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Ravi Shekhar

    Ravi Shekhar

    • Mr. Ravi Shekhar is currently pursuing his MBA in Risk from Faculty of Commerce, BHU where as he is a experience prof... moreedit
    Background: Nicotine is the most used toxic substance in spite of mass media awareness. Column used in the estimation of nicotine is found to be the inhibiting factor for its estimation.Objective: To develop a method for nicotine... more
    Background: Nicotine is the most used toxic substance in spite of mass media awareness. Column used in the estimation of nicotine is found to be the inhibiting factor for its estimation.Objective: To develop a method for nicotine estimation on C8 column in HPLC.Methods: The method involved a model Waters 1515 binary HPLC Pump system interfaced with a 2489 Waters UV/VIS detector, a 4.6 X 250 mm, 5μm beads Symmetry C8 column at 37°C, and an isocratic mobile phase containing 60%: 40% v/ v mixture of 10mM sodium acetate (pH 5.5) and methanol at a flow rate of 1.0ml/min at 256 nm. The method was validated for specificity, linearity, precision, accuracy, the Limit of Detection (LOD), the Limit of Quantitation (LOQ) and system suitability.Results: The HPLC Nicotine peak with average retention time of 3.415 minutes was observed on chromatogram with RSD <0.5%; linearity was greater than 0.99 with acceptable precision (within USP limits of <2.0% RSD) and USP tailing less than 2. LOD was...
    We present a system for zero-shot crosslingual offensive language and hate speech classification. The system was trained on English datasets and tested on a task of detecting hate speech and offensive social media content in a number of... more
    We present a system for zero-shot crosslingual offensive language and hate speech classification. The system was trained on English datasets and tested on a task of detecting hate speech and offensive social media content in a number of languages without any additional training. Experiments show an impressive ability of both models to generalize from English to other languages. There is however an expected gap in performance between the tested cross-lingual models and the monolingual models. The best performing model (offensive content classifier) is available online as a REST API
    Docker is a platform which can contain ‘N’ number of container. Each container internallyis an Encapsulation of Linux kernel feature i.e. namespaces and cgroup. Isolating the process from other process in the same server can be achieved... more
    Docker is a platform which can contain ‘N’ number of container. Each container internallyis an Encapsulation of Linux kernel feature i.e. namespaces and cgroup. Isolating the process from other process in the same server can be achieved using Namespace isolation. It is done so that it can't see certain portion of overall system. Control groups as its name describes it controls the process, memory and CPU. It also keeps track of used memory. Multiple containers are present on a Docker hub each is having its own virtual environment. It is like a multi tenancy where the Containers are shared through same host kernel but each of it has their own virtualized network adapter and filesystem. It allows to develop, deployment and management applications in efficient manner. Docker containers are developed using Go Language. Go language is used to provision to support system programming to the container. Containers are light weighted and portable, as said it is an encapsulation of an environment in which the application is to be to run. Containers are created from images. Itcontains all dependencies and binaries need for an application to run. Containerization is the new way to build, ship and deploy applications. To create a container with minimal storage is a challenging task. Here in this paper we have tried to show how to create a Docker container with minimal storage.
    We augment a task-oriented visual dialogue model with a decision-making module that decides which action needs to be performed next given the current dialogue state, i.e. whether to ask a follow-up question or stop the dialogue. We show... more
    We augment a task-oriented visual dialogue model with a decision-making module that decides which action needs to be performed next given the current dialogue state, i.e. whether to ask a follow-up question or stop the dialogue. We show that, on the GuessWhat?! game, the new module enables the agent to succeed at the game with shorter and hence less error-prone dialogues, despite a slightly decrease in task accuracy. We argue that both dialogue quality and task accuracy are essential features to evaluate dialogue systems.1
    Central nervous system (CNS) stimulants are drugs, which produce a response that could be used to alleviate a particular medical condition. These are the agents, which speed up to treat conditions characterized by lack of adrenergic... more
    Central nervous system (CNS) stimulants are drugs, which produce a response that could be used to alleviate a particular medical condition. These are the agents, which speed up to treat conditions characterized by lack of adrenergic stimulation, including narcolepsy and neonatal apnea. The majority of CNS stimulants is chemically similar to the neurohormone norepinephrine and simulates the traditional "fight or flight" syndrome associated with sympathetic nervous system arousal. A small figure of added members of the CNS stimulant class do not fall into definite chemical groups. The review on central nervous system stimulants gives detail study of CNS stimulant drugs, their mechanism of action and in vivo models of CNS stimulants. The brain is a delicate tissue, and advancement built very effective methods to guard it. Unfortunately, the same mechanisms that protect it against intrusive chemicals can also upset therapeutic interventions. Many current medications are render...
