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Promoting international
collaboration in wheat
Matthew Reynolds
CIMMYT
GPC Symposium
Virtual, June 8th 2021
Outline
• Background –need for international collaboration-
• International Wheat Improvement Network
• International Wheat Yield Partnership
• The Wheat Initiative
• Heat & Drought Wheat Improvement Consortium
• Lessons learned
Global yield projections until 2050
Ray DK, Mueller ND, West PC, Foley JA (2013) Yield Trends Are Insufficient to Double Global Crop
Production by 2050. PLoS ONE 8(6): e66428. doi:10.1371/journal.pone.0066428
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0066428
---2.4% growth required to double production by 2050
Linear growth starting 1970
60% increase
Challenges to global crop production
• Climate unpredictable,
warmer, drier, etc.
• Depleting water resources
• Emerging diseases and
pests and their new biotypes
• Energy and fertilizer costs
• Declining agricultural
research capacity in LDCs
• Soil degradation and
erosion…..
Photo: Jalal Kamali,
14 April16. Dezful,
Khuzestan province, Iran
• 30% of the world’s arable land lost to
erosion or pollution in the last 40
years.
• Erosion rates from ploughed fields
averages 10-100 times greater than
rates of soil formation.
• It takes about 500 years to form 2.5cm
of topsoil under normal agricultural
conditions.
University of Sheffield’s Grantham Centre for Sustainable Futures, 2016
Soil loss: an unfolding global disaster
• Today more people are hungry than entire population of
South Asia at beginning of Green Revolution (1970)
• No. people living on <$2 /day same as in 1981 (~0.7 billion)
• 180 million children <5 years malnourished – in Africa 40%
of all children <5
Statistics on hunger
Source: Hans Braun/World Bank
Impact of a 1% GDP growth from agriculture and non-
agriculture on overall expenditures of the poor
0
1
2
3
4
5
6
7
Poorest 10% Poorest 11-20 Poorest 21-30%
1 % GDP growth from Agriculture
1% GDP growth from non-Agriculture
Source: Ligon and Sadoulet, 2007 in
Worldbank 2008 : World Development Report
Wheat Improvement
Importance of wheat as calorie source (2010-12)
Source: FAO-Stats, 2015
20% of all calories in
human diet globally
Most widely grown
crop globally
International Wheat Improvement Network (IWIN)
Coordinated by CIMMYT since 1960s
Source: Kai Sonder & Hans Braun
• IWIN germplasm increased productivity for >100m farmers in LDCs
(Lipton, Longhurst 1989; Evenson, Gollin 2003; Pingali et al., 2012)
• MVs saved >20 m ha land from cultivation (Stevenson et al., 2013)
• IWIN-related varieties cover over half wheat area in LDCs, giving
additional value of US $2.2-$3.1 billion p.a. spread among both
resource poor farmers and consumers (Lantican et al., 2016)
• The benefit-cost ratio of this investment is over 100:1
(without considering avoidance of devastating disease pandemics)
• IWIN has also amassed a database of over 11 million data points
IWIN cost benefit
-
10
20
30
40
50
60
70
80
90
100
China EU + other
high income
countries
ex-USSR Latin
America
S-Asia Sub-Saharan
Africa
W-Asia and
N-Africa
World
Percentage
of
releases
(%)
Unknown Variety
Non-CGIAR
parents
CGIAR Ancestry
CGIAR Parent
CGIAR Line
Spring bread wheat releases by region and origin 1994-2014
Yield
Heat
Drought
Yellow & Leaf Rust
Fusarium
Septoria
Spot blotch
Karnal Bunt
Multiple Disease Resistance
Fusarium, Septoria, Leaf Rust
Septoria
(T.durum)
Heat
Ug99
Green= Operational
Red= Planned
Phenotyping Platforms
• Hubs for generating high quality phenotypic data, under defined good practices, and
promoting training and sharing of the generated knowledge.
• Some sites represent future climate analogues, others are hotspots for specific diseases.
