- Chandigarh, Chandigarh, India
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ABSTRACT Treatment failure is a major cause of concern for the Helicobacter pylori-related gastroduodenal diseases like gastritis, peptic ulcer, and gastric cancer. The antibacterial activity of Paederia foetida against few clinical... more
ABSTRACT Treatment failure is a major cause of concern for the Helicobacter pylori-related gastroduodenal diseases like gastritis, peptic ulcer, and gastric cancer. The antibacterial activity of Paederia foetida against few clinical isolates of H. pylori in vitro was examined. The MIC of P. foetida is µg/ml, showing its effectiveness in inhibiting H. pylori growth in vitro irrespective of the genetic makeup of the strains. This study provides novel insights into the therapeutic effect of P. foetida against H. pylori infection, suggesting its potential as an alternative therapy, and opens the way for further studies on identification of novel antimicrobial targets of P. foetida.
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Abstract Age, gender, and cross-national differences of children ages 8-through 16-years-old in India (n= 400) and the United States of America (n= 3,200) are examined on four bipolar temperament styles: extroversion-introversion,... more
Abstract Age, gender, and cross-national differences of children ages 8-through 16-years-old in India (n= 400) and the United States of America (n= 3,200) are examined on four bipolar temperament styles: extroversion-introversion, practical-imaginative, thinking-...
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ABSTRACT A new series of Benzylidine Rhodanine (b) have been synthesized by reaction of Rhodanine (a) and aromatic aldehydes which upon O-alkylation with different chloro- acetamides (c1- 4) form the final derivatives (d1- 4). The... more
ABSTRACT A new series of Benzylidine Rhodanine (b) have been synthesized by reaction of Rhodanine (a) and aromatic aldehydes which upon O-alkylation with different chloro- acetamides (c1- 4) form the final derivatives (d1- 4). The physical and spectral data of synthesized compounds are determined. The synthesized compounds have been screened for their anti-convulsant activity by MES method.
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The Coal Bed Methane (CBM), a dreadful mining hazard, became eco-friendly clean gas for the third world country when humanity is facing challenges against pollution and energy crisis. It is observed from the studies that the Korba and Ib... more
The Coal Bed Methane (CBM), a dreadful mining hazard, became eco-friendly clean gas for the third world country when humanity is facing challenges against pollution and energy crisis. It is observed from the studies that the Korba and Ib valley coals have potential for CBM exploration whereas Umaria coals have negligible potential. Though, the Sohagpur coalfields (east of Umaria coalfield) have ample scope of CBM exploration. In the absence of enough desorption data on gas content, the in situ gas content has been determined here following the theoretical interpretation of adsorption curve, taking into account of the moisture, ash, volatile matter, fixed carbon, depth of coal bed and the geothermal gradient. Data generation on gas content, gas saturation and gas sorption characteristics is vital for better definition of high quality coal prospects.
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Effective task-shifting interventions targeted at reducing the global cardiovascular disease (CVD) epidemic in low and middle-income countries (LMICs) are urgently needed. DISHA is a cluster randomised controlled trial conducted across 10... more
Effective task-shifting interventions targeted at reducing the global cardiovascular disease (CVD) epidemic in low and middle-income countries (LMICs) are urgently needed. DISHA is a cluster randomised controlled trial conducted across 10 sites (5 in phase 1 and 5 in phase 2) in India in 120 clusters. At each site, 12 clusters were randomly selected from a district. A cluster is defined as a small village with 250-300 households and well defined geographical boundaries. They were then randomly allocated to intervention and control clusters in a 1:1 allocation sequence. If any of the intervention and control clusters were <10 km apart, one was dropped and replaced with another randomly selected cluster from the same district. The study included a representative baseline cross-sectional survey, development of a structured intervention model, delivery of intervention for a minimum period of 18 months by trained frontline health workers (mainly Anganwadi workers and ASHA workers) and...
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We report on the synthesis and single crystal growth and characterization of a new class of S=1/2 linear chain Heisenberg system. The compounds are peroxychromates of sodium and potassium, K_3-xNa_xCrO_8. These compounds are based on Cr... more
We report on the synthesis and single crystal growth and characterization of a new class of S=1/2 linear chain Heisenberg system. The compounds are peroxychromates of sodium and potassium, K_3-xNa_xCrO_8. These compounds are based on Cr in its pentavalent oxidation state, with the unpaired electron in the 3d_x^2-y^2 or 3d_z^2 orbitals. Magnetic susceptibility measurements exhibit a rounded peak around 2.2K for K_2NaCrO8 and 3.8K for Na_3CrO_8. The magnetic susceptibility data will be discussed in relationship to specific heat measurements and low-field (X-band) EPR measurements. It is concluded that the peroxychromates are good model compounds for understanding the general properties of linear chain Heisenberg systems.
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We have described two novel implantation serine proteinase (ISP) genes that are expressed during the implantation period. The ISP1 gene may encode the embryo-derived enzyme strypsin, which is necessary for blastocyst hatching in vitro and... more
We have described two novel implantation serine proteinase (ISP) genes that are expressed during the implantation period. The ISP1 gene may encode the embryo-derived enzyme strypsin, which is necessary for blastocyst hatching in vitro and the initiation of invasion. The ISP2 gene, which encodes a related tryptase, is expressed in endometrial glands and is regulated by progesterone during the peri-implantation period. Based on similarities between ISP2 gene expression and that of a progesterone-regulated lumenal serine proteinase activity associated with lysis of the zona pellucida, we have suggested that the strypsin related protein, ISP2, may encode a zona lysin proteinase. Recently strypsin has also been found within uterine fluid, suggesting a second potential role in hatching. Consistently, we have discovered that ISP1 is also expressed in the uterine secretory gland at the time of hatching. In this study we demonstrate that both ISP1 and ISP2 are secreted together into the uterine lumen at peri-implantation, and that the appearance of ISP protein is regulated positively at the transcriptional level by progesterone and negatively at the posttranscriptional level by estrogen. This negative regulation by estrogen may be overridden in pregnancy as ISP protein expression is restored during oil-induced decidualization. ISP1 and ISP2 proteins are also expressed in proestrous suggesting additional roles in the endometrial cycle.
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AbstractA series of novel symmetrically (II) as well as unsymmetrically (VI) diaryl-substituted 1H-naphtho[1,2-e][1,3]oxazines are synthesized and screened for their antimicrobial and cytotoxic activities.
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The cooking and drying conditions for oilseeds preparatory to screw pressing are some of the most important factors that influence screw-press performance. Screw-press oil recovery, residual oil, pressing rate, and oil sediment content... more
The cooking and drying conditions for oilseeds preparatory to screw pressing are some of the most important factors that influence screw-press performance. Screw-press oil recovery, residual oil, pressing rate, and oil sediment content were measured for uncooked crambe seed and crambe seed cooked at 100C for 10 min, pressed at six moisture contents ranging from 9.2 to 3.6% dry basis.
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Congenital chylothorax in neonates is not rare. More than 300 papers are available including case-series and reviews (1). Unilateral chylothorax has been reported earlier with Noonan's Syndrome (2, 3). We report a case of bilateral... more
Congenital chylothorax in neonates is not rare. More than 300 papers are available including case-series and reviews (1). Unilateral chylothorax has been reported earlier with Noonan's Syndrome (2, 3). We report a case of bilateral congenital chylothorax in a ...
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ABSTRACT Molar excess volumes, V ijk E, and speeds of sound, U ijk , of o-toluidine (i) + benzene (j) + cyclohexane or n-hexane or n-heptane (k) ternary mixtures have been measured as a function of composition at 308.15 K. The observed... more
ABSTRACT Molar excess volumes, V ijk E, and speeds of sound, U ijk , of o-toluidine (i) + benzene (j) + cyclohexane or n-hexane or n-heptane (k) ternary mixtures have been measured as a function of composition at 308.15 K. The observed speed of sound data have been utilized to determine the excess isentropic compressibilities, (K S E) ijk , of the ternary (i+j+k) mixtures. The Moelywn-Huggins concept (Huggins in Polymer 12: 389–399, 1971) of connectivity between the surfaces of the binary mixture constituents has been extended to ternary mixtures (using the concept of a connectivity parameter of third degree of molecules, 3 ξ, which in turn depends on its topology) to obtain an expression that describes well the measured V ijk E and (K S E) ijk data. The observed data have also been analyzed in terms of Flory’s theory.
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... Order this document, ok. Titre du document / Document title. Distribution of primary nutrients in relation to soil characteristics in the Ghaggar river basin. Auteur(s) / Author(s). KULDEEP SINGH ; AHUJA RL ; Affiliation(s) du ou des... more
... Order this document, ok. Titre du document / Document title. Distribution of primary nutrients in relation to soil characteristics in the Ghaggar river basin. Auteur(s) / Author(s). KULDEEP SINGH ; AHUJA RL ; Affiliation(s) du ou des auteurs / Author(s) Affiliation(s). ...