    The correlation between increased West African monsoon rainfall and anomalously low surface pressure over the Sahara is well established in observations and global climate models, and has been interpreted as a strengthening of the Saharan... more
    The correlation between increased West African monsoon rainfall and anomalously low surface pressure over the Sahara is well established in observations and global climate models, and has been interpreted as a strengthening of the Saharan Heat Low (SHL) during wet monsoon years. This study uses two atmospheric reanalysis datasets to examine interannual variability of Sahel rainfall and the shallow Saharan Heat Low circulation, which consists of the near surface SHL and the Saharan High in the lower mid-troposphere. During wet Sahel years, the SHL circulation shifts poleward, producing a drop in low-level geopotential height and surface pressure over the Sahara. Statistically removing the effect of the poleward shift from the low-level geopotential eliminates significant correlations between this geopotential and Sahel precipitation. As the SHL circulation shifts poleward, its mid-tropospheric divergent outflow decreases, indicating a weakening of its overturning mass flux. The polew...
    The last years have seen an explosion of work on the integration of vision and language data. New tasks like Image Captioning and Visual Questions Answering have been proposed and impressive results have been achieved. There is now a... more
    The last years have seen an explosion of work on the integration of vision and language data. New tasks like Image Captioning and Visual Questions Answering have been proposed and impressive results have been achieved. There is now a shared desire to gain an in-depth understanding of the strengths and weaknesses of those models. To this end, several datasets have been proposed to try and challenge the state-of-the-art. Those datasets, however, mostly focus on the interpretation of objects (as denoted by nouns in the corresponding captions). In this paper, we reuse a previously proposed methodology to evaluate the ability of current systems to move beyond objects and deal with attributes (as denoted by adjectives), actions (verbs), manner (adverbs) and spatial relations (prepositions). We show that the coarse representations given by current approaches are not informative enough to interpret attributes or actions, whilst spatial relations somewhat fare better, but only in attention m...
    A new approach to zero- order drug delivery that includes geometric factors is described. Systems such as multilayered tablets and other geometrically altered devices have been created to perform this function. The multi-layered matrix... more
    A new approach to zero- order drug delivery that includes geometric factors is described. Systems such as multilayered tablets and other geometrically altered devices have been created to perform this function. The multi-layered matrix system overcomes inherent disadvantages of non-linearity associated with diffusion controlled matrix devices by providing additional release surface with time to compensate for the decreasing release rate. These formulations designed to deliver the drug at predetermined rate, maintain therapeutically effective concentrations in systemic circulation for prolonged period of time. Recently, pharmaceutical research has focused on controlled drug delivery offer definite advantages over conventional release formulation of the same drug. Controlled delivery systems that can provide zero-order drug delivery have the potential for maximizing efficacy while minimizing dose frequency and toxicity. In the present study, guar gum was used as hydrophilic matrix car...
