en España. Además, previamente a su publicación, ha sido revisada por un grupo de... more
La presente normativa ha sido elaborada con el consenso de, al menos, un representante de cada uno de los hospitales con programa de trasplante pulmonar en España. Además, previamente a su publicación, ha sido revisada por un grupo de revisores destacados por su reconocida trayectoria en el campo del trasplante pulmonar. En las siguientes páginas, el lector encontrará los criterios de selección de pacientes candidatos a trasplante pulmonar, cuándo y cómo remitir un paciente a un centro trasplantador y, finalmente, cuándo incluir al paciente en lista de espera. Se ha atribuido un nivel de evidencia a las cuestiones más relevantes. Este documento pretende ser una guía práctica para los neumólogos que no participan directamente en el trasplante pulmonar pero que deben considerar este tratamiento para sus pacientes. Finalmente, se ha propuesto de una forma consensuada un documento que recoge de forma estructurada los datos del paciente potencial candidato a trasplante pulmonar que son relevantes para poder tomar la mejor decisión.The present guidelines have been prepared with the consensus of at least one representative of each of the hospitals with lung transplantation programs in Spain. In addition, prior to their publication, these guidelines have been reviewed by a group of prominent reviewers who are recognized for their professional experience in the field of lung transplantation. Within the following pages, the reader will find the selection criteria for lung transplantation candidates, when and how to remit a patient to a transplantation center and, lastly, when to add the patient to the waiting list. A level of evidence has been identified for the most relevant questions. Our intention is for this document to be a practical guide for pulmonologists who do not directly participate in lung transplantations but who should consider this treatment for their patients. Finally, these guidelines also propose an information form in order to compile in an organized manner the patient data of the potential candidate for lung transplantation, which are relevant in order to be able to make the best decisions possible.
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We consider whether any two triangulations of a polygon or a point set on a non-planar surface with a given metric can be transformed into each other by a sequence of edge flips. The answer is negative in general with some remarkable... more
We consider whether any two triangulations of a polygon or a point set on a non-planar surface with a given metric can be transformed into each other by a sequence of edge flips. The answer is negative in general with some remarkable exceptions, such as polygons on the cylinder, and on the flat torus, and certain configurations of points on the cylinder.
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Research Interests: Cystic Fibrosis, Adolescent, Medicine, Humans, Child, and 15 moreCOPD, Female, Male, Aged, Middle Aged, Adult, Forced Vital Capacity, Mechanical Ventilation, Chronic obstructive pulmonary disease, Bronchiectasis, Idiopathic Pulmonary Fibrosis, Bronchiolitis Obliterans, Child preschool, Lung Transplantation, and Medical and Health Sciences
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Research Interests: Psychology, Cognitive Science, Artificial Intelligence, Multiagent Systems, Mirror Neurons, and 15 moreEvolution of Morality, Social Cognition, Organizational Commitment, Intentionality, Evolutionary Game Theory, Evolution of Cognition, Acceptance and Commitment Therapy, Evolution and Human Behavior, Commitment Trust Theory, Joint Action, Imitation, Intention Recognition, Concepts of Simulation, Reference of Mental Concepts, and The Embodiment
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Using an animal model, we performed a study to assess the effects of rapid freezing in the absence of cryoprotectants on the viability of tracheal grafts after allotransplantation. Ten tracheal heterotopic transplantations were performed... more
Using an animal model, we performed a study to assess the effects of rapid freezing in the absence of cryoprotectants on the viability of tracheal grafts after allotransplantation. Ten tracheal heterotopic transplantations were performed with fresh grafts just after harvesting donors, and 20, with cryopreserved specimens at 2 or 6 weeks after hypothermic storage. Cryopreservation consisted of rapid cooling in the absence of cryoadditives with storage for 2 weeks at -80°C. After rewarming, grafts were transplanted into the abdominal cavity of immunosuppressed rats by being embedded into the greater omentum. Fourteen days later, the implants were removed to examine chondrocyte viability, submucosal swelling, and epithelial patterns in comparison with fresh controls. All allografts retained their macroscopic structure after transplantation. Respiratory epithelium was substituted by planar epithelium only in the frozen transplanted specimens. Fresh transplanted grafts exhibited 100% chondral viability in contrast with 5% viability observed among cryopreserved tracheas after transplantation. The method of rapid freezing was effective to preserve airway grafts. However, the quality of cryopreserved cartilage was disappointing, similar to that obtained using conventional slow-freezing protocols.