Rust
Septoria
Winter Wheat
Heat Drought
Yellow rust (Izmir)
Wheat blast
Yield (IN+PK)
Heat Dry (IN)
Heat Humid+
Wheat Blast (BD)
Drought (IN)
Heat
Drought
H-Fly
LR-DW
Yield
Fusarium
Yield
Yield
Global phenotyping network for wheat improvement
www.iwyp.org
A Model for Using Collaborative
International Research and
Development to Address
Important Global Problems
International Wheat Yield Partnership
www.iwyp.org
The Problem – Urgent Need to Increase Wheat
Yields to Feed 9+ Billion People by 2050
Will require a
60+ % increase
in wheat
production to
meet food
demands by
2050
www.iwyp.org
 By deploying a new model for funding and conducting a
coordinated international research program
 By combining the best ideas internationally
 By making scientific breakthroughs
 By being focused on delivery
Discoveries Delivery Development Impact
Increase the genetic yield potential of wheat
by 50% by 2035
IWYP Goal and Strategy
www.iwyp.org
Harvest Index
Biomass
Photosynthesis
IWYP
Hub(s)
Traited Germplasm
Markers
Tools
Methods
Delivery
Elite Lines
(via IWIN, others)
Phenology
Spikelet
Fertility
Sorting and Assembling the
Trait / Marker / Tool Outputs
Technology
Architecture
Makers/QTL
for yield
components
Energy Use
Efficiency
Grain size
www.iwyp.org
IWYP HUB – Validation and Development
HUB Platform approach for
Translation
 Brings all discoveries into a single central
source to compare and combine to seek
synergies and generate added value
Trait validation
Precision phenotyping
Field evaluation
Prebreeding
Trials and distribution (via IWIN, directly)
www.iwyp.org
Testing sites for progeny of physiological trait (PT)
based crosses (~ 50 sites)
Pre-breeding nurseries distributed via IWIN
• WYCYT: Wheat Yield Collaboration Yield Trial
Reynolds M.P., Pask A.J.D., Hoppitt W.J.E., Sonder K., Sukumaran S., Molero G., Saint Pierre C., Payne T., Singh R.P.,
Braun H.J., Gonzalez F.G., Terrile I.I, Barma N.C.D, Hakim A., He Z., Fan Z., Novoselovic D., Maghraby M., Gad
K.I.M., Galal E.G., Hagras A., Mohamed M.M., Morad A.F.A., Kumar U., Singh G.P., Naik R., Kalappanavar I.K.,
Biradar S., Sai Prasad S.V., Chatrath R., Sharma I., Panchabhai K., Sohu V.S., Mavi G.S., Mishra V.K., Balasubramaniam
A., Jalal-Kamali M.R., Khodarahmi M., Dastfal M., Tabib-Ghaffari S.M., Jafarby J., Nikzad A.R., Moghaddam H.A.,
Ghojogh H., Mehraban A., Solís-Moya E., Camacho-Casas M.A., Figueroa-López P., Ireta-Moreno J., Alvarado-Padilla
J.I., Borbón-Gracia A., Torres A., Quiche Y.N., Upadhyay S.R., Pandey D., Imtiaz M., Rehman M.U., Hussain M.,
Hussain M., Ud-Din R., Qamar M., Kundi M., Mujahid M.Y., Ahmad G., Khan A.J., Sial M.A., Mustatea P., von Well E.,
Ncala M., de Groot S., Hussein A.H.A., Tahir I.S.A., Idris A.A.M., Elamein H.M.M., Manes Y., Joshi A.K., 2017.
Strategic crossing of biomass and harvest index—source and sink—
achieves genetic gains in wheat. Euphytica 213:257-80
www.iwyp.org
Funding Metrics to Date – Target US$100M
www.iwyp.org
IWYPResearchandFundingPartners(14)
www.iwyp.org
IWYP Private Partners (9)
Endorsed by G20 Agriculture Ministries in 2011, WI provides framework for
strategic research priorities encompassing developed and developing countries.