    ABSTRACT The sequestration of CO2 into geologic formations, specifically existing and depleted oil and gas reservoirs, is a promising solution for reducing environmental hazards from the release of greenhouse gases into the... more
    ABSTRACT The sequestration of CO2 into geologic formations, specifically existing and depleted oil and gas reservoirs, is a promising solution for reducing environmental hazards from the release of greenhouse gases into the earth's atmosphere. A critical component of long-term sequestration will be our ability to adequately monitor the movement of CO2 fronts in the subsurface. In this article, we examine the viability of time-lapse seismic monitoring using an integrated modeling of fluid flow, including chemical reactions and seismic response. Modeling of CO2 injection is complicated by the various interactions between CO2, reservoir fluids, and the minerals in the formation. These interactions change fluid and bulk rock properties with time, which in turn impact the seismic signatures. We perform a comprehensive simulation of the gas injection process accounting for the phase behavior of CO2-reservoir fluids, the associated precipitation/dissolution reactions, and the accompanying changes in porosity and permeability. The simulation results are then used to model the changes in seismic response with time. The general observation is that gas injection decreases bulk density and wave velocity of the host rock system. Seismic amplitude attributes therefore change with time as well, and these effects provide a tool for tracking the movement of the CO2 front. Analysis of the results also confirms that much of the change can be attributed to chemical effects that should therefore be considered in studies of long-term sequestration projects.
    ABSTRACT An attempt was made to deposit a nanocoating onto a cotton textile substrate using a layer-by-layer self-assembly approach. Chitosan, a natural biopolymer with polycationic characteristic, was used as a polyelectrolyte along with... more
    ABSTRACT An attempt was made to deposit a nanocoating onto a cotton textile substrate using a layer-by-layer self-assembly approach. Chitosan, a natural biopolymer with polycationic characteristic, was used as a polyelectrolyte along with poly(sodium-4-styrene sulfonate) as an anionic polyelectrolyte for the first time on a textile substrate using this technique. The nanocoated surface was evaluated for surface characteristics such as the contact angle and scanning electron microscopy. The effect of ultrasonication during the intermediate washing steps was explored. Ultrasonication during the washing steps clearly helped in depositing more uniform bilayers onto individual fiber surfaces; this contrasted with the deposition of a continuous coating layer, which was nonuniform and had a lot of surface cracks. The use of this novel method for depositing chitosan onto cotton imparted antimicrobial properties to the fabric without adversely affecting its flexibility, feel, or breathability. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
    This paper describes electrode design, velocity and interpolar resistance measurements in a physical model of advanced Hall-Heroult cells that use inert anodes and aluminum wcttable cathodes. The principal experimental tool has been a... more
    This paper describes electrode design, velocity and interpolar resistance measurements in a physical model of advanced Hall-Heroult cells that use inert anodes and aluminum wcttable cathodes. The principal experimental tool has been a “water” model wherein gas generation was simulated by forcing compressed air through porous graphite and the fine bubbles characteristic of inert anodes were produced by adding butanol
    Platforms that feature user-generated content (social media, online forums, newspaper comment sections etc.) have to detect and filter offensive speech within large, fast-changing datasets. While many automatic methods have been proposed... more
    Platforms that feature user-generated content (social media, online forums, newspaper comment sections etc.) have to detect and filter offensive speech within large, fast-changing datasets. While many automatic methods have been proposed and achieve good accuracies, most of these focus on the English language, and are hard to apply directly to languages in which few labeled datasets exist. Recent work has therefore investigated the use of cross-lingual transfer learning to solve this problem, training a model in a well-resourced language and transferring to a less-resourced target language; but performance has so far been significantly less impressive. In this paper, we investigate the reasons for this performance drop, via a systematic comparison of pre-trained models and intermediate training regimes on five different languages. We show that using a better pre-trained language model results in a large gain in overall performance and in zero-shot transfer, and that intermediate tra...
    Background: The thyroid dysfunction particularly, subclinical hypothyroidism (SCH) is quite a common clinical condition in paediatric population but there is limited data available regarding its prevalence in children and adolescents in... more
    Background: The thyroid dysfunction particularly, subclinical hypothyroidism (SCH) is quite a common clinical condition in paediatric population but there is limited data available regarding its prevalence in children and adolescents in our population. The present study was aimed to know the prevalence of thyroid dysfunction particularly SCH in children and adolescents of northern Andhra Pradesh population and its association with hyperlipidemia.Methods: A retrospective study of 600 subjects (Children=272, Adolescents=328) between 6-19 years of age were included and the following parameters were examined: age, sex, total triiodothyronine (tT3), total tetraiodothyronine (tT4), thyroid stimulating hormone (TSH), total cholesterol, triglycerides (TGL), LDL and HDL cholesterol. The subjects were divided into group I and group II on the basis of age (in years), subjects between 6- ≤12 years age were grouped as group I and 12-≤19 years were as group II.Results: Out of 272 children and 328...