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Research Interests: Collective Behavior, Computer Science, Artificial Intelligence, Game Theory, Human Evolution, and 15 moreCognition, Cooperation (Evolutionary Psychology), Cooperation and Conflict, Social Cognition, Complex Systems, Organizational Commitment, Intentionality, Evolution, Evolutionary Game Theory, Evolution of Cognition, Social Evolution, Cooperation, Multi Agent System, Intention Recognition, and Self Organization
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Extended donors (EDs) are safely used to increase the donor pool in lung transplantation (LT), but their influence in critically ill patients (extended recipients [ERs]) remains controversial. We compared LT outcomes matching optimal... more
Extended donors (EDs) are safely used to increase the donor pool in lung transplantation (LT), but their influence in critically ill patients (extended recipients [ERs]) remains controversial. We compared LT outcomes matching optimal donors (ODs) or EDs with optimal recipients (ORs) or ERs. Three hundred and sixty-five LTs were reviewed. ED criteria: age >55, PaO2/FiO2 < 350 mmHg, pulmonary infiltrates/purulent secretions and ischaemic times >6 h (single LT [SLT]) and >9 h (double LT [DLT]). ER criteria: pulmonary fibrosis or pulmonary hypertension, pretransplant intubation, age >60 years and bypass…
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OBJETIVO: Avaliar se o procedimento cirúrgico com descompressão posterior sem artrodese da coluna lombar traz benefícios em avaliações prospectivas de dor e incapacidade. MÉTODOS: Dezesseis pacientes foram avaliados através de... more
OBJETIVO: Avaliar se o procedimento cirúrgico com descompressão posterior sem artrodese da coluna lombar traz benefícios em avaliações prospectivas de dor e incapacidade. MÉTODOS: Dezesseis pacientes foram avaliados através de questionários de incapacidade e dor no período pré-operatório e durante o seguimento pós-operatório de um mês, seis meses e um ano, tendo sido realizada cirurgia de descompressão sem instrumentação pedicular ou artrodese. RESULTADOS: Foram observadas melhoras nos medidores de dor e incapacidade durante o seguimento de um ano pós-operatório em relação aos valores iniciais. CONCLUSÃO: A descompressão sem artrodese em pacientes com estenose de canal lombar demonstrou ser eficaz na melhora da dor e incapacidade em pacientes selecionados no seguimento de um ano pós-operatório.
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Objective: To define the sagittal balance and spinopelvic parameters in a Brazilian population sample composed of asymptomatic volunteers. Methods: Fifty healthy adult individuals volunteered to participate in this study. The exclusion... more
Objective: To define the sagittal balance and spinopelvic parameters in a Brazilian population sample composed of asymptomatic volunteers. Methods: Fifty healthy adult individuals volunteered to participate in this study. The exclusion criteria included spinal deformity or improper radiograph study. In each radiograph exam in profile view, the sagittal balance and spinopelvic parameters were evaluated, including vertical sagittal axis, sacral slope, pelvic tilt and pelvic incidence. Results: The data obtained in this study are according to the values presented in the worldwide literature. None of the radiographic parameters showed any differences between the genders. Comparing the values presented in this study with those of other reports, with different populations, it was observed that: there was no significant difference in any of the pelvic parameters between Brazilian and Korean populations; there was a significant difference in pelvic incidence between Brazilian and European p...
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Research Interests: Flow Cytometry, Biology, Cell Biology, Medicine, Cell Differentiation, and 15 moreHumans, Genetic Enhancement, Gene transfer techniques, Liposomes, Bone marrow, Mesenchymal Stem Cell, Gene Delivery, Middle Aged, Adult, Adipocytes, Cell Proliferation, Cations, Mesenchymal Stromal Cells, Bone Marrow Cells, and Genetic Therapy
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The Spanish Lung Transplant Registry (SLTR) began its activities in 2006 with the participation of all the lung transplantation (LT) groups with active programs in Spain. This report presents for the first time an overall description and... more
The Spanish Lung Transplant Registry (SLTR) began its activities in 2006 with the participation of all the lung transplantation (LT) groups with active programs in Spain. This report presents for the first time an overall description and results of the patients who received lung transplants in Spain from 2006 to 2010. LT activity has grown progressively, and in this time period 951 adults and 31 children underwent lung transplantation. The mean age of the recipients was 48.2, while the mean age among the lung donors was 41.7. In adult LT, the most frequent cause for lung transplantation was emphysema/COPD, followed by idiopathic pulmonary fibrosis, both representing more than 60% the total number of indications. The probability for survival after adult LT to one and three years was 72% and 60%, respectively, although in patients who survived until the third month post-transplantation, these survival rates reached 89.7% and 75.2%. The factors that most clearly influenced patient surv...
Research Interests: Cystic Fibrosis, Adolescent, Medicine, Humans, Pulmonary fibrosis, and 15 moreImmunosuppression, Lung, Middle Aged, Adult, Emphysema, Chronic obstructive pulmonary disease, Idiopathic Pulmonary Fibrosis, Graft Rejection, Heart and Lung Transplantation, Proportional Hazards Models, Postoperative Complications, Lung Transplantation, Lymphoproliferative disorders, Cause of death, and Pulmonary Disease Chronic Obstructive
OBJETIVO: Avaliar os resultados do bloqueio facetário lombar com anestésico local e corticóide em pacientes com lombalgia crônica por síndrome facetária. MÉTODOS: Realizou-se um estudo prospectivo em 30 pacientes com lombalgia crônica por... more
OBJETIVO: Avaliar os resultados do bloqueio facetário lombar com anestésico local e corticóide em pacientes com lombalgia crônica por síndrome facetária. MÉTODOS: Realizou-se um estudo prospectivo em 30 pacientes com lombalgia crônica por síndrome facetária, os quais foram submetidos à infiltração facetária com bupivacaína a 0,25% e acetato de metilpredinisolona sob controle radioscópico, e foram seguidos e avaliados seguindo as escalas Visual Analógica da Dor, Oswestry Disability Index e os Critérios de MacNab nos quais 17 foram do sexo feminino e 13 do sexo masculino. RESULTADOS: Foi observada diminuição significativa (p<0,05) da dor pela Escala Visual Analógica. Obtivemos 73,3% de resultados satisfatórios na primeira semana, 63,3% no primeiro mês, 43,3% em 3 meses, e 36,6% no final de 6 meses. O índice de complicações foi muito baixo. CONCLUSÃO: O bloqueio facetário utilizando corticóide e anestésico local se mostrou-se efetivo, seguro e de fácil realização. No entanto houve r...