Expert Working Groups:
• Adaptation to wheat abiotic stress (included HeDWIC)
• Control of wheat pathogens and pests
• Durum wheat genomics and breeding
• Global wheat germplasm conservation and use community
• Improving wheat quality for processing and health
• Nutrient use efficiency in wheat
• Wheat Agronomy
• Wheat breeding methods and strategies
• Wheat information systems
• Wheat phenotyping to support wheat improvement
• Wheat Plant and Crop Modelling
Heat and Drought Wheat
Improvement Consortium
Prioritized by WI-ICC (Jan 2016)
Source: Nature Climate Change, 1793: (13 Jan) 2013
+ 60C
+ 4.0C
+ 2.0C
Change in spring wheat productivity by 2100 in 5 scenarios
varying from 2C to 6C global average temperature increase
Response of farm yield to minimum temp
NW Mexico
HeDWIC Development
Broad consultation (370 people, 77 institutes, 32 countries):
 Determine most promising/necessary research areas
 Arrange traits/gene research into a rational framework
 Develop an organizational structure that facilitates
translational research to breeding
 Develop a bioinformatics cyber-infrastructure to support
research and delivery
Priority of heat & drought
• Poll conducted on relative priorities for EWG AWAS
• Heat and drought stress, i.e. HeDWIC clearly the top priority
Harnessing translational research
for climate resilience of wheat
Heat and Drought Wheat Improvement Consortium (HeDWIC)
HeDWIC international collaboration
including SATYN nursery sites
• Catalyzing new research
opportunities
• Disseminating new research
and breeding technologies
• Leverage of institutional
capital
• Translating research outputs
of HeDWIC/AHEAD
communities into breeding
tools through translational
research
Added value of HeDWIC and the
AHEAD umbrella for heat and drought:
AHEAD
Coordination Office
@Wheat Initiative
Initiative A HeDWIC Project N
AHEAD
Steering Committee
Annual Meetings / Data
Sharing / Seed Funding /
Project Development
Setting up international collaborations
• Clear new focus and targets
• Pre-existing informal network
• Survey literature & current research portfolios
• Develop a proposal but don’t overly prescribe
• ‘Theory of change’
• ‘Business case’
• Be prepared for a lot of leg work
• Expect grey hairs!

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Heat and Drought Wheat Improvement Consortium (HeDWIC)

  • 1. Promoting international collaboration in wheat Matthew Reynolds CIMMYT GPC Symposium Virtual, June 8th 2021
  • 2. Outline • Background –need for international collaboration- • International Wheat Improvement Network • International Wheat Yield Partnership • The Wheat Initiative • Heat & Drought Wheat Improvement Consortium • Lessons learned
  • 3. Global yield projections until 2050 Ray DK, Mueller ND, West PC, Foley JA (2013) Yield Trends Are Insufficient to Double Global Crop Production by 2050. PLoS ONE 8(6): e66428. doi:10.1371/journal.pone.0066428 http://www.plosone.org/article/info:doi/10.1371/journal.pone.0066428 ---2.4% growth required to double production by 2050 Linear growth starting 1970 60% increase
  • 4. Challenges to global crop production • Climate unpredictable, warmer, drier, etc. • Depleting water resources • Emerging diseases and pests and their new biotypes • Energy and fertilizer costs • Declining agricultural research capacity in LDCs • Soil degradation and erosion….. Photo: Jalal Kamali, 14 April16. Dezful, Khuzestan province, Iran
  • 5. • 30% of the world’s arable land lost to erosion or pollution in the last 40 years. • Erosion rates from ploughed fields averages 10-100 times greater than rates of soil formation. • It takes about 500 years to form 2.5cm of topsoil under normal agricultural conditions. University of Sheffield’s Grantham Centre for Sustainable Futures, 2016 Soil loss: an unfolding global disaster