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Research Interests: Rice and Resistance
Some mixed ligand complexes of Ni(II) with O-butyldithiocarbonate as a primary ligand and substituted pyridines as secondary ligands have been isolated and characterized on the basis of analytical data, molar conductance, magnetic... more
Some mixed ligand complexes of Ni(II) with O-butyldithiocarbonate as a primary ligand and substituted pyridines as secondary ligands have been isolated and characterized on the basis of analytical data, molar conductance, magnetic susceptibility, electronic and infrared spectral studies. The molar conductance studies show their non-electrolytic behavior. Magnetic and electronic spectral studies suggest octahedral stereochemistry around Ni(II) ions. Infrared spectral studies suggest bidentate chelating behavior of O-butyldithiocarbonate monoanion while other ligands show unidentate behavior in their complexes. One of the adduct bis(O-butyldithiocarbonato)bis(3,5-dimethylpyridine)nickel(II) crystallizes in the monoclinic space group P21/c with unit cell parameters. The crystal structure has been solved by direct methods and refined by full matrix least-squares procedures to a final R-value of 0.0379 for 2460 observed reflections. The Ni2+ ion is in a octahedral coordination environment formed by an N2S4 donor set, defined by two chelating dithiocarbonate anions as well as two 3,5-dimethylpyridine ligands with the Ni2+ ion located at the inversion centre. The packing of layers of molecules is stabilized by weak pi-pi and C-H---pi interactions.
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Thiorphan was administered intravenously (i.v.) at 10 mg/kg to conscious rats in two different models of hypertension to allow a comparison of pharmacokinetics. The two models were: 1) Deoxycorticosterone acetate (DOCA)-salt... more
Thiorphan was administered intravenously (i.v.) at 10 mg/kg to conscious rats in two different models of hypertension to allow a comparison of pharmacokinetics. The two models were: 1) Deoxycorticosterone acetate (DOCA)-salt uninephrectomized rats; 2) Spontaneously hypertensive rats (SHR), and their respective normotensive controls; 3) Sprague-Dawley (SD) rats; and 4) Wistar-Kyoto rats (WKY). Pharmacokinetic parameters were calculated for total and unbound thiorphan in plasma. In normotensive SD and WKY rats, the volume of distribution, clearance and plasma protein binding of thiorphan were not significantly different. Furthermore, the apparent elimination half-life was not significantly different for total or unbound thiorphan amongst all models. The volume of distribution and plasma clearance for both unbound and total thiorphan, however, were lower in DOCA-salt rats when compared to normotensive control rats by 61-66% and 46-51%, respectively. In contrast, pharmacokinetic parameters for both unbound and total thiorphan were not significantly different between SHR and WKY rats. These results indicate that reduced clearance of thiorphan in DOCA-salt rats may be due to the co-administration of DOCA-salt or altered renal function of the hypertrophic remaining kidney and not solely due to hypertension.
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ABSTRACT To date, very few reports of microRNAs (miRNAs) are there in the commercially important diploid Asiatic cotton although there are several reports of miRNAs in upland cotton. MicroRNAs are a large family of 19-26 nucleotides,... more
ABSTRACT To date, very few reports of microRNAs (miRNAs) are there in the commercially important diploid Asiatic cotton although there are several reports of miRNAs in upland cotton. MicroRNAs are a large family of 19-26 nucleotides, evolutionary conserved, non-coding RNA molecules that control gene expression by cleaving or inhibiting the translation of target gene transcripts in plants as well as animals. Despite the important functions of miRNAs related to the regulation of plant growth and development processes, little is known about the disease responsive miRNA. In the present study, a new pipeline for miRNA analysis using expressed sequence tags (ESTs) based bioinformatics approach has been presented. For this, 64,083 raw EST sequences of Gossypium arboreum were retrieved from EST database in NCBI. Assembled EST contigs database was used to BLAST against Gossypium raimondii miRNA dataset to predict the miRNA and 45 miRNAs of G. arboreum were predicted. Majority of the predicted miRNAs were of 24, 23, 22 and 26 nucleotides in length. The potential targets of these miRNAs were mRNAs encoding enzymes regulating essential plant metabolic pathways including the putative transcription factors, methyltransferases, disease resistance proteins, wound-responsive family protein, early nodulin related protein, phosphatase 2C family proteins and mostly are related to the responses to the biotic stresses and stress signaling in plants.
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In order to check the feasibility of various glasses as sealing materials, it is necessary to understand the crystallization kinetics, thermal and structural properties of glasses and their interactions with other components of SOFCs. In... more
In order to check the feasibility of various glasses as sealing materials, it is necessary to understand the crystallization kinetics, thermal and structural properties of glasses and their interactions with other components of SOFCs. In the present study, different alkaline earth silicate glasses have been studied for chemical interaction with different interconnects (Crofer 22APU, ODS and steel). These heat treated diffusion couple processes were investigated using X-ray diffraction (XRD), scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) in order to understand the mechanism of interface formations and their growth. No chromium rich zone could be seen along the interface after 750 h at 850°C heat treated diffusion couple indicating absence of any adverse reaction at the interface in these samples.
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Aprepitant (APT) is a lipophilic, poorly water soluble drug with moderate permeability characteristic. Therefore, we aimed to improve solubility as well as permeability that could possibly improve oral bioavailability of APT. For this... more
Aprepitant (APT) is a lipophilic, poorly water soluble drug with moderate permeability characteristic. Therefore, we aimed to improve solubility as well as permeability that could possibly improve oral bioavailability of APT. For this purpose, Quality by design (QbD) approach employing simplex lattice mixture design was used to prepare solid preconcentrated microemulsion (S-PCM). Further, the software generated numerically optimized S-PCM formulations were developed by utilizing desirability function. The spectral attributes (powder X-ray diffraction, ATR-FTIR, and differential scanning calorimetry) of S-PCM formulations suggested that APT was present in amorphous form. The results of droplet size (150-180nm), zeta potential (-13 to -15mV), poly dispersity index (PDI) (0.211-0.238) and emulsification time (&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;1min), of these S-PCM formulations (SP1, SP2 and SP3) suggested spherical shape morphology (Transmission electron microscopy) with thermodynamic stability. The comparison of in vitro/ex vivo behavior of S-PCM (SP1) with micronized and non-micronized formulations of APT suggested 2-fold and 5-fold enhancement in solubility and permeability, respectively. This was further evident from pharmacokinetic studies in rabbits that showed 1.5-fold enhancement in bioavailability of S-PCM with respect to micronized APT. Thus, it could be envisaged that development of S-PCM formulation of APT is the best alternative to micronization technology based APT formulations reported earlier.
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Exponential reduction in sequencing costs with advances in Next Generation Sequencing (NGS) technologies has led to rapid developments in the field of genotyping technologies. Genome complexity reduction methods such as Restriction... more
Exponential reduction in sequencing costs with advances in Next Generation Sequencing (NGS) technologies has led to rapid developments in the field of genotyping technologies. Genome complexity reduction methods such as Restriction Associated DNA sequencing (RAD-seq) and Genotyping by sequencing (GBS) has emerged as powerful genotyping platform which are capable of discovering, sequencing and genotyping not hundreds but thousands of markers across almost any genome of interest, but also number of individuals in a population in a single and simple experiment. GBS currently usage low coverage sequencing protocol backed by power of NGS for genotyping large populations and more precise association of genotype and phenotype. Few potential drawbacks of GBS are large propotion of missing data points due to low coverage of sequencing, management and analysis of large amount of sequence data. But with further increase in sequencing output, availability of more reference genomes and developme...
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A new variety of Ocimum americanum L. rich in citral, has been developed by natural selection and raised for two successive sowing seasons to examine the seasonal variations in herb yield and oil content, chemical variation and citral... more
A new variety of Ocimum americanum L. rich in citral, has been developed by natural selection and raised for two successive sowing seasons to examine the seasonal variations in herb yield and oil content, chemical variation and citral content. The new strain was selected because it was a short duration crop (100 days) for the production of a citral-rich oil.
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We will have to produce significantly more rice in less time to feed nine billion people without adversely affecting the resource base. For achieving this growth, several approaches including introgression of desirable alleles from the... more
We will have to produce significantly more rice in less time to feed nine billion people without adversely affecting the resource base. For achieving this growth, several approaches including introgression of desirable alleles from the wild species need to be followed. Around 2000 BILs (Backcross Inbred Lines) were developed from six AA genome species in background of indica cultivar and evaluated for desirable traits for three years. Based on evaluation, 350 BILs of three populations derived from O.rufipogon, O.glumaepatula and O.longistaminata were selected for mapping of yield contributing traits. Selected BILs were phenotyped for desirable traits in different environments and ANOVA indicated a significant variation. All BILs with their respective parents were sequenced following Genotype by sequencing on Illumina Hiseq2500. A total of 91.5 million reads were generated and aligned to 93-11 reference genome using BWA. SNPs were called using Samtools and GATK and those common betwe...
