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Article
Delta-radiomics features for predicting the major pathological response to neoadjuvant chemoimmunotherapy in non-small cell lung cancer
To investigate if delta-radiomics features have the potential to predict the major pathological response (MPR) to neoadjuvant chemoimmunotherapy in non-small cell lung cancer (NSCLC) patients.
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Article
Open AccessPyrethroid resistance status and co-occurrence of V1016G, F1534C and S989P mutations in the Aedes aegypti population from two dengue outbreak counties along the China-Myanmar border
Over the past two decades, dengue fever (DF) has emerged as a significant arboviral disease in Yunnan province, China, particularly in the China-Myanmar border area. Aedes aegypti, an invasive mosquito species, p...
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Article
Open AccessUtility and predictive value of the CRAFITY score in advanced hepatocellular carcinoma treated with transarterial chemoembolization plus tyrosine kinase inhibitors and PD-1 inhibitor
The prognostic significance of the CRAFITY score (CRP and AFP in ImmunoTherapY) has been demonstrated in hepatocellular carcinoma (HCC) patients receiving immunotherapy. The purpose of this study was to investiga...
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Article
Open AccessKoningipyridines A and B, two nitrogen-containing polyketides from the fungus Trichoderma koningiopsis SC-5
Two novel koninginin derivatives, koningipyridines A and B (1 and 2), along with four known compounds (3˗6) were isolated from the EtOAc extract of the endophytic fungus Trichoderma koningiopsis SC-5. Among them,...
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Article
Open AccessSuppression strategy for the inrush current of a solid-state transformer caused by the reclosing process
The automatic reclosing strategy is an effective measure to improve the reliability of a distribution network. It can quickly clear instantaneous faults in the grid. The traditional transformer has proven to b...
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Article
The construction efficiency study of China National Ecological Civilization Pilot Zone with network SBM model: a city-based analysis
The Chinese government proposed the establishment of China National Ecological Civilization Pilot Zone in 2016 to further explore the coordinated development of economy and environment. Fujian, Jiangxi, and Gu...
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Article
Simulation of COVID-19 symptoms in a genetically engineered mouse model: implications for the long haulers
The ongoing pandemic (also known as coronavirus disease-19; COVID-19) by a constantly emerging viral agent commonly referred as the severe acute respiratory syndrome corona virus 2 or SARS-CoV-2 has revealed u...
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Article
Open AccessQuantitative inspiratory–expiratory chest CT findings in COVID-19 survivors at the 6-month follow-up
We evaluated pulmonary sequelae in COVID-19 survivors by quantitative inspiratory–expiratory chest CT (QCT) and explored abnormal pulmonary diffusion risk factors at the 6-month follow-up. This retrospective s...
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Article
Chemical vapor deposited diamond with versatile grades: from gemstone to quantum electronics
Chemical vapor deposited (CVD) diamond as a burgeoning multifunctional material with tailored quality and characteristics can be artificially synthesized and controlled for various applications. Correspondingl...
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Article
Carbon materials: The burgeoning promise in electronics
Current electronic technology based on silicon is approaching its physical and scientific limits. Carbon-based devices have numerous advantages for next generation electronics (e.g., fast speed, low power cons...
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Article
Open AccessPrenatal and postnatal diagnoses and phenotype of 8p23.3p22 duplication in one family
Distal 8p duplication is rare but clinically significant. Duplication syndrome results in variable phenotypes, such as developmental delay, intellectual disability, and malformation of the heart. We aimed to p...
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Article
Design and therapeutic application of sodium alginate-based hydrogel with biodegradability and catalytic activity
How to efficiently treat cancer in a minimally invasive manner has become one of the major focuses of recent developments in biomedicine. In this research, biodegradable sodium alginate (SA) hydrogel encapsula...
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Article
Open AccessLaser-induced graphitization of polydopamine leads to enhanced mechanical performance while preserving multifunctionality
Polydopamine (PDA) is a simple and versatile conformal coating material that has been proposed for a variety of uses; however in practice its performance is often hindered by poor mechanical properties and hig...
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Article
Fast smoothing on diamond surface by inductively coupled plasma reactive ion etching
The synergetic effects of surface smoothing exhibited during the inductively coupled plasma reactive ion etching (ICP-RIE) of free-standing polycrystalline diamonds (PCDs) were investigated. Changing the assis...
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Article
Dual-network design to enhance the properties of agar aerogel adsorbent by incorporating in situ ion cross-linked alginate
Natural and synthetic adsorbents are used to remove contaminants from polluted waters. In particular, polymer-based aerogels are promising but their adsorption capacity and dimensional stability should be impr...
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Article
Open AccessIntegration of flux measurements and pharmacological controls to optimize stable isotope-resolved metabolomics workflows and interpretation
Stable isotope-resolved metabolomics (SIRM) provides information regarding the relative activity of numerous metabolic pathways and the contribution of nutrients to specific metabolite pools; however, SIRM exp...
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Article
Surface-enhanced Raman scattering method for the identification of methicillin-resistant Staphylococcus aureus using positively charged silver nanoparticles
The article describes a SERS-based method for diagnosis of bacterial infections. Positively charged silver nanoparticles (AgNPs+) were employed for identification of methicillin-resistant Staphylococcus aureus (M...
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Article
Open AccessComparative analysis of rodent and small mammal viromes to better understand the wildlife origin of emerging infectious diseases
Rodents represent around 43% of all mammalian species, are widely distributed, and are the natural reservoirs of a diverse group of zoonotic viruses, including hantaviruses, Lassa viruses, and tick-borne encep...
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Article
Open AccessExperimental evidence and isotopomer analysis of mixotrophic glucose metabolism in the marine diatom Phaeodactylum tricornutum
Heterotrophic fermentation using simple sugars such as glucose is an established and cost-effective method for synthesizing bioproducts from bacteria, yeast and algae. Organisms incapable of metabolizing gluco...