    The correlation between increased Sahel rainfall and reduced Saharan surface pressure is well established in observations and global climate models and has been used to imply that increased Sahel rainfall is caused by a stronger shallow... more
    The correlation between increased Sahel rainfall and reduced Saharan surface pressure is well established in observations and global climate models and has been used to imply that increased Sahel rainfall is caused by a stronger shallow meridional circulation (SMC) over the Sahara. This study uses two atmospheric reanalyses to examine interannual variability of Sahel rainfall and the Saharan SMC, which consists of northward near-surface flow across the Sahel into the Sahara and southward flow near 700 hPa out of the Sahara. During wet Sahel years, the Saharan SMC shifts poleward, producing a drop in low-level geopotential and surface pressure over the Sahara. Statistically removing the effect of the poleward shift from the low-level geopotential eliminates significant correlations between this geopotential and Sahel precipitation. As the Saharan SMC shifts poleward, its midtropospheric divergent outflow decreases, indicating a weakening of its overturning mass flux. The poleward shi...
    Background: Hospitalization for Heart Failure (HF) is increasing in India. Diabetes Mellitus (DM) is closely related to HF. Hb1Ac is an index of metabolic control of DM. Hb1Ac is associated with increased risk of Acute Decompensated Heart... more
    Background: Hospitalization for Heart Failure (HF) is increasing in India. Diabetes Mellitus (DM) is closely related to HF. Hb1Ac is an index of metabolic control of DM. Hb1Ac is associated with increased risk of Acute Decompensated Heart Failure (ADHF). The relation between Hb1Ac and ADHF is less well defined.Aims and Objectives: The aim of the study was to find out the prevalence of ADHF among patients admitted for cardiac complaints and to investigate Hb1Ac levels in confirmed patients.Materials and Methods: A hospital based study was conducted at NRI Heart Centre, NRI General Hospital, Guntur from May to July 2013 after institutional ethical approval. All patients of ADHF were included in the study. Patients were analysed for HbA1c.Results: Out of 1147 patients admitted in Coronary Care Unit, there were 101 cases of ADHF giving a prevalence of 8.8%. The mean age was found to be 54.69 years. 19.8% of the patients were of age less than 40. There were 74.3% males and 25.7% females....
    Carbonate reservoirs pose significant challenges for reservoir simulation and flow prediction due to lateral and vertical heterogeneities that are difficult to predict. Limits to seismic resolution, heterogeneities in rock properties and... more
    Carbonate reservoirs pose significant challenges for reservoir simulation and flow prediction due to lateral and vertical heterogeneities that are difficult to predict. Limits to seismic resolution, heterogeneities in rock properties and limited constraints on subsurface data require the consideration of multiple geologic scenarios for flow predictions. Hence, a systematic and streamlined approach is needed to construct geologic models and to quickly evaluate key sensitivities in the flow models. This paper discusses results from a reservoir analogue study in a Mesozoic carbonate ramp in the High Atlas of Morocco. Here, geologic models have been constructed from the integration of sedimentological, diagenetic and structural studies in the area. Novel methods have been applied to develop a consistent approach for rock property definitions in outcrops and incorporate multi-scale fractures to test the response in flow simulations. In these simulations we have tested the response of presence or absence of specific geologic features, including hardgrounds, stylolites and fracture populations as a way to guide the level of detail that is suitable for modeling objectives. Based on these studies, we have been able to evaluate the relative impacts of some of the geologic features on flow behavior and gain further insights to effective recovery strategies.