With rapid growth in internet traffic over last couple of years due to the usage of large number of internet applications, IP traffic classification becomes very necessary for various internet service providers to optimize their network... more
With rapid growth in internet traffic over last couple of years due to the usage of large number of internet applications, IP traffic classification becomes very necessary for various internet service providers to optimize their network performance and for governmental intelligence organizations. Today, traditional IP traffic classification techniques such as port number and payload based direct packet inspection techniques are
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Secondary trisomics and telotrisomics representing the 12 chromosomes of rice were isolated from the progenies of primary trisomics. A large population of each primary trisomic was grown. Plants showing variation in gross morphology... more
Secondary trisomics and telotrisomics representing the 12 chromosomes of rice were isolated from the progenies of primary trisomics. A large population of each primary trisomic was grown. Plants showing variation in gross morphology compared to the primary trisomics and disomic sibs were selected and analyzed cytologically at diakinesis and pachytene. Secondary trisomics for both arms of chromosomes 1, 2, 6, 7 and 11 and for one arm of chromosomes 4, 5, 8, 9 and 12 were identified. Telotrisomics for short arm of chromosomes 1, 8, 9 and 10 and for long arms of chromosomes 2, 3 and 5 were isolated. These secondary and telotrisomics were characterized morphologically and for breeding behavior. Secondary trisomics 2n + 1S.1S, 2n + 1L.1L, 2n + 2S.2S, 2n + 2L.2L, 2n + 6S.6S, 2n + 6L.6L and 2n + 7L.7L are highly sterile, and 2n + 1L.1L, 2n + 2L.2L and 2n + 7L.7L do not set any seed even upon backcrossing. Telotrisomics are fertile and vigorous. Genetic segregation of 43 marker genes was st...
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Abstract with rapid increase in internet traffic over last few years due to the use of variety of internet applications, the area of IP traffic classification becomes very significant from the point of view of various internet service... more
Abstract with rapid increase in internet traffic over last few years due to the use of variety of internet applications, the area of IP traffic classification becomes very significant from the point of view of various internet service providers and other governmental and private ...
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ABSTRACT Heat stress is one of the major abiotic stresses that reduce crop productivity. Global warming effects are expected to increase the probability and intensity of heat waves, thus exacerbating the existing conditions. In wheat,... more
ABSTRACT Heat stress is one of the major abiotic stresses that reduce crop productivity. Global warming effects are expected to increase the probability and intensity of heat waves, thus exacerbating the existing conditions. In wheat, reduction in yield in hot climates is primarily due to reductions in duration of growth and development. In addition, heat stress results in early leaf senescence and adverse physiological and biochemical changes. There is a strong need to develop crop plants, especially wheat for improved tolerance toward heat stress. This can be achieved by a thorough understanding of (i) various plant responses to high-temperature stress, (ii) by understanding mechanisms of heat stress tolerance, and (iii) by developing possible strategies for enhancing heat tolerance. Adverse affects of heat stress include decline in photosynthesis, increase in photorespiration, reduced water availability, loss of integrity and function of cell membrane, production of reactive oxygen species (ROS), and so on. In order to cope up with stress, plants employ a number of defense mechanisms, which includes overexpression of various enzymatic and nonenzymatic antioxidants to scavenge ROS, maintenance of membrane stability, production of various compatible solutes and metabolites, and induction of various signaling cascades. Understanding all these mechanisms can help us improve heat tolerance in plants using conventional and molecular breeding protocols and transgenic approaches. Heat tolerance in crop plants is reported to have been achieved by genetic engineering of expression of heat shock proteins, increasing the level of osmolytes and various cell detoxification enzymes, and altering membrane fluidity. Considerable variability in thermotolerance has been observed in wheat, especially in wild species including Aegilops speltoides. These tolerant species need to be exploited through integration of conventional and molecular breeding approaches. Armed with such wide information and techniques, it will be possible to rationally utilize these for the production of heat-tolerant genotypes with improved productivity.
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Isolated arterial thrombi complicating inflammatory bowel disease occurs rarely. We encountered a case of a 28-year-old man with Crohn disease who presented with abdominal pain and severe claudication and was found to have an isolated... more
Isolated arterial thrombi complicating inflammatory bowel disease occurs rarely. We encountered a case of a 28-year-old man with Crohn disease who presented with abdominal pain and severe claudication and was found to have an isolated aortoiliac thrombus. Bilateral aortoiliac thromboembolectomies were performed with successful restoration of femoral blood flow. Long-term anticoagulation therapy was instituted after an extensive hypercoagulable workup, which failed to reveal an etiology for the patient's coagulopathy. We present our case and perform an extensive literature review on this topic.
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ABSTRACT In this paper, we demonstrate three-dimensional (3D) object encryption using diffractive imaging and digital holography. For this purpose, a microlens array has been fabricated using the thermal reflow method, and then its... more
ABSTRACT In this paper, we demonstrate three-dimensional (3D) object encryption using diffractive imaging and digital holography. For this purpose, a microlens array has been fabricated using the thermal reflow method, and then its digital hologram is recorded. The hologram of the microlens is encoded based on multiple intensity samplings of the complex-amplitude wave front with axial translation of the image sensor in the fractional Fourier transform domain. Then, the function is Fresnel propagated for three different positions of the camera, and the corresponding diffraction patterns are recorded as cipher-texts. For decryption, an iterative phase retrieval algorithm is applied to extract the hologram from corresponding encrypted images. The corresponding phase profile of the microlens array is then obtained. The simulation results demonstrate that the hologram is decrypted without any stagnation problem and with a rapid convergence rate. High security of the hologram has been achieved in the proposed digital holography-based diffractive imaging scheme. The correlation coefficient, a performance measurement parameter, has been calculated to check the effectiveness of the scheme. The proposed work has been validated through both experimental and simulation results.
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A 6-year-old, spayed female domestic shorthair cat was referred for an intermittent cough and wheezing of 3 to 4... more
A 6-year-old, spayed female domestic shorthair cat was referred for an intermittent cough and wheezing of 3 to 4 months&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39; duration. Thoracic radiography revealed atelectasis of the right middle and caudal lung lobes with hyperinflation of the accessory lobe, consistent with bronchial obstruction. Bronchoscopy confirmed a narrowing of the right mainstem bronchial lumen; however, positive-pressure ventilation resulted in a severe pneumothorax. A lateral thoracotomy and right caudal lung lobectomy resulted in complete resolution of the pneumothorax and respiratory signs. Histopathology and culture of the lung revealed Paecilomyces lilacinus. The cat was placed on itraconazole therapy for 6 months. Since dismissal from the hospital, the cat has not exhibited clinical evidence of wheezing, coughing, or dyspnea and is neurologically normal.
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Congenital contractural arachnodactyly is a rare autosomal dominant disorder characterized by crumpled ears, con-genital contractures, arachnodactyly and scoliosis. Only few cases have been described to date. Here we report a newborn with... more
Congenital contractural arachnodactyly is a rare autosomal dominant disorder characterized by crumpled ears, con-genital contractures, arachnodactyly and scoliosis. Only few cases have been described to date. Here we report a newborn with congenital contractures, crumpled ears and scoliosis. Molecular analysis revealed a novel fibrillin-2 mutation at the donor splice site of intron 28. We discuss the differential diagnosis of neonates with congenital contractures and review the current knowledge on congenital contractural arachnodactyly.
The objective of this study was to assess the role of leukotoxin (LKT) in modulating the pulmonary cytokine response of calves challenged with Mannheimia haemolytica. Thirty-six calves, seronegative to LKT and M. haemolytica whole cell... more
The objective of this study was to assess the role of leukotoxin (LKT) in modulating the pulmonary cytokine response of calves challenged with Mannheimia haemolytica. Thirty-six calves, seronegative to LKT and M. haemolytica whole cell antigen were divided into three groups (I, II and III). Calves in groups I and II were challenged by the intra-bronchial route with 25 mL of phosphate buffered saline (PBS) containing 0.44×10(9) cfu/mL of LKT deficient (lkt(-)) and 25 mL of PBS containing 0.31×10(9) cfu/mL of wild-type (wt) M. haemolytica serotype 1, respectively. Group III calves were challenged intra-bronchially with 25 mL of sterile PBS. Leukocytes were collected from broncho-alveolar lavage fluid (BALF) 4 days before and at 1, 3, and 6 days post-inoculation (p.i.). Expression of the following cytokines in the recovered leukocytes was measured using real-time PCR: interleukin (IL)-1β, -8, -10, -12 (p40) and TNF-α. The amount of TNF-α produced was also quantified by ELISA. Although a statistically significant difference in the expression of these cytokines was not observed between groups challenged with the wt and lkt(-) strains, the wt infected group (II) did exhibit higher mean clinical scores. Overall, there was considerable variation in the composition of the BALF between the groups and by day 7 p.i., both lkt(-)- and wt-challenged calves had seroconverted to M. haemolytica.