  • 6. • Today more people are hungry than entire population of South Asia at beginning of Green Revolution (1970) • No. people living on <$2 /day same as in 1981 (~0.7 billion) • 180 million children <5 years malnourished – in Africa 40% of all children <5 Statistics on hunger Source: Hans Braun/World Bank
  • 7. Impact of a 1% GDP growth from agriculture and non- agriculture on overall expenditures of the poor 0 1 2 3 4 5 6 7 Poorest 10% Poorest 11-20 Poorest 21-30% 1 % GDP growth from Agriculture 1% GDP growth from non-Agriculture Source: Ligon and Sadoulet, 2007 in Worldbank 2008 : World Development Report
  • 9. Importance of wheat as calorie source (2010-12) Source: FAO-Stats, 2015 20% of all calories in human diet globally Most widely grown crop globally
  • 10. International Wheat Improvement Network (IWIN) Coordinated by CIMMYT since 1960s Source: Kai Sonder & Hans Braun
  • 11. • IWIN germplasm increased productivity for >100m farmers in LDCs (Lipton, Longhurst 1989; Evenson, Gollin 2003; Pingali et al., 2012) • MVs saved >20 m ha land from cultivation (Stevenson et al., 2013) • IWIN-related varieties cover over half wheat area in LDCs, giving additional value of US $2.2-$3.1 billion p.a. spread among both resource poor farmers and consumers (Lantican et al., 2016) • The benefit-cost ratio of this investment is over 100:1 (without considering avoidance of devastating disease pandemics) • IWIN has also amassed a database of over 11 million data points IWIN cost benefit
  • 12. - 10 20 30 40 50 60 70 80 90 100 China EU + other high income countries ex-USSR Latin America S-Asia Sub-Saharan Africa W-Asia and N-Africa World Percentage of releases (%) Unknown Variety Non-CGIAR parents CGIAR Ancestry CGIAR Parent CGIAR Line Spring bread wheat releases by region and origin 1994-2014
  • 13. Yield Heat Drought Yellow & Leaf Rust Fusarium Septoria Spot blotch Karnal Bunt Multiple Disease Resistance Fusarium, Septoria, Leaf Rust Septoria (T.durum) Heat Ug99 Green= Operational Red= Planned Phenotyping Platforms • Hubs for generating high quality phenotypic data, under defined good practices, and promoting training and sharing of the generated knowledge. • Some sites represent future climate analogues, others are hotspots for specific diseases. Rust Septoria Winter Wheat Heat Drought Yellow rust (Izmir) Wheat blast Yield (IN+PK) Heat Dry (IN) Heat Humid+ Wheat Blast (BD) Drought (IN) Heat Drought H-Fly LR-DW Yield Fusarium Yield Yield Global phenotyping network for wheat improvement
  • 14. www.iwyp.org A Model for Using Collaborative International Research and Development to Address Important Global Problems International Wheat Yield Partnership
  • 15. www.iwyp.org The Problem – Urgent Need to Increase Wheat Yields to Feed 9+ Billion People by 2050 Will require a 60+ % increase in wheat production to meet food demands by 2050
  • 16. www.iwyp.org  By deploying a new model for funding and conducting a coordinated international research program  By combining the best ideas internationally  By making scientific breakthroughs  By being focused on delivery Discoveries Delivery Development Impact Increase the genetic yield potential of wheat by 50% by 2035 IWYP Goal and Strategy
  • 17. www.iwyp.org Harvest Index Biomass Photosynthesis IWYP Hub(s) Traited Germplasm Markers Tools Methods Delivery Elite Lines (via IWIN, others) Phenology Spikelet Fertility Sorting and Assembling the Trait / Marker / Tool Outputs Technology Architecture Makers/QTL for yield components Energy Use Efficiency Grain size
  • 18. www.iwyp.org IWYP HUB – Validation and Development HUB Platform approach for Translation  Brings all discoveries into a single central source to compare and combine to seek synergies and generate added value Trait validation Precision phenotyping Field evaluation Prebreeding Trials and distribution (via IWIN, directly)