    Two theoretical frameworks have been widely used to understand the response of monsoons to local and remote forcings: the vertically integrated atmospheric energy budget and convective quasi-equilibrium (CQE). Existing forms of these... more
    Two theoretical frameworks have been widely used to understand the response of monsoons to local and remote forcings: the vertically integrated atmospheric energy budget and convective quasi-equilibrium (CQE). Existing forms of these frameworks neglect some of the complexities of monsoons, such as the shallow meridional circulations that advect dry air from adjacent deserts into the middle and lower troposphere of monsoon regions. Here the fidelity of energy budget and CQE theories for monsoon location is assessed in a three-dimensional beta-plane model with boundary conditions representative of an off-equatorial continent with a tropical grassland and an adjacent subtropical desert. Energy budget theories show mixed success for various SST and land surface albedo forcings, with the ITCZ being collocated with the energy flux equator but a nonmonotonic relationship existing between ITCZ latitude and cross-equatorial energy transport. Accounting for the off-equatorial position of the ...
    Time-lapse seismic monitoring of CO 2 injection into a hydrocarbon reservoir can be important for either enhanced recovery or CO 2 sequestration tasks. In the latter case, over long time periods, the interaction of CO 2 with in-situ brine... more
    Time-lapse seismic monitoring of CO 2 injection into a hydrocarbon reservoir can be important for either enhanced recovery or CO 2 sequestration tasks. In the latter case, over long time periods, the interaction of CO 2 with in-situ brine and host rock minerals ...
    Different fluids can have distinctly different effects on seismic wavefields reflected from fractured formations, and distinguishing the fluids within reservoirs using seismics is an important problem. Several theoretical results have... more
    Different fluids can have distinctly different effects on seismic wavefields reflected from fractured formations, and distinguishing the fluids within reservoirs using seismics is an important problem. Several theoretical results have been published to attempt to predict ...
    Knowledge of the orientation and spatial distribution of fractures in rocks is important for predicting the flow of fluids. Masihi et al.(2007) developed a new method of modeling these distributions beginning with theoretical results from... more
    Knowledge of the orientation and spatial distribution of fractures in rocks is important for predicting the flow of fluids. Masihi et al.(2007) developed a new method of modeling these distributions beginning with theoretical results from the physics of fracturing. We ...
    Abstract A novel spike-based computation architecture has been developed which represents synaptic weights in time. An analog chip with 32 neurons, 1024 synapses and an AER block has been fabricated in 0.5µm technology. A digital... more
    Abstract A novel spike-based computation architecture has been developed which represents synaptic weights in time. An analog chip with 32 neurons, 1024 synapses and an AER block has been fabricated in 0.5µm technology. A digital implementation of the ...
    This dissertation describes a search for the Standard Model Higgs boson produced in association with the Z boson via Higgs-strahlung at the CDF II detector at the Tevatron. At a Higgs boson mass between 100 GeV/c{sup 2} and 135 GeV/c{sup... more
    This dissertation describes a search for the Standard Model Higgs boson produced in association with the Z boson via Higgs-strahlung at the CDF II detector at the Tevatron. At a Higgs boson mass between 100 GeV/c{sup 2} and 135 GeV/c{sup 2}, the primary Higgs decay mode is ...
    Carbonate reservoirs contain a significant portion of the world’s proven hydrocarbon reserves but are challenging to produce due to their complex lithologies, structural heterogeneities, and neutral to oil-wet nature. Increasing recovery... more
    Carbonate reservoirs contain a significant portion of the world’s proven hydrocarbon reserves but are challenging to produce due to their complex lithologies, structural heterogeneities, and neutral to oil-wet nature. Increasing recovery requires a better understanding of how different recovery processes respond to the heterogeneities inherent to these reservoirs. This will contribute to the design of appropriate engineering solutions which extend the life of mature fields and develop green fields more effectively. We use a high-resolution 3D outcrop model of a Jurassic carbonate ramp in order to perform a series of detailed and systematic flow simulations. The aim is to test the impact of small- and large-scale geological features on reservoir performance and oil recovery. The outcrop analogue model is of excellent quality comprising a wide range of diagenetic and structural features, including discontinuity surfaces, mud mounds, mollusc banks and fractures. Flow simulations are pe...

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