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Leukotoxin (LKT) is a virulence factor for Mannheimia haemolytica. In this study, bovine alveolar macrophages (BAMs) were challenged with wild type (wt) and LKT deficient (lkt(-)) M. haemolytica at a concentration of 1 bacterium/BAM and... more
Leukotoxin (LKT) is a virulence factor for Mannheimia haemolytica. In this study, bovine alveolar macrophages (BAMs) were challenged with wild type (wt) and LKT deficient (lkt(-)) M. haemolytica at a concentration of 1 bacterium/BAM and the cytokine response was quantified by ELISA and real-time reverse transcriptase-PCR. Significant increases in protein concentrations of tumor necrosis factor (TNF)-α and interleukin (IL)-10 were observed in supernatants obtained from BAMs challenged with the lkt(-) strain of M. haemolytica compared with wt challenged BAMs. There were no significant differences in mRNA expression of TNFα, IL-1ß, IL-6, IL-8 or IL-10 between BAMs challenged with the lkt(-) strain of M. haemolytica compared with wt challenged BAMs. BAMs challenged with the wt strain exhibited, on average, 43% more cytotoxicity than lkt(-) challenged BAMs (P&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;0.01).
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Page 1. Sustainable Management of Natural Resources for Food Security and Environmental Quality: Case Studies from India A Review SP Palaniappan, A. Chandrasekaran, DS Kang,Kuldeep Singh, RP Rajput, DL Kauraw, M. Velayutham, and R. Lal... more
Page 1. Sustainable Management of Natural Resources for Food Security and Environmental Quality: Case Studies from India A Review SP Palaniappan, A. Chandrasekaran, DS Kang,Kuldeep Singh, RP Rajput, DL Kauraw, M. Velayutham, and R. Lal ...
Research Interests: Operations Research, Sustainable agriculture, South India, Food Security, Water Management, and 22 moreSeasonality, Maize, Case Study, Drip Irrigation, Soybean, Pest control, Integrated nutrient management on crops, Soil Fertility, Soil Conservation, Green Manure, Environmental quality, Sustainable Management, Crop Rotation, Natural Resource, Best management practice, Management Strategy, Large Scale, Glycine max, Crop Yield, Cropping System, Pigeon, and Benefit Cost Ratio
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Research Interests: QSAR and Antimicrobial
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Neonatal septicemia is the most important cause of neonatal mortality. A wide variety of bacteria both aerobic and anaerobic can cause neonatal sepsis. Genus Pantoea is a member of Enterobacteriaceae family that inhabits plants, soil and... more
Neonatal septicemia is the most important cause of neonatal mortality. A wide variety of bacteria both aerobic and anaerobic can cause neonatal sepsis. Genus Pantoea is a member of Enterobacteriaceae family that inhabits plants, soil and water and rarely causes human infections, however, Pantoea dispersa has not been reported as a causative organism for neonatal sepsis. We hereby report two neonates with early onset sepsis caused by Pantoea dispersa. Early detection and appropriate antibiotic therapy can improve overall outcome of this rare infection in neonates.
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Carotid artery stenosis and coronary artery disease share common risk factors and often coexist in the same patient. Currently, no consensus exists regarding the optimal treatment strategy for patients with concomitant severe coronary and... more
Carotid artery stenosis and coronary artery disease share common risk factors and often coexist in the same patient. Currently, no consensus exists regarding the optimal treatment strategy for patients with concomitant severe coronary and carotid disease. We reviewed the results of our experience performing off-pump coronary artery bypass grafting (CABG) within 24 hours of carotid endarterectomy (CEA) in this select patient population. In this single institution retrospective study we identified patients who underwent CEA followed by CABG from March 2001 to March 2012. Preoperative, intraoperative, and postoperative data were collected and analyzed. Ninety patients underwent CEA followed by off-pump CABG. The duration between CEA and CABG was 1.8±5.6 days with 80 (89%) within 24 hours. Mean age was 69±9 years, 68% male. Perioperative comorbidities included hypertension (87%), diabetes (50%), previous myocardial infarction (24%), peripheral arterial disease (20%), and strokes and tra...
Research Interests: Treatment Outcome, Humans, Female, Male, Follow-up studies, and 13 moreIncidence, Clinical Sciences, New York, Aged, Coronary Angiography, Time Factors, Survival Rate, Retrospective Studies, Carotid Endarterectomy, Coronary Artery Disease, Carotid Stenosis, Postoperative Complications, and Severity of Illness Index
Research Interests: Materials Engineering, Materials Chemistry, Magnetic Materials, Transmission Electron Microscopy, Conducting Polymer, and 9 moreMagnetic Properties, Dielectric Properties, X ray diffraction, Dielectric Constant, Particle Size, Fourier transform infrared spectroscopy, Electric Conductivity, Vibrating Sample Magnetometer, and Thermal gravimetric analysis
Understanding the nature of novelty is a crucial first step in managing the changes associated with any novelty. The objectives of this paper are therefore to: (1) elucidate the major changes from Web-based commerce to M-commerce using... more
Understanding the nature of novelty is a crucial first step in managing the changes associated with any novelty. The objectives of this paper are therefore to: (1) elucidate the major changes from Web-based commerce to M-commerce using the hypercube novelty model, (2) ...
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ABSTRACT So far, authors have published two articles on uranium quantification in groundwater in India. One manuscript entitled “Uranium concentration in groundwater in Hisar city, India”, published in The International Journal of... more
ABSTRACT So far, authors have published two articles on uranium quantification in groundwater in India. One manuscript entitled “Uranium concentration in groundwater in Hisar city, India”, published in The International Journal of Occupational and Environmental Medicine (IJOEM) [1]; and another entitled “Uranium in groundwater from Western Haryana, India”, published in Journal of Radioanalytical and Nuclear Chemistry [2]. Dr. Rathore has already written a Letter to the Editor of the IJOEM [1]. The appropriate responses were prepared and published in the journal [3]. Now, Dr. Rathore has given comments to the Editor of JRNC on second article, Singh et al. [2]. We believe that these comments have been prepared on the basis of three publications [1–3] although most of the comments have already been responded in the IJOEM [3], we try to make things more clear as follows.Dr. Rathore implies that the information furnished about uranium analysis instrument by Singh et al. [2] is incorrect and mislea
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Plane slow motion of an incompressible, electrically conducting and viscous fluid past a circular cylinder placed midway between the two parallel walls in a channel in the presence of a uniform magnetic field parallel to the walls is... more
Plane slow motion of an incompressible, electrically conducting and viscous fluid past a circular cylinder placed midway between the two parallel walls in a channel in the presence of a uniform magnetic field parallel to the walls is considered; the consideration is ...
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Research Interests: Materials Engineering, Mechanical Engineering, Raman Spectroscopy, Scanning Electron Microscopy, Wear, and 12 moreTribology, Adhesion, Strain Rate, Erosion, Plasma Treatment, Nitrogen, Composite Material, High Temperature, Wear resistance, Carbon Fiber, Elevated Temperature, and Solid Particle Erosion
... DOUBLE FORAMEN TRANSVERSARIUM IN CERVICAL VERTEBRA AN OSTEOLOGICAL STUDY Archana Sharma, Kuldeep Singh, Vishnu Gupta, Shubha Srivastava Department of ... was noted out of which C3 (.5%), C4 (1.5%), C5 (2%), C6 (4%). Das srijit(2005)... more
... DOUBLE FORAMEN TRANSVERSARIUM IN CERVICAL VERTEBRA AN OSTEOLOGICAL STUDY Archana Sharma, Kuldeep Singh, Vishnu Gupta, Shubha Srivastava Department of ... was noted out of which C3 (.5%), C4 (1.5%), C5 (2%), C6 (4%). Das srijit(2005) reported two ...