  • 19. www.iwyp.org Testing sites for progeny of physiological trait (PT) based crosses (~ 50 sites) Pre-breeding nurseries distributed via IWIN • WYCYT: Wheat Yield Collaboration Yield Trial Reynolds M.P., Pask A.J.D., Hoppitt W.J.E., Sonder K., Sukumaran S., Molero G., Saint Pierre C., Payne T., Singh R.P., Braun H.J., Gonzalez F.G., Terrile I.I, Barma N.C.D, Hakim A., He Z., Fan Z., Novoselovic D., Maghraby M., Gad K.I.M., Galal E.G., Hagras A., Mohamed M.M., Morad A.F.A., Kumar U., Singh G.P., Naik R., Kalappanavar I.K., Biradar S., Sai Prasad S.V., Chatrath R., Sharma I., Panchabhai K., Sohu V.S., Mavi G.S., Mishra V.K., Balasubramaniam A., Jalal-Kamali M.R., Khodarahmi M., Dastfal M., Tabib-Ghaffari S.M., Jafarby J., Nikzad A.R., Moghaddam H.A., Ghojogh H., Mehraban A., Solís-Moya E., Camacho-Casas M.A., Figueroa-López P., Ireta-Moreno J., Alvarado-Padilla J.I., Borbón-Gracia A., Torres A., Quiche Y.N., Upadhyay S.R., Pandey D., Imtiaz M., Rehman M.U., Hussain M., Hussain M., Ud-Din R., Qamar M., Kundi M., Mujahid M.Y., Ahmad G., Khan A.J., Sial M.A., Mustatea P., von Well E., Ncala M., de Groot S., Hussein A.H.A., Tahir I.S.A., Idris A.A.M., Elamein H.M.M., Manes Y., Joshi A.K., 2017. Strategic crossing of biomass and harvest index—source and sink— achieves genetic gains in wheat. Euphytica 213:257-80
  • 20. www.iwyp.org Funding Metrics to Date – Target US$100M
  • 23. Endorsed by G20 Agriculture Ministries in 2011, WI provides framework for strategic research priorities encompassing developed and developing countries. Expert Working Groups: • Adaptation to wheat abiotic stress (included HeDWIC) • Control of wheat pathogens and pests • Durum wheat genomics and breeding • Global wheat germplasm conservation and use community • Improving wheat quality for processing and health • Nutrient use efficiency in wheat • Wheat Agronomy • Wheat breeding methods and strategies • Wheat information systems • Wheat phenotyping to support wheat improvement • Wheat Plant and Crop Modelling
  • 24. Heat and Drought Wheat Improvement Consortium Prioritized by WI-ICC (Jan 2016)
  • 25. Source: Nature Climate Change, 1793: (13 Jan) 2013 + 60C + 4.0C + 2.0C Change in spring wheat productivity by 2100 in 5 scenarios varying from 2C to 6C global average temperature increase
  • 26. Response of farm yield to minimum temp NW Mexico
  • 27. HeDWIC Development Broad consultation (370 people, 77 institutes, 32 countries):  Determine most promising/necessary research areas  Arrange traits/gene research into a rational framework  Develop an organizational structure that facilitates translational research to breeding  Develop a bioinformatics cyber-infrastructure to support research and delivery
  • 28. Priority of heat & drought • Poll conducted on relative priorities for EWG AWAS • Heat and drought stress, i.e. HeDWIC clearly the top priority
  • 29. Harnessing translational research for climate resilience of wheat
  • 32. • Catalyzing new research opportunities • Disseminating new research and breeding technologies • Leverage of institutional capital • Translating research outputs of HeDWIC/AHEAD communities into breeding tools through translational research Added value of HeDWIC and the AHEAD umbrella for heat and drought: AHEAD Coordination Office @Wheat Initiative Initiative A HeDWIC Project N AHEAD Steering Committee Annual Meetings / Data Sharing / Seed Funding / Project Development
  • 33. Setting up international collaborations • Clear new focus and targets • Pre-existing informal network • Survey literature & current research portfolios • Develop a proposal but don’t overly prescribe • ‘Theory of change’ • ‘Business case’ • Be prepared for a lot of leg work • Expect grey hairs!