In search of new selective anti-cancer agents, a series of sixteen novel 2-aminoimidazole-quinoline hybrid compounds (5a-5p) have been designed and synthesized regioselectively. We have characterized the compounds extensively using IR, 1D... more
In search of new selective anti-cancer agents, a series of sixteen novel 2-aminoimidazole-quinoline hybrid compounds (5a-5p) have been designed and synthesized regioselectively. We have characterized the compounds extensively using IR, 1D and 2D NMR Spectroscopy and mass spectrometry. The cytotoxicity studies against different cancer cell lines showed that the compound 5a (Imd-Ph) emerged as a potent cytotoxic scaffold. Imd-Ph (5a) exhibited a selective anticancer activity against human colon cancer cell line (HCT-116, DLD-1) and was found relatively non-toxic to breast cancer cells (MDA-MB-231) as well as to normal primary endothelial cells (HUVEC). Structure-activity relationship of imidazole-quinoline hybrid scaffolds revealed differential and selective toxicities exerted by the different derivatives against cancer and normal cells. Structural modification of the scaffold with library of a wide variety of substituents may lead to the development of novel selective anti-cancer age...
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ABSTRACT Rice (Oryza sativa L) is an important cereal for one-third of the world’s population. Its productivity is continually threatened by a series of biotic and abiotic stresses. There is thus an urgent need to broaden the gene pool of... more
ABSTRACT Rice (Oryza sativa L) is an important cereal for one-third of the world’s population. Its productivity is continually threatened by a series of biotic and abiotic stresses. There is thus an urgent need to broaden the gene pool of rice for developing varieties with high yield and resistance to several stresses. Wild species of Oryza are a reservoir of genes for tolerance to various biotic and abiotic stresses and also possess yield-enhancing loci. Morphological, cytological, and molecular divergence studies have been used to identify ten genome types in 22 Oryza species. Interspecific hybrids and alien introgression lines have been produced. Genes for resistance to grassy stunt virus, tungro virus, brown planthopper, bacterial blight, blast, tolerance to soil toxicity, and cytoplasmic male sterility have been transferred from wild species and varieties released. Many of the genes/QTL introgressed from wild species have been tagged with DNA markers. Xa21, a gene for bacterial blight resistance has been pyramided along with other genes through MAS and 12 varieties/hybrids released. Molecular analysis has shown limited introgression of short segments from distant genomes. Parental genomes and alien chromosomes segments have been characterized using genomic in situ hybridization. BAC libraries from different wild species have been established. BAC end sequence, physical framework of different genomes of Oryza, and alignment with the rice reference genome have provided valuable information on evolutionary mechanisms and on genome organization, structural rearrangements, repeats, transposable elements, SSR, miRNA, and single nucleotide variation. Long terminal repeated (LTR)-retrotransposons are considered as the predominant class of repeat elements that increase the genome size in some species. Introgression of genes with broad spectrum of resistance to stresses, yield-enhancing loci/QTLs, and identification of genes controlling homoeologous pairing to introgress wild species genes from distant genomes need to be explored. BAC libraries and CSSL of wild relatives are important genetic resource for functional genomics and for mapping and cloning of agronomically important genes/QTLs harbored in wild species of Oryza. With the advances in tissue culture techniques, molecular markers, and genomics, the scope for utilization of wild species in genetic enhancement of rice seems more promising than before.
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This prospective, non-randomized, comparative study evaluated morbidity of chemotherapy administration via a totally implantable venous access device (TIVAD) versus peripheral intravenous access (PIVA), and satisfaction in breast cancer... more
This prospective, non-randomized, comparative study evaluated morbidity of chemotherapy administration via a totally implantable venous access device (TIVAD) versus peripheral intravenous access (PIVA), and satisfaction in breast cancer patients in a limited-resource setting. Consecutive patients receiving chemotherapy via TIVAD (n = 114) or PIVA (n = 159) were studied. Venous access-related events were recorded. Morbidity and satisfaction with TIVAD or PIVA as perceived by the patients were assessed using a specifically designed questionnaire, which patients filled after 1st cycle of, and after completion of all chemotherapy. Patients in the two groups were of comparable age, body mass index, and disease stage. Acceptance of TIVAD was higher in literate patients. TIVAD did not interfere with sleep or activities in 90 % of patients. The majority (81.2 %) were satisfied with the cosmetic outcome, 91.5 % would have TIVAD re-inserted if the need arose, and 89.6 % would recommend it to others. Non-fatal complications occurred in 16 patients, and TIVAD had to be removed prematurely in five patients. In the PIVA group, 40 % needed multiple needle pricks and 55.8 % developed thrombophlebitis or staining of arms. Drug extravasation and ulceration were suffered by 8.3 and 4.2 %, respectively. However, 78.3 % of patients reported no interference with daily activities and only 26 % would prefer a TIVAD. Those receiving more than six chemotherapy cycles were dissatisfied to a greater extent with PIVA (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05). Breast cancer chemotherapy via TIVAD is safe and convenient and results in high satisfaction levels, although it involves additional expenditure. Chemotherapy via PIVA is acceptable, albeit with lower satisfaction, more so in those receiving more than six chemotherapy cycles.
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Abstract Polyethersulfone (PES) composites were developed with carbon fabric (CF). Cold remote nitrogen oxygen plasma (CRNOP) treatment was employed to the CF to incorporate functional groups and promote fiber matrix adhesion. This study... more
Abstract Polyethersulfone (PES) composites were developed with carbon fabric (CF). Cold remote nitrogen oxygen plasma (CRNOP) treatment was employed to the CF to incorporate functional groups and promote fiber matrix adhesion. This study includes the effect of PES melt ...
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A mixed model framework was defined for QTL analysis of multiple traits across multiple environments for a RIL population in pepper. Detection power for QTLs increased considerably and detailed study of QTL by environment interactions and... more
A mixed model framework was defined for QTL analysis of multiple traits across multiple environments for a RIL population in pepper. Detection power for QTLs increased considerably and detailed study of QTL by environment interactions and pleiotropy was facilitated. For many agronomic crops, yield is measured simultaneously with other traits across multiple environments. The study of yield can benefit from joint analysis with other traits and relations between yield and other traits can be exploited to develop indirect selection strategies. We compare the performance of three multi-response QTL approaches based on mixed models: a multi-trait approach (MT), a multi-environment approach (ME), and a multi-trait multi-environment approach (MTME). The data come from a multi-environment experiment in pepper, for which 15 traits were measured in four environments. The approaches were compared in terms of number of QTLs detected for each trait, the explained variance, and the accuracy of prediction for the final QTL model. For the four environments together, the superior MTME approach delivered a total of 47 regions containing putative QTLs. Many of these QTLs were pleiotropic and showed quantitative QTL by environment interaction. MTME was superior to ME and MT in the number of QTLs, the explained variance and accuracy of predictions. The large number of model parameters in the MTME approach was challenging and we propose several guidelines to help obtain a stable final QTL model. The results confirmed the feasibility and strengths of novel mixed model QTL methodology to study the architecture of complex traits.
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This study tests the relationship between strategic HR orientation and firm performance. The study has been conducted to add to the growing empirical evidence in this field. The study has been carried out in the Indian setting, where the... more
This study tests the relationship between strategic HR orientation and firm performance. The study has been conducted to add to the growing empirical evidence in this field. The study has been carried out in the Indian setting, where the importance of human resources has ...
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Research Interests: Technology, Fungi, Innate immunity, Polyploidy, Biological Sciences, and 14 morePlant Genome Project, Plant diseases, Pollen, Bread, Genotype, Chromosome segregation, Quantitative Trait Loci, Reproducibility of Results, Bread Wheat, Triticum, Field Data, Genetic Markers, Diploidy, and Inheritance Patterns
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Abstract Water balance components under wheat were assessed by employing two simple models, differing in their structure and data requirements, namely the soil-plantatmospherewater (SPAW) model of Saxton (1989) and the water balance... more
Abstract Water balance components under wheat were assessed by employing two simple models, differing in their structure and data requirements, namely the soil-plantatmospherewater (SPAW) model of Saxton (1989) and the water balance model (WBM) of Arora et al.( ...
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An important lesion in... more
An important lesion in Alzheimer&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;s disease (AD) patient brains is the neurofibrillary tangle (NFT). Hyperphosphorylated tau is its major component. In a former paper we described some NFT in the canine brain. During aging, moreover, advanced glycation end products (AGE) might accumulate. Glycated tau induces lipid peroxidation in vivo and tau and AGE antigens have been mentioned to co-localize in NFT. This indicates that AGE may play an important role in Alzheimer disease (AD) by oxidation of tau. The aim of the present study was to investigate amyloid, neurofibrillary tangles, Abeta precursor protein, Abeta, tau, ubiquitin, advanced glycation end products, 4-hyroxynonenal protein and lipofuscin in a series of dogs of varying ages. The results showed a significant positive correlation between age and amyloid quantity (Congo red staining), HNE staining and lipofuscin (LF), and between amyloid quantity and HNE staining and LF. Staining for AbetaPP seemed to have a tendency to increase with age, whereas staining for tau, ubiquitin and AGE each only gave limited positive results in a proportion of the older dogs. Preliminary studies including loss of cognitive capabilities in the older dogs and chemical measurement of lipofuscin-like pigment (LFP) accumulation in brain extracts revealed an increase with old age and dementia. The Congo red, HNE and LF results suggest that deposition of amyloid with aging might be associated with formation of end products of lipid peroxidation. The finding of the limited positive signals for tau, ubiquitin and AGE in some old cases might indicate that the spontaneous brain pathology of the aged dog reveals similarities to early stages observed in AD in humans especially those with Down syndrome.
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The aim of the human resources function (management and development) in the organizational context is to ensure the availability of competent, motivated and learning employees to the firm to facilitate the achievement of its business... more
The aim of the human resources function (management and development) in the organizational context is to ensure the availability of competent, motivated and learning employees to the firm to facilitate the achievement of its business objectives. The HR ...
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... Please follow the link if you wish to visit the database now. Synthetic Communications. ... Superoxide Ion Induced Oxidation of γ‐Lactones to γ‐Ketocarboxylic Acids. ... DOI: 10.1081/SCC-200043177 S. Singh a , M. Verma b &amp;amp;... more
... Please follow the link if you wish to visit the database now. Synthetic Communications. ... Superoxide Ion Induced Oxidation of γ‐Lactones to γ‐Ketocarboxylic Acids. ... DOI: 10.1081/SCC-200043177 S. Singh a , M. Verma b &amp;amp; KN Singh b * pages 4471-4475. ...
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... ples. Gayatri Devi shot a panther at an early age. As she recalls: Early in the morning, the news was brought by some villagers that a panther had to be killed in a nearby area, so after lunch Indrajit, Menaka and I set off. Each ...
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... The present investigation was; therefore, undertaken to (i) study the effect of different tillage and crop residue management practices on growth, weed biomass, soil properties and yield of wheat, (ii) identify alternative tillage... more
... The present investigation was; therefore, undertaken to (i) study the effect of different tillage and crop residue management practices on growth, weed biomass, soil properties and yield of wheat, (ii) identify alternative tillage systems to conventional sowing of wheat and ...
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Rice has become a model cereal plant for molecular genetic research. Rice has the most comprehensive molecular linkage maps with more than 2000 DNA markers and shows synteny and colinearity with the maps of other cereal crops. Until now,... more
Rice has become a model cereal plant for molecular genetic research. Rice has the most comprehensive molecular linkage maps with more than 2000 DNA markers and shows synteny and colinearity with the maps of other cereal crops. Until now, however, no information was available about the positions of centromeres and arm locations of markers on the molecular linkage map. Secondary and telotrisomics were used to assign restriction fragment length polymorphism markers to specific chromosome arms and thereby to map the positions of centromeres. More than 170 restriction fragment length polymorphism markers were assigned to specific chromosome arms through gene dosage analysis using the secondary and telotrisomics and the centromere positions were mapped on all 12 linkage groups. The orientations of seven linkage groups were reversed to fit the &quot;short arm on top&quot; convention and the corrected map is presented.
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Research Interests: Engineering, Transmission Electron Microscopy, High Resolution Transmission Electron Microscopy, Magnetic Properties, Activation Energy, and 6 moreThermal Analysis, X ray diffraction, Fourier transform infrared spectroscopy, Thermogravimetric Analysis, Thermal Properties, and Vibrating Sample Magnetometer
Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining your privacy and will not share your personal information without your express consent. For more information, please refer to our... more
Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining your privacy and will not share your personal information without your express consent. For more information, please refer to our Privacy Policy. ... An abstract is unavailable. This article is ...
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ABSTRACT Karnal bunt (KB) of wheat, caused by Tilletia indica (Mitra) Mundkur, adversely affects international wheat trading and the movement of germplasm between countries due to quarantine restrictions. Breeding for host plant... more
ABSTRACT Karnal bunt (KB) of wheat, caused by Tilletia indica (Mitra) Mundkur, adversely affects international wheat trading and the movement of germplasm between countries due to quarantine restrictions. Breeding for host plant resistance requires the identification of KB resistance sources. Accessions of the D genome progenitor of bread wheat, Aegilops tauschii, were screened in a specially designed screen-house, where the optimum environmental conditions conducive for KB development were simulated by controlling temperature, humidity, fogging and shading. The 183 accessions were subjected to artificial inoculation with a mixture of nine KB isolates, and seven proved highly resistant and four moderately resistant over three rounds of screening over 3 years.
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In spite of being a common diagnosis in the patients of Asian origin, atypical presentations of tuberculosis may pose diagnostic challenges. We report a huge prevertebral abscess in a 30-year-old female, mimicking a leaking aortic... more
In spite of being a common diagnosis in the patients of Asian origin, atypical presentations of tuberculosis may pose diagnostic challenges. We report a huge prevertebral abscess in a 30-year-old female, mimicking a leaking aortic aneurysm. The patient was managed successfully by emergency decompression and stabilization. The issues related to poor patient compliance to chemotherapy and management of atypical presentations of spinal tuberculosis are discussed here.
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... Whereas PR 108, Pusa Basmati 1, super basmati and Pusa Sugandh 2 formed independent clusters, owing to their diverse nature. ... Joshi AM, Sarao NK, Sharma RC, Singh P and Bharaj TS (2007) Varietal characterization of rice (Oryza... more
... Whereas PR 108, Pusa Basmati 1, super basmati and Pusa Sugandh 2 formed independent clusters, owing to their diverse nature. ... Joshi AM, Sarao NK, Sharma RC, Singh P and Bharaj TS (2007) Varietal characterization of rice (Oryza sativa L.) based on morphological ...
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One of the most concerning and potentially fatal complications of gastric bypass surgery is pulmonary embolism (PE) with published rates exceeding 1%. Although this procedure has been proven effective in reducing the morbidity and... more
One of the most concerning and potentially fatal complications of gastric bypass surgery is pulmonary embolism (PE) with published rates exceeding 1%. Although this procedure has been proven effective in reducing the morbidity and mortality of obesity and associated health care costs, it is elective and risk must be minimized. No dosing guidelines exist for pharmacologic prophylaxis in obese patients who are already at increased risk for these events. Although the current ASMBS and Chest guidelines recommend preoperative pharmacologic prophylaxis against thromboembolic events, no standard dosing protocols exist for the obese population. We propose a protocol including immediate pre followed by twice daily postoperative BMI-based dosing of low-molecular-weight heparin (LMWH), along pneumatic compression devices, and early ambulation. We retrospectively reviewed the charts of 170 patients who underwent Roux-en-Y gastric bypass surgery between March 2004 and December 2007. The incidence of deep venous thrombosis (DVT) and PE and bleeding complications associated with a BMI-based preoperative dosing protocol of LMWH was determined. All patients received LMWH preoperatively within 1 h of the incision, with doses varying between 30 and 60 mg given subcutaneously. Eleven patients received 30 mg, 145 patients received 40 mg, 9 patients received 50 mg, and 5 patients received 60 mg. None of the patients suffered from clinically significant DVT or PE during the hospital stay or in follow up (&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;2 years). Five patients (2.9%) were treated with discontinuation of lovenox and blood transfusion for postoperative bleeding. One of those patients returned to the operating room for exploration. We propose that immediate BMI-based preoperative dosing of LMWH along with postoperative prophylaxis is both safe and effective and should be standard for all patients undergoing Roux-en-Y gastric bypass surgery.
Research Interests: Health Care, Treatment Outcome, Laparoscopic Surgery, Humans, Operating Room, and 14 moreFemale, Pulmonary Embolism, Male, cerebral Venous sinus thrombosis, Body Mass Index, Obesity Surgery, Clinical Sciences, Adult, Public health systems and services research, Retrospective Studies, Blood Transfusion, Gastric Bypass, Deep Venous Thrombosis, and Postoperative Complications
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Abstract. In a greenhouse experiment the response of chickpea (Cieer arietinum) to zinc fertilization was examined using 27 soils from the semi-arid tropics. The critical level of DTPA extractable soil Zn was evaluated. Zinc additions to... more
Abstract. In a greenhouse experiment the response of chickpea (Cieer arietinum) to zinc fertilization was examined using 27 soils from the semi-arid tropics. The critical level of DTPA extractable soil Zn was evaluated. Zinc additions to the soil increased the dry matter yield of six ...
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Research Interests: Face, India, Humans, Skull, Male, and 4 moreMucormycosis, Clinical Sciences, Middle Aged, and Blood Vessels
The aim of the present study was to find out the relationship between the human resources management practices and firm level performance. The study conducted on 82 Indian firms indicates that there is a significant relationship between... more
The aim of the present study was to find out the relationship between the human resources management practices and firm level performance. The study conducted on 82 Indian firms indicates that there is a significant relationship between the two human resources practices, namely, training ...
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We have described two novel implantation serine proteinase (ISP) genes that are expressed during the implantation period. The ISP1 gene may encode the embryo-derived enzyme strypsin, which is necessary for blastocyst hatching in vitro and... more
We have described two novel implantation serine proteinase (ISP) genes that are expressed during the implantation period. The ISP1 gene may encode the embryo-derived enzyme strypsin, which is necessary for blastocyst hatching in vitro and the initiation of invasion. The ISP2 gene, which encodes a related tryptase, is expressed in endometrial glands and is regulated by progesterone during the peri-implantation period. Based on similarities between ISP2 gene expression and that of a progesterone-regulated lumenal serine proteinase activity associated with lysis of the zona pellucida, we have suggested that the strypsin related protein, ISP2, may encode a zona lysin proteinase. Recently strypsin has also been found within uterine fluid, suggesting a second potential role in hatching. Consistently, we have discovered that ISP1 is also expressed in the uterine secretory gland at the time of hatching. In this study we demonstrate that both ISP1 and ISP2 are secreted together into the uterine lumen at peri-implantation, and that the appearance of ISP protein is regulated positively at the transcriptional level by progesterone and negatively at the posttranscriptional level by estrogen. This negative regulation by estrogen may be overridden in pregnancy as ISP protein expression is restored during oil-induced decidualization. ISP1 and ISP2 proteins are also expressed in proestrous suggesting additional roles in the endometrial cycle.
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Abstract: The present research work deals with the dielectric properties of polyaniline–nano ferrite composites prepared using chemical oxidative polymerization. The resulting composite possesses the conductivity of 2.5 S/cm and... more
Abstract: The present research work deals with the dielectric properties of polyaniline–nano ferrite composites prepared using chemical oxidative polymerization. The resulting composite possesses the conductivity of 2.5 S/cm and saturation magnetization of 45emu/g. The comparative studies of microwave absorption of ferromagnetic conducting polyaniline composite were carried out by casting in film in poly (vinyl alcohol). The effects of the weight fraction of PANI-Fe2O3 composite on the frequency dispersion characteristics of the ...
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Research Interests: Treatment Outcome, Risk assessment, Vascular Surgery, Prospective studies, Humans, and 19 moreHeparin, Female, Pulmonary Embolism, Male, Young Adult, cerebral Venous sinus thrombosis, Anticoagulants, Risk factors, Recurrence, New York, Aged, Middle Aged, Adult, Time Factors, Leg, Disease Progression, Risk Factors, Risk Assessment, and Deep Venous Thrombosis
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ABSTRACT The thermal properties of hypervalent iodine reagents (iodobenzene diacetate, bis(trifluoroacetoxy)iodobenzene, [hydroxyl(mesyloxy)]iodobenzene, [hydroxy(tosyloxy)] iodobenzene) and polymer-supported hypervalent iodine reagents... more
ABSTRACT The thermal properties of hypervalent iodine reagents (iodobenzene diacetate, bis(trifluoroacetoxy)iodobenzene, [hydroxyl(mesyloxy)]iodobenzene, [hydroxy(tosyloxy)] iodobenzene) and polymer-supported hypervalent iodine reagents (polystyrene-supported iodobenzene diacetate, polystyrene-supported bis(trifluoroacetoxy)iodobenzene, polystyrene-supported[hydroxyl(mesyloxy)]iodobenzene, polystyrene-supported [hydroxy(tosyloxy)] iodobenzene) were investigated using thermogravimetry (TG) and differential scanning calorimetry (DSC). The polystyrene-supported iodobenzene diacetate, synthesized from polystyrene, was a precursor to other three polymer-supported hypervalent iodine reagents (PS-HTIB, PS-HMIB and PS-BTI). The TG curves of hypervalent iodine reagents and their polymer analogues show mainly one-step mass loss behaviour, whereas enthalpy change (∆H) and onset temperature were calculated from a DSC curve which that shows hypervalent iodine reagents and their polymer analogues decompose endothermically. The results suggest that the polymer-supported hypervalent iodine reagents are more stable than hypervalent iodine reagents and therefore may be used in reactions without decomposition up to 350–410 °C in comparison to the polymer-supported hypervalent iodine reagents that are stable up to 132–160 °C.
A simple methodology to a unique macrocyclic α-amino acid (AAA) derivative involving three step synthetic sequence has been reported. In addition, various ruthenium based catalysts were studied to enhance the selectivity of the desired... more
A simple methodology to a unique macrocyclic α-amino acid (AAA) derivative involving three step synthetic sequence has been reported. In addition, various ruthenium based catalysts were studied to enhance the selectivity of the desired macrocyclic AAA derivative 6. The fluorescence behavior of these AAA derivatives 5 and 6 indicate their potential applications in biological sciences as biomarkers, ion sensors and
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In the present paper, we report an investigation into the high-pressure structural phase transition of rare earth antimonides (DySb and ErSb). A modified interaction potential model (MIPM) (including the covalency effect) has been... more
In the present paper, we report an investigation into the high-pressure structural phase transition of rare earth antimonides (DySb and ErSb). A modified interaction potential model (MIPM) (including the covalency effect) has been developed. Phase transition pressures are associated with a sudden collapse in volume, indicating the occurrence of a first order phase transition. At compressed volumes, these compounds are found in the CsCl phase. The phase transition pressures and associated volume collapses obtained from the potential model developed here show a generally better agreement with available experimental data than others available in the literature. The elastic constants and bulk modulus are also reported. Our results are, in general, in good agreement with experimental and theoretical data where available, and provide predictions where data are unavailable.
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Research Interests: Education, Intellectual Disability, Humans, Male, Karyotyping, and 3 moreTrisomy 21, Adult, and Syndrome
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On-farm experiments conducted on alluvial soils of Punjab with diverse crop rotations of different water requirement showed that at Nawanshahar, mean yield of wheat was similar for rice-wheat system (RWS; 4.0 Mg/ha) and maize-wheat system... more
On-farm experiments conducted on alluvial soils of Punjab with diverse crop rotations of different water requirement showed that at Nawanshahar, mean yield of wheat was similar for rice-wheat system (RWS; 4.0 Mg/ha) and maize-wheat system (MWS; 4.3 Mg/ha). Mean yield of maize was also similar in the MWS (4.4 Mg/ha) and maize-rapeseed system (MRS; 4.4 Mg/ha). Although output in gross returns (GR) and return on variable expenses (ROVE) were higher for RWS in Nawanshahar district, substituting maize for rice in the monsoon season is preferred because of savings in water. In Faridkot district, the monetary returns were higher for the cotton-wheat system (CWS), which makes judicious use of groundwater as compared to the non-traditional RWS. Soil organic carbon (SOC) concentration at Nawanshahar increased from a mean initial level of 0.44% to 0.50% when both rice and wheat residues were burned; 0.51% when rice straw was incorporated but wheat straw was removed; and 0.57% when both rice and wheat straw were incorporated. At Faridkot site, the SOC concentration increased from a mean initial level of 0.39% to 0.49% when both rice and wheat straw were incorporated. The positive effect of straw incorporation on soil quality was more pronounced in the light-textured soil (sandy loam) at Faridkot than in loamy soil at Nawanshahar. Soil bulk density at the Faridkot site decreased from 1.65 Mg/m to 1.58 Mg/m, and water infiltration rate increased from 6.1 mm/hr to 7.6 mm/hr. Straw incorporation increased soil organic carbon pool at the Faridkot site by 1 Mg/ha in 0-15 cm depth across a two year period. Comparative economics of residue incorporation in RWS across three years showed that, although the GR (Rs/ha) was the same in straw-burned and straw-incorporated treatments, the improvements in soil quality that the straw incorporation brings about for sustainable agriculture in the long-run offset any advantage of burning straw and gave higher net returns and benefit-cost ratio (BCR) in the short-term. Efficient on-farm water management using fertigation technology was demonstrated in a farmer's field for production of vegetables throughout the year. Diversified agriculture in the form of agroforestry and fish culture as alternative land-use options were also demonstrated in farmers' fields. Agroforestry interventions involving poplar trees with a range of intercrops were found to be useful cyclic interventions in the land-use and management strategy for sustainable agriculture in the intensively cultivated alluvial soils of Punjab.
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The Hardness locus on the short arm of chromosome 5D is the main determinant of grain texture in bread wheat. The Pina and Pinb genes are tightly linked at this locus, and the soft kernel texture phenotype results when both genes are... more
The Hardness locus on the short arm of chromosome 5D is the main determinant of grain texture in bread wheat. The Pina and Pinb genes are tightly linked at this locus, and the soft kernel texture phenotype results when both genes are present and encode the wild-type ...
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A fully parallel implementation of the multi-alphabet arithmetic-coding algorithm, an integral part of many lossless data compression systems, had so far eluded the research community. Although schemes were in existence for performing the... more
A fully parallel implementation of the multi-alphabet arithmetic-coding algorithm, an integral part of many lossless data compression systems, had so far eluded the research community. Although schemes were in existence for performing the encoding operation in parallel, the data dependencies involved in the decoding phase prevented its parallel execution. This paper presents a scheme for the parallel-pipelined implementation of both
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Research Interests: Genetics, Agricultural Biotechnology, Germ Cells, Karyotyping, Zinc, and 3 moreIron, Genome, and Triticum
Bacterial blight (BB) of rice caused by Xanthomonas oryzae pv oryzae (Xoo) is one of the major constraints to productivity in South-East Asia. The strategy of using major genes, singly or in combination, continues to be the most effective... more
Bacterial blight (BB) of rice caused by Xanthomonas oryzae pv oryzae (Xoo) is one of the major constraints to productivity in South-East Asia. The strategy of using major genes, singly or in combination, continues to be the most effective approach for BB management. Currently, more than two dozen genes have been designated but not all the known genes are effective against all the prevalent pathotypes. The challenge, therefore, is to continue to expand the gene pool of effective and potentially durable resistance genes. Wild species constitute an important reservoir of the resistance genes including BB. An accession of Oryza nivara (IRGC 81825) was found to be resistant to all the seven Xoo pathotypes prevalent in northern states of India. Inheritance and mapping of resistance in O. nivara was studied by using F2, BC2F2, BC3F1 and BC3F2 progenies of the cross involving Oryza sativa cv PR114 and the O. nivara acc. 81825 using the most virulent Xoo pathotype. Genetic analysis of the segregating progenies revealed that the BB resistance in O. nivara was conditioned by a single dominant gene. Bulked segregant analysis (BSA) of F2 population using 191 polymorphic SSR markers identified a approximately 35 centiMorgans (cM) chromosomal region on 4L, bracketed by RM317 and RM562, to be associated with BB resistance. Screening of BC3F1 and BC2F2 progenies and their genotyping with more than 30 polymorphic SSR markers in the region, covering Bacterial artificial chromosome (BAC) clone OSJNBb0085C12, led to mapping of the resistance gene between the STS markers based on annotated genes LOC_Os04g53060 and LOC_Os04g53120, which is approximately 38.4 kb. Since none of the known Xa genes, which are mapped on chromosome 4L, are effective against the Xoo pathotypes tested, the BB resistance gene identified and transferred from O. nivara is novel and is tentatively designated as Xa30(t). Homozygous resistant BC3F3 progenies with smallest introgression region have been identified.
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... References. Field Crops Research, 21 (1989) 277287 277 Elsevier Science Publishers BV, Amsterdam Printed in The Netherlands Effect of 12 Years' Rice Wheat Cropping Sequence and Fertilizer Use on Soil Properties and Crop Yields in... more
... References. Field Crops Research, 21 (1989) 277287 277 Elsevier Science Publishers BV, Amsterdam Printed in The Netherlands Effect of 12 Years' Rice Wheat Cropping Sequence and Fertilizer Use on Soil Properties and Crop Yields in a Sodic Soil ANAND SWARUP and ...
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Research Interests: Organic Chemistry, Pharmacy, Cytotoxicity, Humans, Candida albicans, and 13 moreAspergillus niger, Antimicrobial, Gram Positive Bacteria, CHEMICAL SCIENCES, European, Gram-negative bacteria, Anti-Bacterial Agents, Antifungal Agents, Microbial Sensitivity Tests, Cell Proliferation, Structure activity Relationship, Cell Survival, and Molecular Structure
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Indu Sharma1,∗ , Navtej Singh Bains1, Kuldeep Singh1 & Govinder Singh Nanda2 1Department of Plant Breeding, Genetics and Biotechnology, Punjab Agricultural, University, Ludhiana 141 004, Punjab, India; 2Director of Research, Punjab... more
Indu Sharma1,∗ , Navtej Singh Bains1, Kuldeep Singh1 & Govinder Singh Nanda2 1Department of Plant Breeding, Genetics and Biotechnology, Punjab Agricultural, University, Ludhiana 141 004, Punjab, India; 2Director of Research, Punjab Agricultural University, Ludhiana 141 ...
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A number of maize (Zea mays L.) genotypes were tested for their influence on induction and regeneration of haploid wheat (Triticum aestivum L.) embryos to improve further the efficiency of the wheat × maize system of haploid production.... more
A number of maize (Zea mays L.) genotypes were tested for their influence on induction and regeneration of haploid wheat (Triticum aestivum L.) embryos to improve further the efficiency of the wheat × maize system of haploid production. Fifteen maize genotypes were ...
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Dielectric ceramics in the BaO–Sm2O3–TiO2 ternary system have been synthesized and characterized. Solid solutions with the formula Ba6−3xSm8+2xTi18O54 with x=0.0, 0.2–0.7 have been synthesized, which are in the vicinity of BaO·Sm2O3·4TiO2... more
Dielectric ceramics in the BaO–Sm2O3–TiO2 ternary system have been synthesized and characterized. Solid solutions with the formula Ba6−3xSm8+2xTi18O54 with x=0.0, 0.2–0.7 have been synthesized, which are in the vicinity of BaO·Sm2O3·4TiO2 (consistent with x=0.5) ternary system. X-ray powder diffraction (XRD) analysis of synthesized specimens has been done from which lattice parameters as a function of composition (x) were determined. Crystal
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Hyperbaric Medicine is the fascinating use of barometric pressure for delivering increased oxygen dissolved in plasma to body tissues. Hyperbaric oxygen therapy (HBO) is a form of treatment in which a patient breathes 100% oxygen at... more
Hyperbaric Medicine is the fascinating use of barometric pressure for delivering increased oxygen dissolved in plasma to body tissues. Hyperbaric oxygen therapy (HBO) is a form of treatment in which a patient breathes 100% oxygen at higher than normal atmospheric ...
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Three populations of Botryodiplodia theobromae causing die-back and bark canker of pear in Punjab were analysed to know about the genetic diversity, gene flow, heterogeneity and the probable rate of spread of races capable of overcoming... more
Three populations of Botryodiplodia theobromae causing die-back and bark canker of pear in Punjab were analysed to know about the genetic diversity, gene flow, heterogeneity and the probable rate of spread of races capable of overcoming the resistance present in elite cultivars. There was no relationship between the morphologically similar isolates and their pathogenic behaviour. Majority of the isolates of
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Heterogeneous synthesis of monodisperse pure nickel nanoparticles in aqueous medium has been carried out using cetyltrimethylammonium bromide and a lower alkylammonium bromide mixture of tetraethylammonium bromide and tetrabutylammonium... more
Heterogeneous synthesis of monodisperse pure nickel nanoparticles in aqueous medium has been carried out using cetyltrimethylammonium bromide and a lower alkylammonium bromide mixture of tetraethylammonium bromide and tetrabutylammonium bromide. The presence ...
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The present study was conducted to investigate the sustained-release properties of Mimosa pudica seed mucilage. Matrix tablets of diclofenac sodium containing different proportions of mucilage and dibasic calcium phosphate as diluent were... more
The present study was conducted to investigate the sustained-release properties of Mimosa pudica seed mucilage. Matrix tablets of diclofenac sodium containing different proportions of mucilage and dibasic calcium phosphate as diluent were formulated by wet granulation method. The tablets had uniform physical appearance, average weight, drug content, and adequate hardness. The results of in vitro release conducted using USP type II dissolution rate apparatus, in a dissolution media comprising of 900 mL of 0.1 N HCl for 2 h followed by phosphate buffer (pH 6.8) for 24 h at 37 degrees C and 50 rpm, revealed that as the proportion of mucilage in the matrix was increased there was a corresponding decrease in the release of drug. Further, the matrix tablets were found to release the drug following Higuchi square root release kinetics, with the mechanism of release being diffusion for tablets containing higher proportion of mucilage and a combination of matrix erosion and diffusion for tablets containing smaller proportion of mucilage. The swelling and erosion studies revealed that, as the proportion of mucilage in tablets was increased, there was a corresponding increase in percent swelling and a decrease in percent erosion of tablets. The SEM photomicrographs showed gelling structures in tablets containing higher percentage of mucilage, while both pores and gelling structures were present on the surface of tablets containing smaller proportion of mucilage and commercial formulation. On comparative evaluation, the dissolution profile from formulation containing mucilage to drug in the proportion of 1:40 was found to be similar to the commercial sustained-release formulation of diclofenac.
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the paper is an effort to trace the history through various dimentions that would help to the readers a lot
it is all about how the various discipline had helped to the imprial tendencies and how long lasting white man burden and kipling's defence to all that ridiclues.
TWIN SHELL NEVER MEET AGAIN
TWIN SHELL NEVER MEET AGAIN
it is all abut the 'culture of self' that would lead us somewhere rather the the warfare policies that have led us nowhere.